{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T11:21:52Z","timestamp":1783164112092,"version":"3.54.6"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFD1601606"],"award-info":[{"award-number":["2022YFD1601606"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009010","name":"Henan Agricultural University","doi-asserted-by":"publisher","award":["30501277"],"award-info":[{"award-number":["30501277"]}],"id":[{"id":"10.13039\/501100009010","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.micpath.2026.108537","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:45:01Z","timestamp":1777941901000},"page":"108537","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Characteristics of bovine enterovirus F in four provinces of China: isolation, pathogenicity and immunogenicity"],"prefix":"10.1016","volume":"216","author":[{"given":"Ying","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan-ang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi-meng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui-qin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan-Lan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Ying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Jie","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2026.108537_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/v16071165","article-title":"Epidemiology of Enterovirus genotypes in Association with human diseases","volume":"16","author":"Xie","year":"2024","journal-title":"Viruses"},{"key":"10.1016\/j.micpath.2026.108537_bib2","article-title":"Identification of a novel enterovirus E isolates HY12 from cattle with severe respiratory and enteric diseases","volume":"9","author":"Zhu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2026.108537_bib3","first-page":"27","article-title":"Isolation and characterization of cytopathogenic enteroviruses from cattle with respiratory disease","volume":"20","author":"Moll","year":"1959","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.micpath.2026.108537_bib4","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12866-016-0923-0","article-title":"Identification of a novel bovine enterovirus possessing highly divergent amino acid sequences in capsid protein","volume":"17","author":"Tsuchiaka","year":"2017","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micpath.2026.108537_bib5","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.1099\/vir.0.80159-0","article-title":"Bovine enterovirus 2: complete genomic sequence and molecular modelling of a reference strain and a wild-type isolate from endemically infected US cattle","volume":"85","author":"Goens","year":"2004","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micpath.2026.108537_bib6","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s00705-006-0838-4","article-title":"Characterisation of two enteroviruses isolated from Australian brushtail possums (Trichosurus vulpecula) in New Zealand","volume":"152","author":"Zheng","year":"2007","journal-title":"Arch. Virol."},{"key":"10.1016\/j.micpath.2026.108537_bib7","doi-asserted-by":"crossref","DOI":"10.1017\/S0950268818003394","article-title":"Detection and molecular characterisation of bovine enterovirus in Brazil: four decades since the first report","volume":"147","author":"Candido","year":"2019","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.micpath.2026.108537_bib8","doi-asserted-by":"crossref","DOI":"10.1128\/genomeA.00620-14","article-title":"Full genome sequence of a bovine enterovirus isolated in China","volume":"2","author":"Peng","year":"2014","journal-title":"Genome Announc."},{"key":"10.1016\/j.micpath.2026.108537_bib9","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1863-2378.2007.01095.x","article-title":"Serological survey of bovine enterovirus type 1 in different mammalian species in Turkey","volume":"55","author":"G\u00fcr","year":"2008","journal-title":"Zoonoses Public Health"},{"key":"10.1016\/j.micpath.2026.108537_bib10","article-title":"Emergence of a recombinant bovine enterovirus in China: insights from phylogenetic and temporal analysis","volume":"15","author":"Feng","year":"2025","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.micpath.2026.108537_bib11","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.03785-22","article-title":"Molecular epidemiology of bovine enteroviruses and genome characterization of two novel bovine Enterovirus strains in Guangxi, China","volume":"11","author":"Luo","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.micpath.2026.108537_bib12","article-title":"Epidemiological survey of calf diarrhea related viruses in several areas of Guangdong Province","volume":"15","author":"Chen","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2026.108537_bib13","first-page":"88","article-title":"Etiological investigation and analysis of yak infection with bovine viral diarrhea virus and bovine enterovirus in Haibei Prefecture, Qinghai Province (2016\u20132017)","author":"Song","year":"2019","journal-title":"Heilongjiang Anim. Sci. Vet. Med."},{"key":"10.1016\/j.micpath.2026.108537_bib14","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1099\/vir.0.81298-0","article-title":"Molecular-based reclassification of the bovine enteroviruses","volume":"87","author":"Zell","year":"2006","journal-title":"J. Gen. Virol."},{"issue":"Pt 9","key":"10.1016\/j.micpath.2026.108537_bib15","doi-asserted-by":"crossref","first-page":"2299","DOI":"10.1099\/0022-1317-80-9-2299","article-title":"Functional features of the bovine enterovirus 5'-non-translated region","volume":"80","author":"Zell","year":"1999","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micpath.2026.108537_bib16","first-page":"43","article-title":"Picornaviruses","volume":"343","author":"Tuthill","year":"2010","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.micpath.2026.108537_bib17","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0168-1702(97)00096-8","article-title":"Application of genome sequence information to the classification of bovine enteroviruses: the importance of 5'- and 3'-nontranslated regions","volume":"51","author":"Zell","year":"1997","journal-title":"Virus Res."},{"key":"10.1016\/j.micpath.2026.108537_bib18","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1099\/jgv.0.000911","article-title":"ICTV virus taxonomy profile: picornaviridae","volume":"98","author":"Zell","year":"2017","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micpath.2026.108537_bib19","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.tvjl.2015.10.011","article-title":"Isolation and molecular characterization of bovine enteroviruses in Egypt","volume":"206","author":"Sobhy","year":"2015","journal-title":"Vet. J."},{"key":"10.1016\/j.micpath.2026.108537_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27175569","article-title":"Antiviral effect of bovine Lactoferrin against Enterovirus E","volume":"27","author":"Wr\u00f3bel","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.micpath.2026.108537_bib21","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1099\/vir.0.041335-0","article-title":"Natural interspecies recombinant bovine\/porcine enterovirus in sheep","volume":"93","author":"Boros","year":"2012","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micpath.2026.108537_bib22","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02800-23","article-title":"Genetic diversity and recombination of bovine enterovirus strains in China","volume":"12","author":"Chang","year":"2024","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.micpath.2026.108537_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0193155","article-title":"A neonatal murine model for evaluation of enterovirus E HY12 virus infection and pathogenicity","volume":"13","author":"Gai","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2026.108537_bib24","doi-asserted-by":"crossref","DOI":"10.3390\/v13112217","article-title":"Isolation and identification of type F bovine enterovirus from clinical cattle with diarrhoea","volume":"13","author":"Ji","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.micpath.2026.108537_bib25","doi-asserted-by":"crossref","first-page":"350","DOI":"10.4062\/biomolther.2023.058","article-title":"A bivalent inactivated vaccine prevents Enterovirus 71 and coxsackievirus A16 infections in the Mongolian gerbil","volume":"31","author":"Yi","year":"2023","journal-title":"Biomol Ther (Seoul)."},{"key":"10.1016\/j.micpath.2026.108537_bib26","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1080\/22221751.2022.2093132","article-title":"Development and evaluation of an inactivated coxsackievirus A16 vaccine in gerbils","volume":"11","author":"Sun","year":"2022","journal-title":"Emerg. Microb. Infect."},{"key":"10.1016\/j.micpath.2026.108537_bib27","first-page":"844","article-title":"Isolation, identification, and complete genome analysis of a bovine enterovirus Beijing strain","volume":"48","author":"Zhang","year":"2018","journal-title":"Chinese Veterinary Science"},{"key":"10.1016\/j.micpath.2026.108537_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.cimid.2023.102009","article-title":"Molecular detection and genetic characteristics of a novel porcine circovirus (porcine circovirus 4) and porcine reproductive and respiratory syndrome virus in Shaanxi and Henan Provinces of China","volume":"98","author":"Chen","year":"2023","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"10.1016\/j.micpath.2026.108537_bib29","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s12985-020-1292-8","article-title":"Characterization of a recombinant pseudorabies virus expressing porcine parvovirus VP2 protein and porcine IL-6","volume":"17","author":"Zheng","year":"2020","journal-title":"Virol. J."},{"key":"10.1016\/j.micpath.2026.108537_bib30","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2021.764982","article-title":"Isolation and phylogenetic analysis of reemerging pseudorabies virus within pig populations in central China during 2012 to 2019","volume":"8","author":"Zheng","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.micpath.2026.108537_bib31","article-title":"Isolation and characterization of a variant psedorabies virus HNXY and construction of rHNXY-\u0394TK\/\u0394gE","volume":"10","author":"Wu","year":"2020","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.micpath.2026.108537_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.cimid.2024.102244","article-title":"Epidemiology and genetic diversity of bocavirus in wild rodents in urban areas of Guangzhou, Southern China","volume":"113","author":"Yao","year":"2024","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"10.1016\/j.micpath.2026.108537_bib33","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/03079457.2023.2279131","article-title":"Development of a unique sandwich enzyme-linked immunosorbent assay based on monoclonal antibodies for the specific detection of the egg drop syndrome virus","volume":"53","author":"Wei","year":"2024","journal-title":"Avian Pathol."},{"key":"10.1016\/j.micpath.2026.108537_bib34","doi-asserted-by":"crossref","first-page":"5723","DOI":"10.1002\/jmv.28048","article-title":"Susceptibility to mice and potential evolutionary characteristics of porcine deltacoronavirus","volume":"94","author":"Zhang","year":"2022","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.micpath.2026.108537_bib35","doi-asserted-by":"crossref","first-page":"3536","DOI":"10.1128\/AEM.71.7.3536-3543.2005","article-title":"Survey of bovine enterovirus in biological and environmental samples by a highly sensitive real-time reverse transcription-PCR","volume":"71","author":"Jim\u00e9nez-Clavero","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2026.108537_bib36","doi-asserted-by":"crossref","DOI":"10.1128\/AEM.02420-18","article-title":"Molecular identification of enteroviruses from cattle and goat feces and environment in Thailand","volume":"85","author":"Income","year":"2019","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.micpath.2026.108537_bib37","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1354\/vp.44-1-110","article-title":"Fatal ulcerative and hemorrhagic typhlocolitis in a pregnant heifer associated with natural bovine enterovirus type-1 infection","volume":"44","author":"Blas-Machado","year":"2007","journal-title":"Vet. Pathol."},{"key":"10.1016\/j.micpath.2026.108537_bib38","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1111\/tbed.13873","article-title":"The nasal viromes of cattle on arrival at western Canadian feedlots and their relationship to development of bovine respiratory disease","volume":"68","author":"Zhang","year":"2021","journal-title":"Transbound. Emerg. Dis."},{"key":"10.1016\/j.micpath.2026.108537_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2023.105543","article-title":"High prevalence of Enterovirus E, Bovine Kobuvirus, and Astrovirus revealed by viral metagenomics in fecal samples from cattle in Central Colombia","volume":"117","author":"Medina","year":"2024","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.micpath.2026.108537_bib40","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02662-21","article-title":"Isolation and identification of two clinical strains of the novel genotype enterovirus E5 in China","volume":"10","author":"Ji","year":"2022","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.micpath.2026.108537_bib41","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02711-25","article-title":"Isolation and identification of a genotype F bovine enterovirus in western China","volume":"14","author":"Xu","year":"2026","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.micpath.2026.108537_bib42","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2022.2147022","article-title":"Humoral and cellular immunogenicity and efficacy of a coxsackievirus A10 vaccine in mice","volume":"12","author":"An","year":"2023","journal-title":"Emerg. Microb. Infect."},{"key":"10.1016\/j.micpath.2026.108537_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.virol.2024.110260","article-title":"Immunogenicity analysis based on VP1 and VP2 proteins of bovine enterovirus","volume":"600","author":"Peng","year":"2024","journal-title":"Virology"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026002639?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026002639?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T11:04:39Z","timestamp":1783163079000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401026002639"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":43,"alternative-id":["S0882401026002639"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108537","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characteristics of bovine enterovirus F in four provinces of China: isolation, pathogenicity and immunogenicity","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108537","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108537"}}