{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T15:41:31Z","timestamp":1784734891886,"version":"3.55.0"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.micpath.2025.107634","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T02:06:49Z","timestamp":1745806009000},"page":"107634","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Molecular and computational insights into algD biofilm genes in multi drug resistant and extensively drug resistant Pseudomonas aeruginosa"],"prefix":"10.1016","volume":"205","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8025-9404","authenticated-orcid":false,"given":"Muhammad Bilal","family":"Habib","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naseer Ali","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afreenish","family":"Amir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4767-5430","authenticated-orcid":false,"given":"Muhammad Haseeb","family":"Tariq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2025.107634_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.926758","article-title":"Virulence factors of Pseudomonas aeruginosa and antivirulence strategies to combat its drug resistance","volume":"12","author":"Liao","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib2","doi-asserted-by":"crossref","first-page":"3128","DOI":"10.3390\/ijms22063128","article-title":"Pseudomonas aeruginosa: an audacious pathogen with an adaptable arsenal of virulence factors","volume":"22","author":"Jurado-Mart\u00edn","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2025.107634_bib3","doi-asserted-by":"crossref","first-page":"32","DOI":"10.14715\/cmb\/2023.69.5.6","article-title":"Molecular detection of different virulence factors genes harbor pslA, pelA, exoS, toxA and algD among biofilm-forming clinical isolates of Pseudomonas aeruginosa","volume":"69","author":"Farhan","year":"2023","journal-title":"Cell. Mol. Biol."},{"key":"10.1016\/j.micpath.2025.107634_bib4","doi-asserted-by":"crossref","first-page":"180","DOI":"10.4067\/S0716-10182019000200180","article-title":"Pseudomonas aeruginosa: patogenicidad y resistencia antimicrobiana en la infecci\u00f3n urinaria","volume":"36","author":"Paz-Zarza","year":"2019","journal-title":"Rev. Chil. infectol."},{"key":"10.1016\/j.micpath.2025.107634_bib5","article-title":"Whole-genome sequence, functional annotation, and comparative genomics of the high biofilm-producing multidrug-resistant Pseudomonas aeruginosa MZ4A isolated from clinical waste","volume":"22","author":"Nain","year":"2021","journal-title":"Gene Rep."},{"key":"10.1016\/j.micpath.2025.107634_bib6","doi-asserted-by":"crossref","DOI":"10.5812\/pedinfect.32554","article-title":"Antimicrobial resistance patterns of acinetobacter baumannii, Pseudomonas aeruginosa and Staphylococcus aureus isolated from patients with nosocomial infections admitted to tehran hospitals","volume":"3","author":"Armin","year":"2015","journal-title":"Arch. Pediatr. Infect. Dis."},{"key":"10.1016\/j.micpath.2025.107634_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.diagmicrobio.2021.115568","article-title":"Activity of imipenem-relebactam and ceftolozane-tazobactam against carbapenem-resistant Pseudomonas aeruginosa and KPC-producing Enterobacterales","volume":"102","author":"Bail","year":"2022","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.micpath.2025.107634_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105412","article-title":"A global systematic review and meta-analysis on correlation between biofilm producers and non-biofilm producers with antibiotic resistance in Uropathogenic Escherichia coli","volume":"164","author":"Garousi","year":"2022","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2025.107634_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1374466","article-title":"Antimicrobial resistance of Pseudomonas aeruginosa: navigating clinical impacts, current resistance trends, and innovations in breaking therapies","volume":"15","author":"Elfadadny","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib10","doi-asserted-by":"crossref","first-page":"61","DOI":"10.4103\/abr.abr_37_17","article-title":"Evaluation of biofilm formation and frequency of multidrug-resistant and extended drug-resistant strain in Pseudomonas aeruginosa isolated from burn patients in isfahan","volume":"7","author":"Nasirmoghadas","year":"2018","journal-title":"Adv. Biomed. Res."},{"key":"10.1016\/j.micpath.2025.107634_bib11","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1046\/j.1365-2958.2003.03877.x","article-title":"Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms","volume":"51","author":"Friedman","year":"2004","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.125048","article-title":"Alginate: microbial production, functionalization, and biomedical applications","volume":"242","author":"Wang","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.micpath.2025.107634_bib13","doi-asserted-by":"crossref","first-page":"20983","DOI":"10.3390\/ijms141020983","article-title":"Biofilm matrix and its regulation in Pseudomonas aeruginosa","volume":"14","author":"Wei","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2025.107634_bib14","doi-asserted-by":"crossref","DOI":"10.18502\/ijph.v50i2.5349","article-title":"Evaluation of antibiotic resistance pattern, alginate and biofilm production in clinical isolates of Pseudomonas aeruginosa","author":"Davarzani","year":"2021","journal-title":"Iran. J. Public Health"},{"key":"10.1016\/j.micpath.2025.107634_bib15","doi-asserted-by":"crossref","first-page":"596","DOI":"10.3390\/pathogens3030596","article-title":"Biomolecular mechanisms of Pseudomonas aeruginosa and Escherichia coli biofilm formation","volume":"3","author":"Laverty","year":"2014","journal-title":"Pathogens"},{"key":"10.1016\/j.micpath.2025.107634_bib16","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01010-13","article-title":"Iron-regulated expression of alginate production, mucoid phenotype, and biofilm formation by Pseudomonas aeruginosa","volume":"5","author":"Wiens","year":"2014","journal-title":"mBio"},{"key":"10.1016\/j.micpath.2025.107634_bib17","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/1751-7915.12076","article-title":"Microbial alginate production, modification and its applications","volume":"6","author":"Hay","year":"2013","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.micpath.2025.107634_bib18","author":"Govan"},{"key":"10.1016\/j.micpath.2025.107634_bib19","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jbiotec.2014.09.003","article-title":"Antibiotic resistance in Pseudomonas aeruginosa biofilms: towards the development of novel anti-biofilm therapies","volume":"191","author":"Taylor","year":"2014","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.micpath.2025.107634_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.kjs.2024.100302","article-title":"Identification of algD and oprL genes in Pseudomonas aeruginosa isolated from multiple environments and different local sources in Iraq","volume":"52","author":"Jassim","year":"2025","journal-title":"Kuwait J. Sci."},{"key":"10.1016\/j.micpath.2025.107634_bib21","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/1716087","article-title":"Prevalence of algD , pslD , pelF , ppgl , and PAPI-1 genes involved in biofilm formation in clinical Pseudomonas aeruginosa strains","volume":"2022","author":"Rajabi","year":"2022","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.micpath.2025.107634_bib22","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.3390\/plants12183324","article-title":"Unveiling the potential of algal extracts as promising antibacterial and antibiofilm agents against multidrug-resistant Pseudomonas aeruginosa: in vitro and in silico studies including molecular docking","volume":"12","author":"El-Sapagh","year":"2023","journal-title":"Plants"},{"key":"10.1016\/j.micpath.2025.107634_bib23","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s43556-024-00221-y","article-title":"Multidrug resistance in Pseudomonas aeruginosa: genetic control mechanisms and therapeutic advances","volume":"5","author":"Zhao","year":"2024","journal-title":"Molecular Biomed."},{"key":"10.1016\/j.micpath.2025.107634_bib24","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-28916-7","article-title":"An integrative, multi-omics approach towards the prioritization of Klebsiella pneumoniae drug targets","volume":"8","author":"Ramos","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2025.107634_bib25","doi-asserted-by":"crossref","first-page":"W375","DOI":"10.1093\/nar\/gkm216","article-title":"MolProbity: all-atom contacts and structure validation for proteins and nucleic acids","volume":"35","author":"Davis","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2025.107634_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/07391102.2024.2428825","article-title":"Unraveling the physiochemical characteristics and molecular insights of Zein protein through structural modeling and conformational dynamics: a synergistic approach between machine learning and molecular dynamics simulations","author":"Srivastav","year":"2024","journal-title":"J. Biomol. Struct. Dyn."},{"key":"10.1016\/j.micpath.2025.107634_bib27","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.647060","article-title":"From genome to drugs: new approaches in antimicrobial discovery","volume":"12","author":"Serral","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.micpath.2025.107634_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.nmni.2019.100622","article-title":"Bacterial culture through selective and non-selective conditions: the evolution of culture media in clinical microbiology","volume":"34","author":"Bonnet","year":"2020","journal-title":"New Microbes. New Infect."},{"key":"10.1016\/j.micpath.2025.107634_bib29","doi-asserted-by":"crossref","first-page":"76","DOI":"10.24018\/ejbio.2021.2.5.286","article-title":"Comparison of bis NEG-D and API 20E for the identification of gram-negative bacilli in the laboratory of the university hospital of befelatanana antananarivo Madagascar","volume":"2","author":"Rakotovao-Ravahatra","year":"2021","journal-title":"European J. Biol. Biotechnol."},{"key":"10.1016\/j.micpath.2025.107634_bib30","doi-asserted-by":"crossref","DOI":"10.1177\/0300060521989893","article-title":"Performance of TDR-300B and VITEK\u00ae2 for the identification of Pseudomonas aeruginosa in comparison with VITEK\u00ae-MS","volume":"49","author":"Moehario","year":"2021","journal-title":"J. Int. Med. Res."},{"key":"10.1016\/j.micpath.2025.107634_bib31","author":"James","year":"2023"},{"key":"10.1016\/j.micpath.2025.107634_bib32","doi-asserted-by":"crossref","first-page":"415","DOI":"10.3934\/microbiol.2021025","article-title":"Effect of chitosan nanoparticles on quorum sensing-controlled virulence factors and expression of lasi and rhli genes among pseudomonas aeruginosa clinical isolates","volume":"7","author":"Fattah","year":"2021","journal-title":"AIMS Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib33","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/1471-2180-9-244","article-title":"Comparison of the sensitivity of culture, PCR and quantitative real-time PCR for the detection of Pseudomonas aeruginosain sputum of cystic fibrosis patients","volume":"9","author":"Deschaght","year":"2009","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib34","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1093\/molbev\/msy096","article-title":"Mega X: molecular evolutionary genetics analysis across computing platforms","volume":"35","author":"Kumar","year":"2018","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.micpath.2025.107634_bib35","first-page":"175","author":"Robin","year":"2024","journal-title":"The <scp>SWISS\u2010MODEL<\/scp> Repository of <scp>3D<\/scp> Protein Structures and Models"},{"key":"10.1016\/j.micpath.2025.107634_bib36","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/pro.3330","article-title":"MolProbity: more and better reference data for improved all\u2010atom structure validation","volume":"27","author":"Williams","year":"2018","journal-title":"Protein Sci."},{"key":"10.1016\/j.micpath.2025.107634_bib37","doi-asserted-by":"crossref","first-page":"D564","DOI":"10.1093\/nar\/gky1013","article-title":"Genome properties in 2019: a new companion database to InterPro for the inference of complete functional attributes","volume":"47","author":"Richardson","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2025.107634_bib38","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1128\/JCM.01463-10","article-title":"Matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry as an alternative to 16S rRNA gene sequencing for identification of difficult-to-identify bacterial strains","volume":"49","author":"Bizzini","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib39","doi-asserted-by":"crossref","first-page":"4314","DOI":"10.1128\/JCM.05788-11","article-title":"Species identification of clinical isolates of anaerobic bacteria: a comparison of two matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry systems","volume":"49","author":"Justesen","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib40","first-page":"534","article-title":"Comparative study of MALDI-TOF MS and VITEK 2 in bacteria identification","volume":"6","author":"Guo","year":"2014","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.micpath.2025.107634_bib41","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.3390\/jcm12031189","article-title":"Clinical distribution and drug resistance of Pseudomonas aeruginosa in guangzhou, China from 2017 to 2021","volume":"12","author":"Lyu","year":"2023","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.micpath.2025.107634_bib42","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.2147\/IDR.S402894","article-title":"Epidemiology and multidrug resistance of Pseudomonas aeruginosa and acinetobacter baumanni isolated from clinical samples in Ethiopia","volume":"16","author":"Araya","year":"2023","journal-title":"Infect. Drug Resist."},{"key":"10.1016\/j.micpath.2025.107634_bib43","doi-asserted-by":"crossref","DOI":"10.1186\/s13104-020-4890-z","article-title":"Evaluation of antimicrobial resistance, biofilm forming potential, and the presence of biofilm-related genes among clinical isolates of Pseudomonas aeruginosa","volume":"13","author":"Kamali","year":"2020","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.micpath.2025.107634_bib44","doi-asserted-by":"crossref","DOI":"10.22317\/jcms.v10i3.1557","article-title":"Determine biofilm genes in Pseudomonas aeruginosa isolated from clinical and environmental samples","volume":"10","author":"Al-Mashhadani","year":"2024","journal-title":"J. Contemp. Med. Sci."},{"key":"10.1016\/j.micpath.2025.107634_bib45","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2415-13-57","article-title":"Drug resistance profile and biofilm forming potential of Pseudomonas aeruginosa isolated from contact lenses in Karachi-Pakistan","volume":"13","author":"Abidi","year":"2013","journal-title":"BMC Ophthalmol."},{"key":"10.1016\/j.micpath.2025.107634_bib46","series-title":"Integron Types, Antimicrobial Resistance Genes, Virulence Gene Profile, Alginate Production and Biofilm Formation in Iranian Cystic Fibrosis Pseudomonas aeruginosa Isolates","author":"Pournajaf","year":"2018"},{"key":"10.1016\/j.micpath.2025.107634_bib47","article-title":"Correlation between biofilm formation and multidrug resistance in clinical isolates of Pseudomonas aeruginosa","volume":"0","author":"El-sayed","year":"2021","journal-title":"Microbes. Infect. Dis."},{"key":"10.1016\/j.micpath.2025.107634_bib48","doi-asserted-by":"crossref","first-page":"595","DOI":"10.4103\/MJBL.MJBL_534_23","article-title":"Detection of exopolysaccharides (algD, pelF, and pslD) genes in burn wound Pseudomonas aeruginosa isolates","volume":"20","author":"Alwan","year":"2023","journal-title":"Med. J. Babylon"},{"key":"10.1016\/j.micpath.2025.107634_bib49","doi-asserted-by":"crossref","first-page":"60","DOI":"10.4314\/ajcem.v20i1.9","article-title":"Tube method and Congo red agar versus tissue culture plate method for detection of biofilm production by uropathogens isolated from midstream urine: which one could be better?","volume":"20","author":"Sultan","year":"2018","journal-title":"Afr. J. Clin. Exp. Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib50","doi-asserted-by":"crossref","DOI":"10.5812\/jjm.118452","article-title":"Prevalence of virulence genes and drug resistance profiles of Pseudomonas aeruginosa isolated from clinical specimens","volume":"14","author":"Bazghandi","year":"2021","journal-title":"Jundishapur J. Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0164622","article-title":"Evaluation of mannosidase and trypsin enzymes effects on biofilm production of Pseudomonas aeruginosa isolated from burn wound infections","volume":"11","author":"Banar","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2025.107634_bib52","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jab.2014.05.002","article-title":"The prevalence of some Pseudomonas virulence genes related to biofilm formation and alginate production among clinical isolates","volume":"13","author":"Ghadaksaz","year":"2015","journal-title":"J. Appl. Biomed."},{"key":"10.1016\/j.micpath.2025.107634_bib53","unstructured":"A.O. Namuq, K.O.M. Ali, A.H. Al-Ani, Correlation between Biofilm Formation, Multi-Drug Resistance and AlgD Gene Among Pseudomonas aeruginosa Clinical Isolates, n.d."},{"key":"10.1016\/j.micpath.2025.107634_bib54","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/1716087","article-title":"Prevalence of algD , pslD , pelF , ppgl , and PAPI-1 genes involved in biofilm formation in clinical Pseudomonas aeruginosa strains","volume":"2022","author":"Rajabi","year":"2022","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.micpath.2025.107634_bib55","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3390\/pathogens12010064","article-title":"Antimicrobial resistance and genetic diversity of Pseudomonas aeruginosa strains isolated from equine and other veterinary samples","volume":"12","author":"Pottier","year":"2022","journal-title":"Pathogens"},{"key":"10.1016\/j.micpath.2025.107634_bib56","doi-asserted-by":"crossref","DOI":"10.1002\/pro.4328","article-title":"The roles of highly conserved, non\u2010catalytic residues in class A \u03b2\u2010lactamases","volume":"31","author":"Chikunova","year":"2022","journal-title":"Protein Sci."},{"key":"10.1016\/j.micpath.2025.107634_bib57","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1128\/MMBR.00055-15","article-title":"Bacterial transcription as a target for antibacterial drug development","volume":"80","author":"Ma","year":"2016","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.micpath.2025.107634_bib58","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01252-23","article-title":"Variable region sequences influence 16S rRNA performance","volume":"11","author":"Bose","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.micpath.2025.107634_bib59","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.resmic.2005.06.012","article-title":"Identification of an HptB-mediated multi-step phosphorelay in Pseudomonas aeruginosa PAO1","volume":"157","author":"Lin","year":"2006","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.micpath.2025.107634_bib60","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3390\/toxins16060271","article-title":"Phylogenetic tracing of evolutionarily conserved zonula occludens toxin reveals a \u201chigh value\u201d vaccine candidate specific for treating multi-strain Pseudomonas aeruginosa infections","volume":"16","author":"Benyamini","year":"2024","journal-title":"Toxins"},{"key":"10.1016\/j.micpath.2025.107634_bib61","doi-asserted-by":"crossref","first-page":"W296","DOI":"10.1093\/nar\/gky427","article-title":"SWISS-MODEL: homology modelling of protein structures and complexes","volume":"46","author":"Waterhouse","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2025.107634_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.jksus.2024.103552","article-title":"Copper and chromium binding by Pseudomonas aeruginosa strain PA01 for implications of heavy metal detoxification and soil remediation: a computational approach","volume":"36","author":"Ramasamy","year":"2024","journal-title":"J. King Saud Univ. Sci."},{"key":"10.1016\/j.micpath.2025.107634_bib63","doi-asserted-by":"crossref","DOI":"10.1093\/femsre\/fuad054","article-title":"Structural analysis of novel drug targets for mitigation of Pseudomonas aeruginosa biofilms","volume":"47","author":"Ghosh","year":"2023","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.micpath.2025.107634_bib64","series-title":"Biomolecular Forms and Functions","first-page":"62","article-title":"The ramachandran plot and protein structure validation","author":"Laskowski","year":"2013"},{"key":"10.1016\/j.micpath.2025.107634_bib65","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbae401","article-title":"A computational approach to developing a multi-epitope vaccine for combating Pseudomonas aeruginosa \u2013induced pneumonia and sepsis","volume":"25","author":"Roy","year":"2024","journal-title":"Briefings Bioinf."},{"key":"10.1016\/j.micpath.2025.107634_bib66","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/1787485","article-title":"Targeting essential hypothetical proteins of Pseudomonas aeruginosa PAO1 for mining of novel therapeutics: an in silico approach","volume":"2023","author":"Rahman","year":"2023","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.micpath.2025.107634_bib67","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1009171","article-title":"Protein domain-based prediction of drug\/compound\u2013target interactions and experimental validation on LIM kinases","volume":"17","author":"Do\u011fan","year":"2021","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.micpath.2025.107634_bib68","doi-asserted-by":"crossref","first-page":"942","DOI":"10.3390\/ph15080942","article-title":"Antibiotics and carbohydrate-containing drugs targeting bacterial cell envelopes: an overview","volume":"15","author":"Riu","year":"2022","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.micpath.2025.107634_bib69","doi-asserted-by":"crossref","first-page":"3086","DOI":"10.1021\/acschembio.0c00426","article-title":"Inhibition of the GDP- <scp>d<\/scp> -mannose dehydrogenase from Pseudomonas aeruginosa using targeted sugar nucleotide probes","volume":"15","author":"Beswick","year":"2020","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.micpath.2025.107634_bib70","doi-asserted-by":"crossref","DOI":"10.1093\/femsre\/fuad060","article-title":"Pseudomonas aeruginosa biofilm exopolysaccharides: assembly, function, and degradation","volume":"47","author":"Gheorghita","year":"2023","journal-title":"FEMS Microbiol. Rev."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401025003596?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401025003596?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T03:02:50Z","timestamp":1762311770000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401025003596"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":70,"alternative-id":["S0882401025003596"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107634","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular and computational insights into algD biofilm genes in multi drug resistant and extensively drug resistant Pseudomonas aeruginosa","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107634","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107634"}}