{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T04:02:40Z","timestamp":1793505760619,"version":"4.5.0"},"reference-count":88,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001407","name":"India Ministry of Science &amp; Technology Department of Biotechnology","doi-asserted-by":"publisher","award":["BT \/PR41246\/ NER \/95\/1685\/2020"],"award-info":[{"award-number":["BT \/PR41246\/ NER \/95\/1685\/2020"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.micpath.2026.108669","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T15:35:22Z","timestamp":1782747322000},"page":"108669","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Aptamer-mediated inhibition of cellular apoptosis and ROS induced by the p54 protein of African swine fever virus"],"prefix":"10.1016","volume":"218","author":[{"given":"Nilave Ranjan","family":"Bora","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushil","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachin","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micpath.2026.108669_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.virusres.2020.198099","article-title":"African swine fever - a review of current knowledge","volume":"287","author":"Blome","year":"2020","journal-title":"Virus Res."},{"key":"10.1016\/j.micpath.2026.108669_bib2","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1038\/s43016-021-00362-1","article-title":"African swine fever outbreaks in China led to gross domestic product and economic losses","volume":"2","author":"You","year":"2021","journal-title":"Nat. Food"},{"key":"10.1016\/j.micpath.2026.108669_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105561","article-title":"African swine fever virus: a raised global upsurge and a continuous threaten to pig husbandry","volume":"167","author":"Ata","year":"2022","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.micpath.2026.108669_bib4","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1098\/rstb.2009.0098","article-title":"African swine fever: how can global spread be prevented?","volume":"364","author":"Costard","year":"2009","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.micpath.2026.108669_bib5","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1111\/tbed.12527","article-title":"Update on the risk of introduction of African swine fever by wild boar into disease-free European union countries","volume":"64","author":"Bosch","year":"2017","journal-title":"Transbound. Emerg. Dis."},{"key":"10.1016\/j.micpath.2026.108669_bib6","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1515\/jvetres-2017-0055","article-title":"African swine fever (ASF) and ticks. No risk of tick-mediated ASF spread in Poland and Baltic states","volume":"61","author":"Frant","year":"2017","journal-title":"J Vet Res"},{"key":"10.1016\/j.micpath.2026.108669_bib7","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.virusres.2012.12.007","article-title":"African swine fever in the north caucasus region and the Russian Federation in years 2007-2012","volume":"173","author":"Gogin","year":"2013","journal-title":"Virus Res."},{"key":"10.1016\/j.micpath.2026.108669_bib8","doi-asserted-by":"crossref","first-page":"796","DOI":"10.3201\/eid2404.171238","article-title":"African swine fever virus, Siberia, Russia, 2017","volume":"24","author":"Kolbasov","year":"2018","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.micpath.2026.108669_bib9","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.3201\/eid2411.181274","article-title":"Molecular characterization of African swine fever virus, China, 2018","volume":"24","author":"Ge","year":"2018","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.micpath.2026.108669_bib10","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/tbed.13483","article-title":"Outbreak of African swine fever in South Korea, 2019","volume":"67","author":"Kim","year":"2020","journal-title":"Transbound. Emerg. Dis."},{"key":"10.1016\/j.micpath.2026.108669_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/01652176.2023.2178689","article-title":"Transmission of African swine fever virus to the wild boars of Northeast India","volume":"43","author":"Buragohain","year":"2023","journal-title":"Vet. Q."},{"key":"10.1016\/j.micpath.2026.108669_bib12","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.antiviral.2019.02.018","article-title":"African swine fever","volume":"165","author":"Dixon","year":"2019","journal-title":"Antivir. Res."},{"key":"10.1016\/j.micpath.2026.108669_bib13","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.virusres.2012.10.030","article-title":"Epidemiology of African swine fever virus","volume":"173","author":"Costard","year":"2013","journal-title":"Virus Res."},{"key":"10.1016\/j.micpath.2026.108669_bib14","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1099\/vir.0.83343-0","article-title":"Comparison of the genome sequences of non-pathogenic and pathogenic African swine fever virus isolates","volume":"89","author":"Chapman","year":"2008","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micpath.2026.108669_bib15","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.virusres.2012.10.020","article-title":"African swine fever virus replication and genomics","volume":"173","author":"Dixon","year":"2013","journal-title":"Virus Res."},{"key":"10.1016\/j.micpath.2026.108669_bib16","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1006\/viro.1995.1149","article-title":"Analysis of the complete nucleotide sequence of African swine fever virus","volume":"208","author":"Yanez","year":"1995","journal-title":"Virology"},{"key":"10.1016\/j.micpath.2026.108669_bib17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1515\/jvetres-2017-0017","article-title":"Roles of African swine fever virus structural proteins in viral infection","volume":"61","author":"Jia","year":"2017","journal-title":"J Vet Res"},{"key":"10.1016\/j.micpath.2026.108669_bib18","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.virusres.2012.09.016","article-title":"African swine fever virus morphogenesis","volume":"173","author":"Salas","year":"2013","journal-title":"Virus Res."},{"key":"10.1016\/j.micpath.2026.108669_bib19","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1128\/JCM.00406-06","article-title":"Optimization and validation of recombinant serological tests for African swine fever diagnosis based on detection of the p30 protein produced in trichoplusia ni larvae","volume":"44","author":"Perez-Filgueira","year":"2006","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.micpath.2026.108669_bib20","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3390\/v9090241","article-title":"Investigations of Pro- and anti-apoptotic factors affecting African swine fever virus replication and pathogenesis","volume":"9","author":"Dixon","year":"2017","journal-title":"Viruses"},{"key":"10.1016\/j.micpath.2026.108669_bib21","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.febslet.2004.06.001","article-title":"The African swine fever virus dynein-binding protein p54 induces infected cell apoptosis","volume":"569","author":"Hernaez","year":"2004","journal-title":"FEBS Lett."},{"key":"10.1016\/j.micpath.2026.108669_bib22","article-title":"The role of oxidative stress in the pathogenesis of infections with coronaviruses","volume":"13","author":"Gain","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.micpath.2026.108669_bib23","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/j.bcp.2006.04.011","article-title":"NF-kappaB activation by reactive oxygen species: fifteen years later","volume":"72","author":"Gloire","year":"2006","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.micpath.2026.108669_bib24","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1096\/fasebj.11.2.9039953","article-title":"An essential role for free radicals and derived species in signal transduction","volume":"11","author":"Lander","year":"1997","journal-title":"FASEB J."},{"key":"10.1016\/j.micpath.2026.108669_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.mehy.2020.110102","article-title":"SARS-CoV-2 infection pathogenesis is related to oxidative stress as a response to aggression","volume":"143","author":"Cecchini","year":"2020","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.micpath.2026.108669_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3390\/v8010013","article-title":"The influenza virus H5N1 infection can induce ROS production for viral replication and host cell death in A549 cells modulated by human Cu\/Zn superoxide dismutase (SOD1) overexpression","volume":"8","author":"Lin","year":"2016","journal-title":"Viruses"},{"key":"10.1016\/j.micpath.2026.108669_bib27","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.3390\/v14102170","article-title":"Development of an effective double antigen sandwich ELISA based on p30 protein to detect antibodies against African swine fever virus","volume":"14","author":"Wang","year":"2022","journal-title":"Viruses"},{"key":"10.1016\/j.micpath.2026.108669_bib28","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/s41419-023-05749-5","article-title":"Influenza viral matrix 1 protein aggravates viral pathogenicity by inducing TLR4-mediated reactive oxygen species production and apoptotic cell death","volume":"14","author":"Kim","year":"2023","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.micpath.2026.108669_bib29","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1111\/irv.12067","article-title":"Oxygen free radical involvement in acute lung injury induced by H5N1 virus in mice","volume":"7","author":"He","year":"2013","journal-title":"Influenza Other Respir Viruses"},{"key":"10.1016\/j.micpath.2026.108669_bib30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002250","article-title":"HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6","volume":"7","author":"Gonzalez-Dosal","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.micpath.2026.108669_bib31","doi-asserted-by":"crossref","first-page":"439","DOI":"10.3390\/v5020439","article-title":"HCV and oxidative stress in the liver","volume":"5","author":"Ivanov","year":"2013","journal-title":"Viruses"},{"key":"10.1016\/j.micpath.2026.108669_bib32","doi-asserted-by":"crossref","first-page":"37481","DOI":"10.1074\/jbc.M506412200","article-title":"Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production","volume":"280","author":"Korenaga","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.micpath.2026.108669_bib33","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.42448","article-title":"Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production","volume":"8","author":"Hu","year":"2019","journal-title":"eLife"},{"key":"10.1016\/j.micpath.2026.108669_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0113234","article-title":"Enterovirus 71 induces mitochondrial reactive oxygen species generation that is required for efficient replication","volume":"9","author":"Cheng","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2026.108669_bib35","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.tim.2021.12.011","article-title":"Mitochondria-mediated oxidative stress during viral infection","volume":"30","author":"Foo","year":"2022","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.micpath.2026.108669_bib36","doi-asserted-by":"crossref","first-page":"9788","DOI":"10.1073\/pnas.0703584104","article-title":"Newcastle disease virus, a host range-restricted virus, as a vaccine vector for intranasal immunization against emerging pathogens","volume":"104","author":"DiNapoli","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.micpath.2026.108669_bib37","doi-asserted-by":"crossref","first-page":"10054","DOI":"10.1128\/JVI.78.18.10054-10063.2004","article-title":"A recombinant newcastle disease virus (NDV) expressing VP2 protein of infectious bursal disease virus (IBDV) protects against NDV and IBDV","volume":"78","author":"Huang","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2026.108669_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.virol.2025.110477","article-title":"Development of an apoptotic lentogenic Newcastle disease virus strain by incorporating the p30 protein of African swine fever virus","volume":"606","author":"Bora","year":"2025","journal-title":"Virology"},{"key":"10.1016\/j.micpath.2026.108669_bib39","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.imlet.2014.02.009","article-title":"Genetically engineered Newcastle disease virus expressing interleukin 2 is a potential drug candidate for cancer immunotherapy","volume":"159","author":"Bai","year":"2014","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.micpath.2026.108669_bib40","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1038\/sj.gt.3303026","article-title":"Recombinant newcastle disease virus (NDV) with inserted gene coding for GM-CSF as a new vector for cancer immunogene therapy","volume":"14","author":"Janke","year":"2007","journal-title":"Gene Ther."},{"key":"10.1016\/j.micpath.2026.108669_bib41","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1007\/s00705-019-04425-4","article-title":"Evaluation of surface glycoproteins of classical swine fever virus as immunogens and reagents for serological diagnosis of infections in pigs: a recombinant Newcastle disease virus approach","volume":"164","author":"Kumar","year":"2019","journal-title":"Arch. Virol."},{"key":"10.1016\/j.micpath.2026.108669_bib42","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1016\/j.vaccine.2019.11.088","article-title":"Evaluation of Japanese encephalitis virus E and NS1 proteins immunogenicity using a recombinant Newcastle disease virus in mice","volume":"38","author":"Nath","year":"2020","journal-title":"Vaccine"},{"key":"10.1016\/j.micpath.2026.108669_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.103132","article-title":"Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate","volume":"62","author":"Sun","year":"2020","journal-title":"EBioMedicine"},{"key":"10.1016\/j.micpath.2026.108669_bib44","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/978-1-0716-1888-2_4","article-title":"Reverse genetics and its usage in the development of vaccine against poultry diseases","volume":"2411","author":"Nath","year":"2022","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.micpath.2026.108669_bib45","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1093\/ps\/82.6.899","article-title":"Recombinant Newcastle disease virus as a vaccine vector","volume":"82","author":"Huang","year":"2003","journal-title":"Poult. Sci."},{"key":"10.1016\/j.micpath.2026.108669_bib46","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1021\/acsptsci.2c00156","article-title":"Therapeutic potential of aptamer-protein interactions","volume":"5","author":"Shraim","year":"2022","journal-title":"ACS Pharmacol. Transl. Sci."},{"key":"10.1016\/j.micpath.2026.108669_bib47","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0024071","article-title":"A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death","volume":"6","author":"Esposito","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2026.108669_bib48","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1016\/j.bbrc.2005.10.172","article-title":"In vitro selection of DNA aptamers binding ethanolamine","volume":"338","author":"Mann","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.micpath.2026.108669_bib49","doi-asserted-by":"crossref","first-page":"4229","DOI":"10.3390\/molecules24234229","article-title":"Aptamers: a review of their chemical properties and modifications for therapeutic application","volume":"24","author":"Adachi","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.micpath.2026.108669_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2025.116577","article-title":"Paper-based electrochemical aptasensor functionalized with zinc oxide nanorods for rapid and sensitive detection of Newcastle disease virus","volume":"220","author":"Kumar","year":"2026","journal-title":"Microchem. J."},{"key":"10.1016\/j.micpath.2026.108669_bib51","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1126\/science.2200121","article-title":"Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase","volume":"249","author":"Tuerk","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.micpath.2026.108669_bib52","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1038\/346818a0","article-title":"In vitro selection of RNA molecules that bind specific ligands","volume":"346","author":"Ellington","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.micpath.2026.108669_bib53","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.coph.2007.12.005","article-title":"Aptamers as candidate therapeutics for cardiovascular indications","volume":"8","author":"Keefe","year":"2008","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.micpath.2026.108669_bib54","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1365-2443.2012.01596.x","article-title":"RNA plasticity and selectivity applicable to therapeutics and novel biosensor development","volume":"17","author":"Nakamura","year":"2012","journal-title":"Genes Cells"},{"key":"10.1016\/j.micpath.2026.108669_bib55","doi-asserted-by":"crossref","first-page":"9123","DOI":"10.3390\/ijms21239123","article-title":"Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy","volume":"21","author":"Fu","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.micpath.2026.108669_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2020.112210","article-title":"An antibody-aptamer sandwich cathodic photoelectrochemical biosensor for the detection of progesterone","volume":"160","author":"Zhu","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.micpath.2026.108669_bib57","doi-asserted-by":"crossref","first-page":"4078","DOI":"10.1038\/s41598-024-53619-7","article-title":"In vitro SELEX and application of an African swine fever virus (ASFV) p30 protein specific aptamer","volume":"14","author":"Hu","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micpath.2026.108669_bib58","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/nrd3141","article-title":"Aptamers as therapeutics","volume":"9","author":"Keefe","year":"2010","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.micpath.2026.108669_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2025.127964","article-title":"Screening of aptamer for p30 protein of African swine fever virus and establishment of electrochemical immunosensor for detection of p30 antibody","volume":"292","author":"Huang","year":"2025","journal-title":"Talanta"},{"key":"10.1016\/j.micpath.2026.108669_bib60","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0076-6879(00)26058-8","article-title":"Purification of proteins using polyhistidine affinity tags","volume":"326","author":"Bornhorst","year":"2000","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.micpath.2026.108669_bib61","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/BF00228148","article-title":"AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR","volume":"8","author":"Laskowski","year":"1996","journal-title":"J. Biomol. NMR"},{"key":"10.1016\/j.micpath.2026.108669_bib62","doi-asserted-by":"crossref","first-page":"W407","DOI":"10.1093\/nar\/gkm290","article-title":"ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins","volume":"35","author":"Wiederstein","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2026.108669_bib63","doi-asserted-by":"crossref","first-page":"W365","DOI":"10.1093\/nar\/gkx407","article-title":"HDOCK: a web server for protein-protein and protein-DNA\/RNA docking based on a hybrid strategy","volume":"45","author":"Yan","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.micpath.2026.108669_bib64","doi-asserted-by":"crossref","DOI":"10.1128\/mra.00227-22","article-title":"Draft genome sequence analysis of the genotype II African swine fever virus from India","volume":"11","author":"Buragohain","year":"2022","journal-title":"Microbiol. Resour. Announc."},{"key":"10.1016\/j.micpath.2026.108669_bib65","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jcpa.2004.11.004","article-title":"Proinflammatory cytokines induce lymphocyte apoptosis in acute African swine fever infection","volume":"132","author":"Salguero","year":"2005","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.micpath.2026.108669_bib66","first-page":"77","article-title":"Apoptosis of thymocytes in experimental African swine fever virus infection","volume":"19","author":"Salguero","year":"2004","journal-title":"Histol. Histopathol."},{"issue":"Pt 6","key":"10.1016\/j.micpath.2026.108669_bib67","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1099\/0022-1317-79-6-1427","article-title":"African swine fever: a disease characterized by apoptosis","volume":"79","author":"Oura","year":"1998","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.micpath.2026.108669_bib68","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0165-2427(02)00225-8","article-title":"Changes in macrophages in spleen and lymph nodes during acute African swine fever: expression of cytokines","volume":"90","author":"Salguero","year":"2002","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.micpath.2026.108669_bib69","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.rvsc.2006.11.011","article-title":"An immunohistochemical study of the tonsils in pigs with acute African swine fever virus infection","volume":"83","author":"Fernandez de Marco","year":"2007","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.micpath.2026.108669_bib70","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1128\/JVI.73.3.2173-2180.1999","article-title":"African swine fever virus infection induces tumor necrosis factor alpha production: implications in pathogenesis","volume":"73","author":"Gomez del Moral","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2026.108669_bib71","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3390\/v15010233","article-title":"African swine fever virus infection and cytokine response in vivo: an update","volume":"15","author":"Franzoni","year":"2023","journal-title":"Viruses"},{"key":"10.1016\/j.micpath.2026.108669_bib72","doi-asserted-by":"crossref","first-page":"10514","DOI":"10.1128\/JVI.00485-06","article-title":"Macrophage transcriptional responses following in vitro infection with a highly virulent African swine fever virus isolate","volume":"80","author":"Zhang","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2026.108669_bib73","doi-asserted-by":"crossref","first-page":"282","DOI":"10.3389\/fvets.2020.00282","article-title":"Comparative pathology and pathogenesis of African swine fever infection in swine","volume":"7","author":"Salguero","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.micpath.2026.108669_bib74","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/jmv.26232","article-title":"The cytokine storm and COVID-19","volume":"93","author":"Hu","year":"2021","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.micpath.2026.108669_bib75","doi-asserted-by":"crossref","DOI":"10.1080\/21505594.2024.2375550","article-title":"Pathogenicity and virulence of African swine fever virus","volume":"15","author":"Ruedas-Torres","year":"2024","journal-title":"Virulence"},{"key":"10.1016\/j.micpath.2026.108669_bib76","doi-asserted-by":"crossref","first-page":"7480","DOI":"10.1080\/07391102.2022.2123400","article-title":"Computational analysis of immunogenic epitopes in the p30 and p54 proteins of African swine fever virus","volume":"41","author":"Imdhiyas","year":"2023","journal-title":"J. Biomol. Struct. Dyn."},{"key":"10.1016\/j.micpath.2026.108669_bib77","doi-asserted-by":"crossref","first-page":"9819","DOI":"10.1128\/JVI.75.20.9819-9827.2001","article-title":"African swine fever virus protein p54 interacts with the microtubular motor complex through direct binding to light-chain dynein","volume":"75","author":"Alonso","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2026.108669_bib78","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1038\/nprot.2006.238","article-title":"Analysis of apoptosis by propidium iodide staining and flow cytometry","volume":"1","author":"Riccardi","year":"2006","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.micpath.2026.108669_bib79","article-title":"Detection of total reactive oxygen species in adherent cells by 2',7'-Dichlorodihydrofluorescein diacetate staining","author":"Kim","year":"2020","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.micpath.2026.108669_bib80","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1023\/A:1022945107762","article-title":"The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update","volume":"8","author":"Ly","year":"2003","journal-title":"Apoptosis"},{"key":"10.1016\/j.micpath.2026.108669_bib81","doi-asserted-by":"crossref","DOI":"10.21769\/BioProtoc.3128","article-title":"Analysis of the mitochondrial membrane potential using the cationic JC-1 dye as a sensitive fluorescent probe","volume":"9","author":"Sivandzade","year":"2019","journal-title":"Bio Protoc"},{"key":"10.1016\/j.micpath.2026.108669_bib82","first-page":"361","article-title":"MitoSOX-Based flow cytometry for detecting mitochondrial ROS","volume":"2","author":"Kauffman","year":"2016","journal-title":"React Oxyg Species (Apex)"},{"key":"10.1016\/j.micpath.2026.108669_bib83","doi-asserted-by":"crossref","first-page":"5689","DOI":"10.1128\/jvi.70.8.5689-5694.1996","article-title":"Neutralizing antibodies to different proteins of African swine fever virus inhibit both virus attachment and internalization","volume":"70","author":"Gomez-Puertas","year":"1996","journal-title":"J. Virol."},{"key":"10.1016\/j.micpath.2026.108669_bib84","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.2147\/IJN.S237544","article-title":"Aptamers as versatile ligands for biomedical and pharmaceutical applications","volume":"15","author":"Guan","year":"2020","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.micpath.2026.108669_bib85","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/978-1-4939-9179-2_9","article-title":"ITC measurement for high-affinity aptamers binding to their target proteins","volume":"1964","author":"Amano","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.micpath.2026.108669_bib86","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2021.122971","article-title":"Assays to estimate the binding affinity of aptamers","volume":"238","author":"Thevendran","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.micpath.2026.108669_bib87","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.biochi.2017.10.010","article-title":"Thermodynamic study of aptamers binding to their target proteins","volume":"145","author":"Sakamoto","year":"2018","journal-title":"Biochimie"},{"key":"10.1016\/j.micpath.2026.108669_bib88","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3390\/v13122490","article-title":"The A179L gene of African swine fever virus suppresses virus-induced apoptosis but enhances necroptosis","volume":"13","author":"Shi","year":"2021","journal-title":"Viruses"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026003955?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026003955?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T20:38:21Z","timestamp":1785875901000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401026003955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":88,"alternative-id":["S0882401026003955"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108669","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aptamer-mediated inhibition of cellular apoptosis and ROS induced by the p54 protein of African swine fever virus","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108669","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108669"}}