{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:16:15Z","timestamp":1790007375681,"version":"4.0.1"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.micpath.2024.106689","type":"journal-article","created":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T01:46:53Z","timestamp":1715651213000},"page":"106689","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["A novel endolysin from an Enterococcus faecalis phage and application"],"prefix":"10.1016","volume":"192","author":[{"given":"Yingying","family":"Xiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuelin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunlin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1421-8049","authenticated-orcid":false,"given":"Xiuling","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.micpath.2024.106689_bib1","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1002\/j.0022-0337.2001.65.10.tb03446.x","article-title":"The microbiology of primary dental caries in humans","volume":"65","author":"Tanzer","year":"2001","journal-title":"J. Dent. Educ."},{"issue":"12","key":"10.1016\/j.micpath.2024.106689_bib2","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1016\/j.joen.2015.08.022","article-title":"Microbiomes of endodontic-periodontal lesions before and after chemomechanical preparation","volume":"41","author":"Gomes","year":"2015","journal-title":"J. Endod."},{"key":"10.1016\/j.micpath.2024.106689_bib3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/9781119272014.ch4","article-title":"Microbiology of apical periodontitis","author":"Siqueira","year":"2019","journal-title":"Essent. Endodontology: Prev. Treat. Apical Periodontitis"},{"issue":"7","key":"10.1016\/j.micpath.2024.106689_bib4","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.joen.2009.04.010","article-title":"Molecular analysis of persistent periradicular lesions and root ends reveals a diverse microbial profile","volume":"35","author":"Subramanian","year":"2009","journal-title":"J. Endod."},{"issue":"4","key":"10.1016\/j.micpath.2024.106689_bib5","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/iej.12322","article-title":"Assessment of dentinal tubule invasion capacity of Enterococcus faecalis under stress conditions ex vivo","volume":"48","author":"Ran","year":"2015","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.micpath.2024.106689_bib6","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/ijos.2012.17","article-title":"Prevalence of Enterococcus faecalis in saliva and filled root canals of teeth associated with apical periodontitis","volume":"4","author":"Wang","year":"2012","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.micpath.2024.106689_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2023.106337","article-title":"Enterococcus faecalis in secondary apical periodontitis: mechanisms of bacterial survival and disease persistence","volume":"183","author":"Elashiry","year":"2023","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2024.106689_bib8","volume":"vol. 10","author":"Li","year":"2018"},{"issue":"6","key":"10.1016\/j.micpath.2024.106689_bib9","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.2165\/11599800-000000000-00000","article-title":"Essentials for selecting antimicrobial therapy for intra-abdominal infections","volume":"72","author":"Blot","year":"2012","journal-title":"Drugs"},{"issue":"10","key":"10.1016\/j.micpath.2024.106689_bib10","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.5958\/0974-360X.2016.00363.2","article-title":"Microbiology of polymicrobial abscess","volume":"9","author":"Poornaprabha","year":"2016","journal-title":"Res. J. Pharm. Technol."},{"issue":"2","key":"10.1016\/j.micpath.2024.106689_bib11","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/1457496920984078","article-title":"Secondary peritonitis and intra-abdominal sepsis: an increasingly global disease in search of better systemic therapies","volume":"110","author":"Clements","year":"2021","journal-title":"Scand. J. Surg."},{"issue":"3","key":"10.1016\/j.micpath.2024.106689_bib12","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/0002-9610(84)90460-4","article-title":"Role of enterococcus in intraabdominal sepsis","volume":"148","author":"Dougherty","year":"1984","journal-title":"Am. J. Surg."},{"key":"10.1016\/j.micpath.2024.106689_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.fm.2019.103344","article-title":"Inhibition of biofilm formation and exopolysaccharide synthesis of Enterococcus faecalis by phenyllactic acid","volume":"86","author":"Liu","year":"2020","journal-title":"Food Microbiol."},{"key":"10.1016\/j.micpath.2024.106689_bib14","doi-asserted-by":"crossref","first-page":"653","DOI":"10.3389\/fchem.2019.00653","article-title":"Antimicrobial activity of naturally occurring phenols and derivatives against biofilm and planktonic bacteria","volume":"7","author":"Walsh","year":"2019","journal-title":"Front. Chem."},{"key":"10.1016\/j.micpath.2024.106689_bib15","first-page":"1534","article-title":"Enterococcus faecalis from food, clinical specimens, and oral sites: prevalence of virulence factors in association with biofilm formation","volume":"6","author":"Anderson","year":"2015","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2024.106689_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2021.126746","article-title":"Bacteriophage-encoded enzymes destroying bacterial cell membranes and walls, and their potential use as antimicrobial agents","volume":"248","author":"Grabowski","year":"2021","journal-title":"Microbiol. Res."},{"issue":"6","key":"10.1016\/j.micpath.2024.106689_bib17","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.mib.2013.08.008","article-title":"Phage lysis: do we have the hole story yet?","volume":"16","author":"Young","year":"2013","journal-title":"Curr. Opin. Microbiol."},{"issue":"3","key":"10.1016\/j.micpath.2024.106689_bib18","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/S0966-842X(00)01705-4","article-title":"Phages will out: strategies of host cell lysis","volume":"8","author":"Young","year":"2000","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.micpath.2024.106689_bib19","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1146\/annurev.micro.54.1.799","article-title":"Holins: the protein clocks of bacteriophage infections","volume":"54","author":"Wang","year":"2000","journal-title":"Annu. Rev. Microbiol."},{"issue":"3","key":"10.1016\/j.micpath.2024.106689_bib20","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1128\/mr.56.3.430-481.1992","article-title":"Bacteriophage lysis: mechanism and regulation","volume":"56","author":"Young","year":"1992","journal-title":"Microbiol. Rev."},{"issue":"1","key":"10.1016\/j.micpath.2024.106689_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0169180","article-title":"The phage Lysin PlySs2 decolonizes Streptococcus suis from murine intranasal mucosa","volume":"12","author":"Gilmer","year":"2017","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.micpath.2024.106689_bib22","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00457-17","article-title":"Efficient killing of planktonic and biofilm-embedded coagulase-negative staphylococci by bactericidal protein P128","volume":"61","author":"Poonacha","year":"2017","journal-title":"Antimicrob. Agents Chemother."},{"issue":"5","key":"10.1016\/j.micpath.2024.106689_bib23","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1093\/jac\/dku552","article-title":"Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection","volume":"70","author":"Schmelcher","year":"2015","journal-title":"J. Antimicrob. Chemother."},{"issue":"11","key":"10.1016\/j.micpath.2024.106689_bib24","article-title":"Characterization of Enterococcus faecalis phage IME-EF1 and its endolysin","volume":"8","author":"Zhang","year":"2013","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.micpath.2024.106689_bib25","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1139\/cjm-2019-0336","article-title":"Biological characteristics and whole-genome analysis of the Enterococcus faecalis phage PEf771","volume":"66","author":"Xiang","year":"2020","journal-title":"Can. J. Microbiol."},{"issue":"5\u20136","key":"10.1016\/j.micpath.2024.106689_bib26","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1007\/s00253-022-11810-8","article-title":"Phage therapy for refractory periapical periodontitis caused by Enterococcus faecalis in vitro and in vivo","volume":"106","author":"Xiang","year":"2022","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"4","key":"10.1016\/j.micpath.2024.106689_bib27","doi-asserted-by":"crossref","first-page":"769","DOI":"10.21037\/jgo.2018.04.07","article-title":"The gut microbiome and colorectal cancer: a review of bacterial pathogenesis","volume":"9","author":"Dahmus","year":"2018","journal-title":"J. Gastrointest. Oncol."},{"issue":"6","key":"10.1016\/j.micpath.2024.106689_bib28","doi-asserted-by":"crossref","first-page":"505","DOI":"10.4161\/gmic.26205","article-title":"The role of the gastrointestinal microbiome in Helicobacter pylori pathogenesis","volume":"4","author":"Sheh","year":"2013","journal-title":"Gut Microb."},{"issue":"8","key":"10.1016\/j.micpath.2024.106689_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0043958","article-title":"Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content","volume":"7","author":"Mishra","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.micpath.2024.106689_bib30","article-title":"Endolysin LysEF-P10 shows potential as an alternative treatment strategy for multidrug-resistant Enterococcus faecalis infections","volume":"7","author":"Cheng","year":"2017","journal-title":"Sci. Rep."},{"issue":"14","key":"10.1016\/j.micpath.2024.106689_bib31","doi-asserted-by":"crossref","first-page":"4808","DOI":"10.1128\/JB.186.14.4808-4812.2004","article-title":"Identification of a broadly active phage lytic enzyme with lethal activity against antibiotic-resistant Enterococcus faecalis and Enterococcus faecium","volume":"186","author":"Yoong","year":"2004","journal-title":"J. Bacteriol."},{"issue":"5","key":"10.1016\/j.micpath.2024.106689_bib32","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1111\/j.1365-2672.2009.04576.x","article-title":"Complete genome sequence of a newly isolated lytic bacteriophage, EFAP-1 of Enterococcus faecalis, and antibacterial activity of its endolysin EFAL-1","volume":"108","author":"Son","year":"2010","journal-title":"J. Appl. Microbiol."},{"issue":"2","key":"10.1016\/j.micpath.2024.106689_bib33","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1128\/AEM.01540-10","article-title":"Characterization of lytic enzyme open reading frame 9 (ORF9) derived from Enterococcus faecalis bacteriophage phiEF24C","volume":"77","author":"Uchiyama","year":"2011","journal-title":"Appl. Environ. Microbiol."},{"issue":"3","key":"10.1016\/j.micpath.2024.106689_bib34","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1089\/mdr.2012.0024","article-title":"Phage endolysins with broad antimicrobial activity against Enterococcus faecalis clinical strains","volume":"18","author":"Proen\u00e7a","year":"2012","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.micpath.2024.106689_bib35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.virol.2016.02.006","article-title":"Characterization of Enterococcus faecium bacteriophage IME-EFm5 and its endolysin LysEFm5","volume":"492","author":"Gong","year":"2016","journal-title":"Virology"},{"issue":"13","key":"10.1016\/j.micpath.2024.106689_bib36","doi-asserted-by":"crossref","DOI":"10.1128\/AEM.00555-19","article-title":"Bacteriophage \u03c6Ef11 ORF28 endolysin, a multifunctional lytic enzyme with properties distinct from all other identified Enterococcus faecalis phage endolysins","volume":"85","author":"Zhang","year":"2019","journal-title":"Appl. Environ. Microbiol."},{"issue":"3","key":"10.1016\/j.micpath.2024.106689_bib38","doi-asserted-by":"crossref","first-page":"426","DOI":"10.3390\/v13030426","article-title":"Comparison of Enterococcus faecalis biofilm removal efficiency among bacteriophage PBEF129, its endolysin, and cefotaxime","volume":"13","author":"Oh","year":"2021","journal-title":"Viruses"},{"issue":"10","key":"10.1016\/j.micpath.2024.106689_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e11154","article-title":"Effect of sub-inhibitory concentrations of antibiotics on biofilm formation and expression of virulence genes in penicillin-resistant, ampicillin-susceptible Enterococcus faecalis","volume":"8","author":"Caixeta Magalh\u00e3es Tib\u00farcio","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.micpath.2024.106689_bib40","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.micpath.2015.12.008","article-title":"Gentamicin induces efaA expression and biofilm formation in Enterococcus faecalis","volume":"92","author":"Kafil","year":"2016","journal-title":"Microb. Pathog."},{"issue":"24","key":"10.1016\/j.micpath.2024.106689_bib41","doi-asserted-by":"crossref","first-page":"5555","DOI":"10.1021\/jf5006269","article-title":"Genetic and biochemical evidence that recombinant Enterococcus spp. strains expressing gelatinase (GelE) produce bovine milk-derived hydrolysates with high angiotensin converting enzyme-inhibitory activity (ACE-IA)","volume":"62","author":"G\u00fatiez","year":"2014","journal-title":"J. Agric. Food Chem."},{"issue":"6","key":"10.1016\/j.micpath.2024.106689_bib42","doi-asserted-by":"crossref","first-page":"3658","DOI":"10.1128\/IAI.72.6.3658-3663.2004","article-title":"Influence of origin of isolates, especially endocarditis isolates, and various genes on biofilm formation by Enterococcus faecalis","volume":"72","author":"Mohamed","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2024.106689_bib43","doi-asserted-by":"crossref","first-page":"7489","DOI":"10.1038\/ncomms8489","article-title":"Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota","volume":"6","author":"Chang","year":"2015","journal-title":"Nat. Commun."},{"issue":"7585","key":"10.1016\/j.micpath.2024.106689_bib44","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1038\/nature16504","article-title":"Diet-induced extinctions in the gut microbiota compound over generations","volume":"529","author":"Sonnenburg","year":"2016","journal-title":"Nature"},{"issue":"18","key":"10.1016\/j.micpath.2024.106689_bib45","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27186061","article-title":"Effects of auricularia auricula polysaccharides on gut microbiota composition in type 2 diabetic mice","volume":"27","author":"Liu","year":"2022","journal-title":"Molecules"},{"issue":"7","key":"10.1016\/j.micpath.2024.106689_bib46","doi-asserted-by":"crossref","first-page":"4570","DOI":"10.1074\/jbc.M109.063743","article-title":"Catalytic role of the metal ion in the metallo-beta-lactamase GOB","volume":"285","author":"Lisa","year":"2010","journal-title":"J. Biol. Chem."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024001566?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024001566?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T05:48:54Z","timestamp":1718344134000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401024001566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":45,"alternative-id":["S0882401024001566"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106689","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel endolysin from an Enterococcus faecalis phage and application","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106689","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106689"}}