{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T18:08:30Z","timestamp":1788631710977,"version":"build-2803163510"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.micpath.2026.108479","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T01:03:16Z","timestamp":1775782996000},"page":"108479","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Mutation-driven mechanisms underlying antibiotic resistance of Helicobacter pylori in Asia: A systematic review and meta-analysis (2000\u20132024)"],"prefix":"10.1016","volume":"216","author":[{"given":"Spriha","family":"Dutta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tilottama","family":"Ganguly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nyna","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arunabh","family":"Dutta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pranav","family":"Vij","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Verma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anup","family":"Som","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1202-4942","authenticated-orcid":false,"given":"Rajashree","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib1","doi-asserted-by":"crossref","DOI":"10.1111\/hel.13057","article-title":"Primary antibiotic resistance of Helicobacter pylori in India over the past two decades: a systematic review","volume":"29","author":"Dutta","year":"2024","journal-title":"Helicobacter"},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib2","doi-asserted-by":"crossref","DOI":"10.1186\/s13643-025-02816-0","article-title":"A scoping review of worldwide guidelines for diagnosis and treatment of Helicobacter pylori infection","volume":"14","author":"Sun","year":"2025","journal-title":"Syst. Rev."},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib3","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1136\/gutjnl-2016-312288","article-title":"Management of Helicobacter pylori infection\u2014the Maastricht V\/Florence consensus report","volume":"66","author":"Malfertheiner","year":"2017","journal-title":"Gut"},{"issue":"2","key":"10.1016\/j.micpath.2026.108479_bib4","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1038\/ajg.2016.563","article-title":"ACG clinical guideline: treatment of Helicobacter pylori infection","volume":"112","author":"Chey","year":"2017","journal-title":"Am. J. Gastroenterol."},{"issue":"8","key":"10.1016\/j.micpath.2026.108479_bib5","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.3390\/diagnostics11081458","article-title":"Current Helicobacter pylori diagnostics","volume":"11","author":"Bordin","year":"2021","journal-title":"Diagnostics (Basel)"},{"issue":"10","key":"10.1016\/j.micpath.2026.108479_bib6","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S2468-1253(17)30219-4","article-title":"Primary antibiotic resistance in Helicobacter pylori in the Asia-Pacific region: a systematic review and meta-analysis","volume":"2","author":"Kuo","year":"2017","journal-title":"Lancet Gastroenterol. Hepatol."},{"issue":"4","key":"10.1016\/j.micpath.2026.108479_bib7","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/apt.13497","article-title":"Review article: the global emergence of Helicobacter pylori antibiotic resistance","volume":"43","author":"Thung","year":"2016","journal-title":"Aliment. Pharmacol. Ther."},{"issue":"11","key":"10.1016\/j.micpath.2026.108479_bib8","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.3390\/jcm8112004","article-title":"High prevalence of antibiotic resistance in Iranian Helicobacter pylori isolates: importance of functional and mutational analysis of resistance genes and virulence genotyping","volume":"8","author":"Farzi","year":"2019","journal-title":"J. Clin. Med."},{"issue":"3","key":"10.1016\/j.micpath.2026.108479_bib9","doi-asserted-by":"crossref","first-page":"816","DOI":"10.3390\/jcm12030816","article-title":"Antibiotic resistance of Helicobacter pylori and related risk factors in Yangzhou, China: a cross-sectional study","volume":"12","author":"Zhang","year":"2023","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.micpath.2026.108479_bib10","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jgar.2016.02.007","article-title":"Low prevalence of clarithromycin-resistant Helicobacter pylori isolates with A2143G point mutation in the 23S rRNA gene in North India","volume":"6","author":"Gehlot","year":"2016","journal-title":"J. Glob. Antimicrob. Resist."},{"key":"10.1016\/j.micpath.2026.108479_bib11","doi-asserted-by":"crossref","first-page":"597","DOI":"10.2147\/IDR.S196452","article-title":"Increase in antibiotic resistant Helicobacter pylori in a university hospital in Japan","volume":"12","author":"Kageyama","year":"2019","journal-title":"Infect. Drug Resist."},{"issue":"7","key":"10.1016\/j.micpath.2026.108479_bib12","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.3390\/microorganisms8071062","article-title":"High antibiotic resistance of Helicobacter pylori and its associated novel gene mutations among the Mongolian population","volume":"8","author":"Azzaya","year":"2020","journal-title":"Microorganisms"},{"issue":"12","key":"10.1016\/j.micpath.2026.108479_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0166199","article-title":"Surveillance of Helicobacter pylori antibiotic susceptibility in Indonesia: different resistance types among regions and with novel genetic mutations","volume":"11","author":"Miftahussurur","year":"2016","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.micpath.2026.108479_bib14","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.3390\/antibiotics11101391","article-title":"Multidrug-resistant Helicobacter pylori strains: a five-year surveillance study and its genome characteristics","volume":"11","author":"Sukri","year":"2022","journal-title":"Antibiotics"},{"issue":"4","key":"10.1016\/j.micpath.2026.108479_bib15","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1053\/j.gastro.2023.12.022","article-title":"Global prevalence of Helicobacter pylori infection and incidence of gastric cancer between 1980 and 2022","volume":"166","author":"Chen","year":"2024","journal-title":"Gastroenterology"},{"issue":"7","key":"10.1016\/j.micpath.2026.108479_bib16","doi-asserted-by":"crossref","first-page":"780.e5","DOI":"10.1016\/j.cmi.2017.11.010","article-title":"Primary antibiotic resistance of Helicobacter pylori in Chinese patients: a multiregion prospective 7-year study","volume":"24","author":"Liu","year":"2018","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.micpath.2026.108479_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1294379","article-title":"Antibiotic resistance of Helicobacter pylori in Nanjing, China: a cross-section study from 2018 to 2023","volume":"13","author":"Wei","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.micpath.2026.108479_bib18","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jgar.2018.09.012","article-title":"Characterisation of point mutations in domain V of the 23S rRNA gene of clinical Helicobacter pylori strains and clarithromycin-resistant phenotype in central Vietnam","volume":"16","author":"Tran","year":"2018","journal-title":"J. Glob. Antimicrob. Resist."},{"issue":"4","key":"10.1016\/j.micpath.2026.108479_bib19","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.diagmicrobio.2013.08.010","article-title":"Nationwide survey of Helicobacter pylori antibiotic resistance in Thailand","volume":"77","author":"Vilaichone","year":"2013","journal-title":"Diagn. Microbiol. Infect. Dis."},{"issue":"11","key":"10.1016\/j.micpath.2026.108479_bib20","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1093\/jac\/dkaa302","article-title":"Mutations of Helicobacter pylori RdxA are mainly related to the phylogenetic origin of the strain and not to metronidazole resistance","volume":"75","author":"Zhang","year":"2020","journal-title":"J. Antimicrob. Chemother."},{"issue":"8","key":"10.1016\/j.micpath.2026.108479_bib21","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1128\/JB.184.8.2131-2140.2002","article-title":"Mutations in the 16S rRNA genes of Helicobacter pylori mediate resistance to tetracycline","volume":"184","author":"Trieber","year":"2002","journal-title":"J. Bacteriol."},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib22","doi-asserted-by":"crossref","DOI":"10.1186\/s13099-019-0305-x","article-title":"High primary resistance to metronidazole and levofloxacin, and a moderate resistance to clarithromycin in Helicobacter pylori isolated from Karnataka patients","volume":"11","author":"Shetty","year":"2019","journal-title":"Gut Pathog."},{"issue":"5","key":"10.1016\/j.micpath.2026.108479_bib23","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/QCO.0000000000000396","article-title":"Antibiotic resistance in Helicobacter pylori","volume":"30","author":"Alba","year":"2017","journal-title":"Curr. Opin. Infect. Dis."},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib24","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jmii.2022.07.006","article-title":"Multiple amino acid substitutions in penicillin-binding protein-1A confer amoxicillin resistance in refractory Helicobacter pylori infection","volume":"56","author":"Kuo","year":"2022","journal-title":"J. Microbiol. Immunol. Infect."},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib25","doi-asserted-by":"crossref","DOI":"10.1186\/s12866-016-0873-6","article-title":"Emerging Helicobacter pylori levofloxacin resistance and novel genetic mutation in Nepal","volume":"16","author":"Miftahussurur","year":"2016","journal-title":"BMC Microbiol."},{"issue":"3","key":"10.1016\/j.micpath.2026.108479_bib26","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.ijantimicag.2014.10.019","article-title":"High rate of levofloxacin resistance in a background of clarithromycin- and metronidazole-resistant Helicobacter pylori in Vietnam","volume":"45","author":"Phan","year":"2014","journal-title":"Int. J. Antimicrob. Agents"},{"issue":"7","key":"10.1016\/j.micpath.2026.108479_bib27","doi-asserted-by":"crossref","first-page":"6665","DOI":"10.3390\/cimb46070397","article-title":"Genetic markers of Helicobacter pylori resistance to clarithromycin and levofloxacin in Moscow, Russia","volume":"46","author":"Bodunova","year":"2024","journal-title":"Curr. Issues Mol. Biol."},{"issue":"4","key":"10.1016\/j.micpath.2026.108479_bib28","doi-asserted-by":"crossref","first-page":"437","DOI":"10.3390\/antibiotics10040437","article-title":"Next generation sequencing for the prediction of the antibiotic resistance in Helicobacter pylori: a literature review","volume":"10","author":"Saracino","year":"2021","journal-title":"Antibiotics (Basel)"},{"issue":"7","key":"10.1016\/j.micpath.2026.108479_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med."},{"issue":"3","key":"10.1016\/j.micpath.2026.108479_bib30","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control. Clin. Trials"},{"issue":"3","key":"10.1016\/j.micpath.2026.108479_bib36","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s12664-010-0034-z","article-title":"Characterization of clarithromycin resistance in isolates of Helicobacter pylori from the UAE","volume":"29","author":"Alfaresi","year":"2010","journal-title":"Indian J. Gastroenterol."},{"issue":"40","key":"10.1016\/j.micpath.2026.108479_bib74","doi-asserted-by":"crossref","DOI":"10.3748\/wjg.v21.i40.11221","article-title":"Diagnosis of Helicobacter pylori infection: current options and developments","volume":"21","author":"Wang","year":"2015","journal-title":"World J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib75","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3390\/microorganisms10010196","article-title":"Next-generation sequencing-based study of Helicobacter pylori isolates from Myanmar and their susceptibility to antibiotics","volume":"10","author":"Subsomwong","year":"2022","journal-title":"Microorganisms"},{"issue":"6","key":"10.1016\/j.micpath.2026.108479_bib32","doi-asserted-by":"crossref","first-page":"858","DOI":"10.3390\/jcm8060858","article-title":"A next-generation sequencing-based approach to identify genetic determinants of antibiotic resistance in Cambodian Helicobacter pylori clinical isolates","volume":"8","author":"Tuan","year":"2019","journal-title":"J. Clin. Med."},{"issue":"2","key":"10.1016\/j.micpath.2026.108479_bib33","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3390\/antibiotics12020279","article-title":"Mutations related to antibiotics resistance in Helicobacter pylori clinical isolates from Bangladesh","volume":"12","author":"Fauzia","year":"2023","journal-title":"Antibiotics"},{"issue":"4","key":"10.1016\/j.micpath.2026.108479_bib34","doi-asserted-by":"crossref","first-page":"748","DOI":"10.3390\/antibiotics12040748","article-title":"Novel mutations conferring amoxicillin resistance in Helicobacter pylori in South Korea","volume":"12","author":"Park","year":"2023","journal-title":"Antibiotics"},{"issue":"6","key":"10.1016\/j.micpath.2026.108479_bib35","doi-asserted-by":"crossref","first-page":"3012","DOI":"10.1128\/AAC.00188-11","article-title":"Enhancement of amoxicillin resistance after unsuccessful Helicobacter pylori eradication","volume":"55","author":"Nishizawa","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib76","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3390\/ijms24010179","article-title":"Usefulness of molecular methods for Helicobacter pylori detection in pediatric patients and their correlation with histopathological Sydney classification","volume":"24","author":"Bogiel","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib77","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.23563","article-title":"Validation of loop\u2010mediated isothermal amplification to detect Helicobacter pylori and 23S rRNA mutations: a prospective, observational clinical cohort study","volume":"35","author":"Park","year":"2020","journal-title":"J. Clin. Lab. Anal."},{"issue":"9","key":"10.1016\/j.micpath.2026.108479_bib78","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.3390\/diagnostics11091538","article-title":"Efficacy of loop-mediated isothermal amplification for H. pylori detection as point-of-care testing by noninvasive sampling","volume":"11","author":"Sohrabi","year":"2021","journal-title":"Diagnostics"},{"key":"10.1016\/j.micpath.2026.108479_bib79","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1198325","article-title":"The Helicobacter pylori single nucleotide polymorphisms SNPs associated with multiple therapy resistance in Colombia","volume":"14","author":"Guzman","year":"2023","journal-title":"Front. Microbiol."},{"issue":"5","key":"10.1016\/j.micpath.2026.108479_bib80","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e26809","article-title":"CRISPR-like sequences association with antibiotic resistance and biofilm formation in Helicobacter pylori clinical isolates","volume":"10","author":"Yousefi","year":"2024","journal-title":"Heliyon"},{"issue":"12","key":"10.1016\/j.micpath.2026.108479_bib81","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.3390\/ph15121498","article-title":"CRISPR-CAS system: a tool to eliminate drug-resistant gram-negative bacteria","volume":"15","author":"Kundar","year":"2022","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.micpath.2026.108479_bib37","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.2147\/IDR.S219069","article-title":"Molecular characterization and prevalence of antibiotic resistance in Helicobacter pylori isolates in Kuala Lumpur, Malaysia","volume":"12","author":"Hanafiah","year":"2019","journal-title":"Infect. Drug Resist."},{"issue":"10","key":"10.1016\/j.micpath.2026.108479_bib38","doi-asserted-by":"crossref","first-page":"723","DOI":"10.3390\/antibiotics9100723","article-title":"Helicobacter pylori primary and secondary genotypic resistance to clarithromycin and levofloxacin detection in stools: a 4-Year scenario in Southern Italy","volume":"9","author":"Losurdo","year":"2020","journal-title":"Antibiotics"},{"issue":"7414","key":"10.1016\/j.micpath.2026.108479_bib42","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"Br. Med. J."},{"issue":"3","key":"10.1016\/j.micpath.2026.108479_bib43","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control. Clin. Trials"},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib39","doi-asserted-by":"crossref","DOI":"10.1186\/s13756-019-0482-x","article-title":"Effective therapeutic regimens in two South Asian countries with high resistance to major Helicobacter pylori antibiotics","volume":"8","author":"Miftahussurur","year":"2019","journal-title":"Antimicrob. Resist. Infect. Control"},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib45","doi-asserted-by":"crossref","DOI":"10.1136\/bmjph-2024-002411","article-title":"Global trends in inappropriate use of antibiotics, 2000\u20132021: scoping review and prevalence estimates","volume":"3","author":"Mulchandani","year":"2025","journal-title":"BMJ Public Health"},{"issue":"1","key":"10.1016\/j.micpath.2026.108479_bib46","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1186\/1471-2458-14-847","article-title":"Self medicated antibiotics in Bangladesh: a cross-sectional health survey conducted in the Rajshahi city","volume":"14","author":"Biswas","year":"2014","journal-title":"BMC Public Health"},{"issue":"5","key":"10.1016\/j.micpath.2026.108479_bib40","doi-asserted-by":"crossref","first-page":"dlac112","DOI":"10.1093\/jacamr\/dlac112","article-title":"Antibiotic consumption in India: geographical variations and temporal changes between 2011 and 2019","volume":"4","author":"Koya","year":"2022","journal-title":"JAC-Antimicrobial Resis."},{"issue":"26","key":"10.1016\/j.micpath.2026.108479_bib44","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000029801","article-title":"Recent trends in the antibiotic resistance of Helicobacter pylori in patients with dyspepsia","volume":"101","author":"Buran","year":"2022","journal-title":"Medicine"},{"issue":"4","key":"10.1016\/j.micpath.2026.108479_bib41","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1053\/j.gastro.2023.12.022","article-title":"Global prevalence of Helicobacter pylori infection and incidence of gastric cancer between 1980 and 2022","volume":"166","author":"Chen","year":"2024","journal-title":"Gastroenterology"},{"key":"10.1016\/j.micpath.2026.108479_bib82","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"Br. Med. J."},{"key":"10.1016\/j.micpath.2026.108479_bib83","doi-asserted-by":"crossref","first-page":"168","DOI":"10.3389\/fcimb.2017.00168","article-title":"Novel and effective therapeutic regimens for Helicobacter pylori in an era of increasing antibiotic resistance","volume":"7","author":"Hu","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026002056?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026002056?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T11:10:18Z","timestamp":1779016218000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401026002056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":55,"alternative-id":["S0882401026002056"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108479","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mutation-driven mechanisms underlying antibiotic resistance of Helicobacter pylori in Asia: A systematic review and meta-analysis (2000\u20132024)","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108479","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"108479"}}