{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T02:05:39Z","timestamp":1771293939200,"version":"3.50.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013804","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81301378"],"award-info":[{"award-number":["81301378"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172289"],"award-info":[{"award-number":["82172289"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["17ykpy40"],"award-info":[{"award-number":["17ykpy40"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.micpath.2023.106169","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T00:40:02Z","timestamp":1685407202000},"page":"106169","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["NLRP3 inflammasome activation contributes to fungal clearance and lung injury during Talaromyces marneffei infection"],"prefix":"10.1016","volume":"181","author":[{"given":"Sha","family":"Lu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinquan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qianling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liyan","family":"Xi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.micpath.2023.106169_bib1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/s11046-019-00410-2","article-title":"Talaromycosis (Penicilliosis) due to Talaromyces (Penicillium) marneffei: insights into the clinical trends of a major fungal disease 60 Years after the discovery of the pathogen","volume":"184","author":"Cao","year":"2019","journal-title":"Mycopathologia"},{"key":"10.1016\/j.micpath.2023.106169_bib2","series-title":"Conference of Retrovirus and Opportunistic Infections","article-title":"The global distribution, drivers, and burden of talaromycosis 1964-2018","author":"WXTN","year":"2020"},{"key":"10.1016\/j.micpath.2023.106169_bib3","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.micpath.2016.01.026","article-title":"Activation of ERK1\/2 and TNF-alpha production are regulated by calcium\/calmodulin signaling pathway during Penicillium marneffei infection within human macrophages","volume":"93","author":"Chen","year":"2016","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2023.106169_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2019.103594","article-title":"Interplay of interferon-gamma and macrophage polarization during Talaromyces marneffei infection","volume":"134","author":"Lu","year":"2019","journal-title":"Microb. Pathog."},{"issue":"6","key":"10.1016\/j.micpath.2023.106169_bib5","doi-asserted-by":"crossref","first-page":"ofz205","DOI":"10.1093\/ofid\/ofz205","article-title":"Innate immunity acts as the major regulator in Talaromyces marneffei coinfected AIDS patients: cytokine profile surveillance during initial 6-month antifungal therapy","volume":"6","author":"Dong","year":"2019","journal-title":"Open Forum Infect. Dis."},{"issue":"10","key":"10.1016\/j.micpath.2023.106169_bib6","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.micinf.2014.08.013","article-title":"Acapsular Cryptococcus neoformans activates the NLRP3 inflammasome","volume":"16","author":"Guo","year":"2014","journal-title":"Microb. Infect."},{"issue":"2","key":"10.1016\/j.micpath.2023.106169_bib7","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.chom.2015.07.004","article-title":"Pathogenic NLRP3 inflammasome activity during Candida infection is negatively regulated by IL-22 via activation of NLRC4 and IL-1Ra","volume":"18","author":"Borghi","year":"2015","journal-title":"Cell Host Microbe"},{"issue":"3","key":"10.1016\/j.micpath.2023.106169_bib8","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.chom.2015.01.006","article-title":"Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection","volume":"17","author":"Karki","year":"2015","journal-title":"Cell Host Microbe"},{"issue":"2","key":"10.1016\/j.micpath.2023.106169_bib9","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/imm.12719","article-title":"The NLRP3 inflammasome contributes to host protection during Sporothrix schenckii infection","volume":"151","author":"Goncalves","year":"2017","journal-title":"Immunology"},{"issue":"2","key":"10.1016\/j.micpath.2023.106169_bib10","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/s41564-018-0298-0","article-title":"Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection","volume":"4","author":"Briard","year":"2019","journal-title":"Nat Microbiol"},{"issue":"1","key":"10.1016\/j.micpath.2023.106169_bib11","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1080\/21505594.2022.2080904","article-title":"Talaromyces marneffei activates the AIM2-caspase-1\/-4-GSDMD axis to induce pyroptosis in hepatocytes","volume":"13","author":"Wang","year":"2022","journal-title":"Virulence"},{"issue":"7507","key":"10.1016\/j.micpath.2023.106169_bib12","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/nature13489","article-title":"Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk","volume":"511","author":"Mayer-Barber","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.micpath.2023.106169_bib13","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.molimm.2017.01.023","article-title":"Regulation and functions of NLRP3 inflammasome during influenza virus infection","volume":"86","author":"Kuriakose","year":"2017","journal-title":"Mol. Immunol."},{"issue":"8","key":"10.1016\/j.micpath.2023.106169_bib14","doi-asserted-by":"crossref","DOI":"10.3390\/cells10081932","article-title":"A fragile balance: does neutrophil extracellular trap formation drive pulmonary disease progression?","volume":"10","author":"Block","year":"2021","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.micpath.2023.106169_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.imbio.2019.11.002","article-title":"Neutrophil extracellular traps impair fungal clearance in a mouse model of invasive pulmonary aspergillosis","volume":"225","author":"Alflen","year":"2020","journal-title":"Immunobiology"},{"issue":"6","key":"10.1016\/j.micpath.2023.106169_bib16","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20200652","article-title":"Targeting potential drivers of COVID-19: neutrophil extracellular traps","volume":"217","author":"Barnes","year":"2020","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micpath.2023.106169_bib17","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.semcdb.2018.03.020","article-title":"Neutrophil extracellular traps in fungal infection","volume":"89","author":"Urban","year":"2019","journal-title":"Semin. Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.micpath.2023.106169_bib18","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/s41392-021-00650-z","article-title":"Inflammasomes as therapeutic targets in human diseases","volume":"6","author":"Li","year":"2021","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"1","key":"10.1016\/j.micpath.2023.106169_bib19","first-page":"37","article-title":"Effect of Penicillium marneffei on TLR-2, TLR-4, and Dectin-1 expression and TNF-alpha production in macrophage","volume":"28","author":"Zhao","year":"2008","journal-title":"Nan fang yi ke da xue xue bao= Journal of Southern Medical University"},{"key":"10.1016\/j.micpath.2023.106169_bib20","doi-asserted-by":"crossref","first-page":"911","DOI":"10.2147\/IDR.S237401","article-title":"Murine macrophage requires CD11b to recognize Talaromyces marneffei","volume":"13","author":"Hu","year":"2020","journal-title":"Infect. Drug Resist."},{"issue":"9","key":"10.1016\/j.micpath.2023.106169_bib21","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19092732","article-title":"NLRP3 inflammasome and IL-33: novel players in sterile liver inflammation","volume":"19","author":"Neumann","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2023.106169_bib22","article-title":"Common NLRP3 inflammasome inhibitors and Covid-19: divide and conquer","volume":"18","author":"Batiha","year":"2022","journal-title":"Sci Afr"},{"key":"10.1016\/j.micpath.2023.106169_bib23","volume":"vol. 2008","author":"Weischenfeldt","year":"2008"},{"issue":"10","key":"10.1016\/j.micpath.2023.106169_bib24","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1002\/emmm.201201316","article-title":"The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice","volume":"4","author":"Chowdhury","year":"2012","journal-title":"EMBO Mol. Med."},{"issue":"1\u20132","key":"10.1016\/j.micpath.2023.106169_bib25","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s11046-013-9650-3","article-title":"Development of in vitro macrophage system to evaluate phagocytosis and intracellular fate of Penicillium marneffei conidia","volume":"176","author":"Lu","year":"2013","journal-title":"Mycopathologia"},{"issue":"8","key":"10.1016\/j.micpath.2023.106169_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0042343","article-title":"Comparison of temporal and spatial dynamics of seasonal H3N2, pandemic H1N1 and highly pathogenic avian influenza H5N1 virus infections in ferrets","volume":"7","author":"van den Brand","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2023.106169_bib27","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.781280","article-title":"An intranasal OMV-based vaccine induces high mucosal and systemic protecting immunity against a SARS-CoV-2 infection","volume":"12","author":"van der Ley","year":"2021","journal-title":"Front. Immunol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401023002024?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401023002024?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T06:33:35Z","timestamp":1736404415000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401023002024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":27,"alternative-id":["S0882401023002024"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2023.106169","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NLRP3 inflammasome activation contributes to fungal clearance and lung injury during Talaromyces marneffei infection","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2023.106169","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106169"}}