{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:58:17Z","timestamp":1789041497477,"version":"build-2803163510"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017594","name":"Medical Science and Technology Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2023KY450"],"award-info":[{"award-number":["2023KY450"]}],"id":[{"id":"10.13039\/501100017594","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.micpath.2025.108249","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T07:52:00Z","timestamp":1765957920000},"page":"108249","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Acupuncture treatment May improve the bone metabolism and pathological ossification by regulating the gut microbiota of AS mice"],"prefix":"10.1016","volume":"211","author":[{"given":"Yufang","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuechao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2025.108249_bib1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s11882-014-0489-6","article-title":"Update on ankylosing spondylitis: current concepts in pathogenesis","volume":"15","author":"Smith","year":"2015","journal-title":"Curr. Allergy Asthma Rep."},{"key":"10.1016\/j.micpath.2025.108249_bib2","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S0140-6736(07)60635-7","article-title":"Ankylosing spondylitis","volume":"369","author":"Braun","year":"2007","journal-title":"Lancet."},{"key":"10.1016\/j.micpath.2025.108249_bib3","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1007\/s10067-015-2956-4","article-title":"Ankylosis in ankylosing spondylitis: current concepts","volume":"34","author":"Haroon","year":"2015","journal-title":"Clin. Rheumatol."},{"key":"10.1016\/j.micpath.2025.108249_bib4","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1056\/NEJMra1406182","article-title":"Ankylosing spondylitis and axial spondyloarthritis","volume":"374","author":"Taurog","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.micpath.2025.108249_bib5","first-page":"1635","article-title":"Strain ultrasound elastography in the achilles tendon of ankylosing spondylitis patients treated with Anti-TNF-\u03b1: a preliminary study","volume":"33","author":"Zardi","year":"2019","journal-title":"In vivo (Athens, Greece)"},{"key":"10.1016\/j.micpath.2025.108249_bib6","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1002\/art.23260","article-title":"Critical appraisal of assessment of structural damage in ankylosing spondylitis: implications for treatment outcomes","volume":"58","author":"Sieper","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.micpath.2025.108249_bib7","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1093\/rheumatology\/key382","article-title":"High prevalence of hip involvement and decrease in inflammatory ultrasound lesions during tumour necrosis factor-\u03b1 blocking therapy in ankylosing spondylitis","volume":"58","author":"Wink","year":"2019","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.micpath.2025.108249_bib8","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1002\/art.40468","article-title":"Inflammation intensity-dependent expression of osteoinductive Wnt proteins is critical for ectopic new bone formation in ankylosing spondylitis","volume":"70","author":"Li","year":"2018","journal-title":"Arthritis Rheumatol. (Hoboken, NJ)"},{"key":"10.1016\/j.micpath.2025.108249_bib9","doi-asserted-by":"crossref","DOI":"10.1177\/1559325819901239","article-title":"miR-21 may act as a potential mediator between inflammation and abnormal bone formation in ankylosing spondylitis based on TNF-\u03b1 concentration-dependent manner through the JAK2\/STAT3 pathway","volume":"18","author":"Zou","year":"2020","journal-title":"Dose Response : a publication of International Hormesis Society"},{"key":"10.1016\/j.micpath.2025.108249_bib10","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1002\/cbin.10957","article-title":"Icariin attenuates titanium particle-induced inhibition of osteogenic differentiation and matrix mineralization via miR-21-5p","volume":"42","author":"Lian","year":"2018","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.micpath.2025.108249_bib11","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1177\/1753425919842932","article-title":"Serum miR-21 expression correlates with radiographic progression but also low bone mineral density in patients with ankylosing spondylitis: a cross-sectional study","volume":"25","author":"Zou","year":"2019","journal-title":"Innate Immun."},{"key":"10.1016\/j.micpath.2025.108249_bib12","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/978-1-4419-0298-6_8","article-title":"Bone formation versus bone resorption in ankylosing spondylitis","volume":"649","author":"Schett","year":"2009","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.micpath.2025.108249_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232416045","article-title":"Activating Wnt\/\u03b2-Catenin signaling in osteocytes promotes osteogenic differentiation of BMSCs through BMP-7","volume":"23","author":"Zhang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2025.108249_bib14","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/art.39433","article-title":"Imbalance between bone morphogenetic protein 2 and noggin induces abnormal osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis","volume":"68","author":"Xie","year":"2016","journal-title":"Arthritis Rheumatol. (Hoboken, NJ)"},{"key":"10.1016\/j.micpath.2025.108249_bib15","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1136\/annrheumdis-2011-200216","article-title":"High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis","volume":"71","author":"Heiland","year":"2012","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.micpath.2025.108249_bib16","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1093\/rheumatology\/41.12.1395","article-title":"Comparison of the faecal microflora of patients with ankylosing spondylitis and controls using molecular methods of analysis","volume":"41","author":"Stebbings","year":"2002","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.micpath.2025.108249_bib17","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1002\/art.38967","article-title":"Brief report: intestinal dysbiosis in ankylosing spondylitis","volume":"67","author":"Costello","year":"2015","journal-title":"Arthritis Rheumatol. (Hoboken, NJ)"},{"key":"10.1016\/j.micpath.2025.108249_bib18","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1136\/annrheumdis-2016-211064","article-title":"Faecal microbiota study reveals specific dysbiosis in spondyloarthritis","volume":"76","author":"Breban","year":"2017","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.micpath.2025.108249_bib19","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.semarthrit.2019.05.007","article-title":"A cross talk between dysbiosis and gut-associated immune system governs the development of inflammatory arthropathies","volume":"49","author":"Kalinkovich","year":"2019","journal-title":"Semin. Arthritis Rheum."},{"key":"10.1016\/j.micpath.2025.108249_bib20","doi-asserted-by":"crossref","first-page":"6453","DOI":"10.2147\/JIR.S453638","article-title":"Exploration of potential therapeutic targets of shentong zhuyu decoction for ankylosing spondylitis based on network pharmacology and molecular docking","author":"Xin","year":"2024","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.micpath.2025.108249_bib21","first-page":"72","article-title":"Research progress on traditional Chinese medicine treatment of ankylosing spondylitis","volume":"5","author":"Yu","year":"2023","journal-title":"MEDS Chin. Med."},{"key":"10.1016\/j.micpath.2025.108249_bib22","first-page":"2","article-title":"The efficacy of acupuncture and moxibustion on the pain relief of patients with ankylosing spondylitis at the qibian and wanzhong acupoints","volume":"34","author":"Houxiu","year":"2016","journal-title":"Sichuan Tradition. Chin. Med."},{"key":"10.1016\/j.micpath.2025.108249_bib23","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1172\/JCI1666","article-title":"Arthritis induced by proteoglycan aggrecan G1 domain in BALB\/c mice. Evidence for t cell involvement and the immunosuppressive influence of keratan sulfate on recognition of t and b cell epitopes","volume":"101","author":"Zhang","year":"1998","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.micpath.2025.108249_bib24","article-title":"Indole-3-Acetic acid alters intestinal microbiota and alleviates ankylosing spondylitis in mice","volume":"13","author":"Shen","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.micpath.2025.108249_bib25","series-title":"WHO Standard Acupuncture Point Locations in the Western Pacific Region","year":"2008"},{"key":"10.1016\/j.micpath.2025.108249_bib26","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1172\/JCI23738","article-title":"Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis","volume":"115","author":"Lories","year":"2005","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.micpath.2025.108249_bib27","doi-asserted-by":"crossref","first-page":"6275","DOI":"10.4238\/2013.December.4.15","article-title":"ReSeqTools: an integrated toolkit for large-scale next-generation sequencing based resequencing analysis","volume":"12","author":"He","year":"2013","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.micpath.2025.108249_bib28","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1093\/bioinformatics\/btr507","article-title":"FLASH: fast length adjustment of short reads to improve genome assemblies","volume":"27","author":"Mago\u010d","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.micpath.2025.108249_bib29","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1038\/nmeth.2604","article-title":"UPARSE: highly accurate OTU sequences from microbial amplicon reads","volume":"10","author":"Edgar","year":"2013","journal-title":"Nat. Methods"},{"key":"10.1016\/j.micpath.2025.108249_bib30","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1093\/bioinformatics\/btr381","article-title":"UCHIME improves sensitivity and speed of chimera detection","volume":"27","author":"Edgar","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.micpath.2025.108249_bib31","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1128\/AEM.00062-07","article-title":"Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy","volume":"73","author":"Wang","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2025.108249_bib32","doi-asserted-by":"crossref","first-page":"7537","DOI":"10.1128\/AEM.01541-09","article-title":"Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities","volume":"75","author":"Schloss","year":"2009","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2025.108249_bib33","doi-asserted-by":"crossref","first-page":"8228","DOI":"10.1128\/AEM.71.12.8228-8235.2005","article-title":"UniFrac: a new phylogenetic method for comparing microbial communities","volume":"71","author":"Lozupone","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2025.108249_bib34","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/ismej.2010.133","article-title":"UniFrac: an effective distance metric for microbial community comparison","volume":"5","author":"Lozupone","year":"2011","journal-title":"ISME J."},{"key":"10.1016\/j.micpath.2025.108249_bib35","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1128\/AEM.01996-06","article-title":"Quantitative and qualitative beta diversity measures lead to different insights into factors that structure microbial communities","volume":"73","author":"Lozupone","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2025.108249_bib36","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nmeth.f.303","article-title":"QIIME allows analysis of high-throughput community sequencing data","volume":"7","author":"Caporaso","year":"2010","journal-title":"Nat. Methods"},{"key":"10.1016\/j.micpath.2025.108249_bib37","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s11926-017-0644-x","article-title":"The paradox of bone formation and bone loss in ankylosing spondylitis: evolving new concepts of bone formation and future trends in management","volume":"19","author":"Magrey","year":"2017","journal-title":"Curr. Rheumatol. Rep."},{"key":"10.1016\/j.micpath.2025.108249_bib38","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00393-007-0242-9","article-title":"[Immunopathology of ankylosing spondylitis and other spondyloarthritides]","volume":"67","author":"Appel","year":"2008","journal-title":"Z. Rheumatol."},{"key":"10.1016\/j.micpath.2025.108249_bib39","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s13075-023-03011-z","article-title":"MYC promotes fibroblast osteogenesis by regulating ALP and BMP2 to participate in ectopic ossification of ankylosing spondylitis","volume":"25","author":"Jin","year":"2023","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.micpath.2025.108249_bib40","doi-asserted-by":"crossref","first-page":"913","DOI":"10.3109\/14397595.2015.1029221","article-title":"Upregulation of BMP-2 expression in peripheral blood mononuclear cells by proinflammatory cytokines and radiographic progression in ankylosing spondylitis","volume":"25","author":"Chen","year":"2015","journal-title":"Mod. Rheumatol."},{"key":"10.1016\/j.micpath.2025.108249_bib41","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1093\/labmed\/lmab029","article-title":"Serum IL-6 and TNF-\u03b1 levels are correlated with disease severity in patients with ankylosing spondylitis","volume":"53","author":"Du","year":"2022","journal-title":"Lab. Med."},{"key":"10.1016\/j.micpath.2025.108249_bib42","first-page":"80","article-title":"Correlation of serum IL-6, TNF-\u03b1 levels and disease activity in patients with ankylosing spondylitis","volume":"28","author":"Zhao","year":"2024","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.micpath.2025.108249_bib43","article-title":"The use of TNF-\u03b1 inhibitors in active ankylosing spondylitis treatment","volume":"16","author":"Zouris","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.micpath.2025.108249_bib44","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.3899\/jrheum.130515","article-title":"Higher expression of whole blood microRNA-21 in patients with ankylosing spondylitis associated with programmed cell death 4 mRNA expression and collagen cross-linked C-telopeptide concentration","volume":"41","author":"Huang","year":"2014","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.micpath.2025.108249_bib45","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-80859-4","article-title":"Eucommia ulmoides oliver polysaccharide alleviates glucocorticoid-induced osteoporosis by stimulating bone formation via ERK\/BMP-2\/SMAD signaling","volume":"14","author":"Song","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2025.108249_bib46","first-page":"3281","article-title":"MMP-2 silencing reduces the osteogenic transformation of fibroblasts by inhibiting the activation of the BMP\/Smad pathway in ankylosing spondylitis","volume":"15","author":"Yuan","year":"2018","journal-title":"Oncol. Lett."},{"key":"10.1016\/j.micpath.2025.108249_bib47","doi-asserted-by":"crossref","first-page":"200","DOI":"10.3109\/03008207.2015.1127916","article-title":"Downregulation of dickkopf-1 enhances the proliferation and osteogenic potential of fibroblasts isolated from ankylosing spondylitis patients via the Wnt\/\u03b2-catenin signaling pathway in vitro","volume":"57","author":"Zou","year":"2016","journal-title":"Connect. Tissue Res."},{"key":"10.1016\/j.micpath.2025.108249_bib48","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.reth.2022.06.005","article-title":"Circ_0018168 inhibits the proliferation and osteogenic differentiation of fibroblasts in ankylosing spondylitis via regulating miR-330-3p\/DKK1 axis","volume":"21","author":"Zhao","year":"2022","journal-title":"Regen. Ther."},{"key":"10.1016\/j.micpath.2025.108249_bib49","doi-asserted-by":"crossref","first-page":"965","DOI":"10.3892\/etm.2021.10397","article-title":"Tail suspension delays ectopic ossification in proteoglycan-induced ankylosing spondylitis in mice via miR-103\/DKK1","volume":"22","author":"Zhang","year":"2021","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.micpath.2025.108249_bib50","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.13747","article-title":"Role of Wnt5a in modulation of osteoporotic adipose-derived stem cells and osteogenesis","volume":"58","author":"Liu","year":"2025","journal-title":"Cell Prolif."},{"key":"10.1016\/j.micpath.2025.108249_bib51","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1159\/000495489","article-title":"miR-16-2\u2217 interferes with WNT5A to regulate osteogenesis of mesenchymal stem cells","volume":"51","author":"Duan","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.micpath.2025.108249_bib52","first-page":"4541","article-title":"microRNA-1297 promotes the progression of osteoporosis through regulation of osteogenesis of bone marrow mesenchymal stem cells by targeting WNT5A","volume":"23","author":"Wang","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.micpath.2025.108249_bib53","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1136\/annrheumdis-2012-202925","article-title":"Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation","volume":"73","author":"Ciccia","year":"2014","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.micpath.2025.108249_bib54","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/FPC.0000000000000468","article-title":"Association of anti-TNF-\u03b1 treatment with gut microbiota of patients with ankylosing spondylitis","volume":"32","author":"Dai","year":"2022","journal-title":"Pharmacogenet. Genom."},{"key":"10.1016\/j.micpath.2025.108249_bib55","doi-asserted-by":"crossref","DOI":"10.1002\/mbo3.927","article-title":"Anti-TNF-\u03b1 therapy alters the gut microbiota in proteoglycan-induced ankylosing spondylitis in mice","volume":"8","author":"Liu","year":"2019","journal-title":"Microbiologyopen"},{"key":"10.1016\/j.micpath.2025.108249_bib56","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2024.1376525","article-title":"Gut microbiota dysbiosis in ankylosing spondylitis: a systematic review and meta-analysis","volume":"14","author":"Su","year":"2024","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.micpath.2025.108249_bib57","doi-asserted-by":"crossref","first-page":"7841","DOI":"10.2147\/JIR.S517979","article-title":"Dysbiosis of gut microbiota in ankylosing spondylitis patients","volume":"18","author":"Yang","year":"2025","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.micpath.2025.108249_bib58","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1002\/art.41644","article-title":"Inflammasome activation in ankylosing spondylitis is associated with gut dysbiosis","volume":"73","author":"Guggino","year":"2021","journal-title":"Arthritis Rheumatol. (Hoboken, NJ)"},{"key":"10.1016\/j.micpath.2025.108249_bib59","article-title":"Regulation of gut microflora by Lactobacillus casei zhang attenuates liver injury in mice caused by anti-tuberculosis drugs","volume":"24","author":"Li","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2025.108249_bib60","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1097\/QAD.0b013e3283611816","article-title":"Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection","volume":"27","author":"P\u00e9rez-Santiago","year":"2013","journal-title":"Aids"},{"key":"10.1016\/j.micpath.2025.108249_bib61","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.1039\/C8FO02370K","article-title":"Positive effects of a clostridium butyricum-based compound probiotic on growth performance, immune responses, intestinal morphology, hypothalamic neurotransmitters, and colonic microbiota in weaned piglets","volume":"10","author":"Cao","year":"2019","journal-title":"Food Funct."},{"key":"10.1016\/j.micpath.2025.108249_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2024.127725","article-title":"Effects of intestinal desulfovibrio bacteria on host health and its potential regulatory strategies: a review","volume":"284","author":"Zhou","year":"2024","journal-title":"Microbiol. Res."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088240102500974X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088240102500974X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T18:57:32Z","timestamp":1777575452000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S088240102500974X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":62,"alternative-id":["S088240102500974X"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2025.108249","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acupuncture treatment May improve the bone metabolism and pathological ossification by regulating the gut microbiota of AS mice","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2025.108249","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"108249"}}