{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T12:56:48Z","timestamp":1784293008829,"version":"3.55.0"},"reference-count":128,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T00:00:00Z","timestamp":1741219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.micpath.2025.107434","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T08:02:16Z","timestamp":1741161736000},"page":"107434","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Diagnosis and control of brucellosis through food: The contribution of omics sciences"],"prefix":"10.1016","volume":"203","author":[{"given":"Matteo","family":"Mellace","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Roncada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Tilocca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlotta","family":"Ceniti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2025.107434_bib2","series-title":"Brucellosis in Humans and Animals","author":"Corbel","year":"2006"},{"key":"10.1016\/j.micpath.2025.107434_bib3","unstructured":"The European Parliament And The Council Of The European Union. (N.D.). Regulation (Eu) 2016\/429 of the European Parliament and of the Council."},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib4","doi-asserted-by":"crossref","first-page":"151","DOI":"10.21307\/pjm-2018-029","article-title":"Brucella \u2013 virulence factors, pathogenesis and treatment","volume":"67","author":"G\u0142owacka","year":"2018","journal-title":"Pol. J. Microbiol."},{"issue":"12","key":"10.1016\/j.micpath.2025.107434_bib5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001929","article-title":"Clinical manifestations of human brucellosis: a systematic review and meta-analysis","volume":"6","author":"Dean","year":"2012","journal-title":"PLoS Neglected Trop. Dis."},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib6","doi-asserted-by":"crossref","first-page":"451","DOI":"10.2460\/javma.23.01.0033","article-title":"A one-health review on brucellosis in the United States","volume":"261","author":"Pinn-Woodcock","year":"2023","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"10.1016\/j.micpath.2025.107434_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1136674","article-title":"Research progress on complications of Brucellosis","volume":"13","author":"Jin","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"MAY","key":"10.1016\/j.micpath.2025.107434_bib8","article-title":"Retrospective and prospective perspectives on zoonotic brucellosis","volume":"5","author":"Moreno","year":"2014","journal-title":"Front. Microbiol."},{"issue":"11","key":"10.1016\/j.micpath.2025.107434_bib9","doi-asserted-by":"crossref","first-page":"9715","DOI":"10.3168\/jds.2020-18323","article-title":"MILK Symposium review: foodborne diseases from milk and milk products in developing countries\u2014review of causes and health and economic implications","volume":"103","author":"Grace","year":"2020","journal-title":"J. Dairy Sci."},{"issue":"3\u20134","key":"10.1016\/j.micpath.2025.107434_bib10","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.prevetmed.2015.03.013","article-title":"Economic losses occurring due to brucellosis in Indian livestock populations","volume":"119","author":"Singh","year":"2015","journal-title":"Prev. Vet. Med."},{"key":"10.1016\/j.micpath.2025.107434_bib11","unstructured":"Bamaiyi, P. H., & Khairani Bejo, S. (n.d.). The economic impact attributable to brucellosis among goat farms in Peninsula Malaysia and cost benefit analysis. www.roavs.com."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib12","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/01652176.2021.1894501","article-title":"Importance of brucellosis control programs of livestock on the improvement of one health","volume":"41","author":"Dadar","year":"2021","journal-title":"Vet. Q."},{"issue":"6","key":"10.1016\/j.micpath.2025.107434_bib13","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1590\/S0100-736X2013000600012","article-title":"Economic losses due to bovine brucellosis in Brazil","volume":"33","author":"Santos","year":"2013","journal-title":"Pesqui. Vet. Bras."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13690-017-0207-7","article-title":"Brucellosis in livestock and wildlife: zoonotic diseases without pandemic potential in need of innovative one health approaches","volume":"75","author":"Godfroid","year":"2017","journal-title":"Arch. Public Health"},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib15","doi-asserted-by":"crossref","DOI":"10.1080\/07853890.2023.2295398","article-title":"Brucellosis: epidemiology, pathogenesis, diagnosis and treatment\u2013a comprehensive review","volume":"55","author":"Qureshi","year":"2024","journal-title":"Ann. Med."},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib16","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2023.2249126","article-title":"The emergence of Brucella canis as a public health threat in Europe: what we know and what we need to learn","volume":"12","author":"Djokic","year":"2023","journal-title":"Emerg. Microb. Infect."},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib17","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3390\/tropicalmed3020065","article-title":"An overview of brucellosis in cattle and humans, and its serological and molecular diagnosis in control strategies","volume":"3","author":"Khan","year":"2018","journal-title":"Tropical Medicine and Infectious Disease"},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib127","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0378-1135(01)00370-4","article-title":"Comparison of an indirect ELISA with the Brucella milk ring test for detection of antibodies to Brucella abortus in bulk milk samples","volume":"82","author":"Vanzini","year":"2001","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.micpath.2025.107434_bib128","doi-asserted-by":"crossref","DOI":"10.1016\/j.prevetmed.2020.105086","article-title":"Evaluation of a milk ELISA as an alternative to a serum ELISA in the determination of the prevalence and incidence of brucellosis in dairy herds in Hubei Province, China","volume":"182","author":"Wang","year":"2020","journal-title":"Prev. Vet. Med."},{"issue":"6","key":"10.1016\/j.micpath.2025.107434_bib129","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3390\/vetsci9060303","article-title":"Evaluation of the fluorescence polarization assay for the diagnosis of brucellosis in goat milk","volume":"9","author":"Sotolongo-Rodr\u00edguez","year":"2022","journal-title":"Veterinary Sciences"},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib130","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3390\/vetsci7040175","article-title":"Development of a genus-specific Brucella real-time PCR assay targeting the 16S-23S rDNA internal transcribed spacer from different specimen types","volume":"7","author":"Nyarku","year":"2020","journal-title":"Veterinary Sciences"},{"issue":"3","key":"10.1016\/j.micpath.2025.107434_bib18","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1111\/tbed.13144","article-title":"Characterization and evolution of countries affected by bovine brucellosis (1996\u20132014)","volume":"66","author":"C\u00e1rdenas","year":"2019","journal-title":"Transboundary and Emerging Diseases"},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib19","article-title":"Comparisons of brucellosis between human and veterinary medicine","volume":"8","author":"Hull","year":"2018","journal-title":"Infect. Ecol. Epidemiol."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib20","doi-asserted-by":"crossref","first-page":"249","DOI":"10.20506\/rst.32.1.2197","article-title":"Economics of brucellosis impact and control in low-income countries","volume":"32","author":"Mcdermott","year":"2013","journal-title":"Revue Scientifique et Technique de l\u2019OIE"},{"key":"10.1016\/j.micpath.2025.107434_bib21","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.actatropica.2018.10.002","article-title":"Brucellosis seroprevalence in dairy cattle in China during 2008\u20132018: a systematic review and meta-analysis","volume":"189","author":"Ran","year":"2019","journal-title":"Acta Trop."},{"key":"10.1016\/j.micpath.2025.107434_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.onehlt.2021.100253","article-title":"Comparative proteomics of Brucella melitensis is a useful toolbox for developing prophylactic interventions in a One-Health context","volume":"13","author":"Tilocca","year":"2021","journal-title":"One Health"},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib23","doi-asserted-by":"crossref","DOI":"10.1080\/07853890.2023.2295398","article-title":"Brucellosis: epidemiology, pathogenesis, diagnosis and treatment\u2013a comprehensive review","volume":"55","author":"Qureshi","year":"2023","journal-title":"Ann. Med."},{"key":"10.1016\/j.micpath.2025.107434_bib24","author":"Sherasiya"},{"key":"10.1016\/j.micpath.2025.107434_bib25","series-title":"Brucellosis - Annual Epidemiological Report for 2022","year":"2022"},{"key":"10.1016\/j.micpath.2025.107434_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2021.104865","article-title":"Emerging diversity and ongoing expansion of the genus Brucella","volume":"92","author":"Whatmore","year":"2021","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.micpath.2025.107434_bib27","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.foodcont.2019.01.022","article-title":"Brucella-positive raw milk cheese sold on the inner European market: a public health threat due to illegal import?","volume":"100","author":"Jansen","year":"2019","journal-title":"Food Control"},{"issue":"8","key":"10.1016\/j.micpath.2025.107434_bib28","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.3390\/microorganisms10081584","article-title":"Assays for identification and differentiation of Brucella species: a review","volume":"10","author":"Kurmanov","year":"2022","journal-title":"Microorganisms"},{"key":"10.1016\/j.micpath.2025.107434_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2020.104635","article-title":"Genomic insights into Brucella","volume":"87","author":"Rajendhran","year":"2021","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.micpath.2025.107434_bib30","doi-asserted-by":"crossref","DOI":"10.31661\/gmj.v10i.1944","article-title":"A simple method for extraction of lipopolysaccharides from Brucella melitensis","volume":"10","author":"Asadikaram","year":"2021","journal-title":"Galen Medical Journal"},{"issue":"13","key":"10.1016\/j.micpath.2025.107434_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241310744","article-title":"Alr gene in Brucella suis S2: its role in lipopolysaccharide biosynthesis and bacterial virulence in RAW264.7","volume":"24","author":"Hao","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2025.107434_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.713157","article-title":"When the going gets rough: the significance of Brucella lipopolysaccharide phenotype in host\u2013pathogen interactions","volume":"12","author":"Stranahan","year":"2021","journal-title":"Front. Microbiol."},{"issue":"7","key":"10.1016\/j.micpath.2025.107434_bib33","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0000631","article-title":"Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection","volume":"2","author":"Barquero-Calvo","year":"2007","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib34","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1475-2859-5-13","article-title":"Brucella spp noncanonical LPS: structure, biosynthesis, and interaction with host immune system","volume":"5","author":"Cardoso","year":"2006","journal-title":"Microb. Cell Fact."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib35","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1080\/21505594.2017.1386831","article-title":"Immunomodulatory properties of Brucella melitensis lipopolysaccharide determinants on mouse dendritic cells in vitro and in vivo","volume":"9","author":"Zhao","year":"2018","journal-title":"Virulence"},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib36","doi-asserted-by":"crossref","DOI":"10.1128\/MMBR.00048-20","article-title":"The role of neutrophils in brucellosis","volume":"84","author":"Moreno","year":"2020","journal-title":"Microbiol. Mol. Biol. Rev."},{"issue":"6","key":"10.1016\/j.micpath.2025.107434_bib37","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1016\/j.ajpath.2015.03.003","article-title":"Pathogenesis and immunobiology of brucellosis","volume":"185","author":"de Figueiredo","year":"2015","journal-title":"Am. J. Pathol."},{"issue":"7","key":"10.1016\/j.micpath.2025.107434_bib39","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22073673","article-title":"The mechanism of facultative intracellular parasitism of brucella","volume":"22","author":"Jiao","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.micpath.2025.107434_bib40","doi-asserted-by":"crossref","DOI":"10.1128\/JB.00127-21","article-title":"An extracytoplasmic function sigma\/anti-sigma factor system regulates hypochlorous acid resistance and impacts expression of the type IV secretion system in Brucella melitensis","volume":"203","author":"Li","year":"2021","journal-title":"J. Bacteriol."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib41","doi-asserted-by":"crossref","first-page":"105","DOI":"10.20506\/rst.32.1.2193","article-title":"Pathogenesis and pathobiology of brucellosis in livestock","volume":"32","author":"Poester","year":"2013","journal-title":"Revue Scientifique et Technique de l\u2019OIE"},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib42","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/01652176.2020.1868616","article-title":"Bovine brucellosis\u2013a comprehensive review","volume":"41","author":"Khurana","year":"2021","journal-title":"Vet. Q."},{"key":"10.1016\/j.micpath.2025.107434_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2017.00506","article-title":"Brucella genital tropism: what's on the menu","volume":"8","author":"Letesson","year":"2017","journal-title":"Front. Microbiol."},{"issue":"5","key":"10.1016\/j.micpath.2025.107434_bib44","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02074-23","article-title":"Erythronate utilization activates VdtR regulating its metabolism to promote Brucella proliferation, inducing abortion in mice","volume":"11","author":"Yin","year":"2023","journal-title":"Microbiol. Spectr."},{"issue":"9","key":"10.1016\/j.micpath.2025.107434_bib45","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.3201\/eid2009.131517","article-title":"Reemergence of Brucella melitensis infection in wildlife, France","volume":"20","author":"Garin-Bastuji","year":"2014","journal-title":"Emerg. Infect. Dis."},{"issue":"3\u20134","key":"10.1016\/j.micpath.2025.107434_bib46","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.vetmic.2014.05.031","article-title":"Genetic relatedness of Brucella suis biovar 2 isolates from hares, wild boars and domestic pigs","volume":"172","author":"Kreizinger","year":"2014","journal-title":"Vet. Microbiol."},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib47","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1089\/vbz.2008.0036","article-title":"Isolation of Brucella microti from mandibular lymph nodes of red foxes, Vulpes vulpes , in lower Austria","volume":"9","author":"Scholz","year":"2009","journal-title":"Vector Borne Zoonotic Dis."},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib48","doi-asserted-by":"crossref","DOI":"10.5812\/jjm.33765","article-title":"Different clinical presentations of brucellosis","volume":"9","author":"Hasanjani Roushan","year":"2016","journal-title":"Jundishapur J. Microbiol."},{"key":"10.1016\/j.micpath.2025.107434_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.723197","article-title":"Case report: metagenomic next-generation sequencing confirmed a case of central nervous system infection with Brucella melitensis in non-endemic areas","volume":"8","author":"Cao","year":"2021","journal-title":"Front. Med."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib50","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s12879-021-07025-3","article-title":"A case of brucellosis-induced Guillain\u2013Barre syndrome","volume":"22","author":"Li","year":"2022","journal-title":"BMC Infect. Dis."},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib51","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1089\/fpd.2005.2.115","article-title":"Foodborne pathogens in milk and the dairy farm environment: food safety and public health implications","volume":"2","author":"Oliver","year":"2005","journal-title":"Foodborne Pathogens and Disease"},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib52","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s41055-021-00089-6","article-title":"A public health ethics case for mitigating zoonotic disease risk in food production","volume":"6","author":"Bernstein","year":"2021","journal-title":"Food Ethics"},{"issue":"8","key":"10.1016\/j.micpath.2025.107434_bib53","doi-asserted-by":"crossref","first-page":"4635","DOI":"10.4103\/jfmpc.jfmpc_1562_21","article-title":"The effects of health education intervention on promoting knowledge, beliefs and preventive behaviors on brucellosis among rural population in Nagpur district of Maharashtra state, India","volume":"11","author":"Ghugey","year":"2022","journal-title":"J. Fam. Med. Prim. Care"},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib54","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0008108","article-title":"Risk factors for acute human brucellosis in Ijara, north-eastern Kenya","volume":"14","author":"Kiambi","year":"2020","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.micpath.2025.107434_bib55","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ijfoodmicro.2018.12.009","article-title":"Human brucellosis caused by raw dairy products: a review on the occurrence, major risk factors and prevention","volume":"292","author":"Dadar","year":"2019","journal-title":"Int. J. Food Microbiol."},{"issue":"12","key":"10.1016\/j.micpath.2025.107434_bib56","doi-asserted-by":"crossref","first-page":"9933","DOI":"10.3168\/jds.2017-12969","article-title":"A 100-Year Review: microbiology and safety of milk handling","volume":"100","author":"Boor","year":"2017","journal-title":"J. Dairy Sci."},{"issue":"7","key":"10.1016\/j.micpath.2025.107434_bib57","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1089\/fpd.2009.0302","article-title":"Food safety hazards associated with consumption of raw milk","volume":"6","author":"Oliver","year":"2009","journal-title":"Foodborne Pathogens and Disease"},{"issue":"5","key":"10.1016\/j.micpath.2025.107434_bib58","article-title":"Direct identification and molecular characterization of zoonotic hazards in raw milk by metagenomics using brucella as a model pathogen","volume":"7","author":"Gr\u00fctzke","year":"2021","journal-title":"Microb. Genom."},{"key":"10.1016\/j.micpath.2025.107434_bib59","doi-asserted-by":"crossref","DOI":"10.7759\/cureus.8154","article-title":"Brucellosis: an elusive backyard agent","author":"Rizvi","year":"2020","journal-title":"Cureus"},{"issue":"15","key":"10.1016\/j.micpath.2025.107434_bib60","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.3390\/foods11152269","article-title":"Brucella spp. contamination in artisanal unpasteurized dairy products: an emerging foodborne threat in Tunisia","volume":"11","author":"B\u00e9jaoui","year":"2022","journal-title":"Foods"},{"issue":"10","key":"10.1016\/j.micpath.2025.107434_bib61","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001865","article-title":"Global burden of human brucellosis: a systematic review of disease frequency","volume":"6","author":"Dean","year":"2012","journal-title":"PLoS Neglected Trop. Dis."},{"issue":"5","key":"10.1016\/j.micpath.2025.107434_bib62","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0008071","article-title":"Brucellosis in the Middle East: current situation and a pathway forward","volume":"14","author":"Bagheri Nejad","year":"2020","journal-title":"PLoS Neglected Trop. Dis."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib63","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s41182-020-00272-1","article-title":"One health approach to tackle brucellosis: a systematic review","volume":"48","author":"Ghanbari","year":"2020","journal-title":"Trop. Med. Health"},{"issue":"3","key":"10.1016\/j.micpath.2025.107434_bib64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00284-023-03605-5","article-title":"The reasons behind long-term endemicity of brucellosis in low and middle-income countries: challenges and future perspectives","volume":"81","author":"Samadi","year":"2024","journal-title":"Curr. Microbiol."},{"issue":"7","key":"10.1016\/j.micpath.2025.107434_bib65","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.3390\/microorganisms10071293","article-title":"Brucellosis in humans and animals in Kyrgyzstan","volume":"10","author":"Kydyshov","year":"2022","journal-title":"Microorganisms"},{"issue":"3","key":"10.1016\/j.micpath.2025.107434_bib66","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3390\/vetsci2030135","article-title":"From \u201cone health\u201d to \u201cone communication\u201d: the contribution of communication in veterinary medicine to public health","volume":"2","author":"Cipolla","year":"2015","journal-title":"Veterinary Sciences"},{"issue":"1\u20132","key":"10.1016\/j.micpath.2025.107434_bib67","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s40592-018-0079-9","article-title":"Rethinking \u201cone health\u201d through brucellosis: ethics, boundaries and politics","volume":"37","author":"Hermesh","year":"2019","journal-title":"Monash Bioeth. Rev."},{"issue":"8","key":"10.1016\/j.micpath.2025.107434_bib68","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.3390\/microorganisms11082070","article-title":"Brucellosis and one health: inherited and future challenges","volume":"11","author":"Moriy\u00f3n","year":"2023","journal-title":"Microorganisms"},{"key":"10.1016\/j.micpath.2025.107434_bib69","unstructured":"Regulation (EC) No 852\/2004 of the European Parliament and of the Council of 29 April 2004 on the Hygiene of Foodstuffs. (n.d.)."},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib72","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1017\/S002202992100039X","article-title":"Why knowledge is the best way to reduce the risks associated with raw milk and raw milk products","volume":"88","author":"Fagnani","year":"2021","journal-title":"J. Dairy Res."},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib73","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1111\/1541-4337.12568","article-title":"Microbial quality and safety of milk and milk products in the 21st century","volume":"19","author":"Fusco","year":"2020","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"issue":"22","key":"10.1016\/j.micpath.2025.107434_bib74","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232214131","article-title":"The functional characteristics of goat cheese microbiota from a one-health perspective","volume":"23","author":"Tilocca","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2025.107434_bib75","series-title":"Techniques for the Brucellosis Laboratory","author":"Alton","year":"1988"},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib131","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1128\/JCM.02301-10","volume":"49","author":"Miguel","year":"2011","journal-title":"J. Clin. Microbiol."},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib76","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1128\/JCM.02301-10","article-title":"Development of a selective culture medium for primary isolation of the main Brucella species","volume":"49","author":"De Miguel","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micpath.2025.107434_bib77","doi-asserted-by":"crossref","DOI":"10.1093\/femsle\/fnad056","article-title":"Arapid and sensitive triplex-recombinase polymerase amplification for simultaneous differentiation of Brucella abortus, Brucella melitensis , and Brucella suis in sera and foods","volume":"370","author":"Chang","year":"2023","journal-title":"FEMS (Fed. Eur. Microbiol. Soc.) Microbiol. Lett."},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib78","first-page":"53","article-title":"Development of a differential PCR assay for detection of Brucella abortus and Brucella melitensis: an analytical approach for monitoring of Brucella spp. in foods of animal origin","volume":"3","author":"Daugaliyeva","year":"2016","journal-title":"Journal of Food Quality and Hazards Control"},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib79","doi-asserted-by":"crossref","first-page":"602","DOI":"10.3390\/biom13040602","article-title":"Recent progress in development and application of DNA, protein, peptide, glycan, antibody, and aptamer microarrays","volume":"13","author":"Aparna","year":"2023","journal-title":"Biomolecules"},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib80","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1556\/030.65.2018.028","article-title":"DNA microarray technology and bioinformatic web services","volume":"66","author":"Behzadi","year":"2018","journal-title":"Acta Microbiol. Immunol. Hung."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib81","doi-asserted-by":"crossref","first-page":"330","DOI":"10.2174\/1874285801711010330","article-title":"DNA microarray for rapid detection and identification of food and water borne bacteria: from dry to wet lab","volume":"11","author":"Ranjbar","year":"2017","journal-title":"Open Microbiol. J."},{"key":"10.1016\/j.micpath.2025.107434_bib82","doi-asserted-by":"crossref","DOI":"10.1016\/j.fm.2023.104406","article-title":"Independent evaluation of a DNA microarray system for Salmonella detection in ground beef","volume":"118","author":"Delgado","year":"2024","journal-title":"Food Microbiol."},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib83","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.3390\/biomedinformatics3040069","article-title":"Genomics for emerging pathogen identification and monitoring: prospects and obstacles","volume":"3","author":"Vashisht","year":"2023","journal-title":"BioMedInformatics"},{"issue":"11","key":"10.1016\/j.micpath.2025.107434_bib84","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1021\/acs.jproteome.0c00553","article-title":"Computational immune proteomics approach to target COVID-19","volume":"19","author":"Tilocca","year":"2020","journal-title":"J. Proteome Res."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib85","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12014-020-09278-7","article-title":"Mass spectrometry-based microbiological testing for blood stream infection","volume":"17","author":"Nomura","year":"2020","journal-title":"Clin. Proteom."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib86","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1373\/clinchem.2014.221770","article-title":"MALDI-TOF MS for the diagnosis of infectious diseases","volume":"61","author":"Patel","year":"2015","journal-title":"Clin. Chem."},{"key":"10.1016\/j.micpath.2025.107434_bib87","doi-asserted-by":"crossref","first-page":"17","DOI":"10.21775\/cimb.023.017","article-title":"MALDI-TOF MS in the microbiology laboratory: current trends","author":"Schubert","year":"2017","journal-title":"Curr. Issues Mol. Biol."},{"issue":"5","key":"10.1016\/j.micpath.2025.107434_bib88","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1128\/JCM.01794-09","article-title":"Performance of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of bacterial strains routinely isolated in a Clinical Microbiology Laboratory","volume":"48","author":"Bizzini","year":"2010","journal-title":"J. Clin. Microbiol."},{"issue":"7","key":"10.1016\/j.micpath.2025.107434_bib89","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1007\/s00216-011-4877-7","article-title":"Use of the MALDI BioTyper system with MALDI\u2013TOF mass spectrometry for rapid identification of microorganisms","volume":"400","author":"Sogawa","year":"2011","journal-title":"Anal. Bioanal. Chem."},{"issue":"12","key":"10.1016\/j.micpath.2025.107434_bib90","doi-asserted-by":"crossref","first-page":"3513","DOI":"10.1128\/JCM.01023-17","article-title":"Safety and accuracy of matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry for identification of highly pathogenic organisms","volume":"55","author":"Rudrik","year":"2017","journal-title":"J. Clin. Microbiol."},{"issue":"10","key":"10.1016\/j.micpath.2025.107434_bib91","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006874","article-title":"A MALDI-TOF MS database with broad genus coverage for species-level identification of Brucella","volume":"12","author":"Mesureur","year":"2018","journal-title":"PLoS Neglected Trop. Dis."},{"issue":"6","key":"10.1016\/j.micpath.2025.107434_bib92","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0197864","article-title":"Rapid and safe one-step extraction method for the identification of Brucella strains at genus and species level by MALDI-TOF mass spectrometry","volume":"13","author":"Sali","year":"2018","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.micpath.2025.107434_bib93","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01814-19","article-title":"Matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry for antimicrobial susceptibility testing","volume":"59","author":"Idelevich","year":"2021","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micpath.2025.107434_bib94","doi-asserted-by":"crossref","DOI":"10.1016\/j.mcp.2020.101533","article-title":"Identification of Brucella spp. isolates and discrimination from the vaccine strain Rev.1 by MALDI-TOF mass spectrometry","volume":"51","author":"Christoforidou","year":"2020","journal-title":"Mol. Cell. Probes"},{"key":"10.1016\/j.micpath.2025.107434_bib95","doi-asserted-by":"crossref","DOI":"10.1016\/j.mimet.2021.106168","article-title":"Evaluation of the matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) system in the detection of mastitis pathogens from bovine milk samples","volume":"182","author":"Jahan","year":"2021","journal-title":"J. Microbiol. Methods"},{"issue":"s1","key":"10.1016\/j.micpath.2025.107434_bib96","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.3233\/JAD-179932","article-title":"Revolution of alzheimer precision neurology. Passageway of systems biology and neurophysiology","volume":"64","author":"Hampel","year":"2018","journal-title":"J. Alzheim. Dis."},{"key":"10.1016\/j.micpath.2025.107434_bib97","article-title":"Multi-omic data integration in food science and analysis","volume":"52","author":"Herr\u00e1iz-Gil","year":"2023","journal-title":"Curr. Opin. Food Sci."},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib98","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1042\/ETLS20180174","article-title":"Uncovering complex molecular networks in host\u2013pathogen interactions using systems biology","volume":"3","author":"Peters","year":"2019","journal-title":"Emerging Topics in Life Sciences"},{"key":"10.1016\/j.micpath.2025.107434_bib99","article-title":"Application of advanced genomic tools in food safety rapid diagnostics: challenges and opportunities","volume":"47","author":"Banerjee","year":"2022","journal-title":"Curr. Opin. Food Sci."},{"key":"10.1016\/j.micpath.2025.107434_bib100","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.137943","article-title":"Multi-omics in food safety and authenticity in terms of food components","volume":"437","author":"Su","year":"2024","journal-title":"Food Chem."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib132","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1073\/pnas.221575398","volume":"99","author":"Del Vecchio","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.micpath.2025.107434_bib101","author":"Delvecchio"},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib102","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1186\/s12864-018-4762-2","article-title":"Global evolution and phylogeography of Brucella melitensis strains","volume":"19","author":"Pisarenko","year":"2018","journal-title":"BMC Genom."},{"issue":"20","key":"10.1016\/j.micpath.2025.107434_bib103","doi-asserted-by":"crossref","first-page":"7749","DOI":"10.3390\/ijms21207749","article-title":"Brucella genomics: macro and micro evolution","volume":"21","author":"Su\u00e1rez-Esquivel","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.micpath.2025.107434_bib104","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0008235","article-title":"Persistence of Brucella abortus lineages revealed by genomic characterization and phylodynamic analysis","volume":"14","author":"Su\u00e1rez-Esquivel","year":"2020","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.micpath.2025.107434_bib105","article-title":"Comparative genomic analysis provides insights into the genetic diversity and pathogenicity of the genus Brucella","volume":"15","author":"Yang","year":"2024","journal-title":"Front. Microbiol."},{"issue":"3","key":"10.1016\/j.micpath.2025.107434_bib106","doi-asserted-by":"crossref","first-page":"448","DOI":"10.4315\/JFP-21-301","article-title":"Metagenomics approaches for improving food safety: a review","volume":"85","author":"Billington","year":"2022","journal-title":"J. Food Protect."},{"key":"10.1016\/j.micpath.2025.107434_bib107","doi-asserted-by":"crossref","DOI":"10.1016\/j.gpeds.2022.100010","article-title":"Microbial and chemical hazard identification in infant food chains","volume":"2","author":"Yeak","year":"2022","journal-title":"Global Pediatrics"},{"key":"10.1016\/j.micpath.2025.107434_bib108","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2022.1002596","article-title":"Genomics and transcriptomics to protect rice (Oryza sativa. L.) from abiotic stressors: -pathways to achieving zero hunger","volume":"13","author":"Ahmad","year":"2022","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.micpath.2025.107434_bib109","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2014.00373","article-title":"Comparative analysis of Salmonella susceptibility and tolerance to the biocide chlorhexidine identifies a complex cellular defense network","volume":"5","author":"Condell","year":"2014","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2025.107434_bib110","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2019.108543","article-title":"Transcriptomics: a powerful tool to evaluate the behavior of foodborne pathogens in the food production chain","volume":"125","author":"Lamas","year":"2019","journal-title":"Food Res. Int."},{"key":"10.1016\/j.micpath.2025.107434_bib111","article-title":"Survival characteristics and transcriptome profiling reveal the adaptive response of the Brucella melitensis 16M biofilm to osmotic stress","volume":"13","author":"Guo","year":"2022","journal-title":"Front. Microbiol."},{"issue":"23","key":"10.1016\/j.micpath.2025.107434_bib112","doi-asserted-by":"crossref","first-page":"9162","DOI":"10.3390\/ijms21239162","article-title":"Bringing new methods to the seed proteomics platform: challenges and perspectives","volume":"21","author":"Smolikova","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.micpath.2025.107434_bib113","doi-asserted-by":"crossref","DOI":"10.3390\/biom10060836","article-title":"Pan-proteomic analysis and elucidation of protein abundance among the closely related brucella species, Brucella abortus and Brucella melitensis","volume":"10","author":"Murugaiyan","year":"2020","journal-title":"Biomolecules"},{"key":"10.1016\/j.micpath.2025.107434_bib114","article-title":"Using a relative quantitative proteomic method to identify differentially abundant proteins in Brucella melitensis biovar 3 and Brucella melitensis M5-90","volume":"13","author":"Zhang","year":"2022","journal-title":"Front. Immunol."},{"issue":"8","key":"10.1016\/j.micpath.2025.107434_bib115","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1021\/jasms.2c00110","article-title":"A combination of MALDI-TOF MS proteomics and species-unique biomarkers' discovery for rapid screening of brucellosis","volume":"33","author":"Hamidi","year":"2022","journal-title":"J. Am. Soc. Mass Spectrom."},{"issue":"5","key":"10.1016\/j.micpath.2025.107434_bib116","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17050659","article-title":"Comprehensive identification of immunodominant proteins of Brucella abortus and Brucella melitensis using antibodies in the sera from naturally infected hosts","volume":"17","author":"Wareth","year":"2016","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.micpath.2025.107434_bib117","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1007\/s11427-011-4218-2","article-title":"Identification of immunoreactive proteins of Brucella melitensis by immunoproteomics","volume":"54","author":"Zhao","year":"2011","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.micpath.2025.107434_bib118","article-title":"Integrated proteomic and transcriptomic analyses reveal the roles of Brucella homolog of BAX inhibitor 1 in cell division and membrane homeostasis of Brucella suis S2","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Microbiol."},{"issue":"3","key":"10.1016\/j.micpath.2025.107434_bib119","doi-asserted-by":"crossref","DOI":"10.15252\/msb.20167062","article-title":"Proteomics and integrative omic approaches for understanding host\u2013pathogen interactions and infectious diseases","volume":"13","author":"Jean Beltran","year":"2017","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.micpath.2025.107434_bib120","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1253349","article-title":"Immuno-profiling of Brucella proteins for developing improved vaccines and DIVA capable serodiagnostic assays for brucellosis","volume":"14","author":"Nandini","year":"2023","journal-title":"Front. Microbiol."},{"issue":"1","key":"10.1016\/j.micpath.2025.107434_bib121","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3390\/microbiolres12010006","article-title":"Food safety concerns in \u201cCOVID-19 era\u201d","volume":"12","author":"Ceniti","year":"2021","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.micpath.2025.107434_bib122","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/1214391","article-title":"Optimal control strategies for the infectiology of brucellosis","author":"Nyerere","year":"2020","journal-title":"Int. J. Math. Math. Sci."},{"issue":"6","key":"10.1016\/j.micpath.2025.107434_bib123","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1007\/s10745-022-00361-1","article-title":"Understanding factors that shape exposure to zoonotic and food-borne diseases across wild meat trade chains","volume":"50","author":"van Vliet","year":"2022","journal-title":"Hum. Ecol."},{"issue":"2","key":"10.1016\/j.micpath.2025.107434_bib124","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3390\/jpm11020135","article-title":"Precision medicine and public health: new challenges for effective and sustainable health","volume":"11","author":"Traversi","year":"2021","journal-title":"J. Personalized Med."},{"issue":"6","key":"10.1016\/j.micpath.2025.107434_bib125","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1080\/08830185.2019.1657426","article-title":"Immunoinformatics: in silico approaches and computational design of a multi-epitope, immunogenic protein","volume":"38","author":"Bahrami","year":"2019","journal-title":"Int. Rev. Immunol."},{"issue":"6","key":"10.1016\/j.micpath.2025.107434_bib126","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.it.2009.03.009","article-title":"Enabling a systems biology approach to immunology: focus on innate immunity","volume":"30","author":"Gardy","year":"2009","journal-title":"Trends Immunol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401025001597?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401025001597?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:27:19Z","timestamp":1744259239000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401025001597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":128,"alternative-id":["S0882401025001597"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107434","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnosis and control of brucellosis through food: The contribution of omics sciences","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107434","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"107434"}}