{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T07:08:02Z","timestamp":1786864082238,"version":"build-2736575974"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.micpath.2025.107383","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T07:28:53Z","timestamp":1739777333000},"page":"107383","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Exposure to low concentrations of ethanol alters global gene expression patterns in Vibrio parahaemolyticus"],"prefix":"10.1016","volume":"201","author":[{"given":"Jiawen","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3935-4079","authenticated-orcid":false,"given":"Yiquan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaomiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renfei","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2025.107383_bib1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41572-018-0005-8","article-title":"Vibrio spp. infections","volume":"4","author":"Baker-Austin","year":"2018","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.micpath.2025.107383_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.117940","article-title":"Increased incidence of vibriosis in Maryland, U.S.A., 2006-2019","volume":"244","author":"Morgado","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.micpath.2025.107383_bib3","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.3201\/eid2812.220748","article-title":"Clinical and Epidemiologic Characteristics and Therapeutic Management of Patients with Vibrio Infections, Bay of Biscay, France, 2001-2019","volume":"28","author":"Hoefler","year":"2022","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.micpath.2025.107383_bib4","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12889-022-12568-4","article-title":"Surveillance for foodborne disease outbreaks in Zhejiang Province, China, 2015-2020","volume":"22","author":"Chen","year":"2022","journal-title":"BMC Public Health"},{"key":"10.1016\/j.micpath.2025.107383_bib5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0273700","article-title":"Characterization of Vibrio parahaemolyticus isolated from stool specimens of diarrhea patients in Nantong, Jiangsu, China during 2018-2020","volume":"17","author":"Sun","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2025.107383_bib6","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.micres.2019.03.003","article-title":"Molecular mechanisms of Vibrio parahaemolyticus pathogenesis","volume":"222","author":"Li","year":"2019","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.micpath.2025.107383_bib7","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s11274-018-2453-4","article-title":"The extracellular proteases produced by Vibrio parahaemolyticus","volume":"34","author":"Osei-Adjei","year":"2018","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.micpath.2025.107383_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2023.113671","article-title":"Insights into the mechanisms and key factors influencing biofilm formation by Aeromonas hydrophila in the food industry: A comprehensive review and bibliometric analysis","volume":"175","author":"Ashikur Rahman","year":"2024","journal-title":"Food Res. Int."},{"key":"10.1016\/j.micpath.2025.107383_bib9","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.tim.2008.12.004","article-title":"Vibrio biofilms: so much the same yet so different","volume":"17","author":"Yildiz","year":"2009","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib10","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1080\/10408398.2020.1746628","article-title":"Ethanol adaptation in foodborne bacterial pathogens","volume":"61","author":"He","year":"2021","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.micpath.2025.107383_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.fm.2021.103929","article-title":"Zygosaccharomyces rouxii is the predominant species responsible for the spoilage of the mix base for ice cream and ethanol is the best inhibitor tested","volume":"102","author":"Iacumin","year":"2022","journal-title":"Food Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib12","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.fm.2005.07.001","article-title":"Response of Vibrio parahaemolyticus to ethanol shock","volume":"23","author":"Chiang","year":"2006","journal-title":"Food Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib13","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.fm.2007.10.002","article-title":"Ethanol shock changes the fatty acid profile and survival behavior of Vibrio parahaemolyticus in various stress conditions","volume":"25","author":"Chiang","year":"2008","journal-title":"Food Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib14","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.ijfoodmicro.2007.11.001","article-title":"Expression of superoxide dismutase, catalase and thermostable direct hemolysin by, and growth in the presence of various nitrogen and carbon sources of heat-shocked and ethanol-shocked Vibrio parahaemolyticus","volume":"121","author":"Chiang","year":"2008","journal-title":"Int. J. Food Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib15","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.fm.2009.01.005","article-title":"Survival of Vibrio parahaemolyticus under environmental stresses as influenced by growth phase and pre-adaptation treatment","volume":"26","author":"Chiang","year":"2009","journal-title":"Food Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib16","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.4315\/0362-028X-71.11.2289","article-title":"Protein expression in Vibrio parahaemolyticus 690 subjected to sublethal heat and ethanol shock treatments","volume":"71","author":"Chiang","year":"2008","journal-title":"J. Food Protect."},{"key":"10.1016\/j.micpath.2025.107383_bib17","article-title":"Effect of sublethal dose of chloramphenicol on biofilm formation and virulence in Vibrio parahaemolyticus","volume":"14","author":"Zhang","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib18","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00203-024-04060-x","article-title":"IcmF2 of the type VI secretion system 2 plays a role in biofilm formation of Vibrio parahaemolyticus","volume":"206","author":"Huang","year":"2024","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib19","doi-asserted-by":"crossref","DOI":"10.1128\/jb.00100-23","article-title":"L-arabinose affects the growth, biofilm formation, motility, c-di-GMP metabolism, and global gene expression of Vibrio parahaemolyticus","author":"Zhang","year":"2023","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2025.107383_bib20","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/nmeth.1226","article-title":"Mapping and quantifying mammalian transcriptomes by RNA-Seq","volume":"5","author":"Mortazavi","year":"2008","journal-title":"Nat. Methods"},{"key":"10.1016\/j.micpath.2025.107383_bib21","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: kyoto encyclopedia of genes and genomes","volume":"28","author":"Kanehisa","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2025.107383_bib22","doi-asserted-by":"crossref","first-page":"D258","DOI":"10.1093\/nar\/gkh036","article-title":"The Gene Ontology (GO) database and informatics resource","volume":"32","author":"Harris","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2025.107383_bib23","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/nar\/28.1.33","article-title":"The COG database: a tool for genome-scale analysis of protein functions and evolution","volume":"28","author":"Tatusov","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2025.107383_bib24","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1471-2180-11-39","article-title":"Phenotypic and transcriptional analysis of the osmotic regulator OmpR in Yersinia pestis","volume":"11","author":"Gao","year":"2011","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib25","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.01226-21","article-title":"A Polysaccharide Biosynthesis Locus in Vibrio parahaemolyticus Important for Biofilm Formation Has Homologs Widely Distributed in Aquatic Bacteria Mainly from Gammaproteobacteria","volume":"7","author":"Liu","year":"2022","journal-title":"mSystems"},{"key":"10.1016\/j.micpath.2025.107383_bib26","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.ijbiomac.2022.10.124","article-title":"Effects of genes required for exopolysaccharides biosynthesis in Lacticaseibacillus paracasei S-NB on cell surface characteristics and probiotic properties","volume":"224","author":"Xiao","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.micpath.2025.107383_bib27","article-title":"Genetic Structure, Function, and Evolution of Capsule Biosynthesis Loci in Vibrio parahaemolyticus","volume":"11","author":"Bian","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib28","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1111\/mmi.12401","article-title":"Role of capsular polysaccharide (CPS) in biofilm formation and regulation of CPS production by quorum-sensing in Vibrio vulnificus","volume":"90","author":"Lee","year":"2013","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib29","doi-asserted-by":"crossref","first-page":"5513","DOI":"10.1128\/JB.182.19.5513-5520.2000","article-title":"Relation of capsular polysaccharide production and colonial cell organization to colony morphology in Vibrio parahaemolyticus","volume":"182","author":"Enos-Berlage","year":"2000","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2025.107383_bib30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1574-6968.2006.00438.x","article-title":"Two type IV pili of Vibrio parahaemolyticus play different roles in biofilm formation","volume":"264","author":"Shime-Hattori","year":"2006","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.micpath.2025.107383_bib31","first-page":"18","article-title":"Dual flagellar systems enable motility under different circumstances","volume":"7","author":"McCarter","year":"2004","journal-title":"J. Mol. Microbiol. Biotechnol."},{"key":"10.1016\/j.micpath.2025.107383_bib32","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01793-19","article-title":"Role of Flagellin-Homologous Proteins in Biofilm Formation by Pathogenic Vibrio Species","volume":"10","author":"Jung","year":"2019","journal-title":"mBio"},{"key":"10.1016\/j.micpath.2025.107383_bib33","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1111\/j.1365-2958.2004.04453.x","article-title":"Genetic determinants of biofilm development of opaque and translucent Vibrio parahaemolyticus","volume":"55","author":"Enos-Berlage","year":"2005","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib34","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ijfoodmicro.2012.11.004","article-title":"AphA is required for biofilm formation, motility, and virulence in pandemic Vibrio parahaemolyticus","volume":"160","author":"Wang","year":"2013","journal-title":"Int. J. Food Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib35","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.2217\/fmb-2019-0048","article-title":"Quorum sensing regulates the transcription of lateral flagellar genes in Vibrio parahaemolyticus","volume":"14","author":"Lu","year":"2019","journal-title":"Future Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib36","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13099-021-00410-y","article-title":"Transcriptional regulation of the virulence genes and the biofilm formation associated operons in Vibrio parahaemolyticus","volume":"13","author":"Zhang","year":"2021","journal-title":"Gut Pathog."},{"key":"10.1016\/j.micpath.2025.107383_bib37","first-page":"848","article-title":"ToxR Is Required for Biofilm Formation and Motility of Vibrio Parahaemolyticus","volume":"31","author":"Chen","year":"2018","journal-title":"Biomed. Environ. Sci."},{"key":"10.1016\/j.micpath.2025.107383_bib38","doi-asserted-by":"crossref","DOI":"10.1093\/lambio\/ovae059","article-title":"Identification of an LysR family transcriptional regulator that activates motility and flagellar gene expression in Vibrio parahaemolyticus","volume":"77","author":"Chang","year":"2024","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/MMBR.00043-12","article-title":"Cyclic di-GMP: the first 25 years of a universal bacterial second messenger","volume":"77","author":"R\u00f6mling","year":"2013","journal-title":"Microbiol. Mol. Biol. Rev. : MMBR (Microbiol. Mol. Biol. Rev.)"},{"key":"10.1016\/j.micpath.2025.107383_bib40","doi-asserted-by":"crossref","first-page":"18079","DOI":"10.1073\/pnas.1113790108","article-title":"Bis-(3'-5')-cyclic dimeric GMP-linked quorum sensing controls swarming in Vibrio parahaemolyticus","volume":"108","author":"Trimble","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.micpath.2025.107383_bib41","doi-asserted-by":"crossref","first-page":"4094","DOI":"10.1128\/JB.01510-06","article-title":"ScrG, a GGDEF-EAL protein, participates in regulating swarming and sticking in Vibrio parahaemolyticus","volume":"189","author":"Kim","year":"2007","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2025.107383_bib42","doi-asserted-by":"crossref","DOI":"10.1128\/aem.02239-21","article-title":"Characterization of GefA, a GGEEF Domain-Containing Protein That Modulates Vibrio parahaemolyticus Motility, Biofilm Formation, and Virulence","volume":"88","author":"Zhong","year":"2022","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib43","doi-asserted-by":"crossref","DOI":"10.1128\/JB.00409-20","article-title":"Identification of Three New GGDEF and EAL Domain-Containing Proteins Participating in the Scr Surface Colonization Regulatory Network in Vibrio parahaemolyticus","volume":"203","author":"Kimbrough","year":"2021","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2025.107383_bib44","doi-asserted-by":"crossref","DOI":"10.1128\/JB.00046-21","article-title":"A Trigger Phosphodiesterase Modulates the Global c-di-GMP Pool, Motility, and Biofilm Formation in Vibrio parahaemolyticus","volume":"203","author":"Mart\u00ednez-M\u00e9ndez","year":"2021","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2025.107383_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.113456","article-title":"Destruction of self-derived PAMP via T3SS2 effector VopY to subvert PAMP-triggered immunity mediates Vibrio parahaemolyticus pathogenicity","volume":"42","author":"Wu","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.micpath.2025.107383_bib46","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.micpath.2018.07.021","article-title":"Structure, function and regulation of the thermostable direct hemolysin (TDH) in pandemic Vibrio parahaemolyticus","volume":"123","author":"Cai","year":"2018","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2025.107383_bib47","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1348-0421.2004.tb03512.x","article-title":"Cytotoxicity and enterotoxicity of the thermostable direct hemolysin-deletion mutants of Vibrio parahaemolyticus","volume":"48","author":"Park","year":"2004","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.micpath.2025.107383_bib48","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1046\/j.1365-2958.1998.01072.x","article-title":"Manifestation of the Kanagawa phenomenon, the virulence-associated phenotype, of Vibrio parahaemolyticus depends on a particular single base change in the promoter of the thermostable direct haemolysin gene","volume":"30","author":"Okuda","year":"1998","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib49","doi-asserted-by":"crossref","first-page":"4551","DOI":"10.1128\/IAI.00461-10","article-title":"Development of two animal models to study the function of Vibrio parahaemolyticus type III secretion systems","volume":"78","author":"Pi\u00f1eyro","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2025.107383_bib50","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1128\/IAI.01051-09","article-title":"Contribution of Vibrio parahaemolyticus virulence factors to cytotoxicity, enterotoxicity, and lethality in mice","volume":"78","author":"Hiyoshi","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2025.107383_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0061086","article-title":"Vibrio parahaemolyticus type VI secretion system 1 is activated in marine conditions to target bacteria, and is differentially regulated from system 2","volume":"8","author":"Salomon","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2025.107383_bib52","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1007\/s00203-012-0816-z","article-title":"Putative type VI secretion systems of Vibrio parahaemolyticus contribute to adhesion to cultured cell monolayers","volume":"194","author":"Yu","year":"2012","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib53","doi-asserted-by":"crossref","first-page":"260","DOI":"10.4161\/viru.1.4.12318","article-title":"Regulation of type III secretion system 1 gene expression in Vibrio parahaemolyticus is dependent on interactions between ExsA, ExsC, and ExsD","volume":"1","author":"Zhou","year":"2010","journal-title":"Virulence"},{"key":"10.1016\/j.micpath.2025.107383_bib54","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0008678","article-title":"Two regulators of Vibrio parahaemolyticus play important roles in enterotoxicity by controlling the expression of genes in the Vp-PAI region","volume":"5","author":"Kodama","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2025.107383_bib55","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/S0140-6736(03)12659-1","article-title":"Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V cholerae","volume":"361","author":"Makino","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.micpath.2025.107383_bib56","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005020","article-title":"Type VI Secretion System Transports Zn2+ to Combat Multiple Stresses and Host Immunity","volume":"11","author":"Wang","year":"2015","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.micpath.2025.107383_bib57","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1099\/mic.0.000789","article-title":"The Type VI secretion system: a versatile bacterial weapon","volume":"165","author":"Coulthurst","year":"2019","journal-title":"Microbiology (Read.)"},{"key":"10.1016\/j.micpath.2025.107383_bib58","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1007\/s00253-018-9509-0","article-title":"Ethanol effects on the overexpression of heterologous catalase in Escherichia coli BL21 (DE3)","volume":"103","author":"Zheng","year":"2019","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.micpath.2025.107383_bib59","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.4315\/0362-028X.JFP-19-191","article-title":"Oxidative Disinfectants Activate Different Responses in Vibrio parahaemolyticus","volume":"82","author":"Tso","year":"2019","journal-title":"J. Food Protect."},{"key":"10.1016\/j.micpath.2025.107383_bib60","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.abb.2012.04.014","article-title":"Why do bacteria use so many enzymes to scavenge hydrogen peroxide?","volume":"525","author":"Mishra","year":"2012","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.micpath.2025.107383_bib61","doi-asserted-by":"crossref","first-page":"6771","DOI":"10.1039\/D4AY01184H","article-title":"Current trends in colorimetric biosensors using nanozymes for detecting biotoxins (bacterial food toxins, mycotoxins, and marine toxins)","volume":"16","author":"Feng","year":"2024","journal-title":"Anal. Methods : advancing methods and applications"},{"key":"10.1016\/j.micpath.2025.107383_bib62","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1016\/j.bbagen.2012.06.019","article-title":"VP2118 has major roles in Vibrio parahaemolyticus response to oxidative stress","volume":"1820","author":"Le","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.micpath.2025.107383_bib63","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms11071690","article-title":"Outer Membrane Porins Contribute to Antimicrobial Resistance in Gram-Negative Bacteria","volume":"11","author":"Zhou","year":"2023","journal-title":"Microorganisms"},{"key":"10.1016\/j.micpath.2025.107383_bib64","doi-asserted-by":"crossref","first-page":"D536","DOI":"10.1093\/nar\/gku968","article-title":"P2CS: updates of the prokaryotic two-component systems database","volume":"43","author":"Ortet","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2025.107383_bib65","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3389\/fcimb.2018.00291","article-title":"Autoregulation of ToxR and Its Regulatory Actions on Major Virulence Gene Loci in Vibrio parahaemolyticus","volume":"8","author":"Zhang","year":"2018","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib66","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1128\/IAI.06284-11","article-title":"The Vibrio parahaemolyticus ToxRS regulator is required for stress tolerance and colonization in a novel orogastric streptomycin-induced adult murine model","volume":"80","author":"Whitaker","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2025.107383_bib67","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00930-16","article-title":"Quorum Sensing Regulators Are Required for Metabolic Fitness in Vibrio parahaemolyticus","volume":"85","author":"Kalburge","year":"2017","journal-title":"Infect. Immun."},{"key":"10.1016\/j.micpath.2025.107383_bib68","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.3389\/fmicb.2017.02005","article-title":"Transcriptional Regulation of the Type VI Secretion System 1 Genes by Quorum Sensing and ToxR in Vibrio parahaemolyticus","volume":"8","author":"Zhang","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib69","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1111\/1462-2920.14524","article-title":"QsvR integrates into quorum sensing circuit to control Vibrio parahaemolyticus virulence","volume":"21","author":"Zhang","year":"2019","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib70","article-title":"OpaR Controls the Metabolism of c-di-GMP in Vibrio parahaemolyticus","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib71","article-title":"QsvR and OpaR coordinately repress biofilm formation by Vibrio parahaemolyticus","volume":"14","author":"Zhang","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib72","article-title":"Quorum sensing and QsvR tightly control the transcription of vpa0607 encoding an active RNase II-type protein in Vibrio parahaemolyticus","volume":"14","author":"Zhang","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib73","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1139\/cjm-2023-0196","article-title":"QsvR and OpaR coordinately regulate the transcription of cpsS and cpsR in Vibrio parahaemolyticus","volume":"70","author":"Li","year":"2024","journal-title":"Can. J. Microbiol."},{"key":"10.1016\/j.micpath.2025.107383_bib74","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2020.104579","article-title":"The type VI secretion system 2 of Vibrio parahaemolyticus is regulated by QsvR","volume":"149","author":"Qiu","year":"2020","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2025.107383_bib75","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1134\/S0006297913130038","article-title":"Molecular chaperone GroEL\/ES: unfolding and refolding processes","volume":"78","author":"Ryabova","year":"2013","journal-title":"Biochemistry Biokhimiia"},{"key":"10.1016\/j.micpath.2025.107383_bib76","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/j.jmb.2015.02.014","article-title":"Protein quality control under oxidative stress conditions","volume":"427","author":"Dahl","year":"2015","journal-title":"J. Mol. Biol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401025001081?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401025001081?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T03:03:33Z","timestamp":1740798213000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401025001081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":76,"alternative-id":["S0882401025001081"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107383","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exposure to low concentrations of ethanol alters global gene expression patterns in Vibrio parahaemolyticus","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107383","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107383"}}