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Food Anim. Pract."},{"key":"10.1016\/j.micpath.2026.108451_bib71","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.vetmic.2014.04.018","article-title":"High antibody titres against predicted Mycoplasma surface proteins do not prevent sequestration in infected lung tissue in the course of experimental contagious bovine pleuropneumonia","volume":"172","author":"Schieck","year":"2014","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.micpath.2026.108451_bib72","doi-asserted-by":"crossref","first-page":"5395","DOI":"10.1128\/jb.178.18.5395-5401.1996","article-title":"Phenotypic switching of variable surface lipoproteins in Mycoplasma bovis involves high-frequency chromosomal rearrangements","volume":"178","author":"Lysnyansky","year":"1996","journal-title":"J. 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Bacteriol."},{"key":"10.1016\/j.micpath.2026.108451_bib76","doi-asserted-by":"crossref","first-page":"5698","DOI":"10.1128\/JB.183.19.5698-5708.2001","article-title":"Juxtaposition of an active promoter to vsp genes via site-specific DNA inversions generates antigenic variation in Mycoplasma bovis","volume":"183","author":"Lysnyansky","year":"2001","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.micpath.2026.108451_bib77","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1128\/IAI.70.4.2220-2225.2002","article-title":"Extended repertoire of genes encoding variable surface lipoproteins in Mycoplasma bovis strains","volume":"70","author":"Nussbaum","year":"2002","journal-title":"Infect. 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Rev."},{"key":"10.1016\/j.micpath.2026.108451_bib90","doi-asserted-by":"crossref","first-page":"281","DOI":"10.4142\/jvs.2017.18.S1.281","article-title":"Development and trial of vaccines against brucella","volume":"18","author":"Lalsiamthara","year":"2017","journal-title":"J. Vet. Sci."},{"key":"10.1016\/j.micpath.2026.108451_bib91","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0021-9975(03)00009-4","article-title":"Mycoplasma bovis-associated suppurative otitis media and pneumonia in bull calves","volume":"129","author":"Maeda","year":"2003","journal-title":"J. Comp. 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