{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:25:38Z","timestamp":1760145938342,"version":"build-2065373602"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.micpath.2024.106537","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T12:18:34Z","timestamp":1704802714000},"page":"106537","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Unveiling the functional significance of the 14.3.3 protein: A key player in Paracoccidioides brasiliensis biofilm formation"],"prefix":"10.1016","volume":"188","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8500-2691","authenticated-orcid":false,"given":"Janaina de C\u00e1ssia Orlandi","family":"Sardi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaqueline","family":"Derissi Braz Carlton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline Maria","family":"Marcos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Marisa","family":"Fusco Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Jos\u00e9 Soares","family":"Mendes Giannini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2024.106537_bib1","doi-asserted-by":"crossref","DOI":"10.1590\/0074-02760200592","article-title":"Gene expression of Paracoccidioides virulence factors after interaction with macrophages and fibroblastos","volume":"116","author":"Braz","year":"2021","journal-title":"Mem Inst Oswaldo Cruz, Rio de Janeiro"},{"issue":"5","key":"10.1016\/j.micpath.2024.106537_bib2","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s10482-019-01382-5","article-title":"Virulence factors of Paracoccidioides brasiliensis as therapeutic targets: a review","volume":"113","author":"Santos","year":"2020","journal-title":"Antonie Leeuwenhoek"},{"issue":"1","key":"10.1016\/j.micpath.2024.106537_bib3","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1128\/IAI.74.1.382-389.2006","article-title":"Glyceraldehyde-3-phosphate dehydrogenase of Paracoccidioides brasiliensis is a cell surface protein involved in fungal adhesion to extracellular matrix proteins and interaction with cells","volume":"74","author":"Barbosa","year":"2006","journal-title":"Infect. Immun."},{"issue":"8","key":"10.1016\/j.micpath.2024.106537_bib4","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1111\/j.1567-1364.2007.00292.x","article-title":"Analysis of the Paracoccidioides brasiliensis triosephosphate isomerase suggests the potential for adhesin function","volume":"7","author":"Pereira","year":"2007","journal-title":"FEMS Yeast Res."},{"issue":"Pt 6","key":"10.1016\/j.micpath.2024.106537_bib5","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1099\/jmm.0.003830-0","article-title":"Enolase from Paracoccidioides brasiliensis: isolation and identification as a fibronectin-binding protein","volume":"58","author":"Donofrio","year":"2009","journal-title":"J. Med. Microbiol."},{"issue":"9","key":"10.1016\/j.micpath.2024.106537_bib6","doi-asserted-by":"crossref","first-page":"4040","DOI":"10.1128\/IAI.00221-10","article-title":"Paracoccidioides brasiliensis enolase is a surface protein that binds plasminogen and mediates interaction of yeast forms with host cells","volume":"78","author":"Nogueira","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2024.106537_bib7","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.3389\/fmicb.2015.01319","article-title":"Paracoccidioides-host interaction: an overview on recent advances in the paracoccidioidomycosis","volume":"6","author":"de Oliveira","year":"2015","journal-title":"Front. Microbiol."},{"issue":"6","key":"10.1016\/j.micpath.2024.106537_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0039463","article-title":"Lipidomic analysis of extracellular vesicles from the pathogenic phase of Paracoccidioides brasiliensis","volume":"7","author":"Vallejo","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.micpath.2024.106537_bib9","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1080\/21505594.2015.1122166","article-title":"Decreased expression of 14-3-3 in Paracoccidioides brasiliensis confirms its involvement in fungal pathogenesis","volume":"7","author":"Marcos","year":"2016","journal-title":"Virulence"},{"issue":"5\u20136","key":"10.1016\/j.micpath.2024.106537_bib10","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.micinf.2005.02.005","article-title":"Isolation and partial characterization of a 30 kDa adhesin from Paracoccidioides brasiliensis","volume":"7","author":"Andreotti","year":"2005","journal-title":"Microb. Infect."},{"issue":"7","key":"10.1016\/j.micpath.2024.106537_bib11","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1093\/mmy\/myy112","article-title":"Paracoccidioides brasiliensis 14-3-3 protein is important for virulence in a murine model","volume":"57","author":"Marcos","year":"2019","journal-title":"Med. Mycol."},{"key":"10.1016\/j.micpath.2024.106537_bib12","doi-asserted-by":"crossref","DOI":"10.1007\/s11046-011-9513-8","article-title":"Capsular material of cryptococcus neoformans: virulence and much more","author":"Vecchiarelli","year":"2012","journal-title":"Mycopathologia"},{"issue":"Pt 1","key":"10.1016\/j.micpath.2024.106537_bib13","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1099\/jmm.0.045054-0","article-title":"Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options","volume":"62","author":"Sardi","year":"2013","journal-title":"J. Med. Microbiol."},{"issue":"7\u20138","key":"10.1016\/j.micpath.2024.106537_bib14","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1007\/s11046-017-0126-8","article-title":"V ivo Paracoccidioides sp. biofilm on vascular prosthesis","volume":"182","author":"Cattana","year":"2017","journal-title":"Mycopathologia"},{"issue":"10","key":"10.1016\/j.micpath.2024.106537_bib15","doi-asserted-by":"crossref","first-page":"6350","DOI":"10.1128\/IAI.73.10.6350-6362.2005","article-title":"Specific antibody can prevent fungal biofilm formation and this effect correlates with protective efficacy","volume":"73","author":"Martinez","year":"2005","journal-title":"Infect. Immun."},{"issue":"Pt 9","key":"10.1016\/j.micpath.2024.106537_bib16","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1099\/jmm.0.47247-0","article-title":"Development of a simple model for studying the effects of antifungal agents on multicellular communities of Aspergillus fumigatus","volume":"56","author":"Mowat","year":"2007","journal-title":"J. Med. Microbiol."},{"issue":"11","key":"10.1016\/j.micpath.2024.106537_bib17","doi-asserted-by":"crossref","first-page":"4130","DOI":"10.1128\/AAC.00234-08","article-title":"Aspergillus fumigatus forms biofilms with reduced antifungal drug susceptibility on bronchial epithelial cells","volume":"52","author":"Seidler","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"issue":"3","key":"10.1016\/j.micpath.2024.106537_bib18","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.femsim.2005.05.013","article-title":"Functional genome of the human pathogenic fungus Paracoccidioides brasiliensis","volume":"45","author":"Felipe","year":"2005","journal-title":"FEMS Immunol. Med. Microbiol."},{"issue":"12\u201313","key":"10.1016\/j.micpath.2024.106537_bib19","doi-asserted-by":"crossref","first-page":"2686","DOI":"10.1016\/j.micinf.2006.07.019","article-title":"Differential gene expression by Paracoccidioides brasiliensis in host interaction conditions: representational difference analysis identifies candidate genes associated with fungal pathogenesis","volume":"8","author":"Bail\u00e3o","year":"2006","journal-title":"Microb. Infect."},{"issue":"1","key":"10.1016\/j.micpath.2024.106537_bib20","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1574-695X.2007.00277.x","article-title":"The transcriptional profile of Paracoccidioides brasiliensis yeast cells is influenced by human plasma","volume":"51","author":"Bail\u00e3o","year":"2007","journal-title":"FEMS Immunol. Med. Microbiol."},{"issue":"Pt 3","key":"10.1016\/j.micpath.2024.106537_bib21","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1099\/jmm.0.022467-0","article-title":"Differential gene expression analysis of Paracoccidioides brasiliensis during keratinocyte infection","volume":"60","author":"Peres da Silva","year":"2011","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.micpath.2024.106537_bib22","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3389\/fmicb.2017.00036","article-title":"Antifungal therapy: new advances in the understanding and treatment of mycosis","volume":"8","author":"Scorzoni","year":"2017","journal-title":"Front. Microbiol."},{"issue":"7","key":"10.1016\/j.micpath.2024.106537_bib23","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.semcdb.2011.08.008","article-title":"The 14-3-3 proteins in regulation of cellular metabolism","volume":"22","author":"Kleppe","year":"2011","journal-title":"Semin. Cell Dev. Biol."},{"issue":"2","key":"10.1016\/j.micpath.2024.106537_bib24","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s11274-019-2597-x","article-title":"14-3-3 Proteins: a window for a deeper understanding of fungal metabolism and development","volume":"35","author":"Shi","year":"2019","journal-title":"World J. Microbiol. Biotechnol."},{"issue":"6","key":"10.1016\/j.micpath.2024.106537_bib25","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1080\/08927014.2014.919282","article-title":"In vitro characterization of Trichophyton rubrum and T. mentagrophytes biofilms","volume":"30","author":"Costa-Orlandi","year":"2014","journal-title":"Biofouling"},{"issue":"6","key":"10.1016\/j.micpath.2024.106537_bib26","doi-asserted-by":"crossref","first-page":"11357","DOI":"10.3390\/molecules200611357","article-title":"Individual constituents from essential oils inhibit biofilm mass production by multi-drug resistant Staphylococcus aureus","volume":"20","author":"Espina","year":"2015","journal-title":"Molecules"},{"issue":"5","key":"10.1016\/j.micpath.2024.106537_bib27","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1089\/sur.2014.162","article-title":"The natural surfactant glycerol monolaurate significantly reduces development of Staphylococcus aureus and Enterococcus faecalis biofilms","volume":"16","author":"Hess","year":"2015","journal-title":"Surg. Infect."},{"issue":"2","key":"10.1016\/j.micpath.2024.106537_bib28","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.mimet.2007.11.010","article-title":"Comparison of multiple methods for quantification of microbial biofilms grown in microtiter plates","volume":"72","author":"Peeters","year":"2008","journal-title":"J. Microbiol. Methods"},{"key":"10.1016\/j.micpath.2024.106537_bib29","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3389\/fcimb.2014.00066","article-title":"Extracellular enolase of Candida albicans is involved in colonization of mammalian intestinal epithelium","volume":"4","author":"Silva","year":"2014","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"11","key":"10.1016\/j.micpath.2024.106537_bib30","doi-asserted-by":"crossref","first-page":"6748","DOI":"10.1128\/IAI.72.11.6748-6752.2004","article-title":"Streptococcus mutans surface alpha-enolase binds salivary mucin MG2 and human plasminogen","volume":"72","author":"Ge","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2024.106537_bib31","doi-asserted-by":"crossref","first-page":"719","DOI":"10.3389\/fmicb.2014.00719","article-title":"The multifaceted roles of metabolic enzymes in the Paracoccidioides species complex","volume":"5","author":"Marcos","year":"2014","journal-title":"Front. Microbiol."},{"issue":"4","key":"10.1016\/j.micpath.2024.106537_bib32","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1128\/iai.62.4.1465-1469.1994","article-title":"Binding of Paracoccidioides brasiliensis to laminin through surface glycoprotein gp43 leads to enhancement of fungal pathogenesis","volume":"62","author":"Vicentini","year":"1994","journal-title":"Infect. Immun."},{"issue":"8","key":"10.1016\/j.micpath.2024.106537_bib33","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/S1286-4579(00)00390-7","article-title":"Adherence and intracellular parasitism of Paracoccidioides brasiliensis in Vero cells","volume":"2","author":"Hanna","year":"2000","journal-title":"Microb. Infect."},{"key":"10.1016\/j.micpath.2024.106537_bib34","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0070-2153(05)68010-6","article-title":"Role of 14-3-3 proteins in eukaryotic signaling and development","volume":"68","author":"Darling","year":"2005","journal-title":"Curr. Top. Dev. Biol."},{"issue":"5","key":"10.1016\/j.micpath.2024.106537_bib35","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ygeno.2009.07.004","article-title":"14-3-3 Proteins: insights from genome-wide studies in yeast","volume":"94","author":"Van Heusden","year":"2009","journal-title":"Genomics"},{"issue":"7","key":"10.1016\/j.micpath.2024.106537_bib36","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.semcdb.2011.09.001","article-title":"Structural basis of 14-3-3 protein functions","volume":"22","author":"Obsil","year":"2011","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.micpath.2024.106537_bib37","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1186\/s12866-015-0586-2","article-title":"Functional analysis of Paracoccidioides brasiliensis 14-3-3 adhesin expressed in Saccharomyces cerevisiae","volume":"15","author":"Assato","year":"2015","journal-title":"BMC Microbiol."},{"issue":"11","key":"10.1016\/j.micpath.2024.106537_bib38","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1002\/jbm.a.34221","article-title":"Gene expression during S. epidermidis biofilm formation on biomaterials","volume":"100","author":"Patel","year":"2012","journal-title":"J. Biomed. Mater. Res."},{"issue":"1","key":"10.1016\/j.micpath.2024.106537_bib39","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1167\/iovs.17-22933","article-title":"Temporal expression of genes in biofilm-forming ocular Candida albicans isolated from patients with keratitis and orbital cellulitis","volume":"59","author":"Ranjith","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"2","key":"10.1016\/j.micpath.2024.106537_bib40","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1128\/CMR.15.2.167-193.2002","article-title":"Biofilms: survival mechanisms of clinically relevant microorganisms","volume":"15","author":"Donlan","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"issue":"4","key":"10.1016\/j.micpath.2024.106537_bib41","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002585","article-title":"Fungal biofilms","volume":"8","author":"Fanning","year":"2012","journal-title":"PLoS Pathog."},{"issue":"4","key":"10.1016\/j.micpath.2024.106537_bib42","doi-asserted-by":"crossref","first-page":"340","DOI":"10.3109\/10408410903241436","article-title":"Our current understanding of fungal biofilms","volume":"35","author":"Ramage","year":"2009","journal-title":"Crit. Rev. Microbiol."},{"key":"10.1016\/j.micpath.2024.106537_bib43","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev-micro-091014-104330","article-title":"Candida albicans biofilms and human disease","volume":"69","author":"Nobile","year":"2015","journal-title":"Annu. Rev. Microbiol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024000044?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024000044?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:01:39Z","timestamp":1760112099000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401024000044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":43,"alternative-id":["S0882401024000044"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106537","relation":{},"ISSN":["0882-4010"],"issn-type":[{"type":"print","value":"0882-4010"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unveiling the functional significance of the 14.3.3 protein: A key player in Paracoccidioides brasiliensis biofilm formation","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106537","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106537"}}