{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:16:17Z","timestamp":1786994177784,"version":"build-2736575974"},"reference-count":86,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002378","name":"Faculty of Veterinary Medicine, Cairo University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002378","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.micpath.2025.107511","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T14:39:51Z","timestamp":1742999991000},"page":"107511","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["In vitro and in vivo attenuation of Salmonella resistance using a novel synthesized chloramphenicol magnesium Nano-complex"],"prefix":"10.1016","volume":"203","author":[{"given":"Farag M.","family":"Mosallam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maha A.","family":"Shafik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shimaa A.","family":"Abd Elmawgoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A.","family":"EL-Saied","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana M.","family":"Elshimy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2025.107511_bib1","series-title":"An Antisalmonellal Agent from the Leaves of Glossocalyx Brevipes Benth (Monimiaceae)","author":"Gatsing","year":"2006"},{"key":"10.1016\/j.micpath.2025.107511_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2193-1801-3-302","article-title":"Antityphoid and radical scavenging properties of the methanol extracts and compounds from the aerial part of Paullinia pinnata","volume":"3","author":"Lunga","year":"2014","journal-title":"SpringerPlus"},{"key":"10.1016\/j.micpath.2025.107511_bib3","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1007\/s42770-023-01138-4","article-title":"Assignment of the antibacterial potential of Ag2O\/ZnO nanocomposite against MDR bacteria Proteus mirabilis and Salmonella typhi isolated from bone marrow transplant patients","volume":"54","author":"El-Mohsnawy","year":"2023","journal-title":"Braz. J. Microbiol."},{"key":"10.1016\/j.micpath.2025.107511_bib4","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3390\/biomimetics6020034","article-title":"Application of response surface methodology for optimizing the therapeutic activity of ZnO nanoparticles biosynthesized from Aspergillus Niger","volume":"6","author":"Es-Haghi","year":"2021","journal-title":"Biomimetics"},{"key":"10.1016\/j.micpath.2025.107511_bib5","series-title":"Anti-microbial Activity of Biologically Stabilized Silver Nano Particles","author":"Paknikar","year":"2007"},{"key":"10.1016\/j.micpath.2025.107511_bib6","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1128\/AEM.02218-06","article-title":"Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the gram-negative bacterium Escherichia coli","volume":"73","author":"Pal","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2025.107511_bib7","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1590\/0104-6632.20140313s00002813","article-title":"MgO nanoparticles as antibacterial agent: preparation and activity","volume":"31","author":"Tang","year":"2014","journal-title":"Braz. J. Chem. Eng."},{"key":"10.1016\/j.micpath.2025.107511_bib8","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-34567-5","article-title":"Antimicrobial activities and mechanisms of magnesium oxide nanoparticles (nMgO) against pathogenic bacteria, yeasts, and biofilms","volume":"8","author":"Nguyen","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2025.107511_bib9","first-page":"16","article-title":"Reduced minimum inhibitory concentration of chloramphenicol for Salmonella enterica serovar typhi","volume":"58","author":"Mandal","year":"2004","journal-title":"Indian J. Med. Sci."},{"key":"10.1016\/j.micpath.2025.107511_bib10","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/S0377-1237(05)80011-5","article-title":"Outbreak of multi-drug resistant Salmonella Typhi enteric fever in Mumbai Garrison","volume":"61","author":"Misra","year":"2005","journal-title":"Med. J. Armed Forces India"},{"key":"10.1016\/j.micpath.2025.107511_bib11","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/15533170902762587","article-title":"Synthesis and antibacterial studies of chloramphenicol loaded nano-silver against Salmonella typhi","volume":"39","author":"Patil","year":"2009","journal-title":"Synth. React. Inorganic, Metal-Organic, And Nano-Metal Chem."},{"key":"10.1016\/j.micpath.2025.107511_bib12","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.3390\/molecules28041603","article-title":"Hybrid nanosystems of antibiotics with metal nanoparticles\u2014novel antibacterial agents","volume":"28","author":"Shabatina","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.micpath.2025.107511_bib13","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0890-8508(92)90002-F","article-title":"Amplification of an invA gene sequence of Salmonella typhimurium by polymerase chain reaction as a specific method of detection of Salmonella","volume":"6","author":"Rahn","year":"1992","journal-title":"Mol. Cell. Probes"},{"key":"10.1016\/j.micpath.2025.107511_bib14","series-title":"Isolation of Salmonella Typhimurium from Poultry Eggs and Meat of Tarai Region of Uttaranchal","author":"Nagappa","year":"2007"},{"key":"10.1016\/j.micpath.2025.107511_bib15","series-title":"Performance Standards for Antimicrobial Susceptibility Testing","first-page":"106","author":"Clinical","year":"2017"},{"key":"10.1016\/j.micpath.2025.107511_bib16","article-title":"European committee on antimicrobial susceptibility testing breakpoint tables for interpretation of MICs and zone diameters","volume":"12","author":"EcoAS","year":"2015","journal-title":"EUCAST Clinical Breakpoint Tables"},{"key":"10.1016\/j.micpath.2025.107511_bib17","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1016\/j.apsb.2022.11.020","article-title":"Ultrasmall iron-quercetin metal natural product nanocomplex with antioxidant and macrophage regulation in rheumatoid arthritis","volume":"13","author":"Han","year":"2023","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.micpath.2025.107511_bib18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.5101\/nbe.v12i2.p139-147","article-title":"Nanoscale synthesis of metal (II) theophylline complexes and assessment of their biological activity","volume":"12","author":"Ismail","year":"2020","journal-title":"Nano Biomed Eng."},{"key":"10.1016\/j.micpath.2025.107511_bib19","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1016\/j.ijbiomac.2019.10.097","article-title":"Fabrication and characterization of cobalt hyaluronic acid nanostructure via gamma irradiation for improving biomedical applications","volume":"147","author":"El-Batal","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.micpath.2025.107511_bib20","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.ijpharm.2008.07.013","article-title":"Stability and bioactivity of nanocomplex of TNF-related apoptosis-inducing ligand","volume":"363","author":"Na","year":"2008","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.micpath.2025.107511_bib21","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s13201-023-01987-2","article-title":"Biosynthesis of magnesium oxide nanoparticles using Hagenia abyssinica female flower aqueous extract for characterization and antibacterial activity","volume":"13","author":"Hirphaye","year":"2023","journal-title":"Appl. Water Sci."},{"key":"10.1016\/j.micpath.2025.107511_bib22","doi-asserted-by":"crossref","first-page":"977","DOI":"10.5897\/AJMR2017.8545","article-title":"Determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) using a novel dilution tube method","volume":"11","author":"Owuama","year":"2017","journal-title":"Afr. J. Microbiol. Res."},{"key":"10.1016\/j.micpath.2025.107511_bib23","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1097\/ICO.0b013e31823f8ae0","article-title":"Organism, minimum inhibitory concentration, and outcome in a fungal corneal ulcer clinical trial","volume":"31","author":"Lalitha","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.micpath.2025.107511_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0227023","article-title":"Antimicrobial activity of Asteraceae species against bacterial pathogens isolated from postmenopausal women","volume":"15","author":"Chiavari-Frederico","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2025.107511_bib25","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/26415275.2020.1796674","article-title":"The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of silver nanoparticles against Staphylococcus aureus","volume":"7","author":"Parvekar","year":"2020","journal-title":"Biomater. Investigat. Dent."},{"key":"10.1016\/j.micpath.2025.107511_bib26","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1007\/s00284-009-9424-9","article-title":"Tetracycline and chloramphenicol efficiency against selected biofilm forming bacteria","volume":"59","author":"Liaqat","year":"2009","journal-title":"Curr. Microbiol."},{"key":"10.1016\/j.micpath.2025.107511_bib27","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3390\/antibiotics11010079","article-title":"In vitro and in silico approaches for the evaluation of antimicrobial activity, time-kill kinetics, and anti-biofilm potential of thymoquinone (2-Methyl-5-propan-2-ylcyclohexa-2, 5-diene-1, 4-dione) against selected human pathogens","volume":"11","author":"Qureshi","year":"2022","journal-title":"Antibiotics"},{"key":"10.1016\/j.micpath.2025.107511_bib28","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1093\/jac\/dkv488","article-title":"Dynamic interaction of colistin and meropenem on a WT and a resistant strain of Pseudomonas aeruginosa as quantified in a PK\/PD model","volume":"71","author":"Mohamed","year":"2016","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.micpath.2025.107511_bib29","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.3109\/13880209.2014.893001","article-title":"Antimicrobial activity of zinc oxide (ZnO) nanoparticle against Klebsiella pneumoniae","volume":"52","author":"Reddy","year":"2014","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.micpath.2025.107511_bib30","first-page":"505","article-title":"Immunomodulatory activity of methanolic extract of Murraya koenigii (L) Spreng. leaves","volume":"46","author":"Shah","year":"2008","journal-title":"Indian J. Exp. Biol."},{"key":"10.1016\/j.micpath.2025.107511_bib31","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1440-1681.2006.04329.x","article-title":"Activities of aqueous extracts of Mallotus oppositifolium on Shigella dysenteriae A1\u2010induced diarrhoea in rats","volume":"33","author":"Kamgang","year":"2006","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.micpath.2025.107511_bib32","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.micpath.2025.107511_bib33","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/jat.3760","article-title":"Acute and subacute oral toxicity of copper oxide nanoparticles in female albino Wistar rats","volume":"39","author":"Bugata","year":"2019","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.micpath.2025.107511_bib34","doi-asserted-by":"crossref","first-page":"21391","DOI":"10.1021\/acsomega.3c02239","article-title":"Advances in nanotechnology for biofilm inhibition","volume":"8","author":"Kumar","year":"2023","journal-title":"ACS Omega"},{"key":"10.1016\/j.micpath.2025.107511_bib35","doi-asserted-by":"crossref","first-page":"6462","DOI":"10.3390\/ijms23126462","article-title":"The complex mechanism of the Salmonella typhi biofilm formation that facilitates pathogenicity: a review","volume":"23","author":"Jahan","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2025.107511_bib36","doi-asserted-by":"crossref","first-page":"15411","DOI":"10.1021\/acsnano.3c00981","article-title":"Antibiotic\u2013polymer self-assembled nanocomplex to reverse phenotypic resistance of bacteria toward last-resort antibiotic colistin","volume":"17","author":"Zhao","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.micpath.2025.107511_bib37","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s43440-023-00482-4","article-title":"Nanoparticles coated by chloramphenicol in hydrogels as a useful tool to increase the antibiotic release and antibacterial activity in dermal drug delivery","volume":"75","author":"Bursy","year":"2023","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.micpath.2025.107511_bib38","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.jscs.2015.10.002","article-title":"Effect of Gamma-irradiation on biosynthesized gold nanoparticles using Chenopodium murale leaf extract","volume":"21","author":"Abdelghany","year":"2017","journal-title":"J. Saudi Chem. Soc."},{"key":"10.1016\/j.micpath.2025.107511_bib39","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6679637","article-title":"Gamma irradiation\u2010assisted synthesis of silver nanoparticle\u2010embedded graphene oxide\u2010TiO2 nanotube nanocomposite for organic dye photodegradation","volume":"2021","author":"Vu","year":"2021","journal-title":"J. Nanomater."},{"key":"10.1016\/j.micpath.2025.107511_bib40","series-title":"Effect of Gamma Radiation on the Microbial Synthesis of Metal Nanoparticles","author":"Mosalam","year":"2013"},{"key":"10.1016\/j.micpath.2025.107511_bib41","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.3390\/nano13101666","article-title":"Gamma radiation synthesis of Ag\/P25 nanocomposites for efficient photocatalytic degradation of organic contaminant","volume":"13","author":"Zeng","year":"2023","journal-title":"Nanomaterials"},{"key":"10.1016\/j.micpath.2025.107511_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.radphyschem.2018.08.011","article-title":"Gamma-irradiation applied in the synthesis of metallic and organic nanoparticles: a short review","volume":"169","author":"Flores-Rojas","year":"2020","journal-title":"Radiat. Phys. Chem."},{"key":"10.1016\/j.micpath.2025.107511_bib43","first-page":"1","article-title":"The influence of gamma irradiation on linear and nonlinear optical properties of magnesium oxide nanoparticles via Z-scan technique","author":"Nadafan","year":"2022","journal-title":"J. Australian Ceram. Soc."},{"key":"10.1016\/j.micpath.2025.107511_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.mechmat.2020.103318","article-title":"Computational and experimental study of mechanical properties of Nylon 6 nanocomposites reinforced with nanomilled cellulose","volume":"143","author":"Krishna","year":"2020","journal-title":"Mech. Mater."},{"key":"10.1016\/j.micpath.2025.107511_bib45","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1049\/nde2.12034","article-title":"Identification of nanocomposites agglomerates in scanning electron microscopy images based on semantic segmentation","volume":"5","author":"Bai","year":"2022","journal-title":"IET Nanodielectrics"},{"key":"10.1016\/j.micpath.2025.107511_bib46","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3390\/colloids7010015","article-title":"Dynamic light scattering: a powerful tool for in situ nanoparticle sizing","volume":"7","author":"Jia","year":"2023","journal-title":"Colloids and Interfaces"},{"key":"10.1016\/j.micpath.2025.107511_bib47","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.ijheatmasstransfer.2014.10.019","article-title":"Brownian movement and thermophoresis of nanoparticles in liquids","volume":"81","author":"Michaelides","year":"2015","journal-title":"Int. J. Heat Mass Tran."},{"key":"10.1016\/j.micpath.2025.107511_bib48","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3390\/mi15010024","article-title":"Dynamic light scattering and its application to control nanoparticle aggregation in colloidal systems: a review","volume":"15","author":"Rodriguez-Loya","year":"2023","journal-title":"Micromachines"},{"key":"10.1016\/j.micpath.2025.107511_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2021.130235","article-title":"Novel nanoparticle-size metal complexes derived from acyclovir. Spectroscopic characterization, thermal analysis, antitumor screening, and DNA cleavage, as well as 3D modeling, docking, and electrical conductivity studies","volume":"1235","author":"El-ghamry","year":"2021","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.micpath.2025.107511_bib50","doi-asserted-by":"crossref","first-page":"5273","DOI":"10.1039\/D1CC07265J","article-title":"Controlled polymerization of metal complex monomers\u2013fabricating random copolymers comprising different metal species and nano-colloids","volume":"58","author":"Osawa","year":"2022","journal-title":"Chem. Commun."},{"key":"10.1016\/j.micpath.2025.107511_bib51","article-title":"Antibacterial mechanism of lignin and lignin-based antimicrobial materials in different fields","author":"Li","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.micpath.2025.107511_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.mycmed.2024.101489","article-title":"Novel griseofulvin zinc nanohybrid emulsion for intensifying the antimicrobial control of dermatophytes and some opportunistic pathogens","author":"Mosallam","year":"2024","journal-title":"J. Med. Mycol."},{"key":"10.1016\/j.micpath.2025.107511_bib53","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/978-1-60327-198-1_6","article-title":"Zeta potential measurement","author":"Clogston","year":"2011","journal-title":"Characterization of nanoparticles intended for drug delivery"},{"key":"10.1016\/j.micpath.2025.107511_bib54","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.foodhyd.2017.07.029","article-title":"Formation and stability of anthocyanins-loaded nanocomplexes prepared with chitosan hydrochloride and carboxymethyl chitosan","volume":"74","author":"Ge","year":"2018","journal-title":"Food Hydrocoll."},{"key":"10.1016\/j.micpath.2025.107511_bib55","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.2147\/IDR.S204618","article-title":"Sensitivity pattern of Salmonella typhi and Paratyphi A isolates to chloramphenicol and other anti-typhoid drugs: an in vitro study","author":"Patil","year":"2019","journal-title":"Infect. Drug Resist."},{"key":"10.1016\/j.micpath.2025.107511_bib56","series-title":"Prevalence and Antimicrobial Susceptibility Pattern of Salmonella enterica Serovar Typhi and Salmonella enterica Serovar Paratyphi Among Febrile Patients at Karamara Hospital, Jigjiga, Eastern Ethiopia","volume":"vol. 7","author":"Admassu","year":"2019"},{"key":"10.1016\/j.micpath.2025.107511_bib57","doi-asserted-by":"crossref","first-page":"6993","DOI":"10.2147\/IJN.S270204","article-title":"The role of silver nanoparticles in a treatment approach for multidrug-resistant Salmonella species isolates","author":"Farouk","year":"2020","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.micpath.2025.107511_bib58","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.3390\/antibiotics12061005","article-title":"Combating bacterial biofilms: current and emerging antibiofilm strategies for treating persistent infections","volume":"12","author":"Abdelhamid","year":"2023","journal-title":"Antibiotics"},{"key":"10.1016\/j.micpath.2025.107511_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.129594","article-title":"Charge-switchable MOF nanocomplex for enhanced biofilm penetration and eradication","volume":"439","author":"Ding","year":"2022","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.micpath.2025.107511_bib60","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.1039\/C9BM00057G","article-title":"Synthesis of magnetite hybrid nanocomplexes to eliminate bacteria and enhance biofilm disruption","volume":"7","author":"Zhang","year":"2019","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.micpath.2025.107511_bib61","article-title":"Polyelectrolyte nanocomplex formation combined with electrostatic self-assembly enables the co-delivery of synergistic antimicrobials to treat bacterial biofilms","volume":"2021.11. 22","author":"Finbloom","year":"2021","journal-title":"bioRxiv"},{"key":"10.1016\/j.micpath.2025.107511_bib62","doi-asserted-by":"crossref","first-page":"839","DOI":"10.3390\/antibiotics10070839","article-title":"Silver nanoparticles enhance antimicrobial efficacy of antibiotics and restore that efficacy against the melioidosis pathogen","volume":"10","author":"Malawong","year":"2021","journal-title":"Antibiotics"},{"key":"10.1016\/j.micpath.2025.107511_bib63","first-page":"84","article-title":"Biogenic synthesis of silver nanoparticles and their synergistic effect with antibiotics: a study against Salmonella sp","volume":"7","author":"Krishna","year":"2015","journal-title":"Int. J. Pharm. Pharmaceut. Sci."},{"key":"10.1016\/j.micpath.2025.107511_bib64","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1080\/10590501.2015.1055165","article-title":"Synergistic antibacterial effect of silver nanoparticles combined with ineffective antibiotics on drug resistant Salmonella typhimurium DT104","volume":"33","author":"McShan","year":"2015","journal-title":"J. Environ. Sci. Health, Part C."},{"key":"10.1016\/j.micpath.2025.107511_bib65","article-title":"Synergistic effects of silver nanoparticles in combination with ineffective antibiotics against multidrug resistant Salmonella typhi","volume":"40","author":"Maqsood","year":"2024","journal-title":"Pakistan J. Med. Sci."},{"key":"10.1016\/j.micpath.2025.107511_bib66","doi-asserted-by":"crossref","first-page":"962","DOI":"10.5187\/jast.2023.e91","article-title":"Evaluation of zinc oxide and copper oxide nanoparticles as potential alternatives to antibiotics for managing fowl typhoid in broilers","volume":"66","author":"Raza","year":"2024","journal-title":"J. Anim. Sci. Technol."},{"key":"10.1016\/j.micpath.2025.107511_bib67","first-page":"948","article-title":"Effect of dietary selenium nanoparticles supplementation on hematological, serum biochemical, oxidant-antioxidant biomarkers, and proinflammatory cytokines in broilers challenged with Salmonella typhimurium","volume":"13","author":"Allam","year":"2023","journal-title":"J. Adv. Vet. Res."},{"key":"10.1016\/j.micpath.2025.107511_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2021.129928","article-title":"A review of the nanomaterials use for the diagnosis and therapy of salmonella typhi","volume":"1230","author":"Arshad","year":"2021","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.micpath.2025.107511_bib69","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1007\/s00775-014-1199-1","article-title":"A novel tool for capture and detection of typhoid fever using Ag-labeled nanocomposites","volume":"19","author":"Chattopadhyay","year":"2014","journal-title":"JBIC, J. Biol. Inorg. Chem."},{"key":"10.1016\/j.micpath.2025.107511_bib70","article-title":"Nanotechnology for the treatment of paediatric diseases: a review","volume":"75","author":"Marques","year":"2022","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"10.1016\/j.micpath.2025.107511_bib71","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-03264-1","article-title":"Alginate-amphotericin B nanocomplexes covered by nanocrystals from bacterial cellulose: physico-chemical characterization and in vitro toxicity","volume":"11","author":"Soeiro","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2025.107511_bib72","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3390\/gels7030096","article-title":"Preparation, optimization and evaluation of chitosan-based avanafil nanocomplex utilizing antioxidants for enhanced neuroprotective effect on PC12 cells","volume":"7","author":"Kurakula","year":"2021","journal-title":"Gels"},{"key":"10.1016\/j.micpath.2025.107511_bib73","doi-asserted-by":"crossref","DOI":"10.3390\/app112210695","article-title":"Application of polymeric nanocarriers for enhancing the bioavailability of antibiotics at the target site and overcoming antimicrobial resistance","volume":"11","author":"Le","year":"2021","journal-title":"Appl. Sci."},{"key":"10.1016\/j.micpath.2025.107511_bib74","first-page":"2971","article-title":"Chloramphenicol encapsulated in poly-\u03b5-caprolactone\u2013pluronic composite: nanoparticles for treatment of MRSA-infected burn wounds","author":"Kalita","year":"2015","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.micpath.2025.107511_bib75","doi-asserted-by":"crossref","first-page":"94236","DOI":"10.1039\/C5RA18450A","article-title":"Fluorescent magnesium nanocomplex in a protein scaffold for cell nuclei imaging applications","volume":"5","author":"Pandya","year":"2015","journal-title":"RSC Adv."},{"key":"10.1016\/j.micpath.2025.107511_bib76","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1177\/1091581816648624","article-title":"In vitro toxicological assessment of magnesium oxide nanoparticle exposure in several mammalian cell types","volume":"35","author":"Mahmoud","year":"2016","journal-title":"Int. J. Toxicol."},{"key":"10.1016\/j.micpath.2025.107511_bib77","first-page":"913","article-title":"Chloramphenicol arrests transition of cell cycle and induces apoptotic cell death in myelogenous leukemia cells","volume":"15","author":"Young","year":"2005","journal-title":"J. Microbiol. Biotechnol."},{"key":"10.1016\/j.micpath.2025.107511_bib78","first-page":"1","article-title":"Toxicology of nanoparticles in drug delivery","author":"Sharma","year":"2021","journal-title":"Curr. Pathobiol. Rep."},{"key":"10.1016\/j.micpath.2025.107511_bib79","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/s41579-020-0420-1","article-title":"Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections","volume":"19","author":"Makabenta","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.micpath.2025.107511_bib80","doi-asserted-by":"crossref","first-page":"4164","DOI":"10.1016\/j.sjbs.2021.05.032","article-title":"Nanoparticles combined with cefixime as an effective synergistic strategy against Salmonella enterica typhi","volume":"28","author":"Kapadia","year":"2021","journal-title":"Saudi J. Biol. Sci."},{"key":"10.1016\/j.micpath.2025.107511_bib81","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s13204-014-0293-6","article-title":"The green synthesis, characterization, and evaluation of the biological activities of silver nanoparticles synthesized from Leptadenia reticulata leaf extract","volume":"5","author":"Kumara Swamy","year":"2015","journal-title":"Appl. Nanosci."},{"key":"10.1016\/j.micpath.2025.107511_bib82","doi-asserted-by":"crossref","first-page":"609","DOI":"10.18388\/abp.2016_1495","article-title":"Effects and time-kill assessment of amoxicillin used in combination with chloramphenicol against bacteria of clinical importance","volume":"64","author":"Olajuyigbe","year":"2017","journal-title":"Acta Biochim. Pol."},{"key":"10.1016\/j.micpath.2025.107511_bib83","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1023\/A:1008916209784","article-title":"Antibacterial characteristics of magnesium oxide powder","volume":"16","author":"Sawai","year":"2000","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.micpath.2025.107511_bib84","doi-asserted-by":"crossref","first-page":"6877","DOI":"10.1007\/s11051-011-0595-5","article-title":"Antibacterial activities of magnesium oxide (MgO) nanoparticles against foodborne pathogens","volume":"13","author":"Jin","year":"2011","journal-title":"J. Nanoparticle Res."},{"key":"10.1016\/j.micpath.2025.107511_bib85","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3390\/jfb14020112","article-title":"Synthesis and spectral characterisation of fabricated cerium-doped magnesium oxide nanoparticles: evaluation of the antimicrobial potential and its membranolytic activity through large unilamellar vesicles","volume":"14","author":"Khatua","year":"2023","journal-title":"J. Funct. Biomater."},{"key":"10.1016\/j.micpath.2025.107511_bib86","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.colsurfb.2015.01.012","article-title":"Comparative efficacy of chloramphenicol loaded chondroitin sulfate and dextran sulfate nanoparticles to treat intracellular Salmonella infections","volume":"127","author":"Kiruthika","year":"2015","journal-title":"Colloids Surf. B Biointerfaces"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401025002360?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401025002360?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T03:01:15Z","timestamp":1762311675000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401025002360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":86,"alternative-id":["S0882401025002360"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107511","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In vitro and in vivo attenuation of Salmonella resistance using a novel synthesized chloramphenicol magnesium Nano-complex","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107511","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107511"}}