{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:50:33Z","timestamp":1791834633485,"version":"4.3.4"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82360189"],"award-info":[{"award-number":["82360189"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.micpath.2026.108869","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:30:22Z","timestamp":1791387022000},"page":"108869","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Phage-antibiotic synergy dismantles multidrug-resistant Enterococcus faecalis infection in SD rat apical periodontitis model"],"prefix":"10.1016","volume":"221","author":[{"given":"Yingying","family":"Xiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wengong","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingling","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolian","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingting","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kehui","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1421-8049","authenticated-orcid":false,"given":"Xiuling","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.micpath.2026.108869_bib1","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/iej.13467","article-title":"The global prevalence of apical periodontitis: a systematic review and meta-analysis","volume":"54","author":"Tib\u00farcio-Machado","year":"2021","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib2","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/prd.12631","article-title":"The role of the oral microbiome, host response, and periodontal disease treatment in alzheimer's disease: a primer","volume":"98","author":"Chalmers","year":"2025","journal-title":"Periodontol. 2000"},{"issue":"2","key":"10.1016\/j.micpath.2026.108869_bib3","doi-asserted-by":"crossref","first-page":"540","DOI":"10.3390\/jcm9020540","article-title":"Apical periodontitis and diabetes mellitus type 2: a systematic review and meta-analysis","volume":"9","author":"P\u00e9rez-Losada","year":"2020","journal-title":"J. Clin. Med."},{"issue":"8","key":"10.1016\/j.micpath.2026.108869_bib4","first-page":"1039","article-title":"Update on bacterial nosocomial infections","volume":"16","author":"Bereket","year":"2012","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"10","key":"10.1016\/j.micpath.2026.108869_bib5","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1080\/23744235.2024.2379492","article-title":"Phage therapy: an alternative treatment modality for MDR bacterial infections","volume":"56","author":"Pal","year":"2024","journal-title":"Infect. Dis. (Lond.)"},{"issue":"8","key":"10.1016\/j.micpath.2026.108869_bib6","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.1128\/AEM.00096-15","article-title":"Targeting Enterococcus faecalis biofilms with phage therapy","volume":"81","author":"Khalifa","year":"2015","journal-title":"Appl. Environ. Microbiol."},{"issue":"8","key":"10.1016\/j.micpath.2026.108869_bib7","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1093\/cid\/ciad335","article-title":"A retrospective, observational study of 12 cases of expanded-access customized phage therapy: production, characteristics, and clinical outcomes","volume":"77","author":"Green","year":"2023","journal-title":"Clin. Infect. Dis."},{"issue":"10","key":"10.1016\/j.micpath.2026.108869_bib50","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.3390\/v13101898","article-title":"A case of in situ phage therapy against Staphylococcus aureus in a bone allograft polymicrobial biofilm infection: outcomes and phage-antibiotic interactions","volume":"13","author":"Van Nieuwenhuyse","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.micpath.2026.108869_bib8","doi-asserted-by":"crossref","first-page":"e144","DOI":"10.1093\/cid\/ciaa705","article-title":"Phage therapy for limb-threatening prosthetic knee Klebsiella pneumoniae infection: case report and in vitro characterization of anti-biofilm activity","volume":"3","author":"Cano","year":"2021","journal-title":"Clin. Infect. Dis."},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib9","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1038\/s41467-025-68136-y","article-title":"Timely bespoke phage-antibiotic combination to treat refractory Pseudomonas aeruginosa mediastinitis and vascular graft infection","volume":"17","author":"Chung","year":"2026","journal-title":"Nat. Commun."},{"issue":"10","key":"10.1016\/j.micpath.2026.108869_bib10","doi-asserted-by":"crossref","first-page":"954","DOI":"10.3390\/v11100954","article-title":"Eradication of vancomycin-resistant Enterococci by combining phage and vancomycin","volume":"11","author":"Shlezinger","year":"2019","journal-title":"Viruses"},{"key":"10.1016\/j.micpath.2026.108869_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.698807","article-title":"Characterization of an Enterococcus faecalis bacteriophage vB_EfaM_LG1 and its synergistic effect with antibiotic","volume":"11","author":"Song","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib12","doi-asserted-by":"crossref","DOI":"10.1111\/1751-7915.70075","article-title":"From isolation to application: utilising phage-antibiotic synergy in murine bacteremia model to combat multidrug-resistant Enterococcus faecalis","volume":"18","author":"Yehia","year":"2025","journal-title":"Microb. Biotechnol."},{"issue":"8","key":"10.1016\/j.micpath.2026.108869_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0000799","article-title":"Phage-antibiotic synergy (PAS): beta-lactam and quinolone antibiotics stimulate virulent phage growth","volume":"2","author":"Comeau","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.micpath.2026.108869_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2024.1433313","article-title":"Strategies and mechanisms targeting Enterococcus faecalis biofilms associated with endodontic infections: a comprehensive review","volume":"14","author":"Yang","year":"2024","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib14","doi-asserted-by":"crossref","DOI":"10.1080\/20002297.2026.2687225","article-title":"Combined treatment with bacteriophages and sodium hypochlorite against E. faecalis biofilm in an in vitro root canal model with evaluation of bacterial resistance","volume":"18","author":"Steffen","year":"2026","journal-title":"J. Oral Microbiol."},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib15","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12941-025-00790-y","article-title":"Novel strategies for vancomycin-resistant Enterococcus faecalis biofilm control: bacteriophage (vB_EfaS_ZC1), propolis, and their combined effects in an ex vivo endodontic model","volume":"24","author":"Hakim","year":"2025","journal-title":"Ann. Clin. Microbiol. Antimicrob."},{"issue":"7","key":"10.1016\/j.micpath.2026.108869_bib16","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.3390\/v13071268","article-title":"The safety and toxicity of phage therapy: a review of animal and clinical studies","volume":"13","author":"Liu","year":"2021","journal-title":"Viruses"},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib17","doi-asserted-by":"crossref","first-page":"162","DOI":"10.3390\/ph19010162","article-title":"Phage therapy at the crossroads between clinical promise and regulatory challenge","volume":"19","author":"Gallina","year":"2026","journal-title":"Pharmaceuticals"},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib18","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s12903-024-05399-9","article-title":"Phage therapy as an alternative strategy for oral bacterial infections: a systematic review","volume":"25","author":"Zhu","year":"2025","journal-title":"BMC Oral Health"},{"issue":"5\u20136","key":"10.1016\/j.micpath.2026.108869_bib51","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1007\/s00253-022-11810-8","article-title":"Phage therapy for refractory periapical periodontitis caused by Enterococcus faecalis in vitro and in vivo","volume":"106","author":"Xiang","year":"2022","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"9","key":"10.1016\/j.micpath.2026.108869_bib19","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1139\/cjm-2019-0336","article-title":"Biological characteristics and whole-genome analysis of the Enterococcus faecalis phage PEf771","volume":"66","author":"Xiang","year":"2020","journal-title":"Can. J. Microbiol."},{"issue":"9","key":"10.1016\/j.micpath.2026.108869_bib20","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.3390\/pharmaceutics14091779","article-title":"In vitro evaluation of five newly isolated bacteriophages against E. faecalis biofilm for their potential use against post-treatment apical periodontitis","volume":"14","author":"Voit","year":"2022","journal-title":"Pharmaceutics"},{"issue":"3","key":"10.1016\/j.micpath.2026.108869_bib21","doi-asserted-by":"crossref","first-page":"517","DOI":"10.3390\/microorganisms9030517","article-title":"Bacteriophages to control multi-drug resistant Enterococcus faecalis infection of dental root canals","volume":"9","author":"El-Telbany","year":"2021","journal-title":"Microorganisms"},{"key":"10.1016\/j.micpath.2026.108869_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.104045","article-title":"Phage-antibiotic combination is a superior treatment against Acinetobacter baumannii in a preclinical study","volume":"80","author":"Gordillo Altamirano","year":"2022","journal-title":"EBioMedicine"},{"issue":"2","key":"10.1016\/j.micpath.2026.108869_bib23","doi-asserted-by":"crossref","DOI":"10.1128\/aac.00740-24","article-title":"In vitro resensitization of multidrug-resistant clinical isolates of Enterococcus faecium and E. faecalis through phage-antibiotic synergy","volume":"69","author":"Ghatbale","year":"2025","journal-title":"Antimicrob Agents Ch"},{"issue":"22","key":"10.1016\/j.micpath.2026.108869_bib24","first-page":"358","article-title":"SOS response and its regulation on the fluoroquinolone resistance","volume":"3","author":"Qin","year":"2015","journal-title":"Ann. Transl. Med."},{"issue":"7","key":"10.1016\/j.micpath.2026.108869_bib25","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/nrmicro3270","article-title":"Microbiological effects of sublethal levels of antibiotics","volume":"12","author":"Andersson","year":"2014","journal-title":"Nat. Rev. Microbiol."},{"issue":"9","key":"10.1016\/j.micpath.2026.108869_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011602","article-title":"Phage-antibiotic synergy: cell filamentation is a key driver of successful phage predation","volume":"19","author":"Bulssico","year":"2023","journal-title":"PLoS Pathog."},{"issue":"4","key":"10.1016\/j.micpath.2026.108869_bib27","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.joen.2011.12.020","article-title":"Treatment of root canal biofilms of Enterococcus faecalis with ozone gas and passive ultrasound activation","volume":"38","author":"Case","year":"2012","journal-title":"J. Endod."},{"issue":"4","key":"10.1016\/j.micpath.2026.108869_bib28","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00341-23","article-title":"Synergistic antibacterial effect of phage pB3074 in combination with antibiotics targeting cell wall against multidrug-resistant Acinetobacter baumannii in vitro and ex vivo","volume":"11","author":"Luo","year":"2023","journal-title":"Microbiol. Spectr."},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib29","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/s41522-021-00214-7","article-title":"Biofilm viability checker: an open-source tool for automated biofilm viability analysis from confocal microscopy images","volume":"7","author":"Mountcastle","year":"2021","journal-title":"NPJ Biofilms Microbiomes"},{"key":"10.1016\/j.micpath.2026.108869_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioflm.2022.100085","article-title":"Exposure of multidrug-resistant Klebsiella pneumoniae biofilms to 1,8-cineole leads to bacterial cell death and biomass disruption","volume":"4","author":"Vazquez","year":"2022","journal-title":"Biofilm"},{"issue":"9","key":"10.1016\/j.micpath.2026.108869_bib31","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/s41579-021-00559-y","article-title":"Prevotella diversity, niches and interactions with the human host","volume":"19","author":"Tett","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"issue":"9","key":"10.1016\/j.micpath.2026.108869_bib32","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/s41579-021-00559-y","article-title":"Prevotella diversity, niches and interactions with the human host","volume":"19","author":"Tett","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"issue":"12","key":"10.1016\/j.micpath.2026.108869_bib33","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1136\/gutjnl-2024-331880","article-title":"Puerarin alleviates atherosclerosis via the inhibition of Prevotella copri and its trimethylamine production","volume":"73","author":"Hao","year":"2024","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib49","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2340487","article-title":"Effects of Prevotella copri on insulin, gut microbiota and bile acids","volume":"16","author":"Gong","year":"2024","journal-title":"Gut Microbes"},{"issue":"2","key":"10.1016\/j.micpath.2026.108869_bib34","doi-asserted-by":"crossref","first-page":"e280","DOI":"10.1093\/infdis\/jiaf278","article-title":"Prevotella intermedia synergistically exacerbates pneumonia induced by oral Streptococci","volume":"232","author":"Ashizawa","year":"2025","journal-title":"J. Infect. Dis."},{"issue":"3","key":"10.1016\/j.micpath.2026.108869_bib35","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/s41579-024-01106-1","article-title":"Akkermansia muciniphila: biology, microbial ecology, host interactions and therapeutic potential","volume":"23","author":"Ioannou","year":"2025","journal-title":"Nat. Rev. Microbiol."},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib36","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40104-025-01319-1","article-title":"Metabolite-mediated crosstalk: unraveling the interactions between gut microbiota and host in fatty liver hemorrhagic syndrome of laying hens","volume":"17","author":"Zhang","year":"2026","journal-title":"J. Anim. Sci. Biotechnol."},{"issue":"12","key":"10.1016\/j.micpath.2026.108869_bib37","article-title":"Quercetin-driven Akkermansia muciniphila alleviates obesity by modulating bile acid metabolism via an ILA\/m6A\/CYP8B1 signaling","volume":"12","author":"Liu","year":"2025","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.micpath.2026.108869_bib38","doi-asserted-by":"crossref","DOI":"10.1038\/s41591-026-04394-7","article-title":"Pasteurized Akkermansia muciniphila MucT for weight loss maintenance in people with overweight and obesity: a controlled randomized trial","author":"Mount","year":"2026","journal-title":"Nat Med"},{"issue":"3","key":"10.1016\/j.micpath.2026.108869_bib39","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.cmet.2024.12.010","article-title":"Akkermansia muciniphila supplementation in patients with overweight\/obese type 2 diabetes: efficacy depends on its baseline levels in the gut","volume":"37","author":"Zhang","year":"2025","journal-title":"Cell Metab."},{"issue":"10","key":"10.1016\/j.micpath.2026.108869_bib40","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1111\/1751-7915.14293","article-title":"Akkermansia muciniphila alleviates high-fat-diet-related metabolic-associated fatty liver disease by modulating gut microbiota and bile acids","volume":"16","author":"Wu","year":"2023","journal-title":"Microb. Biotechnol."},{"issue":"2","key":"10.1016\/j.micpath.2026.108869_bib41","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.00816-20","article-title":"Calf diarrhea caused by prolonged expansion of autochthonous gut enterobacteriaceae and their lytic bacteriophages","volume":"6","author":"Whon","year":"2021","journal-title":"mSystems"},{"issue":"8","key":"10.1016\/j.micpath.2026.108869_bib42","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.2337\/db16-0278","article-title":"Connections between the gut microbiome and metabolic hormones in early pregnancy in overweight and obese women","volume":"65","author":"Gomez-Arango","year":"2016","journal-title":"Diabetes"},{"issue":"1","key":"10.1016\/j.micpath.2026.108869_bib43","doi-asserted-by":"crossref","first-page":"5813","DOI":"10.1038\/s41467-019-13721-1","article-title":"Relationship between gut microbiota and circulating metabolites in population-based cohorts","volume":"10","author":"Vojinovic","year":"2019","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.micpath.2026.108869_bib44","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1038\/s41591-025-03678-8","article-title":"Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis","volume":"31","author":"Chan","year":"2025","journal-title":"Nat Med"},{"issue":"8066","key":"10.1016\/j.micpath.2026.108869_bib45","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/s41586-025-08795-5","article-title":"Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3","volume":"642","author":"Chen","year":"2025","journal-title":"Nature"},{"issue":"11","key":"10.1016\/j.micpath.2026.108869_bib46","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1038\/s41590-025-02295-4","article-title":"Temporal and context-dependent requirements for the transcription factor Foxp3 expression in regulatory T cells","volume":"26","author":"Hu","year":"2025","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.micpath.2026.108869_bib47","doi-asserted-by":"crossref","first-page":"386","DOI":"10.3389\/fendo.2020.00386","article-title":"Modulation of the inflammatory response and bone healing","volume":"11","author":"Maruyama","year":"2020","journal-title":"Front. Endocrinol."}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026005954?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401026005954?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:36:12Z","timestamp":1791833772000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401026005954"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":51,"alternative-id":["S0882401026005954"],"URL":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108869","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phage-antibiotic synergy dismantles multidrug-resistant Enterococcus faecalis infection in SD rat apical periodontitis model","name":"articletitle","label":"Article Title"},{"value":"Microbial Pathogenesis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micpath.2026.108869","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108869"}}