{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:18:46Z","timestamp":1791839926299,"version":"4.3.4"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005285","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Goi\u00e1s","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.micpath.2021.104864","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T16:44:14Z","timestamp":1616517854000},"page":"104864","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Paracoccidioides brasiliensis induces IL-32 and is controlled by IL-15\/IL-32\/vitamin D pathway in vitro"],"prefix":"10.1016","volume":"154","author":[{"given":"Grazzielle","family":"Guimar\u00e3es de Matos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Marina","family":"Barroso de Figueiredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Hugo","family":"Diniz Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Luiz de Lima Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline Carvalho","family":"Bastista","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clayton Luiz","family":"Borges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9lia","family":"Maria de Almeida Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6166-9830","authenticated-orcid":false,"given":"Leo A.B.","family":"Joosten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1tima","family":"Ribeiro-Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2021.104864_bib1","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1590\/0037-8682-0230-2017","article-title":"Brazilian guidelines for the clinical management of paracoccidioidomycosis","volume":"50","author":"Shikanai-Yasuda","year":"2017","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"10.1016\/j.micpath.2021.104864_bib2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004397","article-title":"Paracoccidioides species complex: ecology, phylogeny, sexual reproduction, and virulence","volume":"10","author":"Teixeira","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.micpath.2021.104864_bib3","doi-asserted-by":"crossref","first-page":"224","DOI":"10.2174\/1874285801711010224","article-title":"Paracoccidioidomycosis: current perspectives from Brazil","volume":"11","author":"Mendes","year":"2017","journal-title":"Open Microbiol. J."},{"key":"10.1016\/j.micpath.2021.104864_bib4","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1590\/S0036-46652014000200006","article-title":"Reduc\u00e7\u00e3o na preval\u00eancia da forma aguda\/subaguda da paracoccidioidomicose em Mato Grosso do Sul","volume":"56","author":"Fabris","year":"2014","journal-title":"Brasil, Rev. Inst. Med. Trop. Sao Paulo."},{"key":"10.1016\/j.micpath.2021.104864_bib5","doi-asserted-by":"crossref","first-page":"722","DOI":"10.3109\/13693780802641425","article-title":"TLR-2, TLR-4 and dectin-1 expression in human monocytes and neutrophils stimulated by Paracoccidioides brasiliensis","volume":"47","author":"Bonfim","year":"2009","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micpath.2021.104864_bib6","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1365-3083.2009.02351.x","article-title":"Role of TLR2 and TLR4 in human neutrophil functions against Paracoccidioides brasiliensis","volume":"71","author":"Acorci-Val\u00e9rio","year":"2010","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.micpath.2021.104864_bib7","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.imbio.2015.09.003","article-title":"Participation of dectin-1 receptor on NETs release against Paracoccidioides brasiliensis: role on extracellular killing","volume":"221","author":"Bachiega","year":"2016","journal-title":"Immunobiology"},{"key":"10.1016\/j.micpath.2021.104864_bib8","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.cyto.2006.08.005","article-title":"Flow-cytometric analysis of cytokine production in human paracoccidioidomycosis","volume":"35","author":"Mamoni","year":"2006","journal-title":"Cytokine"},{"key":"10.1016\/j.micpath.2021.104864_bib9","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S1286-4579(01)01521-0","article-title":"Cytokines and lymphocyte proliferation in juvenile and adult forms of paracoccidioidomycosis: comparison with infected and non-infected controls","volume":"4","author":"Oliveira","year":"2002","journal-title":"Microb. Infect."},{"key":"10.1016\/j.micpath.2021.104864_bib10","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.jinf.2013.07.019","article-title":"Characterization of the immune response in human paracoccidioidomycosis","volume":"67","author":"de Castro","year":"2013","journal-title":"J. Infect."},{"key":"10.1016\/j.micpath.2021.104864_bib11","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/intimm\/dxh339","article-title":"Involvement of IL-32 in activation-induced cell death in T cells","volume":"18","author":"Goda","year":"2006","journal-title":"Int. Immunol."},{"key":"10.1016\/j.micpath.2021.104864_bib12","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/j.1365-2567.2008.02917.x","article-title":"Identification of the most active interleukin-32 isoform","volume":"126","author":"Da Choi","year":"2009","journal-title":"Immunology"},{"key":"10.1016\/j.micpath.2021.104864_bib13","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.cyto.2009.03.007","article-title":"Molecular characterization of IL-32 in human endothelial cells","volume":"46","author":"Kobayashi","year":"2009","journal-title":"Cytokine"},{"key":"10.1016\/j.micpath.2021.104864_bib14","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.biochi.2014.01.013","article-title":"Interaction network mapping among IL-32 isoforms","volume":"101","author":"Kang","year":"2014","journal-title":"Biochimie"},{"key":"10.1016\/j.micpath.2021.104864_bib15","first-page":"131","article-title":"Interleukin-32: a cytokine and inducer of TNF\u03b1","volume":"22","author":"Kim","year":"2005","journal-title":"Immunity"},{"key":"10.1016\/j.micpath.2021.104864_bib16","doi-asserted-by":"crossref","first-page":"3883","DOI":"10.1073\/pnas.0813334106","article-title":"IL-32-dependent effects of IL-1\u03b2 on endothelial cell functions","volume":"106","author":"Nold-Petry","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.micpath.2021.104864_bib17","first-page":"2016","article-title":"IL-32: a novel pluripotent inflammatory interleukin, towards gastric inflammation, gastric cancer, and chronic rhino sinusitis","author":"Khawar","year":"2016","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.micpath.2021.104864_bib18","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1371\/journal.pmed.0030277","article-title":"Mycobacterium tuberculosis induces interleukin-32 production through a caspase-1\/IL-18\/interferon-\u03b3-dependent mechanism","volume":"3","author":"Netea","year":"2006","journal-title":"PLoS Med."},{"key":"10.1016\/j.micpath.2021.104864_bib19","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.imlet.2008.01.007","article-title":"Increased level of IL-32 during human immunodeficiency virus infection suppresses HIV replication","volume":"117","author":"Rasool","year":"2008","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.micpath.2021.104864_bib20","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1093\/intimm\/dxr075","article-title":"IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease","volume":"23","author":"Bai","year":"2011","journal-title":"Int. Immunol."},{"key":"10.1016\/j.micpath.2021.104864_bib21","article-title":"Interleukin 32\u03b3 (IL-32\u03b3) is highly expressed in cutaneous and mucosal lesions of American Tegumentary Leishmaniasis patients: association with tumor necrosis factor (TNF) and IL-10","volume":"14","author":"Galdino Junior","year":"2014","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.micpath.2021.104864_bib22","first-page":"10","article-title":"IL-32\u03b3 promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis","author":"Gomes","year":"2017","journal-title":"Parasites Vectors"},{"key":"10.1016\/j.micpath.2021.104864_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005413","article-title":"Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species","volume":"11","author":"dos Santos","year":"2017","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.micpath.2021.104864_bib24","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3009546","article-title":"IL-32 is a molecular marker of a host defense network in human tuberculosis","volume":"6","author":"Montoya","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.micpath.2021.104864_bib25","doi-asserted-by":"crossref","DOI":"10.4110\/in.2020.20.e12","article-title":"Vitamin D-cathelicidin axis: at the crossroads between protective immunity and pathological inflammation during infection","volume":"20","author":"Chung","year":"2020","journal-title":"Immune Netw"},{"key":"10.1016\/j.micpath.2021.104864_bib26","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.chom.2009.08.004","article-title":"Vitamin D3 induces autophagy in human monocytes\/macrophages via cathelicidin","volume":"6","author":"Yuk","year":"2009","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.micpath.2021.104864_bib27","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.micinf.2011.10.006","article-title":"The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use","volume":"14","author":"Perera","year":"2012","journal-title":"Microb. Infect."},{"key":"10.1016\/j.micpath.2021.104864_bib28","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1590\/S0074-02762010000700005","article-title":"Interleukin-15 augments oxidative metabolism and fungicidal activity of human monocytes against Paracoccidioides brasiliensis","volume":"105","author":"Bannwart","year":"2010","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.micpath.2021.104864_bib29","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.cyto.2007.10.011","article-title":"Interleukin-15 increases Paracoccidioides brasiliensis killing by human neutrophils","volume":"41","author":"Tavian","year":"2008","journal-title":"Cytokine"},{"key":"10.1016\/j.micpath.2021.104864_bib30","doi-asserted-by":"crossref","first-page":"3714","DOI":"10.1128\/IAI.73.6.3714-3724.2005","article-title":"Expression of genes encoding innate host defense molecules in normal human monocytes in response to Candida albicans","volume":"73","author":"Kim","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2021.104864_bib31","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1128\/IAI.66.6.2640-2647.1998","article-title":"Interleukin-15 activates proinflammatory and antimicrobial functions in polymorphonuclear cells","volume":"66","author":"Musso","year":"1998","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2021.104864_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.parint.2020.102097","article-title":"IL-15 enhances the capacity of primary human macrophages to control Leishmania braziliensis infection by IL-32\/vitamin D dependent and independent pathways","volume":"76","author":"Silva","year":"2020","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.micpath.2021.104864_bib33","first-page":"S144","article-title":"The role of IL-32 in the innate host response against Candida albicans","volume":"56","author":"HHM Jaeger","year":"2018","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micpath.2021.104864_bib34","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0035-9203(98)90744-1","article-title":"Hypercalcaemia and paracoccidioidomycosis","volume":"92","author":"Silva","year":"1998","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.micpath.2021.104864_bib35","doi-asserted-by":"crossref","DOI":"10.1186\/1752-1947-2-262","article-title":"Hypercalcemia in a patient with disseminated paracoccidioidomycosis: a case report","volume":"2","author":"Almeida","year":"2008","journal-title":"J. Med. Case Rep."},{"key":"10.1016\/j.micpath.2021.104864_bib36","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2180-7-29","article-title":"The transcriptome analysis of early morphogenesis in Paracoccidioides brasiliensis mycelium reveals novel and induced genes potentially associated to the dimorphic process","volume":"7","author":"Bastos","year":"2007","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micpath.2021.104864_bib37","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.micpath.2021.104864_bib38","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1016\/j.ijrobp.2009.04.017","article-title":"Interleukin-32 positively regulates radiation-induced vascular inflammation","volume":"74","author":"Kobayashi","year":"2009","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.micpath.2021.104864_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2010.01.016","article-title":"IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic dermatitis","volume":"125","author":"Meyer","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.micpath.2021.104864_bib40","doi-asserted-by":"crossref","DOI":"10.1186\/1465-9921-13-19","article-title":"Oxidative stress induced Interleukin-32 mRNA expression in human bronchial epithelial cells","volume":"13","author":"Kudo","year":"2012","journal-title":"Respir. Res."},{"key":"10.1016\/j.micpath.2021.104864_bib41","doi-asserted-by":"crossref","DOI":"10.1186\/1743-422X-10-51","article-title":"The expression of interleukin-32 is activated by human cytomegalovirus infection and down regulated by hcmv-miR-UL112-1","volume":"10","author":"Huang","year":"2013","journal-title":"Virol. J."},{"key":"10.1016\/j.micpath.2021.104864_bib42","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/JLB.4AB0219-071R","article-title":"IL-32 and its splice variants are associated with protection against Mycobacterium tuberculosis infection and skewing of Th1\/Th17 cytokines","volume":"107","author":"Koeken","year":"2020","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.micpath.2021.104864_bib43","first-page":"207","article-title":"Interleukin-32 isoforms: expression, interaction with interferon-regulated genes and clinical significance in chronically HIV-1-infected patients","volume":"203","author":"Monteleone","year":"2014","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.micpath.2021.104864_bib44","doi-asserted-by":"crossref","DOI":"10.1038\/srep22902","article-title":"Proinflammatory isoforms of IL-32 as novel and robust biomarkers for control failure in HIV-infected slow progressors","volume":"6","author":"El-Far","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2021.104864_bib45","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/JLB.4AB0219-071R","article-title":"IL-32 and its splice variants are associated with protection against Mycobacterium tuberculosis infection and skewing of Th1\/Th17 cytokines","volume":"107","author":"Koeken","year":"2020","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.micpath.2021.104864_bib46","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1080\/13693780500536885","article-title":"TNF-\u03b1 activates human monocytes for Paracoccidioides brasiliensis killing by an H2O2-dependent mechanism","volume":"44","author":"Carmo","year":"2006","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micpath.2021.104864_bib47","doi-asserted-by":"crossref","DOI":"10.1186\/ar2074","article-title":"Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases","volume":"8","author":"Shoda","year":"2006","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.micpath.2021.104864_bib48","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.4049\/jimmunol.1601477","article-title":"Dendritic cell\u2013derived IL-32\u03b1: a novel inhibitory cytokine of NK cell function","volume":"199","author":"Gorvel","year":"2017","journal-title":"J. Immunol."},{"key":"10.1016\/j.micpath.2021.104864_bib49","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/QAI.0000000000002185","article-title":"Upregulation of IL-32 isoforms in virologically suppressed HIV-infected individuals: potential role in persistent inflammation and transcription from stable HIV-1 reservoirs","volume":"82","author":"Zaidan","year":"2019","journal-title":"J. Acquir. Immune Defic. Syndr."},{"key":"10.1016\/j.micpath.2021.104864_bib50","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1073\/pnas.0609848104","article-title":"Histoplasma capsulatum \u03b1-(1,3)-glucan blocks innate immune recognition by the \u03b2-glucan receptor","volume":"104","author":"Rappleye","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.micpath.2021.104864_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0050201","article-title":"Expression of Paracoccidioides brasiliensis AMY1 in a Histoplasma capsulatum amy1 mutant, relates an \u03b1-(1,4)-amylase to cell wall \u03b1-(1,3)-glucan synthesis","volume":"7","author":"Camacho","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/j.micpath.2021.104864_bib52","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1093\/infdis\/jiu136","article-title":"Dectin-1 induces M1 macrophages and prominent expansion of CD8 +IL-17+ cells in pulmonary paracoccidioidomycosis","volume":"210","author":"Loures","year":"2014","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micpath.2021.104864_bib53","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/myc.13007","article-title":"Evaluation of (1 \u2192 3)\u2010\u03b2\u2010D\u2010glucan assay for diagnosing paracoccidioidomycosis","volume":"63","author":"Melo","year":"2020","journal-title":"Mycoses"},{"key":"10.1016\/j.micpath.2021.104864_bib54","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1086\/515381","article-title":"Interleukin-15 induces antimicrobial activity after release by Cryptococcus neoformans-stimulated monocytes","volume":"178","author":"Mody","year":"1998","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.micpath.2021.104864_bib55","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1046\/j.1365-2567.2003.01659.x","article-title":"Host's innate immune response to fungal and bacterial agents in vitro: up-regulation of interleukin-15 gene expression resulting in enhanced natural killer cell activity","volume":"109","author":"Tran","year":"2003","journal-title":"Immunology"},{"key":"10.1016\/j.micpath.2021.104864_bib56","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1128\/IAI.66.1.145-150.1998","article-title":"Interleukin-15 augments superoxide production and microbicidal activity of human monocytes against Candida albicans","volume":"66","author":"V\u00e1zquez","year":"1998","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2021.104864_bib57","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1046\/j.1365-2567.2001.01179.x","article-title":"Modulatory effect of prostaglandins on human monocyte activation for killing of high- and low-virulence strains of Paracoccidioides brasiliensis","volume":"102","author":"Soares","year":"2001","journal-title":"Immunology"},{"key":"10.1016\/j.micpath.2021.104864_bib58","doi-asserted-by":"crossref","first-page":"726","DOI":"10.3109\/13693786.2012.676740","article-title":"Inhibitory effect of PGE2 on the killing of Paracoccidioides brasiliensis by human monocytes can be reversed by cellular activation with cytokines","volume":"50","author":"Bordon-Graciani","year":"2012","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micpath.2021.104864_bib59","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1080\/13693780802244204","article-title":"Interleukin-6 treatment enhances human monocyte permissiveness for Paracoccidioides brasiliensis growth by modulating cytokine production","volume":"47","author":"Siqueira","year":"2009","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micpath.2021.104864_bib60","doi-asserted-by":"crossref","first-page":"7115","DOI":"10.4049\/jimmunol.181.10.7115","article-title":"IL-15 links TLR2\/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway","volume":"181","author":"Krutzik","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.micpath.2021.104864_bib61","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00000441-199508000-00007","article-title":"Vitamin D-mediated hypercalcemia in fungal infections","volume":"310","author":"Spindel","year":"1995","journal-title":"Am. J. Med. Sci."},{"key":"10.1016\/j.micpath.2021.104864_bib62","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/00000441-199912000-00010","article-title":"Hypercalcemia associated with infection by Cryptococcus neoformans and Coccidioides immitis","volume":"318","author":"Ali","year":"1999","journal-title":"Am. J. Med. Sci."},{"key":"10.1016\/j.micpath.2021.104864_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.parint.2020.102097","article-title":"IL-15 enhances the capacity of primary human macrophages to control Leishmania braziliensis infection by IL-32\/vitamin D dependent and independent pathways","volume":"76","author":"Silva","year":"2020","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.micpath.2021.104864_bib64","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0239799","article-title":"Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng\/mL reduced risk for adverse clinical outcomes in patients with COVID-19 infection","volume":"15","author":"Maghbooli","year":"2020","journal-title":"PloS One"},{"key":"10.1016\/j.micpath.2021.104864_bib65","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.clinthera.2017.04.004","article-title":"Vitamin D status and the host resistance to infections: what it is currently (not) understood","volume":"39","author":"Lang","year":"2017","journal-title":"Clin. Therapeut."},{"key":"10.1016\/j.micpath.2021.104864_bib66","article-title":"Anti-inflammatory and antimicrobial actions of vitamin D in combating TB\/HIV","volume":"Cairo","author":"Coussens","year":"2014","journal-title":"Sci. Tech. Rep."},{"key":"10.1016\/j.micpath.2021.104864_bib67","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1093\/mmy\/myy120","article-title":"Paracoccidioidomycosis: characterization of subpopulations of macrophages and cytokines in human mucosal lesions","volume":"57","author":"Pagliari","year":"2019","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micpath.2021.104864_bib68","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/00000372-200304000-00003","article-title":"Dendritic cells and pattern of cytokines in paracoccidioidomycosis skin lesions","volume":"25","author":"Pagliari","year":"2003","journal-title":"Am. J. Dermatopathol."},{"key":"10.1016\/j.micpath.2021.104864_bib69","doi-asserted-by":"crossref","first-page":"6848","DOI":"10.4049\/jimmunol.1003996","article-title":"IL-32\u03b3 induces the maturation of dendritic cells with Th1- and Th17-polarizing ability through enhanced IL-12 and IL-6 production","volume":"186","author":"Jung","year":"2011","journal-title":"J. Immunol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401021001364?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401021001364?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:48:28Z","timestamp":1760111308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401021001364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":69,"alternative-id":["S0882401021001364"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2021.104864","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Paracoccidioides brasiliensis induces IL-32 and is controlled by IL-15\/IL-32\/vitamin D pathway in vitro","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2021.104864","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104864"}}