{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T19:05:55Z","timestamp":1787857555861,"version":"build-2784847793"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.micpath.2022.105505","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T11:58:05Z","timestamp":1648209485000},"page":"105505","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Benefits and costs of immune memory in Rhodnius prolixus against Trypanosoma cruzi"],"prefix":"10.1016","volume":"165","author":[{"given":"S.P.","family":"Carmona-Pe\u00f1a","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.C.","family":"V\u00e1zquez-Chagoy\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.P.","family":"Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.A.","family":"Genta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9231-0641","authenticated-orcid":false,"given":"J.","family":"Contreras-Gardu\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2022.105505_bib1","first-page":"104285","article-title":"Innate immune memory in invertebrates: concept and potential mechanisms","author":"Lanz-Mendoza","year":"2021","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.micpath.2022.105505_bib2","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/een.12300","article-title":"Insect immune priming: ecology and experimental evidences","volume":"41","author":"Contreras-Gardu\u00f1o","year":"2016","journal-title":"Ecol. Entomol."},{"key":"10.1016\/j.micpath.2022.105505_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00114-019-1657-2","article-title":"The costs of the immune memory within generations","volume":"106","author":"Contreras-Gardu\u00f1o","year":"2019","journal-title":"Sci. Nat."},{"key":"10.1016\/j.micpath.2022.105505_bib4","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.cois.2020.10.005","article-title":"Interorgan communication in the control of metamorphosis","volume":"43","author":"Malita","year":"2021","journal-title":"Curr. Opin. Insect Sci."},{"key":"10.1016\/j.micpath.2022.105505_bib5","doi-asserted-by":"crossref","first-page":"106108","DOI":"10.1016\/j.actatropica.2021.106108","article-title":"The innate immune response of triatomines against Trypanosoma cruzi and Trypanosoma rangeli with an unresolved question: do triatomines have immune memory?","volume":"224","author":"Carmona-Pe\u00f1a","year":"2021","journal-title":"Acta Trop."},{"key":"10.1016\/j.micpath.2022.105505_bib6","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1093\/jmedent\/9.4.351","article-title":"Vital statistics of Triatominae (Hemiptera: reduviidae) under laboratory conditions","volume":"9","author":"Rabinovich","year":"1972","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.micpath.2022.105505_bib7","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/S0022-1910(03)00133-1","article-title":"Suppression of the prophenoloxidase system in Rhodnius prolixus orally infected with Trypanosoma rangeli","volume":"49","author":"Gomes","year":"2003","journal-title":"J. Insect Physiol."},{"key":"10.1016\/j.micpath.2022.105505_bib8","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1006\/jipa.1995.1040","article-title":"Trypanosoma cruzi and Trypanosoma rangeli: interplay with hemolymph components of Rhodnius prolixus","volume":"65","author":"Mello","year":"1995","journal-title":"J. Invertebr. Pathol."},{"issue":"19","key":"10.1016\/j.micpath.2022.105505_bib9","doi-asserted-by":"crossref","first-page":"3855","DOI":"10.1016\/j.vaccine.2007.01.114","article-title":"Vaccination with Trypanosoma rangeli reduces the infectiousness of dogs experimentally infected with Trypanosoma cruzi","volume":"25","author":"Basso","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.micpath.2022.105505_bib10","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/ni1219","article-title":"Invertebrate immunity and the limits of mechanistic immunology","volume":"6","author":"Little","year":"2005","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.micpath.2022.105505_bib11","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1006\/expr.1996.0015","article-title":"Differential in vitro and in vivo behavior of three strains of Trypanosoma cruzi in the gut and hemolymph of Rhodnius prolixus","volume":"82","author":"Mello","year":"1996","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.micpath.2022.105505_bib12","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/425037a","article-title":"Evidence for memory in invertebrate immunity","volume":"425","author":"Kurtz","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.micpath.2022.105505_bib13","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1098\/rspb.2008.1157","article-title":"Strain-specific priming of resistance in the red flour beetle, Tribolium castaneum","volume":"276","author":"Roth","year":"2009","journal-title":"Proc. Royal Soc., B."},{"key":"10.1016\/j.micpath.2022.105505_bib14","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.actatropica.2008.10.001","article-title":"Triatominae\u2013Trypanosoma cruzi\/T. rangeli: vector\u2013parasite interactions","volume":"110","author":"Vallejo","year":"2009","journal-title":"Acta Trop."},{"key":"10.1016\/j.micpath.2022.105505_bib15","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.micpath.2018.03.063","article-title":"The occurrence of immune priming can be species-specific in entomopathogens","volume":"118","author":"Medina-G\u00f3mez","year":"2018","journal-title":"Microb. Pathog."},{"issue":"5","key":"10.1016\/j.micpath.2022.105505_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001050","article-title":"Testing the efficacy of a multi-component DNA-prime\/DNA-boost vaccine against Trypanosoma cruzi infection in dogs","volume":"5","author":"Aparicio-Burgos","year":"2011","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.micpath.2022.105505_bib17","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1006\/expr.1996.0015","article-title":"Differential in vitro and in vivo behavior of three strains of Trypanosoma cruzi in the gut and hemolymph of Rhodnius prolixus","volume":"82","author":"Mello","year":"1996","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.micpath.2022.105505_bib18","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2307\/3546608","article-title":"Developmental instability as a bet-hedging strategy","author":"Simons","year":"1997","journal-title":"Oikos"},{"key":"10.1016\/j.micpath.2022.105505_bib19","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/jvec.12132","article-title":"Reproductive and developmental costs of deltamethrin resistance in the Chagas disease vector Triatoma infestans","volume":"40","author":"Germano","year":"2015","journal-title":"J. Vector Ecol."},{"key":"10.1016\/j.micpath.2022.105505_bib20","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1080\/00034983.2000.11813586","article-title":"Effects of Triatoma virus (TrV) on the fecundity and moulting of Triatoma infestans (Hemiptera: reduviidae)","volume":"94","author":"Rozas-Dennis","year":"2000","journal-title":"Ann. Trop. Med. Parasitol."},{"issue":"5","key":"10.1016\/j.micpath.2022.105505_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0000691","article-title":"Adaptive developmental delay in Chagas disease vectors: an evolutionary ecology approach","volume":"4","author":"Menu","year":"2010","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.micpath.2022.105505_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/eea.12522","article-title":"Development time and fitness: is there an adaptive development delay in the Rhodnius prolixus fifth nymphal stage?","volume":"163","author":"Aldana","year":"2017","journal-title":"Entomol. Exp. Appl."},{"key":"10.1016\/j.micpath.2022.105505_bib23","first-page":"200","article-title":"The immune role of the arthropod exoskeleton. Invertebrate","volume":"9","author":"Moret","year":"2012","journal-title":"Surv. J."},{"key":"10.1016\/j.micpath.2022.105505_bib24","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1111\/j.1420-9101.2008.01584.x","article-title":"The stimulation of immune defence accelerates development in the red flour beetle (Tribolium castaneum)","volume":"21","author":"Roth","year":"2008","journal-title":"J. Evol. Biol."},{"key":"10.1016\/j.micpath.2022.105505_bib25","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1111\/jeb.13138","article-title":"Recovery and immune priming modulate the evolutionary trajectory of infection\u2010induced reproductive strategies","volume":"30","author":"Luu","year":"2017","journal-title":"J. Evol. Biol."},{"key":"10.1016\/j.micpath.2022.105505_bib26","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3389\/fevo.2021.651683","article-title":"Morphology, life cycle, environmental factors and fitness-a machine learning analysis in kissing bugs (Hemiptera, Reduviidae, Triatominae)","volume":"9","author":"Rabinovich","year":"2021","journal-title":"Front. Ecol. Evol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401022001188?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401022001188?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:42:23Z","timestamp":1760110943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401022001188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":26,"alternative-id":["S0882401022001188"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2022.105505","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Benefits and costs of immune memory in Rhodnius prolixus against Trypanosoma cruzi","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2022.105505","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105505"}}