{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:24:44Z","timestamp":1791199484214,"version":"4.2.0"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003758","name":"FAPEMA","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003758","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.micpath.2024.106837","type":"journal-article","created":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T06:31:56Z","timestamp":1722666716000},"page":"106837","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Nanoemulsions of essential oils against multi-resistant microorganisms: An integrative review"],"prefix":"10.1016","volume":"195","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8884-8537","authenticated-orcid":false,"given":"Gabriel Sousa","family":"Brito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard Pereira","family":"Dutra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6562-252X","authenticated-orcid":false,"given":"Ana L\u00facia","family":"Fernandes Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana Gomes Nogueira","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelino Santos","family":"Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alexandre","family":"Holanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8191-5955","authenticated-orcid":false,"given":"Queli Cristina","family":"Fidelis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.micpath.2024.106837_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0197111","article-title":"The impact of antibiotic use on transmission of resistant bacteria in hospitals: insights from an agent-based model","volume":"13","author":"Almagor","year":"2018","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.micpath.2024.106837_bib2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0215666","article-title":"Multiple antibiotic resistance as a risk factor for mortality and prolonged hospital stay: a cohort study among neonatal intensive care patients with hospital-acquired infections caused by gram-negative bacteria in Vietnam","volume":"14","author":"Peters","year":"2019","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.micpath.2024.106837_bib3","doi-asserted-by":"crossref","first-page":"360","DOI":"10.3390\/antibiotics11030360","article-title":"Influence of sub-inhibitory dosage of cefotaxime on multidrug resistant Staphylococcus haemolyticus isolated from sick neonatal care unit","volume":"11","author":"Chakraborty","year":"2022","journal-title":"Antibiotics"},{"issue":"5","key":"10.1016\/j.micpath.2024.106837_bib4","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/s41579-021-00649-x","article-title":"Antibiotic resistance in the environment","volume":"20","author":"Larsson","year":"2022","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.micpath.2024.106837_bib5","series-title":"Antimicrobial Resistance and the United Nations Sustainable Development Cooperation Framework: Guidance for United Nations Country Teams","year":"2021"},{"key":"10.1016\/j.micpath.2024.106837_bib6","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3390\/ph15040413","article-title":"Progress report: antimicrobial drug discovery in the resistance era","volume":"15","author":"Shinu","year":"2022","journal-title":"Pharmaceuticals"},{"issue":"3","key":"10.1016\/j.micpath.2024.106837_bib7","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3390\/medicines4030058","article-title":"Antimicrobial activity of some essential oils\u2014present status and future perspectives","volume":"4","author":"Chouhan","year":"2017","journal-title":"Medicines"},{"issue":"3","key":"10.1016\/j.micpath.2024.106837_bib8","doi-asserted-by":"crossref","first-page":"327","DOI":"10.3390\/pharmaceutics13030327","article-title":"Essential oils: pharmaceutical applications and encapsulation strategies into lipid-based delivery systems","volume":"13","author":"Cimino","year":"2021","journal-title":"Pharmaceutics"},{"issue":"13","key":"10.1016\/j.micpath.2024.106837_bib9","doi-asserted-by":"crossref","first-page":"5778","DOI":"10.3390\/app11135778","article-title":"Nanoencapsulation of essential oils as natural food antimicrobial agents: an overview","volume":"11","author":"Liao","year":"2021","journal-title":"Appl. Sci."},{"key":"10.1016\/j.micpath.2024.106837_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2020.111389","article-title":"Phytochemical delivery through nanocarriers: a review","volume":"197","author":"Ahmad","year":"2021","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.micpath.2024.106837_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2024.104888","article-title":"Recent updates and feasibility of nanodrugs in the prevention and eradication of dental biofilm and its associated pathogens-A review","volume":"143","author":"Kannan","year":"2024","journal-title":"J. Dent."},{"key":"10.1016\/j.micpath.2024.106837_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2024.106568","article-title":"Treatment of dental biofilm-forming bacterium Streptococcus mutans using tannic acid-mediated gold nanoparticles","volume":"189","author":"Selvaraj","year":"2024","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2024.106837_bib13","doi-asserted-by":"crossref","first-page":"445","DOI":"10.17219\/dmp\/150728","article-title":"Antibacterial and anti-inflammatory effects of a novel herb-mediated nanocomposite mouthwash in plaque-induced gingivitis: a randomized controlled trial","volume":"60","author":"Soundarajan","year":"2023","journal-title":"Dent Med Probl"},{"issue":"5","key":"10.1016\/j.micpath.2024.106837_bib14","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1080\/14786419.2018.1493588","article-title":"Flavonoids: biological activities and therapeutic potential","volume":"34","author":"Juc\u00e1","year":"2020","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.micpath.2024.106837_bib15","article-title":"Nanoemulsions: the rising star of antiviral therapeutics and nanodelivery system\u2014current status and prospects","volume":"54","author":"Flankline","year":"2021","journal-title":"Curr. Opin. Colloid Interface Sci."},{"issue":"22","key":"10.1016\/j.micpath.2024.106837_bib16","doi-asserted-by":"crossref","DOI":"10.3390\/app112210695","article-title":"Application of polymeric nanocarriers for enhancing the bioavailability of antibiotics at the target site and overcoming antimicrobial resistance","volume":"11","author":"Le","year":"2021","journal-title":"Appl. Sci."},{"key":"10.1016\/j.micpath.2024.106837_bib17","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.3389\/fmicb.2017.02328","article-title":"A food grade pimenta leaf essential oil reduces the attachment of Salmonella enterica heidelberg (2011 ground Turkey outbreak isolate) on to Turkey skin","volume":"8","author":"Nair","year":"2017","journal-title":"Front. Microbiol."},{"issue":"5","key":"10.1016\/j.micpath.2024.106837_bib18","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1365-2648.2005.03621.x","article-title":"The integrative review: updated methodology","volume":"52","author":"Whittemore","year":"2005","journal-title":"J. Adv. Nurs."},{"issue":"1","key":"10.1016\/j.micpath.2024.106837_bib19","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan\u2014a web and mobile app for systematic reviews","volume":"5","author":"Ouzzani","year":"2016","journal-title":"Syst. Rev."},{"key":"10.1016\/j.micpath.2024.106837_bib20","unstructured":"Joanna Briggs Institute (JBI). Joanna Briggs Institute reviewers' manual: 2019 edition. https:\/\/wiki.joannabriggs.org\/display\/MANUAL\/2.6.2+Review+question."},{"key":"10.1016\/j.micpath.2024.106837_bib21","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"issue":"7","key":"10.1016\/j.micpath.2024.106837_bib22","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1007\/s13204-019-01111-4","article-title":"Cinnamon and clove oil nanoemulsions: novel therapeutic options against vancomycin intermediate susceptible Staphylococcus aureus","volume":"9","author":"Franklyne","year":"2019","journal-title":"Appl. Nanosci."},{"key":"10.1016\/j.micpath.2024.106837_bib23","article-title":"Alkaline tea tree oil nanoemulsion nebulizers for the treatment of pneumonia induced by drug-resistant Acinetobacter baumannii","volume":"79","author":"Zhang","year":"2023","journal-title":"J. Drug Deliv. Sci. Technol."},{"issue":"15","key":"10.1016\/j.micpath.2024.106837_bib24","doi-asserted-by":"crossref","first-page":"2630","DOI":"10.3390\/nano12152630","article-title":"Effect of nanoencapsulation on the antimicrobial and antibiofilm activities of Algerian Origanum glandulosum desf. Against multidrug-resistant clinical isolates","volume":"12","author":"Bouaouina","year":"2022","journal-title":"Nanomaterials"},{"key":"10.1016\/j.micpath.2024.106837_bib25","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.indcrop.2017.02.015","article-title":"Essential oil nanoemulsions of wild patchouli attenuate multi-drug resistant gram-positive, gram-negative and Candida albicans","volume":"100","author":"Adhavan","year":"2017","journal-title":"Ind. Crop. Prod."},{"issue":"11","key":"10.1016\/j.micpath.2024.106837_bib26","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.3390\/antibiotics10111300","article-title":"Essential oil and hydrophilic antibiotic Co-encapsulation in multiple lipid nanoparticles: proof of concept and in vitro activity against Pseudomonas aeruginosa","volume":"10","author":"Ben-Khalifa","year":"2021","journal-title":"Antibiotics"},{"issue":"1","key":"10.1016\/j.micpath.2024.106837_bib27","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3390\/pharmaceutics12010007","article-title":"Chemical profiles\/phytochemical screening, antimicrobial activity and O\/W NanoEmulsion formulations","volume":"12","author":"Maccelli","year":"2019","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.micpath.2024.106837_bib28","article-title":"Levofloxacin loaded clove essential oil nanoscale emulsion as an efficient system against Pseudomonas aeruginosa biofilm","volume":"68","author":"Razdan","year":"2022","journal-title":"J. Drug Deliv. Sci. Technol."},{"issue":"7","key":"10.1016\/j.micpath.2024.106837_bib29","doi-asserted-by":"crossref","first-page":"678","DOI":"10.3390\/pharmaceutics12070678","article-title":"Antimicrobial essential oil formulation: chitosan coated nanoemulsions for nose to brain delivery","volume":"12","author":"Rinaldi","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.micpath.2024.106837_bib30","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.molliq.2018.07.023","article-title":"Antibacterial and anti-biofilm activity of nanoemulsion of Thymus daenensis oil against multi-drug resistant Acinetobacter baumannii","volume":"265","author":"Moghimi","year":"2018","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.micpath.2024.106837_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.sajb.2022.11.010","article-title":"Optimization of antibacterial activity of essential oil mixture obtained from three medicinal plants: evaluation of synergism with conventional antibiotics and nanoemulsion effectiveness","volume":"151","author":"Soulaimani","year":"2022","journal-title":"South Afr. J. Bot."},{"key":"10.1016\/j.micpath.2024.106837_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105530","article-title":"Characterization of Turpentine nanoemulsion and assessment of its antibiofilm potential against methicillin-resistant Staphylococcus aureus","volume":"166","author":"Merghni","year":"2022","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2024.106837_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.hermed.2021.100452","article-title":"In vitro antifungal activity of Thymus vulgaris essential oil nanoemulsion","volume":"28","author":"Moazeni","year":"2021","journal-title":"J. Herb. Med."},{"key":"10.1016\/j.micpath.2024.106837_bib34","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1055\/s-0030-1250027","article-title":"Potential of Cameroonian plants and derived products against microbial infections: a review","volume":"76","author":"Kuete","year":"2010","journal-title":"Planta Med."},{"key":"10.1016\/j.micpath.2024.106837_bib35","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.2217\/fmb-2020-0301","article-title":"Quorum-sensing regulation of virulence factors in bacterial biofilm","volume":"16","author":"Warrier","year":"2021","journal-title":"Future Microbiol."},{"key":"10.1016\/j.micpath.2024.106837_bib36","doi-asserted-by":"crossref","first-page":"D912","DOI":"10.1093\/nar\/gkab1107","article-title":"VFDB 2022: a genral classification scheme for bacterial virulence factors","volume":"50","author":"Liu","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"33","key":"10.1016\/j.micpath.2024.106837_bib37","doi-asserted-by":"crossref","first-page":"12567","DOI":"10.1080\/10408398.2022.2103089","article-title":"Can droplet size influence antibacterial activity in ultrasound-prepared essential oil nanoemulsions?","volume":"63","author":"da Silva","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.micpath.2024.106837_bib38","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.lwt.2018.04.015","article-title":"Chemical composition and antibacterial activity of Eugenia brejoensis essential oil nanoemulsions against Pseudomonas fluorescens","volume":"93","author":"Mendes","year":"2018","journal-title":"Lebensm. Wiss. Technol."},{"issue":"2","key":"10.1016\/j.micpath.2024.106837_bib39","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3390\/jof7020079","article-title":"Candida albicans - the virulence factors and clinical manifestations of infection","volume":"7","author":"Talapko","year":"2021","journal-title":"Journal of Fungi"},{"key":"10.1016\/j.micpath.2024.106837_bib40","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.3390\/biomedicines11041063","article-title":"Antifungal drug resistance: an emergent health threat","volume":"11","author":"Vitiello","year":"2023","journal-title":"Biomedicines"},{"key":"10.1016\/j.micpath.2024.106837_bib41","article-title":"Exploring the efficacy of antibiotic-essential oil combinations: implications for combating antimicrobial resistance","volume":"24","author":"Janotto","year":"2023","journal-title":"Bioresour. Technol. Rep."},{"key":"10.1016\/j.micpath.2024.106837_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2023.117187","article-title":"Tackling multidrug-resistant Staphylococcus aureus by natural products and their analogues acting as NorA efflux pump inhibitors","volume":"80","author":"Kumar","year":"2023","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.micpath.2024.106837_bib43","doi-asserted-by":"crossref","first-page":"5145","DOI":"10.1016\/j.sjbs.2021.05.033","article-title":"Using essential oils to overcome bacterial biofilm formation and their antimicrobial resistance","volume":"28","author":"El-Tarabily","year":"2021","journal-title":"Saudi J. Biol. Sci."},{"issue":"3","key":"10.1016\/j.micpath.2024.106837_bib44","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3390\/medicines4030058","article-title":"Antimicrobial activity of some essential oils\u2014present status and future perspectives","volume":"4","author":"Chouhan","year":"2017","journal-title":"Medicines"},{"key":"10.1016\/j.micpath.2024.106837_bib45","series-title":"Science against Microbial Pathogens: Communicating Current Research and Technological Advances","article-title":"The mode of antibacterial action of essential oils","author":"Faleiro","year":"2011"},{"key":"10.1016\/j.micpath.2024.106837_bib46","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.foodcont.2015.05.032","article-title":"Antibacterial activity and mechanism of cinnamon essential oil against Escherichia coli and Staphylococcus aureus","volume":"59","author":"Zhang","year":"2016","journal-title":"Food Control"},{"key":"10.1016\/j.micpath.2024.106837_bib47","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s12257-022-0055-3","article-title":"Nanoemulsion as an effective inhibitor of biofilm-forming bacterial associated drug resistance: an insight into COVID based nosocomial infections","volume":"27","author":"Raj","year":"2022","journal-title":"Biotechnol. Bioproc. Eng."},{"key":"10.1016\/j.micpath.2024.106837_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.751062","article-title":"Essential oil nanoemulsion as eco-friendly and safe preservative: bioefficacy against microbial food deterioration and toxin secretion, mode of action, and future opportunities","volume":"12","author":"Maurya","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2024.106837_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.fm.2023.104459","article-title":"Lemon essential oil nanoemulsions: potential natural inhibitors against Escherichia coli","volume":"119","author":"Xiao","year":"2024","journal-title":"Food Microbiol."},{"issue":"15","key":"10.1016\/j.micpath.2024.106837_bib50","doi-asserted-by":"crossref","first-page":"5320","DOI":"10.3390\/ijms21155320","article-title":"Microbial virulence factors","volume":"21","author":"Leit\u00e3o","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2024.106837_bib51","doi-asserted-by":"crossref","first-page":"9162","DOI":"10.1021\/acs.chemrev.6b00184","article-title":"Plant natural products targeting bacterial virulence factors","volume":"116","author":"Silva","year":"2016","journal-title":"Chem. Rev."},{"issue":"12","key":"10.1016\/j.micpath.2024.106837_bib52","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/j.chembiol.2012.10.022","article-title":"Molecular basis of in vivo biofilm formation by bacterial pathogens","volume":"19","author":"Joo","year":"2012","journal-title":"Chem. Biol."},{"issue":"5","key":"10.1016\/j.micpath.2024.106837_bib53","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.3390\/ijms18051077","article-title":"Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype","volume":"18","author":"Di Domenico","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2024.106837_bib54","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a010306","article-title":"Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era","volume":"3","author":"Kostakioti","year":"2013","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"8","key":"10.1016\/j.micpath.2024.106837_bib55","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1007\/s10295-019-02181-7","article-title":"Quorum sensing inhibition as a promising method to control biofilm growth in metalworking fluids","volume":"46","author":"\u00d6zcan","year":"2019","journal-title":"J. Ind. Microbiol. Biotechnol."},{"key":"10.1016\/j.micpath.2024.106837_bib56","doi-asserted-by":"crossref","first-page":"5267","DOI":"10.1080\/10408398.2021.1883548","article-title":"The impact of essential oils on antibiotic use in animal production regarding antimicrobial resistance \u2013 a review","volume":"62","author":"Evangelista","year":"2022","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.micpath.2024.106837_bib57","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1039\/D0BM00558D","article-title":"The regulation of nanomaterials and nanomedicines for clinical application: current and future perspectives","volume":"8","author":"Foulkes","year":"2020","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.micpath.2024.106837_bib58","series-title":"Chapter 19 - Safety of Nanoemulsions and Their Regulatory Status","first-page":"613","author":"Wani","year":"2018"},{"key":"10.1016\/j.micpath.2024.106837_bib59","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.fct.2017.04.019","article-title":"Evaluation of garlic oil in nano-emulsified form: optimization and its efficacy in high-fat diet induced dyslipidemia in Wistar rats","volume":"105","author":"Ragavan","year":"2017","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.micpath.2024.106837_bib60","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.vetpar.2015.07.019","article-title":"In vitro effects of Eucalyptus staigeriana nanoemulsion on Haemonchus contortus and toxicity in rodents","volume":"212","author":"Ribeiro","year":"2015","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.micpath.2024.106837_bib61","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.fct.2017.09.031","article-title":"Changes in hepatic gene expression and serum metabolites after oral administration of overdosed vitamin-E-loaded nanoemulsion in rats","volume":"109","author":"Park","year":"2017","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.micpath.2024.106837_bib62","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.drudis.2017.01.016","article-title":"Is the European regulatory framework sufficient to assure the safety of citizens using health products containing nanomaterials?","volume":"22","author":"Musazzi","year":"2017","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.micpath.2024.106837_bib63","series-title":"Requirements on Measurements for the Implementation of the European Commission Definition of the Term \u2018nanomaterial\u2019. EUR 25404 EN. Luxembourg (Luxembourg):","author":"Linsinger","year":"2012"},{"key":"10.1016\/j.micpath.2024.106837_bib64","unstructured":"A. K. Demirba\u015f, S. \u00c7evik, Regulatory policies for safety of nanomaterials. OJN, 5."},{"key":"10.1016\/j.micpath.2024.106837_bib66","series-title":"Guidance for Industry Use of Nanomaterials in Food for Animals","year":"2015"},{"key":"10.1016\/j.micpath.2024.106837_bib67","series-title":"Developments in Delegations on the Safety of Manufactured Nanomaterials and Advanced Materials \u2013 Tour de Table","year":"2023"},{"key":"10.1016\/j.micpath.2024.106837_bib68","first-page":"59","article-title":"Regulation (EC) No 1223\/2009 of the European parliament and of the council of 30 november 2009 on cosmetic products","volume":"342","year":"2009","journal-title":"Off. J. EU L"},{"key":"10.1016\/j.micpath.2024.106837_bib69","series-title":"European Parliament Resolution of 24 April 2009 on Regulatory Aspects of Nanomaterials","year":"2009"},{"key":"10.1016\/j.micpath.2024.106837_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.disamonth.2020.100971","article-title":"Antimicrobial resistance, mechanisms and its clinical significance","volume":"66","author":"Abushaheen","year":"2020","journal-title":"Dis Mon."},{"key":"10.1016\/j.micpath.2024.106837_bib71","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/nrmicro3380","article-title":"Molecular mechanisms of antibiotic resistance","volume":"13","author":"Blair","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.micpath.2024.106837_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.fitote.2019.104433","article-title":"The alarming antimicrobial resistance in ESKAPEE pathogens: can essential oils come to the rescue?","volume":"140","author":"Yu","year":"2020","journal-title":"Fitoterapia"},{"key":"10.1016\/j.micpath.2024.106837_bib73","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.cbi.2019.05.050","article-title":"Synergistic interactions of phytochemicals with antimicrobial agents: potential strategy to counteract drug resistance","volume":"308","author":"Ayaz","year":"2019","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.micpath.2024.106837_bib74","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3390\/antibiotics13020163","article-title":"Use of essential oils to counteract the phenomena of antimicrobial resistance in livestock species","volume":"13","author":"Lupia","year":"2024","journal-title":"Antibiotics"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024003048?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024003048?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T11:06:03Z","timestamp":1726311963000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401024003048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":73,"alternative-id":["S0882401024003048"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106837","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nanoemulsions of essential oils against multi-resistant microorganisms: An integrative review","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106837","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106837"}}