{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T23:18:19Z","timestamp":1783207099529,"version":"3.54.6"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2025ZD01905204"],"award-info":[{"award-number":["2025ZD01905204"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFE0199200"],"award-info":[{"award-number":["2023YFE0199200"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82372263"],"award-info":[{"award-number":["82372263"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.micpath.2026.108521","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T15:01:53Z","timestamp":1777647713000},"page":"108521","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Flagellin pretreatment enhances host early innate immune responses against mycobacterial infection"],"prefix":"10.1016","volume":"216","author":[{"given":"Congyi","family":"Dai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjuan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7308-8942","authenticated-orcid":false,"given":"Bo","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2026.108521_bib1","series-title":"Global Tuberculosis Report 2024","year":"2024"},{"key":"10.1016\/j.micpath.2026.108521_bib2","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1146\/annurev-immunol-093019-010426","article-title":"The innate immune response to Mycobacterium tuberculosis infection","volume":"39","author":"Ravesloot-Ch\u00e1vez","year":"2021","journal-title":"Annu. Rev. Immunol."},{"issue":"Suppl 3","key":"10.1016\/j.micpath.2026.108521_bib3","doi-asserted-by":"crossref","first-page":"S102","DOI":"10.1093\/cid\/civ609","article-title":"Perspectives on advances in tuberculosis diagnostics, drugs, and vaccines","volume":"61","author":"Schito","year":"2015","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.micpath.2026.108521_bib4","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a021196","article-title":"Host-directed therapies for tuberculosis","volume":"5","author":"Tobin","year":"2015","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.micpath.2026.108521_bib5","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.cmi.2023.10.023","article-title":"Tuberculosis prevention: current strategies and future directions","volume":"30","author":"Vasiliu","year":"2024","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.micpath.2026.108521_bib6","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1080\/15548627.2024.2321831","article-title":"TRIM27 elicits protective immunity against tuberculosis by activating TFEB-mediated autophagy flux","volume":"20","author":"Zhao","year":"2024","journal-title":"Autophagy"},{"key":"10.1016\/j.micpath.2026.108521_bib7","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1126\/science.1215584","article-title":"Structural basis of TLR5-flagellin recognition and signaling","volume":"335","author":"Yoon","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.micpath.2026.108521_bib8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s00281-007-0078-z","article-title":"TLR5 and ipaf: dual sensors of bacterial flagellin in the innate immune system","volume":"29","author":"Miao","year":"2007","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.micpath.2026.108521_bib9","doi-asserted-by":"crossref","DOI":"10.3390\/ijms262110295","article-title":"Flagellin as a versatile adjuvant platform: genetic fusion approaches for next-generation vaccines","volume":"26","author":"Mardanova","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2026.108521_bib10","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1093\/jleuko\/qiad030","article-title":"Enhanced TLR5-dependent migration and activation of antigen-loaded airway dendritic cells by flagellin","volume":"113","author":"Li","year":"2023","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.micpath.2026.108521_bib11","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1080\/14760584.2018.1457443","article-title":"Flagellin as a vaccine adjuvant","volume":"17","author":"Cui","year":"2018","journal-title":"Expert Rev. Vaccines"},{"key":"10.1016\/j.micpath.2026.108521_bib12","article-title":"Functional properties of flagellin as a stimulator of innate immunity","volume":"6","author":"Lu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2026.108521_bib13","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.2174\/138945011795677809","article-title":"Host-pathogen interactions made transparent with the zebrafish model","volume":"12","author":"Meijer","year":"2011","journal-title":"Curr. Drug Targets"},{"key":"10.1016\/j.micpath.2026.108521_bib14","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1038\/nprot.2013.068","article-title":"Evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish","volume":"8","author":"Takaki","year":"2013","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.micpath.2026.108521_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112793","article-title":"Cross-organ single-cell transcriptome profiling reveals macrophage and dendritic cell heterogeneity in zebrafish","volume":"42","author":"Zhou","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.micpath.2026.108521_bib16","doi-asserted-by":"crossref","first-page":"25353","DOI":"10.1074\/jbc.M112.349126","article-title":"Live imaging reveals differing roles of macrophages and neutrophils during zebrafish tail fin regeneration","volume":"287","author":"Li","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.micpath.2026.108521_bib17","first-page":"841","article-title":"Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system","volume":"6","author":"van der Vaart","year":"2013","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.micpath.2026.108521_bib18","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.893611","article-title":"Negative regulator Nlrc3-like maintain the balanced innate immune response during mycobacterial infection in zebrafish","volume":"13","author":"Niu","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib19","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/s41421-018-0018-1","article-title":"Sequence determinants of specific pattern-recognition of bacterial ligands by the NAIP-NLRC4 inflammasome","volume":"4","author":"Yang","year":"2018","journal-title":"Cell Discov."},{"key":"10.1016\/j.micpath.2026.108521_bib20","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000351476","article-title":"Flagellins of Salmonella typhi and nonpathogenic Escherichia coli are differentially recognized through the NLRC4 pathway in macrophages","volume":"6","author":"Yang","year":"2014","journal-title":"J. Innate Immun."},{"key":"10.1016\/j.micpath.2026.108521_bib21","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2413946122","article-title":"A granulin-positive macrophage subtype in mycobacterial granulomas alleviates tissue damage by limiting excessive inflammation","volume":"122","author":"Luo","year":"2025","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.micpath.2026.108521_bib22","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.devcel.2018.06.003","article-title":"A rapid method for directed gene knockout for screening in G0 zebrafish","volume":"46","author":"Wu","year":"2018","journal-title":"Dev. Cell"},{"key":"10.1016\/j.micpath.2026.108521_bib23","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s11274-017-2315-5","article-title":"Recombinant flagellin-PAL fusion protein of Legionella pneumophila induced cell-mediated and protective immunity against bacteremia in BALB\/c mice","volume":"33","author":"Mohabati Mobarez","year":"2017","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.micpath.2026.108521_bib24","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3389\/fimmu.2020.00171","article-title":"The TLR5 agonist flagellin shapes phenotypical and functional activation of lung mucosal antigen presenting cells in neonatal mice","volume":"11","author":"Sharma","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib25","doi-asserted-by":"crossref","DOI":"10.1128\/aac.00866-24","article-title":"Targeted delivery of flagellin by nebulization offers optimized respiratory immunity and defense against pneumococcal pneumonia","volume":"68","author":"Baldry","year":"2024","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micpath.2026.108521_bib26","doi-asserted-by":"crossref","first-page":"5650","DOI":"10.1038\/s41467-019-13538-y","article-title":"Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases","volume":"10","author":"Tran","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.micpath.2026.108521_bib27","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1109\/TNB.2019.2946336","article-title":"Oscillation expression of NF- \u03ba B driven by transcription and translation time delays","volume":"19","author":"Liu","year":"2020","journal-title":"IEEE Trans. NanoBioscience"},{"key":"10.1016\/j.micpath.2026.108521_bib28","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/imr.12266","article-title":"Macrophage defense mechanisms against intracellular bacteria","volume":"264","author":"Weiss","year":"2015","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.micpath.2026.108521_bib29","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/6530531","article-title":"Cxcl8b and Cxcr2 regulate neutrophil migration through bloodstream in zebrafish","volume":"2017","author":"Zu\u00f1iga-Traslavi\u00f1a","year":"2017","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.micpath.2026.108521_bib30","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/s41581-022-00633-5","article-title":"Trained immunity - basic concepts and contributions to immunopathology","volume":"19","author":"Ochando","year":"2023","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.micpath.2026.108521_bib31","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1146\/annurev-immunol-102119-073855","article-title":"Trained immunity: reprogramming innate immunity in health and disease","volume":"39","author":"Bekkering","year":"2021","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib32","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1016\/j.devcel.2025.02.001","article-title":"Innate immune training of osteoclastogenesis promotes inflammatory bone loss in mice","volume":"60","author":"Haacke","year":"2025","journal-title":"Dev. Cell"},{"key":"10.1016\/j.micpath.2026.108521_bib33","article-title":"Tissue-resident trained immunity in hepatocytes protects against septic liver injury in zebrafish","volume":"43","author":"Wang","year":"2024","journal-title":"Cell Rep."},{"key":"10.1016\/j.micpath.2026.108521_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2025.115493","article-title":"BCG-trained macrophages couple LDLR upregulation to type I IFN responses and antiviral immunity","volume":"44","author":"Lai","year":"2025","journal-title":"Cell Rep."},{"key":"10.1016\/j.micpath.2026.108521_bib35","doi-asserted-by":"crossref","DOI":"10.1126\/science.1250684","article-title":"mTOR- and HIF-1\u03b1-mediated aerobic glycolysis as metabolic basis for trained immunity","volume":"345","author":"Cheng","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.micpath.2026.108521_bib36","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.immuni.2023.12.005","article-title":"Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity","volume":"57","author":"Moorlag","year":"2024","journal-title":"Immunity"},{"key":"10.1016\/j.micpath.2026.108521_bib37","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1016\/j.celrep.2016.11.011","article-title":"Immunometabolic pathways in BCG-induced trained immunity","volume":"17","author":"Arts","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.micpath.2026.108521_bib38","article-title":"A conserved TLR5 binding and activation hot spot on flagellin","volume":"7","author":"Song","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2026.108521_bib39","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/s41435-025-00357-z","article-title":"The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity","volume":"26","author":"Bigot","year":"2025","journal-title":"Gene Immun."},{"key":"10.1016\/j.micpath.2026.108521_bib40","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/s41467-023-44263-2","article-title":"Mucosal TLR5 activation controls healthspan and longevity","volume":"15","author":"Lim","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.micpath.2026.108521_bib41","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1165\/rcmb.2005-0441OC","article-title":"AsialoGM1 and TLR5 cooperate in flagellin-induced nucleotide signaling to activate Erk1\/2","volume":"34","author":"McNamara","year":"2006","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.micpath.2026.108521_bib42","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.621665","article-title":"Flagellin\/TLR5 stimulate myeloid progenitors to enter lung tissue and to locally differentiate into macrophages","volume":"12","author":"Lei","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib43","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.fsi.2011.10.031","article-title":"Inductive expression of toll-like receptor 5 (TLR5) and associated downstream signaling molecules following ligand exposure and bacterial infection in the Indian major carp, mrigal (Cirrhinus mrigala)","volume":"32","author":"Basu","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib44","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/ptr.7656","article-title":"Effect of curcumin on regulatory B cells in chronic colitis mice involving TLR\/MyD88 signaling pathway","volume":"37","author":"Huang","year":"2023","journal-title":"Phytother Res."},{"key":"10.1016\/j.micpath.2026.108521_bib45","doi-asserted-by":"crossref","first-page":"4349","DOI":"10.4049\/jimmunol.1203266","article-title":"Cxcl8 (IL-8) mediates neutrophil recruitment and behavior in the zebrafish inflammatory response","volume":"190","author":"de Oliveira","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2021.104328","article-title":"N-acetylcholine receptors regulate cytokines expression and neutrophils recruitment via MAPK\/ERK signaling in zebrafish","volume":"128","author":"Zhang","year":"2022","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib47","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/s41536-025-00414-1","article-title":"An NF-kB\/TNF-alpha signalling feedback loop acts to coordinate tissue regeneration and macrophage behaviour in zebrafish","volume":"10","author":"Arkoudi","year":"2025","journal-title":"npj Regen. Med."},{"key":"10.1016\/j.micpath.2026.108521_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1509725","article-title":"SAMHD1 deficiency enhances macrophage-mediated clearance of Salmonella typhimurium via NF-\u03baB activation in zebrafish","volume":"16","author":"Mart\u00ednez-L\u00f3pez","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib49","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1136\/gutjnl-2014-308323","article-title":"TLR-Independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice","volume":"65","author":"Vlantis","year":"2016","journal-title":"Gut"},{"key":"10.1016\/j.micpath.2026.108521_bib50","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/nature10510","article-title":"The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus","volume":"477","author":"Zhao","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.micpath.2026.108521_bib51","article-title":"Tissue-resident trained immunity in hepatocytes protects against septic liver injury in zebrafish","volume":"43","author":"Wang","year":"2024","journal-title":"Cell Rep."},{"key":"10.1016\/j.micpath.2026.108521_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2022.104400","article-title":"Towards a new model of trained immunity: exposure to bacteria and \u03b2-glucan protects larval zebrafish against subsequent infections","volume":"132","author":"Darroch","year":"2022","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib53","doi-asserted-by":"crossref","first-page":"2694","DOI":"10.4049\/jimmunol.2000473","article-title":"Macrophage-derived IL-1\u03b2 regulates emergency myelopoiesis via the NF-\u03baB and C\/ebp\u03b2 in zebrafish","volume":"205","author":"Wei","year":"2020","journal-title":"J. Immunol."},{"key":"10.1016\/j.micpath.2026.108521_bib54","doi-asserted-by":"crossref","first-page":"4670","DOI":"10.1038\/s41467-018-07036-w","article-title":"Dynamic control of proinflammatory cytokines Il-1\u03b2 and Tnf-\u03b1 by macrophages in zebrafish spinal cord regeneration","volume":"9","author":"Tsarouchas","year":"2018","journal-title":"Nat. Commun."},{"issue":"Suppl 5","key":"10.1016\/j.micpath.2026.108521_bib55","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1289\/ehp.97105s51159","article-title":"Cytokines and particle-induced inflammatory cell recruitment","volume":"105","author":"Driscoll","year":"1997","journal-title":"Environ. Health Perspect."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026002470?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026002470?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T22:53:48Z","timestamp":1783205628000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401026002470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":55,"alternative-id":["S0882401026002470"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108521","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Flagellin pretreatment enhances host early innate immune responses against mycobacterial infection","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108521","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108521"}}