{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T01:09:09Z","timestamp":1778548149563,"version":"3.51.4"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006396","name":"Qazvin University of Medical Sciences","doi-asserted-by":"publisher","award":["400000531"],"award-info":[{"award-number":["400000531"]}],"id":[{"id":"10.13039\/501100006396","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006396","name":"Qazvin University of Medical Sciences","doi-asserted-by":"publisher","award":["28\/20\/21967"],"award-info":[{"award-number":["28\/20\/21967"]}],"id":[{"id":"10.13039\/501100006396","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.micpath.2025.107814","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T11:41:58Z","timestamp":1750333318000},"page":"107814","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["In silico and experimental analysis of ribosomal proteins expressions in SARS-cov-2 patients"],"prefix":"10.1016","volume":"206","author":[{"given":"Farnaz","family":"Vafanezhad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiva Ansari","family":"Astaneh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Rashvand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nematollah","family":"Gheibi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyyed Reza","family":"Mousavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4373-5042","authenticated-orcid":false,"given":"Ali","family":"Abdi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azam Janati","family":"Esfahani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1998-7824","authenticated-orcid":false,"given":"Hossein","family":"Ahmadpour-Yazdi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9147-4962","authenticated-orcid":false,"given":"Hajie","family":"Lotfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2025.107814_bib1","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1128\/CMR.00102-14","article-title":"Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease","volume":"28","author":"Chan","year":"2015","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.micpath.2025.107814_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2020.104793","article-title":"Remdesivir and SARS-CoV-2: structural requirements at both nsp12 RdRp and nsp14 exonuclease active-sites","volume":"178","author":"Shannon","year":"2020","journal-title":"Antivir. Res."},{"key":"10.1016\/j.micpath.2025.107814_bib3","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.apsb.2020.04.007","article-title":"Dose selection of chloroquine phosphate for treatment of COVID-19 based on a physiologically based pharmacokinetic model","volume":"10","author":"Cui","year":"2020","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.micpath.2025.107814_bib4","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1111\/febs.13756","article-title":"Structural domains within the HIV\u20101 mRNA and the ribosomal protein S25 influence cap\u2010independent translation initiation","volume":"283","author":"Carvajal","year":"2016","journal-title":"FEBS J."},{"key":"10.1016\/j.micpath.2025.107814_bib5","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1093\/nar\/gkl155","article-title":"Proteins surrounding hairpin IIIe of the hepatitis C virus internal ribosome entry site on the human 40S ribosomal subunit","volume":"34","author":"Laletina","year":"2006","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2025.107814_bib6","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1128\/MCB.00879-12","article-title":"Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting","volume":"33","author":"Hertz","year":"2013","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.micpath.2025.107814_bib7","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/0092-8674(93)90257-Q","article-title":"Nonlinear ribosome migration on cauliflower mosaic virus 35S RNA","volume":"73","author":"F\u00fctterer","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.micpath.2025.107814_bib8","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1128\/jvi.50.3.966-969.1984","article-title":"Phosphorylation of the ribosomal protein S6 is elevated in cells transformed by a variety of tumor viruses","volume":"50","author":"Blenis","year":"1984","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2025.107814_bib9","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1128\/jvi.39.2.359-366.1981","article-title":"Phosphorylation of ribosomal proteins in hamster fibroblasts infected with pseudorabies virus or herpes simplex virus","volume":"39","author":"Kennedy","year":"1981","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2025.107814_bib10","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1042\/BJ20140449","article-title":"Ribosomal protein S19-binding domain provides insights into hantavirus nucleocapsid protein-mediated translation initiation mechanism","volume":"464","author":"Ganaie","year":"2014","journal-title":"Biochem. J."},{"key":"10.1016\/j.micpath.2025.107814_bib11","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1074\/mcp.M110.003418","article-title":"Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen","volume":"9","author":"Spurgers","year":"2010","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.micpath.2025.107814_bib12","doi-asserted-by":"crossref","first-page":"4572","DOI":"10.1073\/pnas.93.10.4572","article-title":"Functional interaction and colocalization of the herpes simplex virus 1 major regulatory protein ICP4 with EAP, a nucleolar-ribosomal protein","volume":"93","author":"Leopardi","year":"1996","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.micpath.2025.107814_bib13","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/s004380050575","article-title":"Repression of \u03b2-actin synthesis and persistence of ribosomal protein synthesis after infection of HeLa cells by herpes simplex virus type 1 infection are under translational control","volume":"256","author":"Greco","year":"1997","journal-title":"Mol. Gen. Genet. MGG"},{"key":"10.1016\/j.micpath.2025.107814_bib14","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1099\/0022-1317-78-2-435","article-title":"Persistence of ribosomal protein synthesis after infection of HeLa cells by herpes simplex virus type 1","volume":"78","author":"Simonin","year":"1997","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micpath.2025.107814_bib15","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.virol.2015.11.018","article-title":"Rabies virus phosphoprotein interacts with ribosomal protein L9 and affects rabies virus replication","volume":"488","author":"Li","year":"2016","journal-title":"Virology"},{"key":"10.1016\/j.micpath.2025.107814_bib16","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/1743-422X-9-103","article-title":"The HIV-1 nef protein interacts with two components of the 40S small ribosomal subunit, the RPS10 protein and the 18S rRNA","volume":"9","author":"Abbas","year":"2012","journal-title":"Virol. J."},{"key":"10.1016\/j.micpath.2025.107814_bib17","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1099\/jgv.0.000867","article-title":"uS10, a novel Npro-interacting protein, inhibits classical swine fever virus replication","volume":"98","author":"Lv","year":"2017","journal-title":"The Journal of general virology"},{"key":"10.1016\/j.micpath.2025.107814_bib18","doi-asserted-by":"crossref","first-page":"9100","DOI":"10.1128\/JVI.01129-14","article-title":"Extraribosomal l13a is a specific innate immune factor for antiviral defense","volume":"88","author":"Mazumder","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2025.107814_bib19","first-page":"105","article-title":"Conservation of multifunctional ribosomal protein metallopanstimulin-1 (RPS27) through complex evolution demonstrates its key role in growth regulation in archaea, eukaryotic cells, DNA repair, translation and viral replication","volume":"8","author":"Fernandez-Pol","year":"2011","journal-title":"Cancer genomics amp; proteomics."},{"key":"10.1016\/j.micpath.2025.107814_bib20","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1099\/vir.0.035691-0","article-title":"The HBx protein of hepatitis B virus regulates the expression, intracellular distribution and functions of ribosomal protein S27a","volume":"93","author":"Fatima","year":"2012","journal-title":"The Journal of general virology"},{"key":"10.1016\/j.micpath.2025.107814_bib21","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1073\/pnas.1525444113","article-title":"Ribosome protein L4 is essential for epstein-barr virus nuclear antigen 1 function","volume":"113","author":"Shen","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.micpath.2025.107814_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.mehy.2020.109904","article-title":"Ribosomal proteins as a possible tool for blocking SARS-COV 2 virus replication for a potential prospective treatment","volume":"143","author":"Rofeal","year":"2020","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.micpath.2025.107814_bib23","doi-asserted-by":"crossref","DOI":"10.1186\/cc9259","article-title":"Host adaptive immunity deficiency in severe pandemic influenza","volume":"14","author":"Bermejo-Martin","year":"2010","journal-title":"Crit. Care"},{"key":"10.1016\/j.micpath.2025.107814_bib24","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1471-2172-6-2","article-title":"Expression profile of immune response genes in patients with severe acute respiratory syndrome","volume":"6","author":"Reghunathan","year":"2005","journal-title":"BMC Immunol."},{"key":"10.1016\/j.micpath.2025.107814_bib25","doi-asserted-by":"crossref","first-page":"W191","DOI":"10.1093\/nar\/gkz369","article-title":"G: profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)","volume":"47","author":"Raudvere","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2025.107814_bib26","first-page":"1091","article-title":"ClueGO: a cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks","volume":"25","author":"Bindea","year":"2009","journal-title":"Bioinformatics (Oxford, England)"},{"key":"10.1016\/j.micpath.2025.107814_bib27","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1021\/acs.jproteome.8b00702","article-title":"Cytoscape StringApp: network analysis and visualization of proteomics data","volume":"18","author":"Doncheva","year":"2019","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.micpath.2025.107814_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.genrep.2020.100956","article-title":"Bioinformatics analyses of significant genes, related pathways, and candidate diagnostic biomarkers and molecular targets in SARS-CoV-2\/COVID-19","volume":"21","author":"Vastrad","year":"2020","journal-title":"Gene Reports"},{"key":"10.1016\/j.micpath.2025.107814_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcf.2024.03.006","article-title":"Covid-19 in cystic fibrosis patients compared to the general population: severity and virus-host cell interactions","author":"Ciciriello","year":"2024","journal-title":"J. Cyst. Fibros. : official journal of the European Cystic Fibrosis Society"},{"key":"10.1016\/j.micpath.2025.107814_bib30","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1007\/s00203-020-02094-5","article-title":"Selective regulation in ribosome biogenesis and protein production for efficient viral translation","volume":"203","author":"Dong","year":"2021","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.micpath.2025.107814_bib31","doi-asserted-by":"crossref","first-page":"20824","DOI":"10.1074\/jbc.C100206200","article-title":"Ribosomal protein S5 interacts with the internal ribosomal entry site of hepatitis C virus","volume":"276","author":"Fukushi","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.micpath.2025.107814_bib32","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/s41594-020-0511-8","article-title":"SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation","volume":"27","author":"Schubert","year":"2020","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.micpath.2025.107814_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2021.103525","article-title":"Identification of COVID-19 prognostic markers and therapeutic targets through meta-analysis and validation of omics data from nasopharyngeal samples","volume":"70","author":"Biji","year":"2021","journal-title":"EBioMedicine"},{"key":"10.1016\/j.micpath.2025.107814_bib34","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/s41540-024-00364-2","article-title":"Metacell-based differential expression analysis identifies cell type specific temporal gene response programs in COVID-19 patient PBMCs","volume":"10","author":"O'Leary","year":"2024","journal-title":"NPJ systems biology and applications"},{"key":"10.1016\/j.micpath.2025.107814_bib35","article-title":"Role of ribosomal pathways and comorbidity in COVID-19: insight from SARS-CoV-2 proteins and host proteins interaction network analysis","volume":"10","author":"Khan","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.micpath.2025.107814_bib36","doi-asserted-by":"crossref","DOI":"10.1002\/jmv.28845","article-title":"Multi-omic and comparative analyses revealed monocyte-derived alpha-defensin-1 correlated with COVID-19 severity and inhibited SARS-CoV-2 infection","volume":"95","author":"Qian","year":"2023","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.micpath.2025.107814_bib37","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s12979-024-00426-3","article-title":"Changes in the innate immune response to SARS-CoV-2 with advancing age in humans","volume":"21","author":"Agrawal","year":"2024","journal-title":"Immun. Ageing : I amp; A"},{"key":"10.1016\/j.micpath.2025.107814_bib38","article-title":"Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children","volume":"3","author":"Boribong","year":"2022","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.micpath.2025.107814_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102465","article-title":"Redox imbalance in COVID-19 pathophysiology","volume":"56","author":"Majumder","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.micpath.2025.107814_bib40","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abo6783","article-title":"SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression","volume":"8","author":"Hashimoto","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.micpath.2025.107814_bib41","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.154183","article-title":"Functional reprogramming of monocytes in patients with acute and convalescent severe COVID-19","volume":"7","author":"Brauns","year":"2022","journal-title":"JCI insight"},{"key":"10.1016\/j.micpath.2025.107814_bib42","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1290523","article-title":"Cognition-associated long noncoding RNAs are dysregulated upon severe COVID-19","volume":"15","author":"Lee","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.micpath.2025.107814_bib43","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s40635-020-00361-9","article-title":"Transcriptional profiling of leukocytes in critically ill COVID19 patients: implications for interferon response and coagulation","volume":"8","author":"Gill","year":"2020","journal-title":"Intensive care medicine experimental"},{"key":"10.1016\/j.micpath.2025.107814_bib44","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24032646","article-title":"Transcriptional insights of oxidative stress and extracellular traps in lung tissues of fatal COVID-19 cases","volume":"24","author":"Hosseini","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2025.107814_bib45","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1007\/s10875-023-01459-x","article-title":"Neutrophil activation and immune thrombosis profiles persist in convalescent COVID-19","volume":"43","author":"Hocini","year":"2023","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.micpath.2025.107814_bib46","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s00401-023-02612-x","article-title":"Vagus nerve inflammation contributes to dysautonomia in COVID-19","volume":"146","author":"Woo","year":"2023","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.micpath.2025.107814_bib47","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.cels.2020.10.003","article-title":"Large-scale multi-omic analysis of COVID-19 severity","volume":"12","author":"Overmyer","year":"2021","journal-title":"Cell Syst."},{"key":"10.1016\/j.micpath.2025.107814_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1012368","article-title":"The assembly of neutrophil inflammasomes during COVID-19 is mediated by type I interferons","volume":"20","author":"Cabrera","year":"2024","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.micpath.2025.107814_bib49","article-title":"Upper airway gene expression differentiates COVID-19 from other acute respiratory illnesses and reveals suppression of innate immune responses by SARS-CoV-2","author":"Mick","year":"2020","journal-title":"medRxiv : the preprint server for health sciences"},{"key":"10.1016\/j.micpath.2025.107814_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000849","article-title":"In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age","volume":"18","author":"Lieberman","year":"2020","journal-title":"PLoS Biol."},{"key":"10.1016\/j.micpath.2025.107814_bib51","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1111\/febs.13756","article-title":"Structural domains within the HIV-1 mRNA and the ribosomal protein S25 influence cap-independent translation initiation","volume":"283","author":"Carvajal","year":"2016","journal-title":"FEBS J."},{"key":"10.1016\/j.micpath.2025.107814_bib52","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.virol.2015.05.017","article-title":"Dengue virus NS1 protein interacts with the ribosomal protein RPL18: this interaction is required for viral translation and replication in Huh-7 cells","volume":"484","author":"Cervantes-Salazar","year":"2015","journal-title":"Virology"},{"key":"10.1016\/j.micpath.2025.107814_bib53","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s12860-019-0219-y","article-title":"In silico evidence of de novo interactions between ribosomal and Epstein - barr virus proteins","volume":"20","author":"Sim","year":"2019","journal-title":"BMC molecular and cell biology"},{"key":"10.1016\/j.micpath.2025.107814_bib54","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1074\/mcp.RA117.000364","article-title":"Influenza A virus induces autophagosomal targeting of ribosomal proteins","volume":"17","author":"Becker","year":"2018","journal-title":"Mol. Cell. Proteomics : MCP."},{"key":"10.1016\/j.micpath.2025.107814_bib55","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1007\/s11427-016-0018-0","article-title":"The role of ribosomal proteins in the regulation of cell proliferation, tumorigenesis, and genomic integrity","volume":"59","author":"Xu","year":"2016","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.micpath.2025.107814_bib56","doi-asserted-by":"crossref","first-page":"5491","DOI":"10.1038\/s41467-022-33263-3","article-title":"A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production","volume":"13","author":"Genuth","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.micpath.2025.107814_bib57","article-title":"Ribosomal protein L31 (RPL31) inhibits the proliferation and migration of gastric cancer cells","volume":"9","author":"Wu","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.micpath.2025.107814_bib58","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.716730","article-title":"Ribosome proteins represented by RPL27A mark the development and metastasis of triple-negative breast cancer in mouse and human","volume":"9","author":"Zhao","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.micpath.2025.107814_bib59","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.molcel.2009.03.006","article-title":"How common are extraribosomal functions of ribosomal proteins?","volume":"34","author":"Warner","year":"2009","journal-title":"Mol. Cell"},{"key":"10.1016\/j.micpath.2025.107814_bib60","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.cell.2007.10.009","article-title":"Ribosomal protein S3: a KH domain subunit in NF-\u03baB complexes that mediates selective gene regulation","volume":"131","author":"Wan","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.micpath.2025.107814_bib61","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1186\/s12957-023-03102-w","article-title":"High expression of RPL27A predicts poor prognosis in patients with hepatocellular carcinoma","volume":"21","author":"Xing","year":"2023","journal-title":"World J. Surg. Oncol."},{"key":"10.1016\/j.micpath.2025.107814_bib62","doi-asserted-by":"crossref","first-page":"418","DOI":"10.18632\/oncotarget.6225","article-title":"The ribosomal protein S6 in renal cell carcinoma: functional relevance and potential as biomarker","volume":"7","author":"Knoll","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.micpath.2025.107814_bib63","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.7150\/jca.91759","article-title":"Ribosomal protein L22 like 1: a promising biomarker for lung adenocarcinoma","volume":"15","author":"Wu","year":"2024","journal-title":"J. Cancer"},{"key":"10.1016\/j.micpath.2025.107814_bib64","doi-asserted-by":"crossref","first-page":"12392","DOI":"10.18632\/aging.206096","article-title":"RPL22L1 is a novel biomarker for prognosis and immune infiltration in lung adenocarcinoma, promoting the growth and metastasis of LUAD cells by inhibiting the MDM2\/P53 signaling pathway","volume":"16","author":"Xing","year":"2024","journal-title":"Aging"},{"key":"10.1016\/j.micpath.2025.107814_bib65","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.3390\/cancers12051085","article-title":"Ribosomal protein S27\/Metallopanstimulin-1 (RPS27) in glioma\u2014A new disease biomarker?","volume":"12","author":"Feldheim","year":"2020","journal-title":"Cancers"},{"key":"10.1016\/j.micpath.2025.107814_bib66","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s00441-024-03933-3","article-title":"Single cell transcriptomics profiling of the stromal cells in the pathologic association of ribosomal proteins in the ischemic myocardium and epicardial fat","volume":"399","author":"Thai","year":"2025","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.micpath.2025.107814_bib67","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1126\/science.abc8665","article-title":"Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2","volume":"369","author":"Thoms","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.micpath.2025.107814_bib68","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1038\/s41467-021-23621-y","article-title":"Clinical and molecular characteristics of COVID-19 patients with persistent SARS-CoV-2 infection","volume":"12","author":"Yang","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.micpath.2025.107814_bib69","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1007\/s00203-020-02094-5","article-title":"Selective regulation in ribosome biogenesis and protein production for efficient viral translation","volume":"203","author":"Dong","year":"2021","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.micpath.2025.107814_bib70","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.molcel.2017.05.021","article-title":"Heterogeneous ribosomes preferentially translate distinct subpools of mRNAs genome-wide","volume":"67","author":"Shi","year":"2017","journal-title":"Mol. Cell"},{"key":"10.1016\/j.micpath.2025.107814_bib71","first-page":"105","article-title":"Conservation of multifunctional ribosomal protein Metallopanstimulin-1 (RPS27) through complex evolution demonstrates its key role in growth regulation in <em>Archaea<\/em>, eukaryotic cells, DNA repair, translation and viral replication","volume":"8","author":"Fernandez-Pol","year":"2011","journal-title":"Cancer Genomics - Proteomics."},{"key":"10.1016\/j.micpath.2025.107814_bib72","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.tig.2022.05.009","article-title":"Slippy-sloppy translation: a tale of programmed and induced-ribosomal frameshifting","volume":"38","author":"Champagne","year":"2022","journal-title":"Trends Genet."},{"key":"10.1016\/j.micpath.2025.107814_bib73","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2025546118","article-title":"Preventing translational inhibition from ribosomal protein insufficiency by a Herpes simplex virus-encoded ribosome-associated protein","volume":"118","author":"Vink","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.micpath.2025.107814_bib74","doi-asserted-by":"crossref","DOI":"10.3390\/biom14121565","article-title":"The influence of extra-ribosomal functions of eukaryotic ribosomal proteins on viral infection","volume":"14","author":"Zhao","year":"2024","journal-title":"Biomolecules"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088240102500539X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088240102500539X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:13:24Z","timestamp":1778544804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S088240102500539X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":74,"alternative-id":["S088240102500539X"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107814","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In silico and experimental analysis of ribosomal proteins expressions in SARS-cov-2 patients","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2025.107814","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107814"}}