{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T17:42:23Z","timestamp":1793036543003,"version":"4.5.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Universidad Aut\u00f3noma de Aguascalientes","award":["PIB17-2"],"award-info":[{"award-number":["PIB17-2"]}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda, Mexico","doi-asserted-by":"publisher","award":["450126\/598367"],"award-info":[{"award-number":["450126\/598367"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.micpath.2019.01.041","type":"journal-article","created":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T17:09:58Z","timestamp":1548868198000},"page":"56-63","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Morphological changes and phagocytic activity during the interaction of human neutrophils with Sporothrix schenckii: An in vitro model"],"prefix":"10.1016","volume":"129","author":[{"given":"Vicente","family":"Curtiellas-Pi\u00f1ol","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Ventura-Ju\u00e1rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estela","family":"Ruiz-Baca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5650-0712","authenticated-orcid":false,"given":"Yolanda","family":"Romo-Lozano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2019.01.041_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3767\/003158515X687416","article-title":"Phylogeography and evolutionary patterns in Sporothrix spanning more than 14 000 human and animal case reports","volume":"35","author":"Zhang","year":"2015","journal-title":"Persoonia"},{"key":"10.1016\/j.micpath.2019.01.041_bib2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s11046-011-9420-z","article-title":"insight into molecular phylogeny and epidemiology of Sporothrix schenckii species complex based on calmodulin-encoding gene analysis of Italian isolates","volume":"172","author":"Romeo","year":"2011","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micpath.2019.01.041_bib3","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1128\/JCM.00808-07","article-title":"three new Sporothrix species of clinical interest","volume":"45","author":"Marimon","year":"2007","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micpath.2019.01.041_bib4","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1128\/CMR.00007-11","article-title":"Sporothrix schenckii and Sporotrichosis","volume":"24","author":"Barros","year":"2011","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.micpath.2019.01.041_bib5","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1469-0691.2009.02824.x","article-title":"Different virulence levels of the species of Sporothrix in a murine model","volume":"15","author":"Arrillaga","year":"2009","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.micpath.2019.01.041_bib6","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1007\/s00284-016-1045-5","article-title":"Molecular components of the Sporothrix schenckii complex that induce immune response","volume":"73","author":"Alba","year":"2016","journal-title":"Curr. Microbiol."},{"key":"10.1016\/j.micpath.2019.01.041_bib7","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1046\/j.1365-3083.2003.01175.x","article-title":"Sporothrix schenckii lipid inhibits macrophage phagocytosis: involvement of nitric oxide and tumor necrosis factor-alpha","volume":"57","author":"Carlos","year":"2003","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.micpath.2019.01.041_bib8","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.riam.2013.09.017","article-title":"Cell wall proteins of Sporothrix schenckii as immunoprotective agents","volume":"31","author":"Alba","year":"2014","journal-title":"Rev. Iberoam. De. Micol."},{"key":"10.1016\/j.micpath.2019.01.041_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11046-009-9190-z","article-title":"Current research on the immune response to experimental sporotrichosis","volume":"168","author":"Carlos","year":"2009","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micpath.2019.01.041_bib10","first-page":"313","article-title":"Neutrophils: warriors and commanders in immune-mediated inflammatory diseases","volume":"34","author":"Casc\u00e3o","year":"2009","journal-title":"Acta Reumatol. Port."},{"key":"10.1016\/j.micpath.2019.01.041_bib11","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/j.micinf.2003.09.008","article-title":"Neutrophil granules and secretory vesicles in inflammation","volume":"5","author":"Faurschou","year":"2003","journal-title":"Microb. Infect."},{"key":"10.1016\/j.micpath.2019.01.041_bib12","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s12026-008-8049-6","article-title":"Neutrophil apoptosis and the resolution of infection","volume":"43","author":"Kennedy","year":"2009","journal-title":"Immunol. Res."},{"key":"10.1016\/j.micpath.2019.01.041_bib13","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.abb.2018.01.004","article-title":"Its role for host defense, inflammation, and neutrophil Function","volume":"640","author":"Myeloperoxidase","year":"2018","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.micpath.2019.01.041_bib14","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.intimp.2013.06.034","article-title":"Neutrophil cell surface receptors and their intracellular signals transduction pathways","volume":"17","author":"Futosi","year":"2013","journal-title":"Int. immunopharmacol."},{"key":"10.1016\/j.micpath.2019.01.041_bib15","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1365-3083.2011.02636.x","article-title":"Antibodies against Sporothrix schenckii enhance TNF-\u03b1 production and killing by macrophages","volume":"75","author":"Franco","year":"2012","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.micpath.2019.01.041_bib16","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1093\/mmy\/myu055","article-title":"Sporothrix schenckii yeasts induce ERK pathway activation and secretion of IL-6 and TNF-\u03b1 in rat mast cells, but no degranulation","volume":"52","author":"Romo","year":"2014","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micpath.2019.01.041_bib17","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1093\/infdis\/140.5.815","article-title":"Phagocytosis and intracellular fate of Sporothrix schenckii","volume":"140","author":"Cunningham","year":"1979","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micpath.2019.01.041_bib18","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1172\/JCI112603","article-title":"In vitro susceptibility of fungi to killing by neutrophil granulocytes discriminates between primary pathogenicity and Opportunism","volume":"78","author":"Schaffner","year":"1986","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.micpath.2019.01.041_bib19","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1067\/mjd.2000.107247","article-title":"Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications","volume":"43","author":"Sterling","year":"2000","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.micpath.2019.01.041_bib20","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1086\/522765","article-title":"Clinical Practice Guidelines for the management of sporotrichosis, 2007 update by the Infectious Disease Society of America","volume":"45","author":"Kauffman","year":"2007","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.micpath.2019.01.041_bib21","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0022-1759(74)90109-4","article-title":"Single-step separation of red blood cells. Granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque","volume":"5","author":"English","year":"1974","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.micpath.2019.01.041_bib22","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.micpath.2019.01.041_bib23","article-title":"Mounting samples in gelvatol or mowiol","volume":"1","author":"Harlow","year":"2006","journal-title":"Cold Spring Harb. Protoc."},{"key":"10.1016\/j.micpath.2019.01.041_bib24","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/0003-2697(73)90144-9","article-title":"A new sensitive colorimetric assay for peroxidase using 3,3\u2032-diaminobenzidine as hydrogen donor","volume":"55","author":"Herzog","year":"1973","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.micpath.2019.01.041_bib25","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/DAD.0b013e3181f5b622","article-title":"Sporotrichosis: clinical and histopathological manifestations","volume":"33","author":"Zhang","year":"2011","journal-title":"Am. J. Dermatopathol."},{"key":"10.1016\/j.micpath.2019.01.041_bib26","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1146\/annurev-pathol-020712-164023","article-title":"The multifaceted functions of neutrophils","volume":"9","author":"Mayadas","year":"2014","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.micpath.2019.01.041_bib27","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/2052-0492-1-13","article-title":"Neutrophil cell death in response to infection and its relation to coagulation","volume":"1","author":"Iba","year":"2013","journal-title":"J. Intensive Care"},{"key":"10.1016\/j.micpath.2019.01.041_bib28","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1073\/pnas.0405193102","article-title":"Myeloperoxidase mediates neutrophil activation by association with CD11b\/CD18 integrins","volume":"102","author":"Lau","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.micpath.2019.01.041_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/2349817","article-title":"Neutrophil-Mediated Regulation of Innate and Adaptive Immunity: The Role of Myeloperoxidase","volume":"2016","author":"Odobasic","year":"2016","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.micpath.2019.01.041_bib30","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0952-7915(01)00309-0","article-title":"Phagocytosis and innate immunity","volume":"14","author":"Greenberg","year":"2002","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.micpath.2019.01.041_bib31","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.it.2016.03.005","article-title":"Aging: a temporal dimension for neutrophils","volume":"37","author":"Adrover","year":"2016","journal-title":"Trends Immunol."},{"key":"10.1016\/j.micpath.2019.01.041_bib32","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/eji.201546022","article-title":"Challenges in the Characterization of Neutrophil extracellular traps. The truth in details","volume":"46","author":"Naccache","year":"2016","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.micpath.2019.01.041_bib33","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1111\/j.1462-5822.2005.00659.x","article-title":"Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms","volume":"8","author":"Urban","year":"2006","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.micpath.2019.01.041_bib34","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1182\/blood-2009-05-221606","article-title":"Restoration of NET formation by gene therapy in CGD controls aspergillosis","volume":"114","author":"Bianchi","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.micpath.2019.01.041_bib35","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.ijmm.2011.04.012","article-title":"Phagocyte responses towards Aspergillus fumigatus","volume":"301","author":"Hasenberg","year":"2011","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.micpath.2019.01.041_bib36","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1177\/1753425913484374","article-title":"Caspase-1: The inflammasome and beyond","volume":"20","author":"Sollberger","year":"2014","journal-title":"Innate Immun."},{"key":"10.1016\/j.micpath.2019.01.041_bib37","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1128\/JB.81.3.464-469.1961","article-title":"Dimorphism of Sporotrichum schenckii","volume":"81","author":"Howard","year":"1961","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2019.01.041_bib38","first-page":"59","article-title":"Ultrastructural studies of the mycelium to yeast transformation of Sporothrix schenckii","volume":"124","author":"Garrison","year":"1975","journal-title":"J. bact."},{"key":"10.1016\/j.micpath.2019.01.041_bib39","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1093\/femsre\/fuv035","article-title":"Fungal dimorphism: The switch from hyphae to yeast is a specialized morphogenetic adaptation allowing colonization of a host","volume":"39","author":"Boyce","year":"2015","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.micpath.2019.01.041_bib40","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/1471-2180-9-100","article-title":"Cytosolic phospholipase A2: a member of the signalling pathway of a new G protein alpha subunit in Sporothrix schenckii","volume":"9","author":"Valentin-Berrios","year":"2009","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micpath.2019.01.041_bib41","doi-asserted-by":"crossref","first-page":"2352","DOI":"10.1099\/mic.0.081794-0","article-title":"Sporothrix schenckii complex biology: environment and fungal pathogenicity","volume":"160","author":"T\u00e9llez","year":"2014","journal-title":"Microbiol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401018315304?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401018315304?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T15:50:43Z","timestamp":1606319443000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401018315304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":41,"alternative-id":["S0882401018315304"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2019.01.041","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Morphological changes and phagocytic activity during the interaction of human neutrophils with Sporothrix schenckii: An in vitro model","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2019.01.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}