{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T12:12:48Z","timestamp":1772539968898,"version":"3.50.1"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.micpath.2024.106974","type":"journal-article","created":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T01:40:37Z","timestamp":1726882837000},"page":"106974","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Increased antimicrobial resistance of acid-adapted pathogenic Escherichia coli, and transcriptomic analysis of polymyxin-resistant strain"],"prefix":"10.1016","volume":"196","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5606-5300","authenticated-orcid":false,"given":"Daekeun","family":"Hwang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2024.106974_bib1","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3168\/jds.S0022-0302(02)74111-8","article-title":"Effects of pH and pH fluctuations on microbial fermentation and nutrient flow from a dual-flow continuous culture system","volume":"85","author":"Calsamiglia","year":"2002","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.micpath.2024.106974_bib2","doi-asserted-by":"crossref","first-page":"11612","DOI":"10.1021\/acs.jafc.0c04274","article-title":"Chemical and sensory characteristics of soy sauce: a review","volume":"68","author":"Diez-Simon","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.micpath.2024.106974_bib3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0160-4120(03)00147-8","article-title":"Disinfection of wastewater with peracetic acid: a review","volume":"30","author":"Kitis","year":"2004","journal-title":"Environ. Int."},{"key":"10.1016\/j.micpath.2024.106974_bib4","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.jiph.2013.05.005","article-title":"Acetic acid treatment of pseudomonal wound infections \u2013 a review","volume":"6","author":"Nagoba","year":"2013","journal-title":"J. Infect. Public Health"},{"key":"10.1016\/j.micpath.2024.106974_bib5","article-title":"Hypochlorous acid as a potential wound care agent: part I. Stabilized hypochlorous acid: a component of the inorganic armamentarium of innate immunity","volume":"6","author":"Wang","year":"2007","journal-title":"J. Burns Wounds"},{"key":"10.1016\/j.micpath.2024.106974_bib6","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1007\/s10068-023-01427-6","article-title":"Survival strategies of Listeria monocytogenes to environmental hostile stress: biofilm formation and stress responses","volume":"32","author":"Byun","year":"2023","journal-title":"Food Sci. Biotechnol."},{"key":"10.1016\/j.micpath.2024.106974_bib7","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1038\/nrmicro1021","article-title":"Escherichia coli acid resistance : tales of an amateur acidophile","volume":"2","author":"Foster","year":"2004","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib8","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1128\/aem.59.6.1842-1847.1993","article-title":"Acid adaptation induces cross-protection against environmental stresses in Salmonella typhimurium","volume":"59","author":"Leyer","year":"1993","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib9","first-page":"707","article-title":"The genetic and transcriptional basis of short and long term adaptation across multiple stresses in Escherichia coli","volume":"34","author":"Zorraquino","year":"2017","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.micpath.2024.106974_bib11","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s13099-020-00390-5","article-title":"Transcriptome changes and polymyxin resistance of acid-adapted Escherichia coli O157:H7 ATCC 43889","volume":"12","author":"Hwang","year":"2020","journal-title":"Gut Pathog."},{"key":"10.1016\/j.micpath.2024.106974_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2014.00643","article-title":"Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria","author":"Olaitan","year":"2014","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib13","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s11908-017-0596-3","article-title":"Polymyxin resistance in gram-negative pathogens","volume":"19","author":"Srinivas","year":"2017","journal-title":"Curr. Infect. Dis. Rep."},{"key":"10.1016\/j.micpath.2024.106974_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.691248","article-title":"The different response to an acid shock of two Salmonella strains marks their resistance to thermal treatments","author":"Clemente-Carazo","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib15","doi-asserted-by":"crossref","first-page":"3128","DOI":"10.1128\/aem.62.9.3128-3132.1996","article-title":"Acid adaptation of Listeria monocytogenes can enhance survival in acidic foods and during milk fermentation","volume":"62","author":"Gahan","year":"1996","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib16","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0168-1605(98)00165-2","article-title":"Influence of acid tolerance responses on survival, growth, and thermal cross-protection of Escherichia coli O157:H7 in acidified media and fruit juices","volume":"45","author":"Ryu","year":"1998","journal-title":"Int. J. Food Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib17","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1080\/08905436.2021.1908345","article-title":"Comparative transcriptome analysis of virulence genes of enterohemorrhagic Escherichia coli O157:H7 to acid stress","volume":"35","author":"Zhang","year":"2021","journal-title":"Food Biotechnol"},{"key":"10.1016\/j.micpath.2024.106974_bib18","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ijid.2018.09.002","article-title":"Non-O157 Shiga toxin-producing Escherichia coli\u2014a poorly appreciated enteric pathogen: systematic review","volume":"76","author":"Valilis","year":"2018","journal-title":"Int. J. Infect. Dis."},{"key":"10.1016\/j.micpath.2024.106974_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodcont.2020.107215","article-title":"Effects of garlic addition on bacterial communities and the conversions of nitrate and nitrite in a simulated pickle fermentation system","volume":"113","author":"Huang","year":"2020","journal-title":"Food Control"},{"key":"10.1016\/j.micpath.2024.106974_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/antibiotics10050522","article-title":"Insights into emergence of antibiotic resistance in acid-adapted enterohaemorrhagic escherichia coli","volume":"10","author":"Sheikh","year":"2021","journal-title":"Antibiotics"},{"key":"10.1016\/j.micpath.2024.106974_bib22","series-title":"Recommendations for MIC Determination of Colistin (Polymyxin E) as Recommended by the Joint CLSI-EUCAST Polymyxin Breakpoints Working Group 2016","year":"2016"},{"key":"10.1016\/j.micpath.2024.106974_bib23","series-title":"OmicsBox-Bioinformatics Made Easy","year":"2019"},{"key":"10.1016\/j.micpath.2024.106974_bib24","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1093\/bioinformatics\/btz931","article-title":"ShinyGO: a graphical gene-set enrichment tool for animals and plants","volume":"36","author":"Ge","year":"2020","journal-title":"Bioinformatics"},{"key":"10.1016\/j.micpath.2024.106974_bib25","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212 \u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"methods"},{"key":"10.1016\/j.micpath.2024.106974_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2022.113449","article-title":"Insight into the antibacterial activity of lauric arginate against Escherichia coli O157:H7: membrane disruption and oxidative stress","volume":"162","author":"Zhao","year":"2022","journal-title":"Lebensm. Wiss. Technol."},{"key":"10.1016\/j.micpath.2024.106974_bib27","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/jam.13613","article-title":"Identifying the mechanism of Escherichia coli O157:H7 survival by the addition of salt in the treatment with organic acids","volume":"124","author":"Bae","year":"2018","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib28","first-page":"89","article-title":"Acid stress responses of Salmonella and E. coli: survival mechanisms, regulation, and implications for pathogenesis","volume":"39","author":"Foster","year":"2001","journal-title":"J. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib29","doi-asserted-by":"crossref","first-page":"3094","DOI":"10.1128\/aem.62.9.3094-3100.1996","article-title":"Mechanisms of acid resistance in enterohemorrhagic Escherichia coli","volume":"62","author":"Lin","year":"1996","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib30","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01579-18","article-title":"Active-site conformational fluctuations promote the enzymatic activity of NDM-1","volume":"62","author":"Zhang","year":"2018","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micpath.2024.106974_bib31","author":"Francis"},{"key":"10.1016\/j.micpath.2024.106974_bib32","doi-asserted-by":"crossref","first-page":"103","DOI":"10.13103\/JFHS.2020.35.2.103","article-title":"Correlation between food processing-associated stress tolerance and antimicrobial resistance in food pathogens","volume":"35","author":"Woode","year":"2020","journal-title":"J. Food Hyg. Saf."},{"key":"10.1016\/j.micpath.2024.106974_bib33","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1472-765X.2004.01491.x","article-title":"Comparative acid stress response of Listeria monocytogenes, Escherichia coli O157:H7 and Salmonella Typhimurium after habituation at different pH conditions","volume":"38","author":"Koutsoumanis","year":"2004","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib34","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1541-4337.2006.00002.x","article-title":"Stress response of Escherichia coli","volume":"5","author":"Chung","year":"2006","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.1016\/j.micpath.2024.106974_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0018960","article-title":"A requirement of TolC and MDR efflux pumps for acid adaptation and GadAB induction in Escherichia coli","volume":"6","author":"Deininger","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2024.106974_bib36","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.1128\/JB.01490-06","article-title":"Products of the Escherichia coli acid fitness island attenuate metabolite stress at extremely low pH and mediate a cell density-dependent acid resistance","volume":"189","author":"Mates","year":"2007","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2024.106974_bib37","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms8970","article-title":"Decoding genome-wide GadEWX-transcriptional regulatory networks reveals multifaceted cellular responses to acid stress in Escherichia coli","volume":"6","author":"Seo","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.micpath.2024.106974_bib38","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.ijantimicag.2016.06.023","article-title":"Molecular mechanisms of polymyxin resistance: knowns and unknowns","volume":"48","author":"Baron","year":"2016","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.micpath.2024.106974_bib39","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1038\/s41598-022-05435-0","article-title":"Colistin exposure enhances expression of eptB in colistin-resistant Escherichia coli co-harboring mcr-1","volume":"12","author":"Elizabeth","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2024.106974_bib40","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1128\/CMR.00064-16","article-title":"Polymyxins: antibacterial activity, susceptibility testing, and resistance mechanisms encoded by plasmids or chromosomes","volume":"30","author":"Laurent","year":"2017","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.micpath.2024.106974_bib41","doi-asserted-by":"crossref","first-page":"5181","DOI":"10.1128\/AAC.00013-14","article-title":"Serratia marcescens arn, a PhoP-regulated locus necessary for polymyxin B resistance","volume":"58","author":"Lin","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micpath.2024.106974_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2021.106426","article-title":"Polymyxin resistance in Enterobacterales: overview and epidemiology in the Americas","volume":"58","author":"Rodr\u00edguez-Santiago","year":"2021","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.micpath.2024.106974_bib43","doi-asserted-by":"crossref","first-page":"3192","DOI":"10.1093\/bioinformatics\/btaa122","article-title":"A probabilistic graphical model for system-wide analysis of gene regulatory networks","volume":"36","author":"Kotiang","year":"2020","journal-title":"Bioinformatics"},{"key":"10.1016\/j.micpath.2024.106974_bib44","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01595-20","article-title":"Gain-of-function mutations in acid stress response (evgS) protect Escherichia coli from killing by gallium nitrate, an antimicrobial candidate","volume":"65","author":"Zeng","year":"2021","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micpath.2024.106974_bib45","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/s41579-018-0048-6","article-title":"Multidrug efflux pumps: structure, function and regulation","volume":"16","author":"Du","year":"2018","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib46","article-title":"Transcriptomics reveals how minocycline-colistin synergy overcomes antibiotic resistance in multidrug-resistant Klebsiella pneumoniae","volume":"66","author":"Thea","year":"2022","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micpath.2024.106974_bib47","doi-asserted-by":"crossref","first-page":"5184","DOI":"10.1016\/j.jmb.2020.04.022","article-title":"Lipid A phosphoethanolamine transferase: regulation, structure and immune response","volume":"432","author":"Samantha","year":"2020","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.micpath.2024.106974_bib48","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1111\/mmi.14365","article-title":"Acidic pH promotes lipopolysaccharide modification and alters colonization in a bacteria\u2013animal mutualism","volume":"112","author":"Schwartzman","year":"2019","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib49","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2117009119","article-title":"Role of internal loop dynamics in antibiotic permeability of outer membrane porins","volume":"119","author":"Vasan","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.micpath.2024.106974_bib50","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.bbapap.2008.11.005","article-title":"Outer membrane permeability and antibiotic resistance","volume":"1794","author":"Delcour","year":"2009","journal-title":"Biochim. Biophys. Acta, Proteins Proteomics"},{"key":"10.1016\/j.micpath.2024.106974_bib51","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2019.00953","article-title":"Distinct roles of outer membrane porins in antibiotic resistance and membrane integrity in Escherichia coli","author":"Choi","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2024.106974_bib52","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1016\/0006-291X(92)90244-F","article-title":"Acid PH decreases OMPF and OMPC channel size in vivo","volume":"189","author":"Todt","year":"1992","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.micpath.2024.106974_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2024.127679","article-title":"A molecular overview of the polymyxin-LPS interaction in the context of its mode of action and resistance development","volume":"283","author":"Padhy","year":"2024","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.micpath.2024.106974_bib54","doi-asserted-by":"crossref","first-page":"9868","DOI":"10.1038\/s41598-018-28199-y","article-title":"Morphological, genomic and transcriptomic responses ofKlebsiella pneumoniae to the last-line antibioticcolistin","volume":"8","author":"Cain","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2024.106974_bib55","article-title":"Emerging transcriptional and genomic mechanisms mediating carbapenem and polymyxin resistance in enterobacteriaceae: a systematic review of current reports","volume":"5","author":"Masego","year":"2020","journal-title":"mSystems"},{"key":"10.1016\/j.micpath.2024.106974_bib56","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/j.1469-0691.2011.03607.x","article-title":"Membrane permeability, a pivotal function involved in antibiotic resistance and virulence in Enterobacter aerogenes clinical isolates","volume":"18","author":"Lavigne","year":"2012","journal-title":"Clin. Microbiol. Infect."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024004418?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024004418?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T22:22:54Z","timestamp":1729635774000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401024004418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":54,"alternative-id":["S0882401024004418"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106974","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased antimicrobial resistance of acid-adapted pathogenic Escherichia coli, and transcriptomic analysis of polymyxin-resistant strain","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106974","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106974"}}