{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T07:13:32Z","timestamp":1783754012039,"version":"3.55.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003093","name":"Ministry of Higher Education, Malaysia","doi-asserted-by":"publisher","award":["5220001"],"award-info":[{"award-number":["5220001"]}],"id":[{"id":"10.13039\/501100003093","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020553","name":"Sri Lanka Council for Agricultural Research Policy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004530","name":"Universiti Putra Malaysia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015515","name":"Ministry of Education Malaysia","doi-asserted-by":"publisher","award":["TRGS\/1\/2019\/ UPM \/02\/5"],"award-info":[{"award-number":["TRGS\/1\/2019\/ UPM \/02\/5"]}],"id":[{"id":"10.13039\/501100015515","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.micpath.2026.108605","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T15:31:51Z","timestamp":1780155111000},"page":"108605","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Palm oil\u2013adjuvanted feed-based vaccination enhances humoral and macrophage responses of marine tilapia (Oreochromis sp.) against Vibrio harveyi and Vibrio alginolyticus"],"prefix":"10.1016","volume":"217","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2982-8579","authenticated-orcid":false,"given":"Tilusha","family":"Manchanayake","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ina Salwany","family":"Md Yasin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7664-9821","authenticated-orcid":false,"given":"Mohammad Noor Azmai","family":"Amal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd","family":"Zamri-Saad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6720-2999","authenticated-orcid":false,"given":"Mohd","family":"Firdaus-Nawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4142-0418","authenticated-orcid":false,"given":"Annas","family":"Salleh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2026.108605_bib1","doi-asserted-by":"crossref","first-page":"10.1128","DOI":"10.1128\/microbiolspec.VE-0005-2014","article-title":"The fish pathogen Vibrio vulnificus biotype 2: epidemiology, phylogeny, and virulence factors involved in warm-water vibriosis","volume":"3","author":"Amaro","year":"2015","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.micpath.2026.108605_bib2","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.3390\/microorganisms11051197","article-title":"Pathogenic and opportunistic Vibrio spp. associated with vibriosis incidences in the Greek aquaculture: the role of Vibrio harveyi as the principal cause of vibriosis","volume":"11","author":"Triga","year":"2023","journal-title":"Microorganisms"},{"key":"10.1016\/j.micpath.2026.108605_bib3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.aquaculture.2019.04.042","article-title":"Costs of management practices of Asian seabass (Lates calcarifer bloch, 1790) cage culture in Malaysia using stochastic model that includes uncertainty in mortality","volume":"510","author":"Nor","year":"2019","journal-title":"Aquaculture"},{"key":"10.1016\/j.micpath.2026.108605_bib4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/aah.10045","article-title":"Vibriosis in fish: a review on disease development and prevention","volume":"31","author":"Ina-Salwany","year":"2019","journal-title":"J. Aquat. Anim. Health"},{"key":"10.1016\/j.micpath.2026.108605_bib5","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.fsi.2013.09.007","article-title":"Vibrio anguillarum bacterin uptake via the gills of Japanese flounder and subsequent immune responses","volume":"35","author":"Kato","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib6","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3354\/dao03435","article-title":"Effects of skin abrasion in immersion challenge with Vibrio harveyi in Asian seabass Lates calcarifer fingerlings","volume":"137","author":"Chin","year":"2020","journal-title":"Dis. Aquat. Org."},{"issue":"1","key":"10.1016\/j.micpath.2026.108605_bib7","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.fsi.2014.06.030","article-title":"Notable mucosal immune responses induced in the intestine of zebrafish (Danio rerio) bath-vaccinated with a live attenuated Vibrio anguillarum vaccine","volume":"40","author":"Liu","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib8","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1111\/j.1365-2761.2010.01184.x","article-title":"Histopathological studies on Vibrio harveyi\u2013infected tiger puffer, Takifugu rubripes (Temminck et Schlegel), cultured in Japan","volume":"33","author":"Mohi","year":"2010","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.micpath.2026.108605_bib9","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/7063186","article-title":"Maternal immunity transfer of zebrafish (Danio rerio) following vaccination with a live-attenuated Vibrio harveyi vaccine","volume":"2023","author":"Muhamad-Sofie","year":"2023","journal-title":"Aquac. Res."},{"key":"10.1016\/j.micpath.2026.108605_bib10","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1111\/jfd.12609","article-title":"Isolation, identification and pathogenicity of Vibrio harveyi, the causal agent of skin ulcer disease in juvenile hybrid groupers Epinephelus fuscoguttatus \u00d7 Epinephelus lanceolatus","volume":"40","author":"Shen","year":"2017","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.micpath.2026.108605_bib11","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.aquaculture.2017.02.005","article-title":"Recovery of Vibrio harveyi from scale drop and muscle necrosis disease in farmed barramundi, Lates calcarifer in Vietnam","volume":"473","author":"Dong","year":"2017","journal-title":"Aquaculture"},{"key":"10.1016\/j.micpath.2026.108605_bib12","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.micres.2009.12.001","article-title":"Identification of Vibrio harveyi as a causative bacterium for a tail rot disease of sea bream Sparus aurata from research hatchery in Malta","volume":"165","author":"Haldar","year":"2010","journal-title":"Microbiol. Res."},{"issue":"1\u20134","key":"10.1016\/j.micpath.2026.108605_bib13","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.aquaculture.2006.06.012","article-title":"Vibrio harveyi and other bacterial pathogens in cultured summer flounder, Paralichthys dentatus","volume":"260","author":"Gauger","year":"2006","journal-title":"Aquaculture"},{"key":"10.1016\/j.micpath.2026.108605_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2019.734210","article-title":"Contrasting outcomes of Vibrio harveyi pathogenicity in gilthead seabream, Sparus aurata and European seabass, Dicentrachus labrax","volume":"511","author":"Firmino","year":"2019","journal-title":"Aquaculture"},{"issue":"1","key":"10.1016\/j.micpath.2026.108605_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12866-019-1624-2","article-title":"Prevalence, antimicrobial susceptibility and plasmid profiling of Vibrio spp. isolated from cultured groupers in peninsular Malaysia","volume":"19","author":"Amalina","year":"2019","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micpath.2026.108605_bib17","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1007\/s10499-025-02026-4","article-title":"A systematic review on the development and efficacy of nano-based vaccine in aquaculture","volume":"33","author":"Ishaq","year":"2025","journal-title":"Aquac. Int."},{"issue":"1","key":"10.1016\/j.micpath.2026.108605_bib18","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3390\/ijms17010040","article-title":"Vaccination of silver sea bream (Sparus sarba) against Vibrio alginolyticus: protective evaluation of different vaccinating modalities","volume":"17","author":"Li","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2026.108605_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2020.736201","article-title":"Impacts of oral Vibrio mimicus double-targeted DNA vaccine on the gut microbiota in grass carps (Ctenopharyngodon idella) and correlations with intestinal mucosa innate immunity","volume":"533","author":"Cao","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.micpath.2026.108605_bib20","doi-asserted-by":"crossref","first-page":"368","DOI":"10.3390\/vaccines9040368","article-title":"Vaccine efficacy of a newly developed feed-based whole-cell polyvalent vaccine against vibriosis, streptococcosis and motile aeromonad septicemia in Asian seabass, Lates calcarifer","volume":"9","author":"Mohamad","year":"2021","journal-title":"Vaccines"},{"issue":"7","key":"10.1016\/j.micpath.2026.108605_bib21","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.3390\/ani11071876","article-title":"Intranasal vaccination strategy to control the COVID-19 pandemic from a veterinary medicine perspective","volume":"11","author":"Salleh","year":"2021","journal-title":"Animals"},{"key":"10.1016\/j.micpath.2026.108605_bib22","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3389\/fimmu.2015.00519","article-title":"Oral vaccination of fish\u2013antigen preparations, uptake, and immune induction","volume":"6","author":"Mutoloki","year":"2015","journal-title":"Front. Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib23","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1016\/j.fsi.2013.02.029","article-title":"Adjuvants and immunostimulants in fish vaccines: current knowledge and future perspectives","volume":"35","author":"Tafalla","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2025.110503","article-title":"Oral adjuvanted vibrio vaccine enhances antibody production and lysozyme activity in the serum and mucus of marine-cultured red hybrid tilapia (Oreochromis sp.) against V. harveyi and V. alginolyticus","author":"Manchanayake","year":"2025","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib25","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1365-2109.2012.03207.x","article-title":"Efficacy of feed-based adjuvant vaccine against Streptococcus agalactiae in Oreochromis spp. in Malaysia","volume":"45","author":"Firdaus-Nawi","year":"2014","journal-title":"Aquac. Res."},{"key":"10.1016\/j.micpath.2026.108605_bib26","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.3389\/fimmu.2019.02225","article-title":"Effects of cell differentiation on the phagocytic activities of IgM+ B cells in a teleost fish","volume":"10","author":"Wu","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib27","doi-asserted-by":"crossref","first-page":"486","DOI":"10.17221\/3294-VETMED","article-title":"Innate and adaptive immunity in teleost fish: a review","volume":"56","author":"Uribe","year":"2011","journal-title":"Vet. Med."},{"key":"10.1016\/j.micpath.2026.108605_bib28","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.fsi.2019.10.006","article-title":"Advances in salmonid fish immunology: a review of methods and techniques for lymphoid tissue and peripheral blood leucocyte isolation and application","volume":"95","author":"Lulijwa","year":"2019","journal-title":"Fish Shellfish Immunol."},{"issue":"3","key":"10.1016\/j.micpath.2026.108605_bib29","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1006\/fsim.2001.0394","article-title":"The professional phagocytes of sea bass (Dicentrarchus labrax L.): cytochemical characterization of neutrophils and macrophages in the normal and inflamed peritoneal cavity","volume":"13","author":"do Vale","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib30","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.dci.2013.08.003","article-title":"Antimicrobial responses of teleost phagocytes and innate immune evasion strategies of intracellular bacteria","volume":"43","author":"Grayfer","year":"2014","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib31","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/j.1365-2958.2011.07612.x","article-title":"How does the oxidative burst of macrophages kill bacteria? Still an open question","volume":"80","author":"Slauch","year":"2011","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.micpath.2026.108605_bib32","doi-asserted-by":"crossref","first-page":"734","DOI":"10.3390\/vaccines8040734","article-title":"Efficacy of whole cell inactivated Vibrio harveyi vaccine against vibriosis in a marine red hybrid tilapia (Oreochromis niloticus x O.mossambicus) model","volume":"8","author":"Abu Nor","year":"2020","journal-title":"Vaccines"},{"key":"10.1016\/j.micpath.2026.108605_bib33","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1007\/s00203-024-04166-2","article-title":"Stability characterizations of feed-based bivalent vaccine containing inactivated Streptococcus agalactiae and Aeromonas hydrophila against streptococcosis and aeromonas infections in red hybrid tilapia (Oreochromis sp.)","volume":"206","author":"Ali","year":"2024","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.micpath.2026.108605_bib34","article-title":"Effects of increasing dietary carbohydrate level on feed utilization, body composition, liver glycogen, and intestinal short chain fatty acids of hybrid lemon fin barb (Barbonymus gonionotus \u2640\u00d7 Hypsibarbus wetmorei male \u2642)","volume":"16","author":"Sulaiman","year":"2020","journal-title":"Aquac. Rep."},{"key":"10.1016\/j.micpath.2026.108605_bib35","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/are.13894","article-title":"Generation of mouse monoclonal antibodies specific to tilapia immunoglobulin using fish immunoglobulin\/BSA complex for monitoring of the immune response in nile tilapia Oreochromis niloticus","volume":"50","author":"Soonthonsrima","year":"2019","journal-title":"Aquac. Res."},{"issue":"1","key":"10.1016\/j.micpath.2026.108605_bib36","first-page":"35","article-title":"In vitro phagocytic study of blood leukocytes and peritoneal macrophages of walking catfish Clarias batrachus against Aeromonas hydrophila and Escherichia coli","volume":"6","author":"Rashid","year":"2002","journal-title":"Bangladesh J. Fish. Res."},{"key":"10.1016\/j.micpath.2026.108605_bib37","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.micpath.2019.04.012","article-title":"In-vitro phagocytosis and intracellular killing of Pasteurella multocida B:2 by phagocytic cells of buffaloes","volume":"131","author":"Puspitasari","year":"2019","journal-title":"Microb. Pathog."},{"issue":"2","key":"10.1016\/j.micpath.2026.108605_bib38","doi-asserted-by":"crossref","first-page":"275","DOI":"10.14202\/vetworld.2022.275-280","article-title":"Phagocytosis and intracellular killing of Pasteurella multocida B: 2 by macrophages: a comparative study between buffalo and cattle","volume":"15","author":"Hasnan","year":"2022","journal-title":"Vet. World"},{"key":"10.1016\/j.micpath.2026.108605_bib39","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.fsi.2021.04.006","article-title":"Immuno-protective efficiency of feed-based whole-cell inactivated bivalent vaccine against Streptococcus and Aeromonas infections in red hybrid tilapia (Oreochromis niloticus \u00d7 Oreochromi mossambicus)","volume":"113","author":"Monir","year":"2021","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.736379","article-title":"Cross-protection of Listonella anguillarum and Vibrio alginolyticus FKC bacterins to control vibriosis in European sea bass (Dicentrarchus labrax)","volume":"535","author":"Diab","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.micpath.2026.108605_bib41","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.fsi.2012.03.032","article-title":"Development and efficacy of an attenuated Vibrio harveyi vaccine candidate with cross protectivity against Vibrio alginolyticus","volume":"32","author":"Hu","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib42","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.fsi.2017.04.008","article-title":"A formalin-inactivated vaccine provides good protection against Vibrio harveyi infection in orange-spotted grouper (Epinephelus coioides)","volume":"65","author":"Nguyen","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib43","series-title":"Fish Vaccines","first-page":"101","article-title":"Role of adjuvants in vaccination studies","author":"Ina-Salwany","year":"2023"},{"key":"10.1016\/j.micpath.2026.108605_bib44","doi-asserted-by":"crossref","DOI":"10.4194\/AQUAST2188","article-title":"Formulation and field evaluation of palm oil adjuvanted feed-based streptococcosis vaccine in cage-cultured red hybrid tilapia","volume":"25","author":"Ridzuan","year":"2025","journal-title":"Aquac. Stud."},{"key":"10.1016\/j.micpath.2026.108605_bib45","doi-asserted-by":"crossref","first-page":"465","DOI":"10.14202\/vetworld.2022.465-482","article-title":"Current status and advances of fish vaccines in Malaysia","volume":"15","author":"Ridzuan","year":"2022","journal-title":"Vet. World"},{"key":"10.1016\/j.micpath.2026.108605_bib46","series-title":"Fish Vaccines","first-page":"113","article-title":"Development of mucosal adjuvants for fish vaccination","author":"Yasin","year":"2023"},{"issue":"9","key":"10.1016\/j.micpath.2026.108605_bib47","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1084\/jem.20022232","article-title":"A role for complement in feedback enhancement of antibody responses by IgG3","volume":"197","author":"Diaz de Stahl","year":"2003","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.micpath.2026.108605_bib48","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.3389\/fmicb.2017.02638","article-title":"Bactericidal properties of channel catfish peritoneal macrophages exposed to Edwardsiella ictaluri live attenuated vaccine and wild-type strains","volume":"8","author":"Kordon","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2026.108605_bib49","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.dci.2009.05.009","article-title":"Identification of phagocytic cells, NK-like cytotoxic cell activity and the production of cellular exudates in the coelomic cavity of adult zebrafish","volume":"33","author":"Moss","year":"2009","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib50","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3390\/vaccines10020207","article-title":"Protective efficacy of novel oral biofilm vaccines against Photobacterium damselae subsp. damselae infection in giant grouper, Epinephelus lanceolatus","volume":"10","author":"Su","year":"2022","journal-title":"Vaccines"},{"key":"10.1016\/j.micpath.2026.108605_bib51","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.dci.2016.07.016","article-title":"Leukocyte susceptibility and immune response against Vibrio parahaemolyticus in Totoaba macdonaldi","volume":"65","author":"Reyes-Becerril","year":"2016","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.micpath.2026.108605_bib52","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.fsi.2007.11.001","article-title":"Comparison of the responses of peritoneal macrophages from Japanese flounder (Paralichthys olivaceus) against high virulent and low virulent strains of Edwardsiella tarda","volume":"24","author":"Ishibe","year":"2008","journal-title":"Fish Shellfish Immunol."},{"issue":"8","key":"10.1016\/j.micpath.2026.108605_bib53","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1016\/j.molimm.2006.09.022","article-title":"The activation of gilthead seabream professional phagocytes by different PAMPs underlines the behavioural diversity of the main innate immune cells of bony fish","volume":"44","author":"Sepulcre","year":"2007","journal-title":"Mol. Immunol."},{"issue":"2","key":"10.1016\/j.micpath.2026.108605_bib54","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1348-0421.2001.tb01281.x","article-title":"Identification and characterization of the sodA genes encoding manganese superoxide dismutases in Vibrio parahaemolyticus, Vibrio mimicus, and Vibrio vulnificus","volume":"45","author":"Kimoto","year":"2001","journal-title":"Microbiol. Immunol."},{"issue":"1","key":"10.1016\/j.micpath.2026.108605_bib55","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1080\/22221751.2020.1720526","article-title":"Vibrio pore-forming leucocidin activates pyroptotic cell death via the NLRP3 inflammasome","volume":"9","author":"Cohen","year":"2020","journal-title":"Emerg. Microb. Infect."},{"key":"10.1016\/j.micpath.2026.108605_bib56","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.micpath.2015.08.009","article-title":"Comparative clinicopathological changes in buffalo and cattle following infection by Pasteurella multocida B:2","volume":"88","author":"Annas","year":"2015","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2026.108605_bib57","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0009-8981(02)00180-8","article-title":"Initial responses to endotoxins and Gram-negative bacteria","volume":"323","author":"Heumann","year":"2002","journal-title":"Clin. Chim. Acta"},{"issue":"34","key":"10.1016\/j.micpath.2026.108605_bib58","doi-asserted-by":"crossref","first-page":"12497","DOI":"10.1073\/pnas.0802773105","article-title":"Vibrio parahaemolyticus orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, and then cell lysis","volume":"10","author":"Burdette","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.micpath.2026.108605_bib59","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1099\/mic.0.040626-0","article-title":"The type III secretion system of Vibrio alginolyticus induces rapid apoptosis, cell rounding and osmotic lysis of fish cells","volume":"156","author":"Zhao","year":"2010","journal-title":"Microbiology"},{"key":"10.1016\/j.micpath.2026.108605_bib60","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.gene.2018.06.029","article-title":"KatG plays an important role in Aeromonas hydrophila survival in fish macrophages and escape for further infection","volume":"672","author":"Zhang","year":"2018","journal-title":"Gene"},{"key":"10.1016\/j.micpath.2026.108605_bib61","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3389\/fimmu.2019.00042","article-title":"Trained innate immunity of fish is a viable approach in larval aquaculture","volume":"10","author":"Zhang","year":"2019","journal-title":"Front. Immunol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026003311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026003311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T06:34:18Z","timestamp":1783751658000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401026003311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":60,"alternative-id":["S0882401026003311"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108605","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Palm oil\u2013adjuvanted feed-based vaccination enhances humoral and macrophage responses of marine tilapia (Oreochromis sp.) against Vibrio harveyi and Vibrio alginolyticus","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108605","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108605"}}