{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T15:42:54Z","timestamp":1789054974039,"version":"build-2803163510"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31871899"],"award-info":[{"award-number":["31871899"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31930110"],"award-info":[{"award-number":["31930110"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbiological Research"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.micres.2023.127450","type":"journal-article","created":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T06:14:13Z","timestamp":1689142453000},"page":"127450","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Dynamic evolution and transmission of a blaNDM-1-bearing fusion plasmid in a clinical Escherichia coli"],"prefix":"10.1016","volume":"275","author":[{"given":"Yanyun","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengcheng","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9amus","family":"Fanning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruichao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.micres.2023.127450_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179651","article-title":"Molecular and microbiological report of a hospital outbreak of NDM-1-carrying Enterobacteriaceae in Mexico","volume":"12","author":"Bocanegra-Ibarias","year":"2017","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.micres.2023.127450_bib2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0104899","article-title":"Closely related NDM-1-encoding plasmids from Escherichia coli and Klebsiella pneumoniae in Taiwan","volume":"9","author":"Chen","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.micres.2023.127450_bib3","unstructured":"CLSI, 2018. Performance Standards for Antimicrobial Susceptibility Testing. 30th ed. CLSI supplement M100."},{"issue":"3","key":"10.1016\/j.micres.2023.127450_bib4","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1093\/cid\/ciaa049","article-title":"Multispecies outbreak of verona integron-encoded metallo-\u00df-lactamase-producing multidrug resistant bacteria driven by a promiscuous incompatibility group A\/C2 plasmid","volume":"72","author":"de Man","year":"2021","journal-title":"Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am."},{"key":"10.1016\/j.micres.2023.127450_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.plasmid.2021.102568","article-title":"Molecular characterization of two novel NDM-1-producing atypical enteroaggregative Escherichia coli isolates from patients","volume":"115","author":"Du","year":"2021","journal-title":"Plasmid"},{"key":"10.1016\/j.micres.2023.127450_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2019.102599","article-title":"The transferability and evolution of NDM-1 and KPC-2 co-producing Klebsiella pneumoniae from clinical settings","volume":"51","author":"Gao","year":"2020","journal-title":"EBioMedicine"},{"issue":"1","key":"10.1016\/j.micres.2023.127450_bib7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s40121-020-00395-2","article-title":"Continuous evolution: perspective on the epidemiology of carbapenemase resistance among enterobacterales and other gram-negative bacteria","volume":"10","author":"Hansen","year":"2021","journal-title":"Infect. Dis. Ther."},{"issue":"11","key":"10.1016\/j.micres.2023.127450_bib8","doi-asserted-by":"crossref","first-page":"3184","DOI":"10.1093\/jac\/dkz327","article-title":"Emergence of a hybrid plasmid derived from IncN1-F33:A-:B- and mcr-1-bearing plasmids mediated by IS26","volume":"74","author":"He","year":"2019","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.micres.2023.127450_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.891807","article-title":"Coexistence of blaNDM-1 and blaIMP-4 in One Novel Hybrid Plasmid Confers Transferable Carbapenem Resistance in an ST20-K28 Klebsiella pneumoniae","volume":"13","author":"Jia","year":"2022","journal-title":"Front Microbiol"},{"issue":"1","key":"10.1016\/j.micres.2023.127450_bib10","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s12866-017-1012-8","article-title":"Structure, genetics and worldwide spread of New Delhi Metallo-beta-lactamase (NDM): a threat to public health","volume":"17","author":"Khan","year":"2017","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.micres.2023.127450_bib11","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1128\/mSystems.00134-20","article-title":"Deciphering the structural diversity and classification of the mobile tigecycline resistance gene tet(X)-Bearing Plasmidome among Bacteria","volume":"5","author":"Li","year":"2020","journal-title":"mSystems"},{"issue":"1","key":"10.1016\/j.micres.2023.127450_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2019.09.021","article-title":"Characterisation of a cointegrate plasmid harbouring bla(NDM-1) in a clinical Salmonella Lomita strain","volume":"55","author":"Li","year":"2020","journal-title":"Int J. Antimicrob. Agents"},{"key":"10.1016\/j.micres.2023.127450_bib13","first-page":"11","article-title":"Occurrence and characterization of NDM-1-producing Shewanella spp. and Acinetobacter portensis Co-Harboring tet(X3) in a Chinese Dairy Farm","volume":"10","author":"Li","year":"2022","journal-title":"Antibiotics"},{"issue":"3","key":"10.1016\/j.micres.2023.127450_bib14","doi-asserted-by":"crossref","DOI":"10.1128\/Spectrum.01577-21","article-title":"Genetic characterization and passage instability of a hybrid plasmid Co-Harboring blaIMP-4 and blaNDM-1 reveal the contribution of insertion sequences during plasmid formation and evolution","volume":"9","author":"Li","year":"2021","journal-title":"Microbiol Spectr."},{"issue":"6","key":"10.1016\/j.micres.2023.127450_bib15","doi-asserted-by":"crossref","DOI":"10.1128\/aac.00206-22","article-title":"Coexistence of bla(OXA-58) and bla(NDM-1) on a Novel Plasmid of GR59 from an Acinetobacter towneri Isolate","volume":"66","author":"Li","year":"2022","journal-title":"Antimicrob. Agents Chemother."},{"issue":"1","key":"10.1016\/j.micres.2023.127450_bib16","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/s11684-017-0608-6","article-title":"Trends of foodborne diseases in China: lessons from laboratory-based surveillance since 2011","volume":"12","author":"Liu","year":"2018","journal-title":"Front. Med."},{"issue":"12","key":"10.1016\/j.micres.2023.127450_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms9122435","article-title":"Structural diversity, fitness cost, and stability of a BlaNDM-1-Bearing cointegrate plasmid in Klebsiella pneumoniae and Escherichia coli","volume":"9","author":"Liu","year":"2021","journal-title":"Microorganisms"},{"issue":"3","key":"10.1016\/j.micres.2023.127450_bib18","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1053\/j.semdp.2019.04.011","article-title":"Carbapenem-resistant enterobacteriaceae: an emerging bacterial threat","volume":"36","author":"Lutgring","year":"2019","journal-title":"Semin Diagn. Pathol."},{"issue":"5","key":"10.1016\/j.micres.2023.127450_bib19","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1093\/jac\/dkz569","article-title":"Expression of AraC\/XylS stress response regulators in two distinct carbapenem-resistant Enterobacter cloacae ST89 biotypes","volume":"75","author":"Majewski","year":"2020","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.micres.2023.127450_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.740348","article-title":"Concurrent resistance to carbapenem and colistin among enterobacteriaceae recovered from human and animal sources in nigeria is associated with multiple genetic mechanisms","volume":"12","author":"Ngbede","year":"2021","journal-title":"Front. Microbiol."},{"issue":"5","key":"10.1016\/j.micres.2023.127450_bib21","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.molmed.2012.03.003","article-title":"Carbapenem resistance in enterobacteriaceae: here is the storm","volume":"18","author":"Nordmann","year":"2012","journal-title":"Trends Mol. Med"},{"issue":"2","key":"10.1016\/j.micres.2023.127450_bib22","doi-asserted-by":"crossref","DOI":"10.1128\/Spectrum.00503-21","article-title":"IS1294 reorganizes plasmids in a multidrug-resistant Escherichia coli strain","volume":"9","author":"Pan","year":"2021","journal-title":"Microbiol Spectr."},{"issue":"1","key":"10.1016\/j.micres.2023.127450_bib23","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.diagmicrobio.2010.12.002","article-title":"Multiplex PCR for detection of acquired carbapenemase genes","volume":"70","author":"Poirel","year":"2011","journal-title":"Diagn. Microbiol Infect. Dis."},{"key":"10.1016\/j.micres.2023.127450_bib24","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.drup.2016.09.002","article-title":"The rapid spread of carbapenem-resistant Enterobacteriaceae","volume":"29","author":"Potter","year":"2016","journal-title":"Drug Resist Updat"},{"issue":"1","key":"10.1016\/j.micres.2023.127450_bib25","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13100-021-00239-x","article-title":"The IS6 family, a clinically important group of insertion sequences including IS26","volume":"12","author":"Varani","year":"2021","journal-title":"Mob. DNA"},{"issue":"2","key":"10.1016\/j.micres.2023.127450_bib26","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00115-18","article-title":"NDM Metallo-\u03b2-Lactamases and their bacterial producers in health care settings","volume":"32","author":"Wu","year":"2019","journal-title":"Clin. Microbiol Rev."},{"issue":"5","key":"10.1016\/j.micres.2023.127450_bib27","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1093\/jac\/dkx540","article-title":"Recombination of plasmids in a carbapenem-resistant NDM-5-producing clinical Escherichia coli isolate","volume":"73","author":"Xie","year":"2018","journal-title":"J. Antimicrob. Chemother."},{"issue":"5","key":"10.1016\/j.micres.2023.127450_bib28","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1128\/AAC.34.5.755","article-title":"Biochemical characterization of a beta-lactamase that hydrolyzes penems and carbapenems from two Serratia marcescens isolates","volume":"34","author":"Yang","year":"1990","journal-title":"Antimicrob. Agents Chemother."},{"issue":"5","key":"10.1016\/j.micres.2023.127450_bib29","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/mmi.13407","article-title":"Evolved plasmid-host interactions reduce plasmid interference cost","volume":"101","author":"Yano","year":"2016","journal-title":"Mol. Microbiol"},{"issue":"12","key":"10.1016\/j.micres.2023.127450_bib30","doi-asserted-by":"crossref","first-page":"5046","DOI":"10.1128\/AAC.00774-09","article-title":"Characterization of a new metallo-beta-lactamase gene, blaNDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India","volume":"53","author":"Yong","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.micres.2023.127450_bib31","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.3389\/fmicb.2019.01994","article-title":"Characterization of Five Escherichia coli Isolates Co-expressing ESBL and MCR-1 Resistance Mechanisms From Different Origins in China","volume":"10","author":"Zhang","year":"2019","journal-title":"Front Microbiol"},{"issue":"4","key":"10.1016\/j.micres.2023.127450_bib32","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.00646-21","article-title":"IS26 is responsible for the evolution and transmission of blaNDM-Harboring plasmids in Escherichia coli of poultry Origin in China","volume":"6","author":"Zhao","year":"2021","journal-title":"mSystems"},{"issue":"5","key":"10.1016\/j.micres.2023.127450_bib33","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1093\/jac\/dkaa010","article-title":"Characterization of a blaNDM-1-carrying IncHI5 plasmid from Enterobacter cloacae complex of food-producing animal origin","volume":"75","author":"Zhu","year":"2020","journal-title":"J. Antimicrob. Chemother."},{"issue":"6","key":"10.1016\/j.micres.2023.127450_bib34","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms8060843","article-title":"Whole genome sequencing analysis of porcine faecal commensal Escherichia coli carrying class 1 integrons from sows and their offspring","volume":"8","author":"Zingali","year":"2020","journal-title":"Microorganisms"}],"container-title":["Microbiological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944501323001520?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944501323001520?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T05:41:10Z","timestamp":1727761270000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944501323001520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":34,"alternative-id":["S0944501323001520"],"URL":"https:\/\/doi.org\/10.1016\/j.micres.2023.127450","relation":{},"ISSN":["0944-5013"],"issn-type":[{"value":"0944-5013","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dynamic evolution and transmission of a blaNDM-1-bearing fusion plasmid in a clinical Escherichia coli","name":"articletitle","label":"Article Title"},{"value":"Microbiological Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micres.2023.127450","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"127450"}}