{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:29:33Z","timestamp":1790828973818,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100013238","name":"Faculty of Medicine Siriraj Hospital, Mahidol University","doi-asserted-by":"publisher","award":["R015832019"],"award-info":[{"award-number":["R015832019"]}],"id":[{"id":"10.13039\/501100013238","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.micpath.2019.05.008","type":"journal-article","created":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T14:08:54Z","timestamp":1557324534000},"page":"215-221","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Replication and cytokine profiles of different subgenotypes of enterovirus 71 isolated from Thai patients in peripheral blood mononuclear cells"],"prefix":"10.1016","volume":"132","author":[{"given":"Artit","family":"Wongsa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Egarit","family":"Noulsri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chintana","family":"Phawong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilaipan","family":"Puthavathana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boonrat","family":"Tassaneetrithep","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2019.05.008_bib1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1186\/1471-2334-11-270","article-title":"The changing seroepidemiology of enterovirus 71 infection among children and adolescents in Singapore","volume":"11","author":"Ang","year":"2011","journal-title":"BMC Infect. Dis."},{"issue":"1","key":"10.1016\/j.micpath.2019.05.008_bib2","doi-asserted-by":"crossref","first-page":"92","DOI":"10.3201\/eid2201.151323","article-title":"Seroepidemiology of human enterovirus 71 infection among children","volume":"22","author":"Horwood","year":"2016","journal-title":"Cambodia. Emerg Infect Dis."},{"key":"10.1016\/j.micpath.2019.05.008_bib3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1423-0127-21-16","article-title":"Epidemiology and seroepidemiology of human enterovirus 71 among Thai populations","volume":"21","author":"Linsuwanon","year":"2014","journal-title":"J. Biomed. Sci."},{"issue":"11","key":"10.1016\/j.micpath.2019.05.008_bib4","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/S1473-3099(10)70194-8","article-title":"Virology, epidemiology, pathogenesis, and control of enterovirus 71","volume":"10","author":"Solomon","year":"2010","journal-title":"Lancet Infect. Dis."},{"issue":"4","key":"10.1016\/j.micpath.2019.05.008_bib5","doi-asserted-by":"crossref","first-page":"641","DOI":"10.3201\/eid1904.121666","article-title":"Hand, foot, and mouth disease caused by coxsackievirus A6, Thailand, 2012","volume":"19","author":"Puenpa","year":"2013","journal-title":"Emerg. Infect. Dis."},{"issue":"6","key":"10.1016\/j.micpath.2019.05.008_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0098888","article-title":"Prevalence and characterization of enterovirus infections among pediatric patients with hand foot mouth disease, herpangina and influenza like illness in Thailand, 2012","volume":"9","author":"Puenpa","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2019.05.008_bib7","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1186\/1471-2334-12-224","article-title":"Excessive proinflammatory cytokine and chemokine responses of human monocyte-derived macrophages to enterovirus 71 infection","volume":"12","author":"Gong","year":"2012","journal-title":"BMC Infect. Dis."},{"issue":"6","key":"10.1016\/j.micpath.2019.05.008_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0067430","article-title":"Comparative study of the cytokine\/chemokine response in children with differing disease severity in enterovirus 71-induced hand, foot, and mouth disease","volume":"8","author":"Zhang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2019.05.008_bib9","doi-asserted-by":"crossref","first-page":"876241","DOI":"10.1155\/2012\/876241","article-title":"Cytokine immunopathogenesis of enterovirus 71 brain stem encephalitis","volume":"2012","author":"Wang","year":"2012","journal-title":"Clin. Dev. Immunol."},{"issue":"1","key":"10.1016\/j.micpath.2019.05.008_bib10","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1186\/s12985-018-1074-8","article-title":"Seroprevalence of antibodies to enterovirus 71 and coxsackievirus A16 among people of various age groups in a northeast province of Thailand","volume":"15","author":"Lerdsamran","year":"2018","journal-title":"Virol. J."},{"issue":"16","key":"10.1016\/j.micpath.2019.05.008_bib11","doi-asserted-by":"crossref","first-page":"7732","DOI":"10.1128\/JVI.75.16.7732-7738.2001","article-title":"Phylogenetic analysis of enterovirus 71 strains isolated during linked epidemics in Malaysia, Singapore, and Western Australia","volume":"75","author":"McMinn","year":"2001","journal-title":"J. Virol."},{"issue":"5","key":"10.1016\/j.micpath.2019.05.008_bib12","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1086\/511073","article-title":"Human enterovirus 71 disease in Sarawak, Malaysia: a prospective clinical, virological, and molecular epidemiological study","volume":"44","author":"Ooi","year":"2007","journal-title":"Clin. Infect. Dis."},{"issue":"9","key":"10.1016\/j.micpath.2019.05.008_bib13","doi-asserted-by":"crossref","first-page":"2826","DOI":"10.1128\/JCM.00507-09","article-title":"Epidemiology of enterovirus 71 in The Netherlands, 1963 to 2008","volume":"47","author":"van der Sanden","year":"2009","journal-title":"J. Clin. Microbiol."},{"issue":"1","key":"10.1016\/j.micpath.2019.05.008_bib14","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/JCM.40.1.10-15.2002","article-title":"Change of major genotype of enterovirus 71 in outbreaks of hand-foot-and-mouth disease in Taiwan between 1998 and 2000","volume":"40","author":"Wang","year":"2002","journal-title":"J. Clin. Microbiol."},{"issue":"2","key":"10.1016\/j.micpath.2019.05.008_bib15","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0168-1702(00)00162-3","article-title":"Genetic analysis of enterovirus 71 isolated from fatal and non-fatal cases of hand, foot and mouth disease during an epidemic in Taiwan, 1998","volume":"68","author":"Shih","year":"2000","journal-title":"Virus Res."},{"issue":"12","key":"10.1016\/j.micpath.2019.05.008_bib16","doi-asserted-by":"crossref","first-page":"9969","DOI":"10.1128\/JVI.73.12.9969-9975.1999","article-title":"Molecular epidemiology and evolution of enterovirus 71 strains isolated from 1970 to 1998","volume":"73","author":"Brown","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2019.05.008_bib17","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.virol.2016.04.016","article-title":"Susceptibility of human tonsillar epithelial cells to enterovirus 71 with normal cytokine response","volume":"494","author":"Xie","year":"2016","journal-title":"Virology"},{"issue":"4","key":"10.1016\/j.micpath.2019.05.008_bib18","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S0002-9440(10)63496-7","article-title":"Coxsackievirus B3 and the neonatal CNS: the roles of stem cells, developing neurons, and apoptosis in infection, viral dissemination, and disease","volume":"163","author":"Feuer","year":"2003","journal-title":"Am. J. Pathol."},{"issue":"10","key":"10.1016\/j.micpath.2019.05.008_bib19","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1128\/CVI.00108-10","article-title":"Enterovirus 71 infection of monocytes with antibody-dependent enhancement","volume":"17","author":"Wang","year":"2010","journal-title":"Clin. Vaccine Immunol.: CVI."},{"issue":"Pt 6","key":"10.1016\/j.micpath.2019.05.008_bib20","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1099\/0022-1317-81-6-1413","article-title":"Cellular receptors for viruses: links to tropism and pathogenesis","volume":"81","author":"Schneider-Schaulies","year":"2000","journal-title":"J. Gen. Virol."},{"issue":"8","key":"10.1016\/j.micpath.2019.05.008_bib21","doi-asserted-by":"crossref","first-page":"4792","DOI":"10.1128\/JVI.69.8.4792-4796.1995","article-title":"Antiviral defense in mice lacking both alpha\/beta and gamma interferon receptors","volume":"69","author":"van den Broek","year":"1995","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.micpath.2019.05.008_bib22","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1128\/JVI.06103-11","article-title":"A non-mouse-adapted enterovirus 71 (EV71) strain exhibits neurotropism, causing neurological manifestations in a novel mouse model of EV71 infection","volume":"86","author":"Khong","year":"2012","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.micpath.2019.05.008_bib23","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1128\/JVI.01855-12","article-title":"Cleavage of interferon regulatory factor 7 by enterovirus 71 3C suppresses cellular responses","volume":"87","author":"Lei","year":"2013","journal-title":"J. Virol."},{"issue":"16","key":"10.1016\/j.micpath.2019.05.008_bib24","doi-asserted-by":"crossref","first-page":"8051","DOI":"10.1128\/JVI.02491-09","article-title":"The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses","volume":"84","author":"Lei","year":"2010","journal-title":"J. Virol."},{"issue":"11","key":"10.1016\/j.micpath.2019.05.008_bib25","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1002\/jmv.23377","article-title":"Enterovirus 71 blocks selectively type I interferon production through the 3C viral protein in mice","volume":"84","author":"Lee","year":"2012","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.micpath.2019.05.008_bib26","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/1471-2180-14-147","article-title":"Activation of JNK1\/2 and p38 MAPK signaling pathways promotes enterovirus 71 infection in immature dendritic cells","volume":"14","author":"Peng","year":"2014","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micpath.2019.05.008_bib27","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-2172-6-13","article-title":"Standardization of cytokine flow cytometry assays","volume":"6","author":"Maecker","year":"2005","journal-title":"BMC Immunol."},{"issue":"1\u20132","key":"10.1016\/j.micpath.2019.05.008_bib28","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jim.2007.09.001","article-title":"Cell permeabilization for the assessment of T lymphocyte polyfunctional capacity","volume":"328","author":"Papagno","year":"2007","journal-title":"J. Immunol. Methods"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401019301536?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401019301536?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T08:41:44Z","timestamp":1607676104000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401019301536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":28,"alternative-id":["S0882401019301536"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2019.05.008","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Replication and cytokine profiles of different subgenotypes of enterovirus 71 isolated from Thai patients in peripheral blood mononuclear cells","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2019.05.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}