{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T16:39:05Z","timestamp":1785515945047,"version":"3.56.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002402","name":"Sun Yat-sen University","doi-asserted-by":"publisher","award":["17kypy56"],"award-info":[{"award-number":["17kypy56"]}],"id":[{"id":"10.13039\/501100002402","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.micpath.2020.104359","type":"journal-article","created":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T13:06:44Z","timestamp":1593176804000},"page":"104359","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":54,"special_numbering":"C","title":["Dysbiosis of gut microbiota in adult idiopathic membranous nephropathy with nephrotic syndrome"],"prefix":"10.1016","volume":"147","author":[{"given":"Jun","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenying","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialing","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanqing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanqi","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5615","key":"10.1016\/j.micpath.2020.104359_bib1","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1126\/science.1080029","article-title":"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis","volume":"299","author":"Xu","year":"2003","journal-title":"Science"},{"issue":"5728","key":"10.1016\/j.micpath.2020.104359_bib2","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1126\/science.1110591","article-title":"Diversity of the human intestinal microbial flora","volume":"308","author":"Eckburg","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.micpath.2020.104359_bib3","first-page":"26164","article-title":"Contribution of diet to the composition of the human gut microbiota","volume":"26","author":"Graf","year":"2015","journal-title":"Microb. Ecol. Health Dis."},{"issue":"5","key":"10.1016\/j.micpath.2020.104359_bib4","doi-asserted-by":"crossref","DOI":"10.3945\/jn.114.194936","article-title":"Progress and challenges in developing metabolic footprints from diet in human gut microbial cometabolism","volume":"145","author":"Duffy","year":"2015","journal-title":"J. Nutr."},{"issue":"7122","key":"10.1016\/j.micpath.2020.104359_bib5","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1038\/4441009a","article-title":"Physiology - obesity and gut flora","volume":"444","author":"Bajzer","year":"2006","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.micpath.2020.104359_bib6","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1161\/CIRCRESAHA.117.309715","article-title":"Gut microbiota in cardiovascular health and disease","volume":"120","author":"Tang","year":"2017","journal-title":"Circ. Res."},{"issue":"25","key":"10.1016\/j.micpath.2020.104359_bib7","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1093\/eurheartj\/ehy226","article-title":"Gut microbial diversity is associated with lower arterial stiffness in women","volume":"39","author":"Menni","year":"2018","journal-title":"Eur. Heart J."},{"issue":"10","key":"10.1016\/j.micpath.2020.104359_bib8","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.2337\/dc10-0556","article-title":"Obesity, diabetes, and gut microbiota the hygiene hypothesis expanded?","volume":"33","author":"Musso","year":"2010","journal-title":"Diabetes Care"},{"issue":"2","key":"10.1016\/j.micpath.2020.104359_bib9","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1038\/ki.2012.345","article-title":"Chronic kidney disease alters intestinal microbial flora","volume":"83","author":"Vaziri","year":"2013","journal-title":"Kidney Int."},{"key":"10.1016\/j.micpath.2020.104359_bib10","article-title":"Alteration of the gut microbiota in Chinese population with chronic kidney disease","volume":"7","author":"Jiang","year":"2017","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.micpath.2020.104359_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/toxins10070300","article-title":"Impact of altered intestinal microbiota on chronic kidney disease progression","volume":"10","author":"Castillo-Rodriguez","year":"2018","journal-title":"Toxins"},{"issue":"6","key":"10.1016\/j.micpath.2020.104359_bib12","doi-asserted-by":"crossref","first-page":"F1211","DOI":"10.1152\/ajprenal.00298.2018","article-title":"Chronic kidney disease and the gut microbiome","volume":"316","author":"Hobby","year":"2019","journal-title":"Am. J. Physiol. Ren."},{"issue":"11","key":"10.1016\/j.micpath.2020.104359_bib13","doi-asserted-by":"crossref","first-page":"825","DOI":"10.7326\/0003-4819-158-11-201306040-00007","article-title":"Kidney Disease: improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group M. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline","volume":"158","author":"Stevens","year":"2013","journal-title":"Ann. Intern. Med."},{"issue":"10","key":"10.1016\/j.micpath.2020.104359_bib14","doi-asserted-by":"crossref","first-page":"2937","DOI":"10.1681\/ASN.2006040368","article-title":"Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease","volume":"17","author":"Ma","year":"2006","journal-title":"J. Am. Soc. Nephrol."},{"issue":"19","key":"10.1016\/j.micpath.2020.104359_bib15","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1093\/bioinformatics\/btq461","article-title":"Search and clustering orders of magnitude faster than BLAST","volume":"26","author":"Edgar","year":"2010","journal-title":"Bioinformatics"},{"issue":"6","key":"10.1016\/j.micpath.2020.104359_bib16","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Segata","year":"2011","journal-title":"Genome Biol."},{"issue":"3","key":"10.1016\/j.micpath.2020.104359_bib17","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1159\/000487557","article-title":"Gut microbiota dysbiosis in children with relapsing idiopathic nephrotic syndrome","volume":"47","author":"Tsuji","year":"2018","journal-title":"Am. J. Nephrol."},{"issue":"3","key":"10.1016\/j.micpath.2020.104359_bib18","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1159\/000360010","article-title":"Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD","volume":"39","author":"Wong","year":"2014","journal-title":"Am. J. Nephrol."},{"issue":"1","key":"10.1016\/j.micpath.2020.104359_bib19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1079\/PNS2002207","article-title":"Regulation of short-chain fatty acid production","volume":"62","author":"Macfarlane","year":"2003","journal-title":"Proc. Nutr. Soc."},{"key":"10.1016\/j.micpath.2020.104359_bib20","article-title":"Enrichment of gut-derived Fusobacterium is associated with suboptimal immune recovery in HIV-infected individuals","volume":"8","author":"Lee","year":"2018","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.micpath.2020.104359_bib21","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/s41440-018-0144-z","article-title":"Gut microbiota and inflammation in chronic kidney disease and their roles in the development of cardiovascular disease","volume":"42","author":"Onal","year":"2019","journal-title":"Hypertens. Res. : Off. J. Jpn. Soc. Hypertens."},{"issue":"5","key":"10.1016\/j.micpath.2020.104359_bib22","first-page":"3461","article-title":"Dysbiosis of Gram-negative gut microbiota and the associated serum lipopolysaccharide exacerbates inflammation in type 2 diabetic patients with chronic kidney disease","volume":"18","author":"Salguero","year":"2019","journal-title":"Exp. Therapeut. Med."},{"key":"10.1016\/j.micpath.2020.104359_bib23","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.3389\/fmicb.2017.01765","article-title":"Next-generation beneficial microbes: the case of Akkermansia muciniphila","volume":"8","author":"Cani","year":"2017","journal-title":"Front. Microbiol."},{"issue":"1","key":"10.1016\/j.micpath.2020.104359_bib24","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/1462-2920.13589","article-title":"Formation of propionate and butyrate by the human colonic microbiota","volume":"19","author":"Louis","year":"2017","journal-title":"Environ. Microbiol."},{"issue":"1","key":"10.1016\/j.micpath.2020.104359_bib25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1017\/S0029665114001463","article-title":"Links between diet, gut microbiota composition and gut metabolism","volume":"74","author":"Flint","year":"2015","journal-title":"Proc. Nutr. Soc."},{"issue":"4","key":"10.1016\/j.micpath.2020.104359_bib26","doi-asserted-by":"crossref","DOI":"10.1002\/mbo3.678","article-title":"Altered gut microbiota and microbial biomarkers associated with chronic kidney disease","volume":"8","author":"Lun","year":"2019","journal-title":"Microbiologyopen"},{"issue":"8","key":"10.1016\/j.micpath.2020.104359_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0134311","article-title":"Gut-microbiota-Metabolite Axis in early renal function decline","volume":"10","author":"Barrios","year":"2015","journal-title":"PloS One"},{"issue":"5","key":"10.1016\/j.micpath.2020.104359_bib28","doi-asserted-by":"crossref","DOI":"10.3390\/toxins10050202","article-title":"Role of uremic toxins for kidney, cardiovascular, and bone dysfunction","volume":"10","author":"Fujii","year":"2018","journal-title":"Toxins"},{"issue":"2","key":"10.1016\/j.micpath.2020.104359_bib29","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1152\/physiolgenomics.00081.2016","article-title":"Alterations in the gut microbiota can elicit hypertension in rats","volume":"49","author":"Adnan","year":"2017","journal-title":"Physiol. Genom."},{"issue":"1","key":"10.1016\/j.micpath.2020.104359_bib30","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s40168-016-0222-x","article-title":"Gut microbiota dysbiosis contributes to the development of hypertension","volume":"5","author":"Li","year":"2017","journal-title":"Microbiome"},{"issue":"6","key":"10.1016\/j.micpath.2020.104359_bib31","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.cell.2016.05.041","article-title":"From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites","volume":"165","author":"Koh","year":"2016","journal-title":"Cell"},{"issue":"7480","key":"10.1016\/j.micpath.2020.104359_bib32","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/nature12721","article-title":"Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells","volume":"504","author":"Furusawa","year":"2013","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.micpath.2020.104359_bib33","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1681\/ASN.2013080905","article-title":"The gut microbiome, kidney disease, and targeted interventions","volume":"25","author":"Ramezani","year":"2014","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.micpath.2020.104359_bib34","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.mehy.2017.07.035","article-title":"Role of gut microbiota in idiopathic nephrotic syndrome in children","volume":"108","author":"Kaneko","year":"2017","journal-title":"Med. Hypotheses"},{"issue":"1","key":"10.1016\/j.micpath.2020.104359_bib35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa0810457","article-title":"M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy","volume":"361","author":"Beck","year":"2009","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.micpath.2020.104359_bib36","doi-asserted-by":"crossref","DOI":"10.1002\/cti2.1004","article-title":"Regulatory T cells in renal disease","volume":"7","author":"Alikhan","year":"2018","journal-title":"Clin. Transl. Immunol."},{"key":"10.1016\/j.micpath.2020.104359_bib37","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.3389\/fmicb.2016.01081","article-title":"The gut microbiota in immune-mediated inflammatory diseases","volume":"7","author":"Forbes","year":"2016","journal-title":"Front. Microbiol."},{"issue":"2","key":"10.1016\/j.micpath.2020.104359_bib38","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1753-4887.2007.tb00282.x","article-title":"Influence of dietary fiber on inflammatory bowel disease and colon cancer: importance of fermentation pattern","volume":"65","author":"Rose","year":"2007","journal-title":"Nutr. Rev."},{"issue":"1","key":"10.1016\/j.micpath.2020.104359_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00535-016-1242-9","article-title":"Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases","volume":"52","author":"Sun","year":"2017","journal-title":"J. Gastroenterol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401020307257?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401020307257?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T17:39:43Z","timestamp":1778693983000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401020307257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":39,"alternative-id":["S0882401020307257"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2020.104359","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dysbiosis of gut microbiota in adult idiopathic membranous nephropathy with nephrotic syndrome","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2020.104359","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104359"}}