{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:02:22Z","timestamp":1790614942917,"version":"4.1.0"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"vor","delay-in-days":366,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"UNF"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbiological Research"],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.1016\/j.micres.2015.06.012","type":"journal-article","created":{"date-parts":[[2015,7,18]],"date-time":"2015-07-18T00:20:53Z","timestamp":1437178853000},"page":"1-10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"special_numbering":"C","title":["Klebsiella pneumoniae O antigen loss alters the outer membrane protein composition and the selective packaging of proteins into secreted outer membrane vesicles"],"prefix":"10.1016","volume":"180","author":[{"given":"Bethaney K.","family":"Cahill","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent W.","family":"Seeley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dedra","family":"Gutel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terri N.","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.micres.2015.06.012_bib0005","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1128\/IAI.68.2.953-955.2000","article-title":"Capsular polysaccharide is a major complement resistance factor in lipopolysaccharide O side chain-deficient Klebsiella pneumoniae clinical isolates","volume":"68","author":"Alvarez","year":"2000","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.micres.2015.06.012_bib0010","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1128\/JB.182.1.248-251.2000","article-title":"Elongation factor Tu and DnaK are transferred from the cytoplasm to the periplasm of Escherichia coli during osmotic downshock presumably via the mechanosensitive channel mscL","volume":"182","author":"Berrier","year":"2000","journal-title":"J Bacteriol"},{"issue":"8","key":"10.1016\/j.micres.2015.06.012_bib0015","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1016\/j.bbamcr.2013.12.011","article-title":"Protein selection and export via outer membrane vesicles","volume":"1843","author":"Bonnington","year":"2014","journal-title":"Biochim Biophys Acta"},{"issue":"11","key":"10.1016\/j.micres.2015.06.012_bib0020","doi-asserted-by":"crossref","first-page":"9092","DOI":"10.1074\/jbc.M211177200","article-title":"Folding and insertion of the outer membrane protein OmpA is assisted by the chaperone Skp and by lipopolysaccharide","volume":"278","author":"Bulieris","year":"2003","journal-title":"J Biol Chem"},{"issue":"4","key":"10.1016\/j.micres.2015.06.012_bib0025","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1006\/mpat.1999.0339","article-title":"Recognition of B cells epitopes of the Klebsiella pneumoniae GroEL-like protein by HLA-B27 positive subjects","volume":"28","author":"Cancino-Diaz","year":"2000","journal-title":"Microb Pathog"},{"issue":"16","key":"10.1016\/j.micres.2015.06.012_bib0030","doi-asserted-by":"crossref","first-page":"3424","DOI":"10.1002\/pmic.201000212","article-title":"Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa","volume":"11","author":"Choi","year":"2011","journal-title":"Proteomics"},{"key":"10.1016\/j.micres.2015.06.012_bib0035","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/978-1-62703-245-2_16","article-title":"Quantitative and qualitative preparations of bacterial outer membrane vesicles","volume":"966","author":"Chutkan","year":"2013","journal-title":"Methods Mol Biol"},{"issue":"7","key":"10.1016\/j.micres.2015.06.012_bib0040","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1128\/JB.01999-12","article-title":"Identification of the mutation responsible for the temperature-sensitive lipopolysaccharide O-antigen defect in the Pseudomonas aeruginosa cystic fibrosis isolate 2192","volume":"195","author":"Davis","year":"2013","journal-title":"J Bacteriol"},{"issue":"8","key":"10.1016\/j.micres.2015.06.012_bib0045","doi-asserted-by":"crossref","first-page":"5114","DOI":"10.1074\/jbc.274.8.5114","article-title":"Non-lamellar structure and negative charges of lipopolysaccharides required for efficient folding of outer membrane protein PhoE of Escherichia coli","volume":"274","author":"de Cock","year":"1999","journal-title":"J Biol Chem"},{"issue":"6","key":"10.1016\/j.micres.2015.06.012_bib0050","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1111\/j.1365-2958.2009.06731.x","article-title":"Biogenesis of bacterial membrane vesicles","volume":"72","author":"Deatherage","year":"2009","journal-title":"Mol Microbiol"},{"issue":"2","key":"10.1016\/j.micres.2015.06.012_bib0055","doi-asserted-by":"crossref","first-page":"e00909","DOI":"10.1128\/mBio.00909-14","article-title":"Preferential packing of acidic glycosidases and proteases into Bacteroides outer membrane vesicles","volume":"5","author":"Elhenawy","year":"2014","journal-title":"mBio"},{"issue":"1","key":"10.1016\/j.micres.2015.06.012_bib0060","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1128\/MMBR.00031-09","article-title":"Virulence and immunomodulatory roles of bacterial outer membrane vesicles","volume":"74","author":"Ellis","year":"2010","journal-title":"Microbiol Mol Biol Rev"},{"issue":"14\u201315","key":"10.1016\/j.micres.2015.06.012_bib0065","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/S1286-4579(01)01494-0","article-title":"Salmonella typhimurium outer membrane remodeling: role in resistance to host innate immunity","volume":"3","author":"Ernst","year":"2001","journal-title":"Microbes Infect"},{"issue":"8","key":"10.1016\/j.micres.2015.06.012_bib0070","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S1286-4579(02)01604-0","article-title":"Structure and function of lipopolysaccharides","volume":"4","author":"Erridge","year":"2002","journal-title":"Microbes Infect"},{"issue":"1","key":"10.1016\/j.micres.2015.06.012_bib0075","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1128\/IAI.00864-09","article-title":"Roles of capsule and lipopolysaccharide O antigen in interactions of human monocyte-derived dendritic cells and Klebsiella pneumoniae","volume":"78","author":"Evrard","year":"2010","journal-title":"Infect Immun"},{"issue":"6","key":"10.1016\/j.micres.2015.06.012_bib0080","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1002\/pmic.200500164","article-title":"Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles","volume":"6","author":"Ferrari","year":"2006","journal-title":"Proteomics"},{"issue":"Pt 6","key":"10.1016\/j.micres.2015.06.012_bib0085","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1099\/mic.0.28611-0","article-title":"The ionic interaction of Klebsiella pneumoniae K2 capsule and core lipopolysaccharide","volume":"152","author":"Fresno","year":"2006","journal-title":"Microbiology"},{"issue":"30","key":"10.1016\/j.micres.2015.06.012_bib0090","doi-asserted-by":"crossref","first-page":"27604","DOI":"10.1074\/jbc.M504987200","article-title":"The role of galacturonic acid in outer membrane stability in Klebsiella pneumoniae","volume":"280","author":"Frirdich","year":"2005","journal-title":"J Biol Chem"},{"issue":"10","key":"10.1016\/j.micres.2015.06.012_bib0095","doi-asserted-by":"crossref","first-page":"4602","DOI":"10.1128\/IAI.66.10.4602-4610.1998","article-title":"Surface-associated hsp60 chaperonin of Legionella pneumophila mediates invasion in a HeLa cell model","volume":"66","author":"Garduno","year":"1998","journal-title":"Infect Immun"},{"issue":"31","key":"10.1016\/j.micres.2015.06.012_bib0100","doi-asserted-by":"crossref","first-page":"12875","DOI":"10.1073\/pnas.1109379108","article-title":"Small RNAs endow a transcriptional activator with essential repressor functions for single-tier control of a global stress regulon","volume":"108","author":"Gogol","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"37","key":"10.1016\/j.micres.2015.06.012_bib0105","doi-asserted-by":"crossref","first-page":"34247","DOI":"10.1074\/jbc.M201950200","article-title":"Pore formation and function of phosphoporin PhoE of Escherichia coli are determined by the core sugar moiety of lipopolysaccharide","volume":"277","author":"Hagge","year":"2002","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.micres.2015.06.012_bib0110","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1128\/JCM.37.1.56-62.1999","article-title":"Klebsiella pneumoniae lipopolysaccharide O typing: revision of prototype strains and O-group distribution among clinical isolates from different sources and countries","volume":"37","author":"Hansen","year":"1999","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.micres.2015.06.012_bib0115","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1515\/hsz-2014-0183","article-title":"Prokaryotic membrane vesicles: new insights on biogenesis and biological roles","volume":"396","author":"Haurat","year":"2014","journal-title":"Biol Chem"},{"issue":"2","key":"10.1016\/j.micres.2015.06.012_bib0120","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1074\/jbc.M110.185744","article-title":"Selective sorting of cargo proteins into bacterial membrane vesicles","volume":"286","author":"Haurat","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1016\/j.micres.2015.06.012_bib0125","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1477-5956-8-21","article-title":"Localization of proteins in the cell wall of Mycobacterium avium subsp. paratuberculosis K10 by proteomic analysis","volume":"8","author":"He","year":"2010","journal-title":"Proteome Sci"},{"issue":"17","key":"10.1016\/j.micres.2015.06.012_bib0130","doi-asserted-by":"crossref","first-page":"12489","DOI":"10.1074\/jbc.275.17.12489","article-title":"Enterotoxigenic Escherichia coli secretes active heat-labile enterotoxin via outer membrane vesicles","volume":"275","author":"Horstman","year":"2000","journal-title":"J Biol Chem"},{"issue":"3","key":"10.1016\/j.micres.2015.06.012_bib0135","doi-asserted-by":"crossref","first-page":"e33155","DOI":"10.1371\/journal.pone.0033155","article-title":"Lipopolysaccharide O1 antigen contributes to the virulence in Klebsiella pneumoniae causing pyogenic liver abscess","volume":"7","author":"Hsieh","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.micres.2015.06.012_bib0140","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jprot.2013.12.014","article-title":"Comprehensive proteomic profiling of outer membrane vesicles from Campylobacter jejuni","volume":"98","author":"Jang","year":"2014","journal-title":"J Proteomics"},{"issue":"14","key":"10.1016\/j.micres.2015.06.012_bib0145","doi-asserted-by":"crossref","first-page":"3998","DOI":"10.1128\/jb.177.14.3998-4008.1995","article-title":"Virulence factors are released from Pseudomonas aeruginosa in association with membrane vesicles during normal growth and exposure to gentamicin: a novel mechanism of enzyme secretion","volume":"177","author":"Kadurugamuwa","year":"1995","journal-title":"J Bacteriol"},{"issue":"18","key":"10.1016\/j.micres.2015.06.012_bib0150","doi-asserted-by":"crossref","first-page":"5798","DOI":"10.1128\/jb.175.18.5798-5805.1993","article-title":"Surface action of gentamicin on Pseudomonas aeruginosa","volume":"175","author":"Kadurugamuwa","year":"1993","journal-title":"J Bacteriol"},{"issue":"10","key":"10.1016\/j.micres.2015.06.012_bib0155","doi-asserted-by":"crossref","first-page":"5197","DOI":"10.1021\/pr1004983","article-title":"Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles","volume":"9","author":"Kahnt","year":"2010","journal-title":"J Proteome Res"},{"issue":"20","key":"10.1016\/j.micres.2015.06.012_bib0160","doi-asserted-by":"crossref","first-page":"5383","DOI":"10.1021\/ac025747h","article-title":"Empirical statistical model to estimate the accuracy of peptide identifications made by MS\/MS and database search","volume":"74","author":"Keller","year":"2002","journal-title":"Anal Chem"},{"key":"10.1016\/j.micres.2015.06.012_bib0165","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1146\/annurev.micro.091208.073413","article-title":"Biological functions and biogenesis of secreted bacterial outer membrane vesicles","volume":"64","author":"Kulp","year":"2010","journal-title":"Annu Rev Microbiol"},{"issue":"2","key":"10.1016\/j.micres.2015.06.012_bib0170","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1574-6968.2009.01669.x","article-title":"Proteome analysis of outer membrane vesicles from a clinical Acinetobacter baumannii isolate","volume":"297","author":"Kwon","year":"2009","journal-title":"FEMS Microbiol Lett"},{"issue":"19","key":"10.1016\/j.micres.2015.06.012_bib0175","doi-asserted-by":"crossref","first-page":"4425","DOI":"10.1128\/JB.00625-13","article-title":"Comparative proteome analysis of spontaneous outer membrane vesicles and purified outer membranes of Neisseria meningitidis","volume":"195","author":"Lappann","year":"2013","journal-title":"J Bacteriol"},{"issue":"6","key":"10.1016\/j.micres.2015.06.012_bib0180","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1002\/mas.20175","article-title":"Proteomics in gram-negative bacterial outer membrane vesicles","volume":"27","author":"Lee","year":"2008","journal-title":"Mass Spectrom Rev"},{"issue":"17","key":"10.1016\/j.micres.2015.06.012_bib0185","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1002\/pmic.200700196","article-title":"Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli","volume":"7","author":"Lee","year":"2007","journal-title":"Proteomics"},{"issue":"1","key":"10.1016\/j.micres.2015.06.012_bib0190","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1574-6968.2012.02549.x","article-title":"Klebsiella pneumoniae secretes outer membrane vesicles that induce the innate immune response","volume":"331","author":"Lee","year":"2012","journal-title":"FEMS Microbiol Lett"},{"issue":"4","key":"10.1016\/j.micres.2015.06.012_bib0195","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1021\/pr5010423","article-title":"Global analysis of Salmonella alternative sigma factor E on protein translation","volume":"14","author":"Li","year":"2015","journal-title":"J Proteome Res"},{"issue":"12","key":"10.1016\/j.micres.2015.06.012_bib0200","doi-asserted-by":"crossref","first-page":"e1001735","DOI":"10.1371\/journal.pbio.1001735","article-title":"Heat shock transcription factor sigma32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli","volume":"11","author":"Lim","year":"2013","journal-title":"PLoS Biol"},{"issue":"4","key":"10.1016\/j.micres.2015.06.012_bib0205","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"issue":"2","key":"10.1016\/j.micres.2015.06.012_bib0210","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1365-2958.2006.05522.x","article-title":"Release of outer membrane vesicles by Gram-negative bacteria is a novel envelope stress response","volume":"63","author":"McBroom","year":"2007","journal-title":"Mol Microbiol"},{"issue":"3","key":"10.1016\/j.micres.2015.06.012_bib0215","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1128\/IAI.01362-12","article-title":"Lipopolysaccharide-deficient Acinetobacter baumannii shows altered signaling through host Toll-like receptors and increased susceptibility to the host antimicrobial peptide LL-37","volume":"81","author":"Moffatt","year":"2013","journal-title":"Infect Immun"},{"issue":"7","key":"10.1016\/j.micres.2015.06.012_bib0220","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1128\/JB.01463-13","article-title":"Influence of O polysaccharides on biofilm development and outer membrane vesicle biogenesis in Pseudomonas aeruginosa PAO1","volume":"196","author":"Murphy","year":"2014","journal-title":"J Bacteriol"},{"issue":"17","key":"10.1016\/j.micres.2015.06.012_bib0225","doi-asserted-by":"crossref","first-page":"4646","DOI":"10.1021\/ac0341261","article-title":"A statistical model for identifying proteins by tandem mass spectrometry","volume":"75","author":"Nesvizhskii","year":"2003","journal-title":"Anal Chem"},{"issue":"4","key":"10.1016\/j.micres.2015.06.012_bib0230","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1128\/MMBR.67.4.593-656.2003","article-title":"Molecular basis of bacterial outer membrane permeability revisited","volume":"67","author":"Nikaido","year":"2003","journal-title":"Microbiol Mol Biol Rev"},{"issue":"1","key":"10.1016\/j.micres.2015.06.012_bib0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/MMBR.49.1.1-32.1985","article-title":"Molecular basis of bacterial outer membrane permeability","volume":"49","author":"Nikaido","year":"1985","journal-title":"Microbiol Rev"},{"issue":"4","key":"10.1016\/j.micres.2015.06.012_bib0240","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S1473-3099(09)70054-4","article-title":"The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria","volume":"9","author":"Nordmann","year":"2009","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"10.1016\/j.micres.2015.06.012_bib0245","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1523-5378.2006.00400.x","article-title":"Interleukin-6 induction by Helicobacter pylori in human macrophages is dependent on phagocytosis","volume":"11","author":"Odenbreit","year":"2006","journal-title":"Helicobacter"},{"issue":"Pt 4","key":"10.1016\/j.micres.2015.06.012_bib0250","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1099\/jmm.0.05044-0","article-title":"Expression of heterologous O-antigen in Yersinia pestis KIM does not affect virulence by the intravenous route","volume":"52","author":"Oyston","year":"2003","journal-title":"J Med Microbiol"},{"issue":"3","key":"10.1016\/j.micres.2015.06.012_bib0255","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1021\/pr1009756","article-title":"Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine","volume":"10","author":"Pierson","year":"2010","journal-title":"J Proteome Res"},{"issue":"3","key":"10.1016\/j.micres.2015.06.012_bib0260","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1021\/pr1009756","article-title":"Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine","volume":"10","author":"Pierson","year":"2011","journal-title":"J Proteome Res"},{"issue":"4","key":"10.1016\/j.micres.2015.06.012_bib0265","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1128\/CMR.11.4.589","article-title":"Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors","volume":"11","author":"Podschun","year":"1998","journal-title":"Clin Microbiol Rev"},{"issue":"6","key":"10.1016\/j.micres.2015.06.012_bib0270","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1111\/j.1365-2958.2010.07303.x","article-title":"Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH","volume":"77","author":"Schertzer","year":"2010","journal-title":"Mol Microbiol"},{"issue":"18","key":"10.1016\/j.micres.2015.06.012_bib0275","doi-asserted-by":"crossref","first-page":"3031","DOI":"10.1021\/bi400164t","article-title":"Envelope control of outer membrane vesicle production in Gram-negative bacteria","volume":"52","author":"Schwechheimer","year":"2013","journal-title":"Biochemistry"},{"issue":"3","key":"10.1016\/j.micres.2015.06.012_bib0280","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1128\/IAI.72.3.1423-1430.2004","article-title":"The Klebsiella pneumoniae O antigen contributes to bacteremia and lethality during murine pneumonia","volume":"72","author":"Shankar-Sinha","year":"2004","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.micres.2015.06.012_bib0285","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/j.1365-2958.2008.06392.x","article-title":"A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles","volume":"70","author":"Song","year":"2008","journal-title":"Mol Microbiol"},{"issue":"1","key":"10.1016\/j.micres.2015.06.012_bib0290","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1128\/JB.136.1.280-285.1978","article-title":"Cell envelope and shape of Escherichia coli: multiple mutants missing the outer membrane lipoprotein and other major outer membrane proteins","volume":"136","author":"Sonntag","year":"1978","journal-title":"J Bacteriol"},{"issue":"3","key":"10.1016\/j.micres.2015.06.012_bib0295","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0092-8674(00)80743-6","article-title":"A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein","volume":"97","author":"Spiess","year":"1999","journal-title":"Cell"},{"issue":"24","key":"10.1016\/j.micres.2015.06.012_bib0300","doi-asserted-by":"crossref","first-page":"7509","DOI":"10.1128\/JB.00722-09","article-title":"Outer membrane machinery and alginate synthesis regulators control membrane vesicle production in Pseudomonas aeruginosa","volume":"191","author":"Tashiro","year":"2009","journal-title":"J Bacteriol"},{"issue":"5338","key":"10.1016\/j.micres.2015.06.012_bib0305","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1126\/science.278.5338.631","article-title":"A genomic perspective on protein families","volume":"278","author":"Tatusov","year":"1997","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.micres.2015.06.012_bib0310","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1021\/pr0601741","article-title":"Comprehensive proteomic analysis of Shigella flexneri 2a membrane proteins","volume":"5","author":"Wei","year":"2006","journal-title":"J Proteome Res"},{"issue":"3","key":"10.1016\/j.micres.2015.06.012_bib0315","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1128\/IAI.01424-06","article-title":"Proteomic analysis of outer membranes and vesicles from wild-type serogroup B Neisseria meningitidis and a lipopolysaccharide-deficient mutant","volume":"75","author":"Williams","year":"2007","journal-title":"Infect Immun"},{"issue":"5","key":"10.1016\/j.micres.2015.06.012_bib0320","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/nmeth.1322","article-title":"Universal sample preparation method for proteome analysis","volume":"6","author":"Wisniewski","year":"2009","journal-title":"Nat Methods"},{"issue":"13","key":"10.1016\/j.micres.2015.06.012_bib0325","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1093\/bioinformatics\/btq249","article-title":"PSORTb 3.0: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes","volume":"26","author":"Yu","year":"2010","journal-title":"Bioinformatics"},{"issue":"3","key":"10.1016\/j.micres.2015.06.012_bib0330","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.micinf.2012.10.001","article-title":"Surface-associated GroEL facilitates the adhesion of Escherichia coli to macrophages through lectin-like oxidized low-density lipoprotein receptor-1","volume":"15","author":"Zhu","year":"2013","journal-title":"Microbes Infect"},{"issue":"5","key":"10.1016\/j.micres.2015.06.012_bib0335","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1074\/mcp.M113.029538","article-title":"Quantitative proteomics of the Neisseria gonorrhoeae cell envelope and membrane vesicles for the discovery of potential therapeutic targets","volume":"13","author":"Zielke","year":"2014","journal-title":"Mol Cell Proteomics"}],"container-title":["Microbiological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944501315001202?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944501315001202?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,5]],"date-time":"2020-09-05T05:34:58Z","timestamp":1599284098000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944501315001202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":67,"alternative-id":["S0944501315001202"],"URL":"https:\/\/doi.org\/10.1016\/j.micres.2015.06.012","relation":{},"ISSN":["0944-5013"],"issn-type":[{"value":"0944-5013","type":"print"}],"subject":[],"published":{"date-parts":[[2015,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Klebsiella pneumoniae O antigen loss alters the outer membrane protein composition and the selective packaging of proteins into secreted outer membrane vesicles","name":"articletitle","label":"Article Title"},{"value":"Microbiological Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micres.2015.06.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}