{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T20:08:33Z","timestamp":1780344513106,"version":"3.54.1"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Programa de Desarrollo de las Ciencias B\u00e1sicas"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.micpath.2019.103611","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T08:49:40Z","timestamp":1561452580000},"page":"103611","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["On sulfonamide resistance, sul genes, class 1 integrons and their horizontal transfer in Escherichia coli"],"prefix":"10.1016","volume":"135","author":[{"given":"Mar\u00eda Elo\u00edsa","family":"Poey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda F.","family":"Azpiroz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magela","family":"Lavi\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2019.103611_bib1","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1128\/AAC.21.2.288","article-title":"Bactericidal activity of trimethoprim alone and in combination with sulfamethoxazole on susceptible and resistant Escherichia coli K12","volume":"21","author":"Amyes","year":"1982","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micpath.2019.103611_bib2","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1111\/j.1574-6976.2011.00289.x","article-title":"Persistence of antibiotic resistance in bacterial populations","volume":"35","author":"Andersson","year":"2011","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.micpath.2019.103611_bib3","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1128\/AAC.49.2.836-839.2005","article-title":"Dissemination of sulfonamide resistance genes (sul1, sul2, and sul3) in Portuguese Salmonella enterica strains and relation with integrons","volume":"49","author":"Antunes","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micpath.2019.103611_bib4","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1146\/annurev-genet-102209-163504","volume":"44","author":"Cambray","year":"2010","journal-title":"Integrons. Annu. Rev. Genet."},{"key":"10.1016\/j.micpath.2019.103611_bib5","doi-asserted-by":"crossref","first-page":"4539","DOI":"10.1093\/nar\/gkw319","article-title":"Identification and analysis of integrons and cassette arrays in bacterial genomes","volume":"44","author":"Cury","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2019.103611_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0012754","article-title":"Distribution of class 1 integrons with IS26-mediated deletions in their 3'-conserved segments in Escherichia coli of human and animal origin","volume":"5","author":"Dawes","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2019.103611_bib7","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1099\/mic.0.000099","article-title":"Global dissemination patterns of common gene cassette arrays in class 1 integrons","volume":"161","author":"Domingues","year":"2015","journal-title":"An. Microbiol."},{"key":"10.1016\/j.micpath.2019.103611_bib8","first-page":"12","article-title":"Antibiotic resistance: what is so special about multidrug-resistant Gram-negative bacteria?","author":"Exner","year":"2017","journal-title":"GMS Hyg. Infect. Control"},{"key":"10.1016\/j.micpath.2019.103611_bib9","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1128\/jcm.5.6.650-655.1977","article-title":"Selective and enhanced recovery of group A and B Streptococci from throat cultures with sheep blood agar containing sulfamethoxazole and trimethoprim","volume":"5","author":"Gunn","year":"1977","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micpath.2019.103611_bib10","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/978-1-60327-853-9_6","article-title":"The integron\/gene cassette system: an active player in bacterial adaptation","volume":"532","author":"Labbate","year":"2009","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.micpath.2019.103611_bib11","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1086\/345880","article-title":"Multidrug resistance among Enterobacteriaceae is strongly associated with the presence of integrons and is independent of species or isolate origin","volume":"187","author":"Leverstein-Van Hall","year":"2003","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micpath.2019.103611_bib12","series-title":"Escherichia coli and Salmonella: Cellular and Molecular Biology","author":"Neidhardt","year":"1996"},{"key":"10.1016\/j.micpath.2019.103611_bib13","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1111\/j.1574-6976.2011.00277.x","article-title":"Analysis of antibiotic resistance regions in Gram-negative bacteria","volume":"35","author":"Partridge","year":"2011","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.micpath.2019.103611_bib14","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1128\/AAC.50.4.1411-1418.2006","article-title":"Comparative analysis of chromosome-encoded microcins","volume":"50","author":"Poey","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micpath.2019.103611_bib15","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.micpath.2012.02.006","article-title":"Virulence profiles in uropathogenic Escherichia coli isolated from pregnant women and children with urinary tract abnormalities","volume":"52","author":"Poey","year":"2012","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2019.103611_bib16","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.micpath.2014.11.002","article-title":"Integrons in uropathogenic Escherichia coli and their relationship with phylogeny and virulence","volume":"77","author":"Poey","year":"2014","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2019.103611_bib17","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.micpath.2018.02.006","article-title":"Horizontal transfer of class 1 integrons from uropathogenic Escherichia coli to E. coli K12","volume":"117","author":"Poey","year":"2018","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2019.103611_bib18","first-page":"369","article-title":"Escherichia coli K12 strains for use in the identification and characterization of colicins","volume":"131","author":"Pugsley","year":"1985","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.micpath.2019.103611_bib19","series-title":"Molecular Cloning: a Laboratory Manual","author":"Sambrook","year":"1989"},{"key":"10.1016\/j.micpath.2019.103611_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1586\/eri.09.117","article-title":"Sulfonamides and trimethoprim","volume":"8","author":"Sk\u00f6ld","year":"2010","journal-title":"Expert Rev. Anti Infect. Ther."},{"key":"10.1016\/j.micpath.2019.103611_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0128797","article-title":"Integron, plasmid and host strain characteristics of Escherichia coli from humans and food included in the Norwegian Antimicrobial Resistance Monitoring Programs","volume":"10","author":"Sunde","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2019.103611_bib22","series-title":"Antibiotics. Actions, Origins, Resistance","author":"Walsh","year":"2003"},{"key":"10.1016\/j.micpath.2019.103611_bib23","author":"World Health Organization"},{"key":"10.1016\/j.micpath.2019.103611_bib24","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s40168-018-0516-2","article-title":"Conserved phylogenetic distribution and limited antibiotic resistance of class 1 integrons revealed by assessing the bacterial genome and plasmid collection","volume":"6","author":"Zhang","year":"2018","journal-title":"Microbiome"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088240101930645X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088240101930645X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:21:43Z","timestamp":1760109703000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S088240101930645X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":24,"alternative-id":["S088240101930645X"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2019.103611","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"On sulfonamide resistance, sul genes, class 1 integrons and their horizontal transfer in Escherichia coli","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2019.103611","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103611"}}