{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T23:10:54Z","timestamp":1788909054749,"version":"build-2803163510"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100018895","name":"National Institute of Technology, Raipur","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.micpath.2024.106979","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T12:13:00Z","timestamp":1727179980000},"page":"106979","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Cellulase exhibited a therapeutic potential to inhibit Salmonella enterica serovar Typhi biofilm by targeting multiple regulatory proteins of biofilm"],"prefix":"10.1016","volume":"196","author":[{"given":"Aditya","family":"Upadhyay","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dharm","family":"Pal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8735-479X","authenticated-orcid":false,"given":"Awanish","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2024.106979_bib1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.procbio.2023.02.022","article-title":"Combinatorial enzyme therapy: a promising neoteric approach for bacterial biofilm disruption","volume":"129","author":"Upadhyay","year":"2023","journal-title":"Process Biochem."},{"key":"10.1016\/j.micpath.2024.106979_bib2","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23126462","article-title":"The complex mechanism of the Salmonella typhi biofilm formation that facilitates pathogenicity: a review","volume":"23","author":"Jahan","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2024.106979_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105966","article-title":"Substantial relation between the bacterial biofilm and oncogenesis progression in host","volume":"175","author":"Upadhyay","year":"2023","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2024.106979_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.adcanc.2022.100032","article-title":"Salmonella typhi induced oncogenesis in gallbladder cancer: Co-relation and progression","volume":"4","author":"Upadhayay","year":"2022","journal-title":"Adv. Cancer Biol. - Metastasis."},{"key":"10.1016\/j.micpath.2024.106979_bib5","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.bbrc.2023.05.035","article-title":"Biochemical and Biophysical Research Communications Increasing antimicrobial susceptibility of MDR Salmonella with the ef fl ux pump inhibitor 1- (1-Naphthylmethyl) -piperazine","volume":"668","author":"Price","year":"2023","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.micpath.2024.106979_bib6","article-title":"Resistance-proof antimicrobial drug discovery to combat global antimicrobial resistance threat, Drug Resist","volume":"66","author":"Upadhayay","year":"2023","journal-title":"Update"},{"key":"10.1016\/j.micpath.2024.106979_bib7","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.bbrc.2019.05.122","article-title":"Cysteine auxotrophy drives reduced susceptibility to quinolones and paraquat by inducing the expression of efflux-pump systems and detoxifying enzymes in S. Typhimurium","volume":"515","author":"Villagra","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.micpath.2024.106979_bib8","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s13756-019-0533-3","article-title":"Antibiotics versus biofilm: an emerging battleground in microbial communities","volume":"8","author":"Sharma","year":"2019","journal-title":"Antimicrob. Resist. Infect. Control"},{"key":"10.1016\/j.micpath.2024.106979_bib9","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.tim.2020.03.016","article-title":"Biofilm matrixome: extracellular components in structured microbial communities","volume":"28","author":"Karygianni","year":"2020","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.micpath.2024.106979_bib10","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.addr.2005.04.003","article-title":"Bacterial resistance to antibiotics: modified target sites","volume":"57","author":"Lambert","year":"2005","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.micpath.2024.106979_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.122418","article-title":"Interrogating Salmonella Typhi biofilm formation and dynamics to understand antimicrobial resistance","volume":"339","author":"Upadhyay","year":"2024","journal-title":"Life Sci."},{"key":"10.1016\/j.micpath.2024.106979_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2174\/1389202924666230815144126","article-title":"Deciphering target protein cascade in Salmonella typhi biofilm using genomic data mining, and protein-protein interaction","volume":"24","author":"Upadhyay","year":"2023","journal-title":"Curr. Genom."},{"key":"10.1016\/j.micpath.2024.106979_bib13","first-page":"129","article-title":"In vitro Salmonella typhi biofilm formation on gallstones and its disruption by Manuka honey","volume":"31","author":"Hannan","year":"2018","journal-title":"Pak. J. Pharm. Sci."},{"key":"10.1016\/j.micpath.2024.106979_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1009209","article-title":"Enhanced biofilm and extracellular matrix production by chronic carriage versus acute isolates of Salmonella Typhi","volume":"17","author":"Devaraj","year":"2021","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.micpath.2024.106979_bib15","doi-asserted-by":"crossref","first-page":"D605","DOI":"10.1093\/nar\/gkaa1074","article-title":"The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene\/measurement sets","volume":"49","author":"Szklarczyk","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2024.106979_bib16","doi-asserted-by":"crossref","first-page":"800","DOI":"10.12688\/f1000research.15355.1","article-title":"The Cytoscape Automation app article collection","volume":"7","author":"Demchak","year":"2018","journal-title":"F1000Research"},{"key":"10.1016\/j.micpath.2024.106979_bib17","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/978-1-4939-6798-8_14","article-title":"Investigating protein\u2013peptide interactions using the Schr\u00f6dinger computational suite","volume":"1561","author":"Bhachoo","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.micpath.2024.106979_bib18","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1080\/14728222.2024.2344699","article-title":"Molecular drilling to combat salmonella typhi biofilm using L-Asparaginase via multiple targeting process","volume":"28","author":"Upadhyay","year":"2024","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.micpath.2024.106979_bib19","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1007\/s10593-014-1496-1","article-title":"Prediction of the biological activity spectra of organic compounds using the pass online web resource","volume":"50","author":"Filimonov","year":"2014","journal-title":"Chem. Heterocycl. Compd."},{"key":"10.1016\/j.micpath.2024.106979_bib20","doi-asserted-by":"crossref","first-page":"D894","DOI":"10.1093\/nar\/gkx1157","article-title":"ABiofilm: a resource of anti-biofilm agents and their potential implications in targeting antibiotic drug resistance","volume":"46","author":"Rajput","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2024.106979_bib21","doi-asserted-by":"crossref","first-page":"W5","DOI":"10.1093\/nar\/gkab255","article-title":"ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties","volume":"49","author":"Xiong","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2024.106979_bib22","doi-asserted-by":"crossref","first-page":"W257","DOI":"10.1093\/nar\/gky318","article-title":"ProTox-II: a webserver for the prediction of toxicity of chemicals","volume":"46","author":"Banerjee","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2024.106979_bib23","first-page":"353","article-title":"Protein-protein interactions: analysis and prediction","author":"Frishman","year":"2009","journal-title":"Mod. Genome Annot. BioSapiens Netw."},{"key":"10.1016\/j.micpath.2024.106979_bib24","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.1002\/prot.23106","article-title":"The VSGB 2.0 model: a next generation energy model for high resolution protein structure modeling","volume":"79","author":"Li","year":"2011","journal-title":"Proteins: Struct., Funct., Bioinf."},{"key":"10.1016\/j.micpath.2024.106979_bib25","series-title":"In Silico Molecular Docking Studies and MM\/GBSA Analysis of Coumarin- Carbonodithioate Hybrid Derivatives Divulge the Anticancer Potential against Breast Cancer","author":"Pattar","year":"2020"},{"key":"10.1016\/j.micpath.2024.106979_bib26","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/srep32694","article-title":"A quantitative method to measure biofilm removal efficiency from complex biomaterial surfaces using SEM and image analysis","volume":"6","author":"Vyas","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2024.106979_bib27","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1039\/C9AY02214G","article-title":"Methods to probe the formation of biofilms: applications in foods and related surfaces","volume":"12","author":"Huang","year":"2020","journal-title":"Anal. Methods"},{"key":"10.1016\/j.micpath.2024.106979_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0067950","article-title":"Purification and characterization of biofilm-associated EPS exopolysaccharides from ESKAPE organisms and other pathogens","volume":"8","author":"Bales","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2024.106979_bib29","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ijfoodmicro.2013.10.005","article-title":"In situ characterization and analysis of Salmonella biofilm formation under meat processing environments using a combined microscopic and spectroscopic approach","volume":"167","author":"Wang","year":"2013","journal-title":"Int. J. Food Microbiol."},{"key":"10.1016\/j.micpath.2024.106979_bib30","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/1307397","article-title":"Raman spectroscopic characterization of endodontic biofilm matrices","volume":"2019","author":"Ramirez-Mora","year":"2019","journal-title":"J. Spectrosc."},{"key":"10.1016\/j.micpath.2024.106979_bib31","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/S0003-2697(69)80009-6","article-title":"Semimicro determination of cellulose in biological materials","volume":"32","author":"Updegraff","year":"1969","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.micpath.2024.106979_bib32","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/s41586-019-1581-9","article-title":"Low-barrier hydrogen bonds in enzyme cooperativity","volume":"573","author":"Dai","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.micpath.2024.106979_bib33","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/MOG.0000000000000406","article-title":"The evolution of antimicrobial resistance in Salmonella Typhi","volume":"34","author":"Karkey","year":"2018","journal-title":"Curr. Opin. Gastroenterol."},{"key":"10.1016\/j.micpath.2024.106979_bib34","doi-asserted-by":"crossref","first-page":"e419","DOI":"10.1016\/S2666-5247(21)00173-7","article-title":"Rising antimicrobial resistance: an evolving epidemic in a pandemic","volume":"2","author":"Manesh","year":"2021","journal-title":"Lancet Micro."},{"key":"10.1016\/j.micpath.2024.106979_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.122920","article-title":"Combinatorial therapeutic enzymes to combat multidrug resistance in bacteria","volume":"353","author":"Upadhyay","year":"2024","journal-title":"Life Sci."},{"key":"10.1016\/j.micpath.2024.106979_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2022.146995","article-title":"Emergence of sulphonamide resistance in azithromycin-resistant pediatric strains of Salmonella Typhi and Paratyphi A: a genomics insight","volume":"851","author":"Kumar","year":"2023","journal-title":"Gene"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024004467?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401024004467?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T18:23:01Z","timestamp":1729621381000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401024004467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":36,"alternative-id":["S0882401024004467"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106979","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cellulase exhibited a therapeutic potential to inhibit Salmonella enterica serovar Typhi biofilm by targeting multiple regulatory proteins of biofilm","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2024.106979","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106979"}}