{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T04:59:57Z","timestamp":1783400397286,"version":"3.54.6"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T00:00:00Z","timestamp":1757721600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81873195"],"award-info":[{"award-number":["81873195"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018617","name":"Liaoning Revitalization Talents Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018617","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012465","name":"Dalian Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012465","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbiological Research"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.micres.2025.128342","type":"journal-article","created":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T14:23:39Z","timestamp":1757859819000},"page":"128342","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Faecalibacterium prausnitzii suppresses ovarian cancer by inducing ferroptosis via phenylalanine metabolism activation"],"prefix":"10.1016","volume":"304","author":[{"given":"Kaiyue","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuexue","family":"Huo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangzhe","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingting","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lunyue","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhao","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yudi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingchen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HyokChol","family":"Choe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junnan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunmei","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenlong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulin","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochi","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.micres.2025.128342_bib1","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.3390\/jcm12062216","article-title":"The Firmicutes\/Bacteroidetes ratio as a risk factor of breast cancer","volume":"12","author":"An","year":"2023","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.micres.2025.128342_bib2","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/s41598-023-27555-x","article-title":"Diagnostic and prognostic potential of the microbiome in ovarian cancer treatment response","volume":"13","author":"Asangba","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micres.2025.128342_bib3","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.annonc.2021.02.015","article-title":"The systemic treatment of recurrent ovarian cancer revisited","volume":"32","author":"Baert","year":"2021","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.micres.2025.128342_bib4","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s40168-018-0470-z","article-title":"Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2\u2019s q2-feature-classifier plugin","volume":"6","author":"Bokulich","year":"2018","journal-title":"Microbiome"},{"key":"10.1016\/j.micres.2025.128342_bib5","doi-asserted-by":"crossref","DOI":"10.1002\/imt2.238","article-title":"1Sangerbox 2: enhanced functionalities and update for a comprehensive clinical bioinformatics data analysis platform","volume":"3","author":"Chen","year":"2024","journal-title":"iMeta"},{"key":"10.1016\/j.micres.2025.128342_bib6","doi-asserted-by":"crossref","first-page":"423","DOI":"10.7150\/thno.22377","article-title":"Methylation-associated silencing of mir-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK\/ERK pathways","volume":"8","author":"Chen","year":"2018","journal-title":"Theranostics"},{"key":"10.1016\/j.micres.2025.128342_bib7","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1080\/15548627.2020.1810918","article-title":"Ferroptosis: machinery and regulation","volume":"17","author":"Chen","year":"2020","journal-title":"Autophagy"},{"key":"10.1016\/j.micres.2025.128342_bib8","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41571-020-00462-0","article-title":"Broadening horizons: the role of ferroptosis in cancer","volume":"18","author":"Chen","year":"2021","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.micres.2025.128342_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.761981","article-title":"Interaction between commensal bacteria, immune response and the intestinal barrier in inflammatory bowel disease","volume":"12","author":"Chen","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.micres.2025.128342_bib10","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1136\/gutjnl-2020-321153","article-title":"The role of gut microbiota in cancer treatment: friend or foe?","volume":"69","author":"Cheng","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.micres.2025.128342_bib11","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/S1470-2045(17)30279-6","article-title":"Bevacizumab and paclitaxel\u2013carboplatin chemotherapy and secondary cytoreduction in recurrent, platinum-sensitive ovarian cancer (NRG Oncology\/Gynecologic Oncology Group study GOG-0213): a multicentre, open-label, randomised, phase 3 trial","volume":"18","author":"Coleman","year":"2017","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.micres.2025.128342_bib12","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD005343.pub4","article-title":"Chemotherapy versus surgery for initial treatment in advanced ovarian epithelial cancer","author":"Coleridge","year":"2019","journal-title":"Cochrane Database Syst. Rev. 2 CD005343"},{"key":"10.1016\/j.micres.2025.128342_bib13","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/j.ijbiomac.2020.10.259","article-title":"Scutellaria baicalensis georgi polysaccharide ameliorates DSS-induced ulcerative colitis by improving intestinal barrier function and modulating gut microbiota","volume":"166","author":"Cui","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.micres.2025.128342_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.105135","article-title":"Targeting gut barrier dysfunction with phytotherapies: effective strategy against chronic diseases","volume":"161","author":"Dey","year":"2020","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.micres.2025.128342_bib15","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.3390\/biomedicines10051128","article-title":"faecalibacterium prausnitzii ameliorates colorectal tumorigenesis and suppresses proliferation of HCT116 colorectal cancer cells","volume":"10","author":"Dikeocha","year":"2022","journal-title":"Biomedicines"},{"key":"10.1016\/j.micres.2025.128342_bib16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/aac2.12071","article-title":"The gut microbiome in aging and ovarian cancer","volume":"5","author":"Dominique","year":"2024","journal-title":"Aging Cancer"},{"key":"10.1016\/j.micres.2025.128342_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0019963","article-title":"Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer","volume":"6","author":"Fong","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.micres.2025.128342_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.critrevonc.2021.103542","article-title":"Gut microbiota and its influence on ovarian cancer carcinogenesis, anticancer therapy and surgical treatment: a literature review","volume":"168","author":"Giudice","year":"2021","journal-title":"Crit. Rev. Oncol. \/Hematol."},{"key":"10.1016\/j.micres.2025.128342_bib19","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1053\/j.gastro.2023.08.052","article-title":"Traditional Medicine pien tze huang suppresses colorectal tumorigenesis through restoring gut microbiota and metabolites","volume":"165","author":"Gou","year":"2023","journal-title":"Gastroenterology"},{"key":"10.1016\/j.micres.2025.128342_bib20","doi-asserted-by":"crossref","first-page":"6292","DOI":"10.1038\/s41598-018-24573-y","article-title":"The impact of storage buffer, DNA extraction method, and polymerase on microbial analysis","volume":"8","author":"Hallmaier-Wacker","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.micres.2025.128342_bib21","article-title":"Gut microbes in gynecologic cancers: causes or biomarkers and therapeutic potential","volume":"12","author":"Han","year":"2022","journal-title":"Front. Oncol."},{"key":"10.1016\/j.micres.2025.128342_bib22","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1097\/00006250-200112000-00035","article-title":"Symptoms of ovarian cancer","volume":"98","author":"Hawkins","year":"2001","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.micres.2025.128342_bib23","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2105747118","article-title":"cGAS restricts colon cancer development by protecting intestinal barrier integrity","volume":"118","author":"Hu","year":"2021","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.micres.2025.128342_bib24","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2023.2221093","article-title":"Gut microbiota dysbiosis promotes the development of epithelial ovarian cancer via regulating hedgehog signaling pathway","volume":"15","author":"Hu","year":"2023","journal-title":"Gut Microbes"},{"key":"10.1016\/j.micres.2025.128342_bib25","first-page":"248","article-title":"Effects of plant polysaccharides on intestinal flora and metabolism in patients investigated using in vitro fermentation model","volume":"44","author":"Jia","year":"2023","journal-title":"Food Sci."},{"key":"10.1016\/j.micres.2025.128342_bib26","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/s41388-021-02139-z","article-title":"Single-cell RNA-seq recognized the initiator of epithelial ovarian cancer recurrence","volume":"41","author":"Kan","year":"2022","journal-title":"Oncogene"},{"key":"10.1016\/j.micres.2025.128342_bib27","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"HISAT: a fast spliced aligner with low memory requirements","volume":"12","author":"Kim","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.micres.2025.128342_bib28","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1038\/s43018-023-00617-9","article-title":"Clinical and translational advances in ovarian cancer therapy","volume":"4","author":"Konstantinopoulos","year":"2023","journal-title":"Nat. Cancer"},{"key":"10.1016\/j.micres.2025.128342_bib29","doi-asserted-by":"crossref","first-page":"5823","DOI":"10.1007\/s00432-022-04544-7","article-title":"Bacterial metabolite butyrate in modulating sorafenib-targeted microRNAs to curtail its resistance in hepatocellular carcinoma","volume":"149","author":"Kumar","year":"2023","journal-title":"J. Cancer Res Clin. Oncol."},{"key":"10.1016\/j.micres.2025.128342_bib30","doi-asserted-by":"crossref","first-page":"m3773","DOI":"10.1136\/bmj.m3773","article-title":"Treatment of epithelial ovarian cancer","author":"Kuroki","year":"2020","journal-title":"BMJ 371"},{"key":"10.1016\/j.micres.2025.128342_bib31","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/s41568-022-00459-0","article-title":"Targeting ferroptosis as a vulnerability in cancer","volume":"22","author":"Lei","year":"2022","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.micres.2025.128342_bib32","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1186\/s40168-024-01928-4","article-title":"An iron-binding protein of entomopathogenic fungus suppresses the proliferation of host symbiotic bacteria","volume":"12","author":"Li","year":"2024","journal-title":"Microbiome"},{"key":"10.1016\/j.micres.2025.128342_bib33","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/j.ccell.2023.06.011","article-title":"Carnobacterium maltaromaticum boosts intestinal vitamin d production to suppress colorectal cancer in female mice","volume":"41","author":"Li","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.micres.2025.128342_bib34","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.3748\/wjg.v26.i18.2187","article-title":"Role of gut microbiota on intestinal barrier function in acute pancreatitis","volume":"26","author":"Li","year":"2020","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.micres.2025.128342_bib35","doi-asserted-by":"crossref","first-page":"635","DOI":"10.3390\/pathogens14070635","article-title":"Gut\u2013Vaginal microbiome crosstalk in ovarian cancer: implications for early diagnosis","volume":"14","author":"Lin","year":"2025","journal-title":"Pathogens"},{"key":"10.1016\/j.micres.2025.128342_bib36","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2025.1528058","article-title":"Gut microbiota-derived metabolite phenylacetylglutamine inhibits the progression of prostate cancer by suppressing the Wnt\/\u03b2-catenin signaling pathway","volume":"16","author":"Lv","year":"2025","journal-title":"Front. Pharm."},{"key":"10.1016\/j.micres.2025.128342_bib37","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s12866-020-01739-1","article-title":"Alter between gut bacteria and blood metabolites and the anti-tumor effects of faecalibacterium prausnitzii in breast cancer","volume":"20","author":"Ma","year":"2020","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.micres.2025.128342_bib38","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.aninu.2021.09.012","article-title":"The interaction among gut microbes, the intestinal barrier and short chain fatty acids","volume":"9","author":"Ma","year":"2022","journal-title":"Anim. Nutr."},{"key":"10.1016\/j.micres.2025.128342_bib39","first-page":"210","article-title":"Anti-tumor activity of combination of hedyotic diffusa and scutellaria barbata","volume":"28","author":"Mo","year":"2016","journal-title":"Nat. Prod. Res Dev."},{"key":"10.1016\/j.micres.2025.128342_bib40","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.cell.2020.02.016","article-title":"A cardiovascular Disease-Linked gut microbial metabolite acts via adrenergic receptors","volume":"180","author":"Nemet","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.micres.2025.128342_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118656","article-title":"Scutellaria barbata D.Don and scleromitrion diffusum (Willd.) R.J.Wang inhibits the progression of triple negative breast cancer though the activation inhibition of NF-\u03baB triggered by CAFs-derived IL6","volume":"335","author":"Pan","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.micres.2025.128342_bib42","doi-asserted-by":"crossref","first-page":"D590","DOI":"10.1093\/nar\/gks1219","article-title":"The SILVA ribosomal RNA gene database project: improved data processing and web-based tools","volume":"41","author":"Quast","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.micres.2025.128342_bib43","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.mayocp.2018.09.013","article-title":"Mechanisms of disease: inflammatory bowel diseases","volume":"94","author":"Ramos","year":"2019","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.micres.2025.128342_bib44","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1001\/jamaoncol.2023.0197","article-title":"Advances in ovarian cancer care and unmet treatment needs for patients with platinum resistance: a narrative review","volume":"9","author":"Richardson","year":"2023","journal-title":"JAMA Oncol."},{"key":"10.1016\/j.micres.2025.128342_bib45","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.jaci.2015.12.1204","article-title":"News beyond our pages","volume":"137","author":"Rothenberg","year":"2016","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.micres.2025.128342_bib46","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/s40168-024-01961-3","article-title":"f. prausnitzii potentially modulates the association between citrus intake and depression","volume":"12","author":"Samuthpongtorn","year":"2024","journal-title":"Microbiome"},{"key":"10.1016\/j.micres.2025.128342_bib47","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1186\/s12916-025-04230-8","article-title":"faecalibacterium prausnitzii promotes anti-PD-L1 efficacy in natural killer\/T-cell lymphoma by enhancing antitumor immunity","volume":"23","author":"Shi","year":"2025","journal-title":"BMC Med"},{"key":"10.1016\/j.micres.2025.128342_bib48","first-page":"1683","article-title":"27-The gut microbiome and female health","volume":"11","author":"Siddiqui","year":"2022","journal-title":"Biol. (Basel)"},{"key":"10.1016\/j.micres.2025.128342_bib49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41419-022-05257-y","article-title":"Olaparib synergizes with arsenic trioxide by promoting apoptosis and ferroptosis in platinum-resistant ovarian cancer","volume":"13","author":"Tang","year":"2022","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.micres.2025.128342_bib50","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1038\/nbt.1621","article-title":"Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation","volume":"28","author":"Trapnell","year":"2010","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.micres.2025.128342_bib51","doi-asserted-by":"crossref","first-page":"547","DOI":"10.3390\/microorganisms8040547","article-title":"Investigation of adiposity measures and operational taxonomic unit (OTU) data transformation procedures in stool samples from a German cohort study using machine learning algorithms","volume":"8","author":"Troll","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.micres.2025.128342_bib52","doi-asserted-by":"crossref","first-page":"949","DOI":"10.3390\/nu14050949","article-title":"The intestinal barrier dysfunction as driving factor of inflammaging","volume":"14","author":"Untersmayr","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.micres.2025.128342_bib53","doi-asserted-by":"crossref","first-page":"16","DOI":"10.31083\/j.rcm2501016","article-title":"Iron dysregulation in cardiovascular diseases","volume":"25","author":"Wang","year":"2024","journal-title":"Rev. Cardiovasc Med"},{"key":"10.1016\/j.micres.2025.128342_bib54","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.3748\/wjg.v30.i12.1655","article-title":"Gut microbiota and female health","volume":"30","author":"Wang","year":"2024","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.micres.2025.128342_bib55","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/s41420-024-02037-9","article-title":"74-Ferroptosis: a double-edged sword","volume":"10","author":"Wang","year":"2024","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.micres.2025.128342_bib56","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.joim.2024.10.001","article-title":"A herbal pair of scutellaria barbata D. Don and scleromitrion diffusum (Willd.) R.J. Wang induced ferroptosis in ovarian cancer A2780 cells via inducing heme catabolism and ferritinophagy","volume":"22","author":"Wang","year":"2024","journal-title":"J. Integr. Med."},{"key":"10.1016\/j.micres.2025.128342_bib57","article-title":"Accurate prediction of absolute prokaryotic abundance from DNA concentration","volume":"5","author":"Wirbel","year":"2025","journal-title":"Cell Rep. Methods"},{"key":"10.1016\/j.micres.2025.128342_bib58","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1038\/s41575-019-0209-8","article-title":"Gut microbiota in colorectal cancer: mechanisms of action and clinical applications","volume":"16","author":"Wong","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.micres.2025.128342_bib59","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00253-019-10174-w","article-title":"Scutellariae radix and coptidis rhizoma ameliorate glycolipid metabolism of type 2 diabetic rats by modulating gut microbiota and its metabolites","volume":"104","author":"Xiao","year":"2020","journal-title":"Appl. Microbiol Biotechnol."},{"key":"10.1016\/j.micres.2025.128342_bib60","doi-asserted-by":"crossref","first-page":"320","DOI":"10.3390\/foods12020320","article-title":"The interaction between flavonoids and intestinal microbes: a review","volume":"12","author":"Xiong","year":"2023","journal-title":"Foods"},{"key":"10.1016\/j.micres.2025.128342_bib61","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1039\/C7FO01677H","article-title":"The effect of fucoidan on intestinal flora and intestinal barrier function in rats with breast cancer","volume":"9","author":"Xue","year":"2018","journal-title":"Food Funct."},{"key":"10.1016\/j.micres.2025.128342_bib62","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1038\/s41591-019-0458-7","article-title":"Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer","volume":"25","author":"Yachida","year":"2019","journal-title":"Nat. Med"},{"key":"10.1016\/j.micres.2025.128342_bib63","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41392-020-00428-9","article-title":"Ferroptosis: mechanisms and links with diseases","volume":"6","author":"Yan","year":"2021","journal-title":"Sig Transduct. Target Ther."},{"key":"10.1016\/j.micres.2025.128342_bib64","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/s41523-021-00262-4","article-title":"Circulating amino acids and amino acid-related metabolites and risk of breast cancer among predominantly premenopausal women","volume":"7","author":"Zeleznik","year":"2021","journal-title":"NPJ Breast Cancer"},{"key":"10.1016\/j.micres.2025.128342_bib65","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.trecan.2021.01.010","article-title":"Gut microbiota in cancer immune response and immunotherapy","volume":"7","author":"Zhou","year":"2021","journal-title":"Trends Cancer"}],"container-title":["Microbiological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944501325003015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944501325003015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T21:07:13Z","timestamp":1773868033000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944501325003015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":65,"alternative-id":["S0944501325003015"],"URL":"https:\/\/doi.org\/10.1016\/j.micres.2025.128342","relation":{},"ISSN":["0944-5013"],"issn-type":[{"value":"0944-5013","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Faecalibacterium prausnitzii suppresses ovarian cancer by inducing ferroptosis via phenylalanine metabolism activation","name":"articletitle","label":"Article Title"},{"value":"Microbiological Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micres.2025.128342","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"128342"}}