{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T06:04:26Z","timestamp":1783922666792,"version":"3.55.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Microbiological Research"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.micres.2026.128611","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T15:50:14Z","timestamp":1783007414000},"page":"128611","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Pseudorabies virus hijacks JNK to reprogram m6A machinery for sustaining replication"],"prefix":"10.1016","volume":"311","author":[{"given":"Juan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyu","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haimin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyan","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiyong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.micres.2026.128611_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111503","article-title":"Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis","volume":"41","author":"Al Moussawi","year":"2022","journal-title":"Cell. Rep."},{"issue":"6","key":"10.1016\/j.micres.2026.128611_bib2","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.220057","article-title":"Cell cycle-dependent binding between Cyclin B1 and Cdk1 revealed by time-resolved fluorescence correlation spectroscopy","volume":"12","author":"Barbiero","year":"2022","journal-title":"Open. Biol."},{"issue":"3","key":"10.1016\/j.micres.2026.128611_bib3","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1128\/jvi.20.3.583-588.1976","article-title":"RNA synthesis in cells infected with herpes simple virus. XIII. Differences in the methylation patterns of viral RNA during the reproductive cycle","volume":"20","author":"Bartkoski","year":"1976","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.micres.2026.128611_bib4","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/j.1742-4658.2012.08716.x","article-title":"Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling","volume":"280","author":"Caunt","year":"2013","journal-title":"FEBS J."},{"key":"10.1016\/j.micres.2026.128611_bib5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jare.2024.06.019","article-title":"WTAP\/YTHDF1-mediated m(6)A modification amplifies IFN-gamma-induced immunosuppressive properties of human MSCs","volume":"71","author":"Chen","year":"2025","journal-title":"J. Adv. Res."},{"issue":"10","key":"10.1016\/j.micres.2026.128611_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2024.114756","article-title":"HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma","volume":"43","author":"Chen","year":"2024","journal-title":"Cell. Rep."},{"issue":"4","key":"10.1016\/j.micres.2026.128611_bib7","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1053\/j.gastro.2022.06.024","article-title":"METTL3 Inhibits Antitumor Immunity by Targeting m(6)A-BHLHE41-CXCL1\/CXCR2 Axis to Promote Colorectal Cancer","volume":"163","author":"Chen","year":"2022","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.micres.2026.128611_bib8","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s13567-024-01336-4","article-title":"TRIM26 facilitates PRV infection through NDP52-mediated autophagic degradation of MAVS","volume":"55","author":"Chengyue","year":"2024","journal-title":"Vet. Res."},{"issue":"6","key":"10.1016\/j.micres.2026.128611_bib9","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01811-21","article-title":"Hepatitis C Virus-Induced ROS\/JNK Signaling Pathway Activates the E3 Ubiquitin Ligase Itch to Promote the Release of HCV Particles via Polyubiquitylation of VPS4A","volume":"96","author":"Deng","year":"2022","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.micres.2026.128611_bib10","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.molcel.2019.11.007","article-title":"Altered m(6)A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection","volume":"77","author":"Gokhale","year":"2020","journal-title":"Mol. Cell."},{"issue":"7","key":"10.1016\/j.micres.2026.128611_bib11","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/ncb2071","article-title":"Interplay between Cdh1 and JNK activity during the cell cycle","volume":"12","author":"Gutierrez","year":"2010","journal-title":"Nat. Cell. Biol."},{"key":"10.1016\/j.micres.2026.128611_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.gde.2024.102213","article-title":"Recent insights into N(6)-methyladenosine during viral infection","volume":"87","author":"Horner","year":"2024","journal-title":"Curr. Opin. Genet. Dev."},{"issue":"35","key":"10.1016\/j.micres.2026.128611_bib13","doi-asserted-by":"crossref","first-page":"8829","DOI":"10.1073\/pnas.1808319115","article-title":"N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle","volume":"115","author":"Imam","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"8","key":"10.1016\/j.micres.2026.128611_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.107310","article-title":"Alphaherpesvirus-mediated remodeling of the cellular transcriptome results in depletion of m6A-containing transcripts","volume":"26","author":"Jansens","year":"2023","journal-title":"iScience"},{"issue":"3","key":"10.1016\/j.micres.2026.128611_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111107","article-title":"Alphaherpesvirus US3 protein-mediated inhibition of the m6A mRNA methyltransferase complex","volume":"40","author":"Jansens","year":"2022","journal-title":"Cell. Rep."},{"issue":"24","key":"10.1016\/j.micres.2026.128611_bib16","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2508475122","article-title":"N6-methyladenosine modification of HCMV IE1 transcript promotes the repressive state of viral genome to achieve latent infection","volume":"122","author":"Jeong","year":"2025","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"12","key":"10.1016\/j.micres.2026.128611_bib17","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/nchembio.687","article-title":"N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO","volume":"7","author":"Jia","year":"2011","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.micres.2026.128611_bib18","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.943707","article-title":"The Inactivated gE\/TK Gene-Deleted Vaccine Against Pseudorabies Virus Type II Confers Effective Protection in Mice and Pigs","volume":"13","author":"Jin","year":"2022","journal-title":"Front. Microbiol."},{"issue":"2","key":"10.1016\/j.micres.2026.128611_bib19","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s10555-008-9123-1","article-title":"Dual-specificity MAP kinase phosphatases (MKPs) and cancer","volume":"27","author":"Keyse","year":"2008","journal-title":"Cancer Metastas-.-. Rev."},{"issue":"6","key":"10.1016\/j.micres.2026.128611_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007796","article-title":"EBV epitranscriptome reprogramming by METTL14 is critical for viral-associated tumorigenesis","volume":"15","author":"Lang","year":"2019","journal-title":"PLoS. Pathog."},{"issue":"2","key":"10.1016\/j.micres.2026.128611_bib21","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s12275-019-9021-y","article-title":"Determination of protein phosphorylation by polyacrylamide gel electrophoresis","volume":"57","author":"Lee","year":"2019","journal-title":"J. Microbiol."},{"issue":"1","key":"10.1016\/j.micres.2026.128611_bib22","doi-asserted-by":"crossref","first-page":"4549","DOI":"10.1038\/s41467-022-32163-w","article-title":"Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH)","volume":"13","author":"Li","year":"2022","journal-title":"Nat. Commun."},{"issue":"12","key":"10.1016\/j.micres.2026.128611_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1012712","article-title":"A previously unidentified circRNA inhibits virus replication by regulating the miR-24-3p\/KEAP1 axis","volume":"20","author":"Li","year":"2024","journal-title":"PLoS. Pathog."},{"issue":"6","key":"10.1016\/j.micres.2026.128611_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109091","article-title":"METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection","volume":"35","author":"Li","year":"2021","journal-title":"Cell. Rep."},{"issue":"12","key":"10.1016\/j.micres.2026.128611_bib25","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/s41419-019-2128-6","article-title":"eIF2alpha-CHOP-BCl-2\/JNK and IRE1alpha-XBP1\/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus","volume":"10","author":"Li","year":"2019","journal-title":"Cell. Death Dis."},{"issue":"7667","key":"10.1016\/j.micres.2026.128611_bib26","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/nature23450","article-title":"m(6)A mRNA methylation controls T cell homeostasis by targeting the IL-7\/STAT5\/SOCS pathways","volume":"548","author":"Li","year":"2017","journal-title":"Nature"},{"issue":"15","key":"10.1016\/j.micres.2026.128611_bib27","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202400545R","article-title":"Targeted inhibition of m6A demethylase FTO by FB23 attenuates allergic inflammation in the airway epithelium","volume":"38","author":"Lian","year":"2024","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.micres.2026.128611_bib28","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2025.2572761","article-title":"Influenza NS1 drives N(6)-methyladenosine (m(6)A)-mediated autoregulation of viral mRNA splicing","volume":"14","author":"Liao","year":"2025","journal-title":"Emerg. Microbes Infect."},{"issue":"23","key":"10.1016\/j.micres.2026.128611_bib29","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01522-22","article-title":"Porcine Circovirus Type 2 Hijacks Host IPO5 to Sustain the Intracytoplasmic Stability of Its Capsid Protein","volume":"96","author":"Lin","year":"2022","journal-title":"J. Virol."},{"issue":"11","key":"10.1016\/j.micres.2026.128611_bib30","doi-asserted-by":"crossref","first-page":"e3690","DOI":"10.1093\/cid\/ciaa987","article-title":"A Novel Human Acute Encephalitis Caused by Pseudorabies Virus Variant Strain","volume":"73","author":"Liu","year":"2021","journal-title":"Clin. Infect. Dis."},{"issue":"7","key":"10.1016\/j.micres.2026.128611_bib31","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1080\/15548627.2024.2330105","article-title":"Foot-and-mouth disease virus VP1 degrades YTHDF2 through autophagy to regulate IRF3 activity for viral replication","volume":"20","author":"Liu","year":"2024","journal-title":"Autophagy"},{"issue":"2","key":"10.1016\/j.micres.2026.128611_bib32","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/nchembio.1432","article-title":"A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation","volume":"10","author":"Liu","year":"2014","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.micres.2026.128611_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.109706","article-title":"Lidocaine inhibits influenza a virus replication by up-regulating IFNalpha4 via TBK1-IRF7 and JNK-AP1 signaling pathways","volume":"115","author":"Liu","year":"2023","journal-title":"Int. Immunopharmacol."},{"issue":"4","key":"10.1016\/j.micres.2026.128611_bib34","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/s41419-021-03585-z","article-title":"Emerging role of RNA modification N6-methyladenosine in immune evasion","volume":"12","author":"Lou","year":"2021","journal-title":"Cell. Death Dis."},{"issue":"4","key":"10.1016\/j.micres.2026.128611_bib35","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/s41564-019-0653-9","article-title":"N(6)-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I","volume":"5","author":"Lu","year":"2020","journal-title":"Nat. Microbiol."},{"issue":"5","key":"10.1016\/j.micres.2026.128611_bib36","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.tibs.2020.11.008","article-title":"N(6)-Methyladenosine Regulates Host Responses to Viral Infection","volume":"46","author":"McFadden","year":"2021","journal-title":"Trends Biochem. Sci."},{"issue":"8","key":"10.1016\/j.micres.2026.128611_bib37","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1080\/15548627.2021.2002101","article-title":"Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy","volume":"18","author":"Ming","year":"2022","journal-title":"Autophagy"},{"issue":"8","key":"10.1016\/j.micres.2026.128611_bib38","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/s41419-021-04028-5","article-title":"C5aR1-positive neutrophils promote breast cancer glycolysis through WTAP-dependent m6A methylation of ENO1","volume":"12","author":"Ou","year":"2021","journal-title":"Cell. Death Dis."},{"key":"10.1016\/j.micres.2026.128611_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.174884","article-title":"HM-chromanone attenuates TNF-alpha-mediated inflammation and insulin resistance by controlling JNK activation and NF-kappaB pathway in 3T3-L1 adipocytes","volume":"921","author":"Park","year":"2022","journal-title":"Eur. J. Pharmacol."},{"issue":"7620","key":"10.1016\/j.micres.2026.128611_bib40","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/nature19342","article-title":"m(6)A RNA methylation promotes XIST-mediated transcriptional repression","volume":"537","author":"Patil","year":"2016","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.micres.2026.128611_bib41","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/cr.2014.3","article-title":"Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase","volume":"24","author":"Ping","year":"2014","journal-title":"Cell. Res."},{"issue":"6","key":"10.1016\/j.micres.2026.128611_bib42","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/s41419-024-06831-2","article-title":"ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability","volume":"15","author":"Reddi","year":"2024","journal-title":"Cell. Death Dis."},{"issue":"10","key":"10.1016\/j.micres.2026.128611_bib43","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1038\/s41423-022-00913-x","article-title":"Extracellular sulfatase-2 is overexpressed in rheumatoid arthritis and mediates the TNF-alpha-induced inflammatory activation of synovial fibroblasts","volume":"19","author":"Siegel","year":"2022","journal-title":"Cell. Mol. Immunol."},{"issue":"3","key":"10.1016\/j.micres.2026.128611_bib44","doi-asserted-by":"crossref","DOI":"10.1093\/jmcb\/mjac011","article-title":"Versatile functions of RNA m6A machinery on chromatin","volume":"14","author":"Song","year":"2022","journal-title":"J. Mol. Cell. Biol."},{"issue":"30","key":"10.1016\/j.micres.2026.128611_bib45","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2104805118","article-title":"Widespread remodeling of the m(6)A RNA-modification landscape by a viral regulator of RNA processing and export","volume":"118","author":"Srinivas","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"4","key":"10.1016\/j.micres.2026.128611_bib46","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.molcel.2020.10.026","article-title":"Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m(6)A Methylation","volume":"80","author":"Sun","year":"2020","journal-title":"Mol. Cell."},{"issue":"9","key":"10.1016\/j.micres.2026.128611_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.113123","article-title":"JNK mediates cell death by promoting the ubiquitination of the apurinic\/apyrimidinic endonuclease APE1","volume":"42","author":"Tabanifar","year":"2023","journal-title":"Cell. Rep."},{"key":"10.1016\/j.micres.2026.128611_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.115307","article-title":"JNK in inflammation and lipid metabolism regulation in atherosclerosis","volume":"164","author":"Tang","year":"2025","journal-title":"Int. Immunopharmacol."},{"issue":"5467","key":"10.1016\/j.micres.2026.128611_bib49","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1126\/science.288.5467.870","article-title":"Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway","volume":"288","author":"Tournier","year":"2000","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.micres.2026.128611_bib50","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01723-24","article-title":"The role of N(6)-methyladenosine (m(6)A) mRNA modifications in herpesvirus infections","volume":"99","author":"Verhamme","year":"2025","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.micres.2026.128611_bib51","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.02019-24","article-title":"The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression","volume":"99","author":"Verhamme","year":"2025","journal-title":"J. Virol."},{"issue":"1","key":"10.1016\/j.micres.2026.128611_bib52","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1080\/21505594.2022.2127192","article-title":"Porcine epidemic diarrhoea virus (PEDV) infection activates AMPK and JNK through TAK1 to induce autophagy and enhance virus replication","volume":"13","author":"Wang","year":"2022","journal-title":"Virulence"},{"key":"10.1016\/j.micres.2026.128611_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.lanmic.2026.101351","article-title":"Spillover of pseudorabies virus variants to humans: an urgent call for pseudorabies eradication in domestic pigs","author":"Wang","year":"2026","journal-title":"Lancet Microbe"},{"issue":"23","key":"10.1016\/j.micres.2026.128611_bib54","doi-asserted-by":"crossref","DOI":"10.3390\/ijms252313140","article-title":"Evasion of the Antiviral Innate Immunity by PRV","volume":"25","author":"Wang","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"7481","key":"10.1016\/j.micres.2026.128611_bib55","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nature12730","article-title":"N6-methyladenosine-dependent regulation of messenger RNA stability","volume":"505","author":"Wang","year":"2014","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.micres.2026.128611_bib56","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1013234","article-title":"ERK-METTL3 axis acts as a novel regulator of antiviral innate immunity combating pseudorabies virus infection","volume":"21","author":"Wang","year":"2025","journal-title":"PLoS. Pathog."},{"issue":"6454","key":"10.1016\/j.micres.2026.128611_bib57","doi-asserted-by":"crossref","DOI":"10.1126\/science.aav0758","article-title":"Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses","volume":"365","author":"Wang","year":"2019","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.micres.2026.128611_bib58","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.cell.2015.05.014","article-title":"N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency","volume":"161","author":"Wang","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.micres.2026.128611_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2024.110335","article-title":"MDV-encoded protein kinase U(S)3 phosphorylates WTAP to inhibit transcriptomic m(6)A modification and cellular protein translation","volume":"300","author":"Wang","year":"2025","journal-title":"Vet. Microbiol."},{"issue":"3","key":"10.1016\/j.micres.2026.128611_bib60","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1016\/S0021-9258(17)43484-3","article-title":"Phosphorylation-induced mobility shift in phospholamban in sodium dodecyl sulfate-polyacrylamide gels. Evidence for a protein structure consisting of multiple identical phosphorylatable subunits","volume":"259","author":"Wegener","year":"1984","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.micres.2026.128611_bib61","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01545-22","article-title":"Pseudorabies Virus Regulates the Extracellular Translocation of Annexin A2 To Promote Its Proliferation","volume":"97","author":"Weng","year":"2023","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.micres.2026.128611_bib62","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.molcel.2016.01.012","article-title":"Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing","volume":"61","author":"Xiao","year":"2016","journal-title":"Mol. Cell."},{"issue":"1","key":"10.1016\/j.micres.2026.128611_bib63","doi-asserted-by":"crossref","first-page":"4595","DOI":"10.1038\/s41467-019-12504-y","article-title":"Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus","volume":"10","author":"Xue","year":"2019","journal-title":"Nat. Commun."},{"issue":"16","key":"10.1016\/j.micres.2026.128611_bib64","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00466-17","article-title":"Kaposi's Sarcoma-Associated Herpesvirus Utilizes and Manipulates RNA N(6)-Adenosine Methylation To Promote Lytic Replication","volume":"91","author":"Ye","year":"2017","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.micres.2026.128611_bib65","doi-asserted-by":"crossref","DOI":"10.3390\/v14030547","article-title":"A Tug of War: Pseudorabies Virus and Host Antiviral Innate Immunity","volume":"14","author":"Ye","year":"2022","journal-title":"Viruses"},{"key":"10.1016\/j.micres.2026.128611_bib66","article-title":"Pseudorabies virus exploits N(6)-methyladenosine modification to promote viral replication","volume":"14","author":"Yu","year":"2023","journal-title":"Front. Microbiol."},{"issue":"10","key":"10.1016\/j.micres.2026.128611_bib67","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/s41580-023-00654-3","article-title":"Publisher Correction: Reading, writing and erasing mRNA methylation","volume":"24","author":"Zaccara","year":"2023","journal-title":"Nat. Rev. Mol. Cell. Biol."},{"issue":"9","key":"10.1016\/j.micres.2026.128611_bib68","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/s41588-020-0644-z","article-title":"Genetic analyses support the contribution of mRNA N(6)-methyladenosine (m(6)A) modification to human disease heritability","volume":"52","author":"Zhang","year":"2020","journal-title":"Nat. Genet."},{"issue":"3","key":"10.1016\/j.micres.2026.128611_bib69","doi-asserted-by":"crossref","DOI":"10.1002\/jmv.28591","article-title":"Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins","volume":"95","author":"Zhang","year":"2023","journal-title":"J. Med. Virol."},{"issue":"1","key":"10.1016\/j.micres.2026.128611_bib70","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1186\/s13059-019-1915-9","article-title":"RADAR: differential analysis of MeRIP-seq data with a random effect model","volume":"20","author":"Zhang","year":"2019","journal-title":"Genome Biol."},{"key":"10.1016\/j.micres.2026.128611_bib71","article-title":"Identification and Characterization of BmNPV m6A Sites and Their Possible Roles During Viral Infection","volume":"13","author":"Zhang","year":"2022","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.micres.2026.128611_bib72","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.molcel.2012.10.015","article-title":"ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility","volume":"49","author":"Zheng","year":"2013","journal-title":"Mol. Cell."},{"issue":"4","key":"10.1016\/j.micres.2026.128611_bib73","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1012146","article-title":"Pseudorabies virus gM and its homologous proteins in herpesviruses induce mitochondria-related apoptosis involved in viral pathogenicity","volume":"20","author":"Zhou","year":"2024","journal-title":"PLoS. Pathog."},{"issue":"4","key":"10.1016\/j.micres.2026.128611_bib74","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011305","article-title":"N6-methyladenosine reader protein YTHDC1 regulates influenza A virus NS segment splicing and replication","volume":"19","author":"Zhu","year":"2023","journal-title":"PLoS. Pathog."},{"issue":"1","key":"10.1016\/j.micres.2026.128611_bib75","doi-asserted-by":"crossref","first-page":"5595","DOI":"10.1038\/s41467-024-49969-5","article-title":"Author Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice","volume":"15","author":"Zhuang","year":"2024","journal-title":"Nat. Commun."}],"container-title":["Microbiological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944501326001758?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0944501326001758?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T05:05:34Z","timestamp":1783919134000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0944501326001758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":75,"alternative-id":["S0944501326001758"],"URL":"https:\/\/doi.org\/10.1016\/j.micres.2026.128611","relation":{},"ISSN":["0944-5013"],"issn-type":[{"value":"0944-5013","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pseudorabies virus hijacks JNK to reprogram m6A machinery for sustaining replication","name":"articletitle","label":"Article Title"},{"value":"Microbiological Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micres.2026.128611","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier GmbH. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"128611"}}