{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T04:26:56Z","timestamp":1781324816563,"version":"3.54.1"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003758","name":"Foundation for Research Support and Scientific and Technological Development of Maranh\u00e3o","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003758","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordination for the improvement of Higher Education Personnel","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Micron"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.micron.2025.103940","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T13:46:23Z","timestamp":1760535983000},"page":"103940","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Thymol enhances the acaricidal effects of cypermethrin through the disruption of oocyte development in Rhipicephalus microplus (Acari: Ixodidae)"],"prefix":"10.1016","volume":"200","author":[{"given":"Matheus","family":"Nobate-Gomes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia Rosa","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella Chaves","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dauana","family":"Mesquita-Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00e1ssia Lopes","family":"do Vale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga Oliveira","family":"dos Anjos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caio Marcio Oliveira","family":"Monteiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livio Martins Costa","family":"Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9546-7599","authenticated-orcid":false,"given":"Caio Pav\u00e3o","family":"Tavares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.micron.2025.103940_bib1","first-page":"719","article-title":"Adulticidal, larvicidal, and repellent potential of ethyl acetate extract of moringa oleifera against rhipicephalus microplus cattle ticks","volume":"30","author":"Abbas","year":"2024","journal-title":"Kafkas Univ. Vet. Fak. Derg."},{"issue":"1-2","key":"10.1016\/j.micron.2025.103940_bib2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.vetpar.2014.03.006","article-title":"Acaricide resistance in cattle ticks and approaches to its management: the state of play","volume":"203","author":"Abbas","year":"2014","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.micron.2025.103940_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2021.104776","article-title":"A retrospective review on ixodid tick resistance against synthetic acaricides: implications and perspectives for future resistance prevention and mitigation","volume":"173","author":"Agwunobi","year":"2021","journal-title":"Pestic. Biochem. Physiol."},{"issue":"1","key":"10.1016\/j.micron.2025.103940_bib4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s10096-010-1050-8","article-title":"Fungicidal activity of thymol and carvacrol by disrupting ergosterol biosynthesis and membrane integrity against candida","volume":"30","author":"Ahmad","year":"2011","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"issue":"2","key":"10.1016\/j.micron.2025.103940_bib5","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s10493-020-00506-1","article-title":"Toxicity, repellency and anti-cholinesterase activities of thymol-eucalyptus combinations against phenotypically resistant rhipicephalus annulatus ticks","volume":"81","author":"Arafa","year":"2020","journal-title":"Exp. Appl. Acarol."},{"key":"10.1016\/j.micron.2025.103940_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2021.109346","article-title":"Control of rhipicephalus annulatus resistant to deltamethrin by spraying infested cattle with synergistic eucalyptus essential oil-thymol-deltamethrin combination","volume":"290","author":"Arafa","year":"2021","journal-title":"Vet. Parasitol."},{"issue":"4","key":"10.1016\/j.micron.2025.103940_bib7","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/mve.12181","article-title":"Synergism of thymol, carvacrol and eugenol in larvae of the cattle tick, rhipicephalus microplus, and brown dog tick, rhipicephalus sanguineus","volume":"30","author":"Ara\u00fajo","year":"2016","journal-title":"Med. Vet. Entomol."},{"issue":"2","key":"10.1016\/j.micron.2025.103940_bib8","first-page":"575580","article-title":"Effects of ricinoleic acid esters from castor oil of ricinus communis on the vitellogenesis of rhipicephalus sanguineus (Latreille, 1806)(Acari: Ixodidae) ticks","volume":"127","author":"Arnosti","year":"2011","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.micron.2025.103940_bib9","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jddst.2015.10.007","article-title":"Effect of chemical penetration enhancer on transdermal iontophoretic delivery of diclofenac sodium under constant voltage","volume":"30","author":"Arunkumar","year":"2015","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"10.1016\/j.micron.2025.103940_bib10","series-title":"Inside ticks: morphophysiology, toxicology and therapeutic perspectives","article-title":"S\u00e3o paulo","author":"Camargo-Mathias","year":"2018"},{"issue":"2","key":"10.1016\/j.micron.2025.103940_bib11","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s10493-017-0144-8","article-title":"Deltamethrin as inductor agent of precocious ovarian degeneration in rhipicephalus sanguineus sl (Acari: Ixodidae) ticks","volume":"72","author":"Camargo-Mathias","year":"2017","journal-title":"Exp. Appl. Acarol."},{"issue":"9","key":"10.1016\/j.micron.2025.103940_bib12","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1080\/03639040601150294","article-title":"The effect of mixed-solvent and terpenes on percutaneous absorption of meloxicam gel","volume":"33","author":"Chang","year":"2007","journal-title":"Drug Dev. Ind. Pharm."},{"key":"10.1016\/j.micron.2025.103940_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2019.108989","article-title":"Combination of thymol and eugenol for the control of rhipicephalus sanguineus sensu lato: evaluation of synergism on immature stages and formulation development","volume":"277","author":"Coelho","year":"2020","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.micron.2025.103940_bib14","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.vetpar.2016.05.028","article-title":"Acaricidal efficacies of lippia gracilis essential oil and its phytochemicals against organophosphate-resistant and susceptible strains of rhipicephalus (Boophilus) microplus","volume":"228","author":"Costa-J\u00fanior","year":"2016","journal-title":"Vet. Parasitol."},{"issue":"3","key":"10.1016\/j.micron.2025.103940_bib15","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/mve.12444","article-title":"1, 8-cineole and castor oil in sodium lauryl ether sulphate disrupt reproduction and ovarian tissue of rhipicephalus (Boophilus) microplus","volume":"34","author":"De Queiroz","year":"2020","journal-title":"Med. Vet. Entomol."},{"issue":"1","key":"10.1016\/j.micron.2025.103940_bib16","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1093\/jee\/66.1.130","article-title":"Boophilus annulatus and B. Microplus: laboratory tests of insecticides","volume":"66","author":"Drummond","year":"1973","journal-title":"J. Econ. Entomol."},{"issue":"159","key":"10.1016\/j.micron.2025.103940_bib17","first-page":"26","article-title":"O carrapato dos bovinos e a resist\u00eancia: temos o que comemorar","volume":"27","author":"Furlong","year":"2007","journal-title":"A hora Veter.. \u00e1ria"},{"key":"10.1016\/j.micron.2025.103940_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2023.110112","article-title":"Efficacy and safety of geranium-oregano-thymol formulations to control dog tick rhipicephalus sanguineus sensu lato under laboratory and field conditions","volume":"327","author":"Gadelhaq","year":"2024","journal-title":"Vet. Parasitol."},{"issue":"2","key":"10.1016\/j.micron.2025.103940_bib19","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s00436-007-0684-7","article-title":"Status of tick distribution in Bangladesh, India and Pakistan","volume":"101","author":"Ghosh","year":"2007","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.micron.2025.103940_bib20","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1590\/S1984-29612014042","article-title":"Reassessment of the potential economic impact of cattle parasites in Brazil","volume":"23","author":"Grisi","year":"2014","journal-title":"Rev. Bras. De. Parasitol. Veter.. \u00e1ria"},{"issue":"4","key":"10.1016\/j.micron.2025.103940_bib21","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.ttbdis.2019.03.010","article-title":"Sublethal concentrations of acetylcarvacrol strongly impact oocyte development of engorged female cattle ticks rhipicephalus microplus (Canestrini, 1888) (Acari: Ixodidae)","volume":"10","author":"Konig","year":"2019","journal-title":"Ticks Tick. borne Dis."},{"key":"10.1016\/j.micron.2025.103940_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.micron.2019.102780","article-title":"Low concentrations of acetylcarvacrol induce drastic morphological damages in ovaries of surviving rhipicephalus sanguineus sensu lato ticks (Acari: Ixodidae)","volume":"129","author":"Konig","year":"2020","journal-title":"Micron"},{"issue":"8","key":"10.1016\/j.micron.2025.103940_bib23","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.pt.2018.05.005","article-title":"Strategies to optimize the efficacy of anthelmintic drugs in ruminants","volume":"34","author":"Lanusse","year":"2018","journal-title":"Trends Parasitol."},{"issue":"5","key":"10.1016\/j.micron.2025.103940_bib24","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.parint.2017.05.005","article-title":"The effectiveness of a fixed-dose combination pour-on formulation of 1.25% fipronil and 2.5% fluazuron against economically important ectoparasites and associated pharmacokinetics in cattle","volume":"66","author":"Lopes","year":"2017","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.micron.2025.103940_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2021.109596","article-title":"Assessment of lipid profile in fat body and eggs of rhipicephalus microplus engorged females exposed to (e)-cinnamaldehyde and \u03b1-bisabolol, potential acaricide compounds","volume":"300","author":"Marchesini","year":"2021","journal-title":"Vet. Parasitol."},{"issue":"2","key":"10.1016\/j.micron.2025.103940_bib26","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s00436-013-3694-7","article-title":"Determination of the susceptibility of unengorged larvae and engorged females of rhipicephalus microplus (Acari: Ixodidae) to different methods of dissolving thymol","volume":"113","author":"Matos","year":"2014","journal-title":"Parasitol. Res."},{"issue":"2","key":"10.1016\/j.micron.2025.103940_bib27","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.ttbdis.2018.11.003","article-title":"Thymol action on cells and tissues of the synganglia and salivary glands of rhipicephalus sanguineus sensu lato females (Acari: Ixodidae)","volume":"10","author":"Matos","year":"2019","journal-title":"Ticks Tick. borne Dis."},{"issue":"1","key":"10.1016\/j.micron.2025.103940_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.ttbdis.2019.101308","article-title":"Thymol: effects on reproductive biology and gene's organ morphology in rhipicephalus sanguineus sensu lato engorged females (Acari: Ixodidae)","volume":"11","author":"Matos","year":"2020","journal-title":"Ticks Tick. borne Dis."},{"issue":"4","key":"10.1016\/j.micron.2025.103940_bib29","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ttbdis.2012.03.008","article-title":"Action of permethrin on rhipicephalus sanguineus (Latreille, 1806)(Acari: Ixodidae) semi-engorged females: Morpho-physiological evaluation of salivary glands","volume":"3","author":"Nodari","year":"2012","journal-title":"Ticks Tick. borne Dis."},{"key":"10.1016\/j.micron.2025.103940_bib30","first-page":"18","article-title":"Morpho-ultrastructural alterations in the salivary glands of semi-engorged riphicephalus sanguineus sl females subjected to permethrin","volume":"3","author":"Nodari","year":"2017","journal-title":"Emergent Life Sci. Res."},{"key":"10.1016\/j.micron.2025.103940_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.exppara.2019.107774","article-title":"Evaluation of synergism and development of a formulation with thymol, carvacrol and eugenol for rhipicephalus microplus control","volume":"207","author":"Novato","year":"2019","journal-title":"Exp. Parasitol."},{"issue":"3-4","key":"10.1016\/j.micron.2025.103940_bib32","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.vetpar.2015.08.021","article-title":"evaluation of the combined effect of thymol, carvacrol and (e)-cinnamaldehyde on amblyomma sculptum (Acari: Ixodidae) and dermacentor nitens (Acari: Ixodidae) larvae","volume":"212","author":"Novato","year":"2015","journal-title":"Vet. Parasitol."},{"issue":"1","key":"10.1016\/j.micron.2025.103940_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10493-020-00489-z","article-title":"Botanical acaricides and repellents in tick control: current status and future directions","volume":"81","author":"Nwanade","year":"2020","journal-title":"Exp. Appl. Acarol."},{"issue":"2","key":"10.1016\/j.micron.2025.103940_bib34","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.exppara.2004.12.016","article-title":"Morphological characterization of the ovary and oocytes vitellogenesis of the tick rhipicephalus sanguineus (Latreille, 1806)(Acari: Ixodidae)","volume":"110","author":"de Oliveira","year":"2005","journal-title":"Exp. Parasitol."},{"issue":"7","key":"10.1016\/j.micron.2025.103940_bib35","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1016\/j.fct.2008.03.034","article-title":"Evaluation of cytotoxic effects of fipronil on ovaries of semi-engorged rhipicephalus sanguineus (Latreille, 1806)(Acari: Ixodidae) tick female","volume":"46","author":"de Oliveira","year":"2008","journal-title":"Food Chem. Toxicol."},{"issue":"6","key":"10.1016\/j.micron.2025.103940_bib36","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/j.fct.2009.02.019","article-title":"Action of the chemical agent fipronil on the reproductive process of semi-engorged females of the tick rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae). ultrastructural evaluation of ovary cells","volume":"47","author":"de Oliveira","year":"2009","journal-title":"Food Chem. Toxicol."},{"issue":"2","key":"10.1016\/j.micron.2025.103940_bib37","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s00436-015-4814-3","article-title":"Dinotefuran-induced morphophysiological changes in the ovaries and midgut of semi-engorged females rhipicephalus sanguineus latreille, 1806 (Acari: Ixodidae) ticks","volume":"115","author":"de Oliveira","year":"2016","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.micron.2025.103940_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2021.109584","article-title":"Effects of acaricidal essential oils from lippia sidoides and lippia gracilis and their main components on vitellogenesis in rhipicephalus microplus (Canestrini, 1888) (Acari: Ixodidae)","volume":"299","author":"Penha","year":"2021","journal-title":"Vet. Parasitol."},{"issue":"2","key":"10.1016\/j.micron.2025.103940_bib39","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s10493-017-0109-y","article-title":"Detrimental effect of deltamethrin on the central nervous system (synganglion) of rhipicephalus sanguineus ticks","volume":"71","author":"Pereira","year":"2017","journal-title":"Exp. Appl. Acarol."},{"issue":"1-2","key":"10.1016\/j.micron.2025.103940_bib40","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.vetpar.2014.01.012","article-title":"First report of fluazuron resistance in rhipicephalus microplus: a field tick population resistant to six classes of acaricides","volume":"201","author":"Reck","year":"2014","journal-title":"Vet. Parasitol."},{"issue":"7","key":"10.1016\/j.micron.2025.103940_bib41","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1002\/jemt.23693","article-title":"Cytotoxic effects of satureja Montana L. Essential oil on oocytes of engorged rhipicephalus microplus female ticks (Acari: Ixodidae)","volume":"84","author":"Reis","year":"2021","journal-title":"Microsc. Res. Tech."},{"issue":"1","key":"10.1016\/j.micron.2025.103940_bib42","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00436-017-5677-6","article-title":"Strategies for the control of rhipicephalus microplus ticks in a world of conventional acaricide and macrocyclic lactone resistance","volume":"117","author":"Rodriguez-Vivas","year":"2018","journal-title":"Parasitol. Res."},{"issue":"3","key":"10.1016\/j.micron.2025.103940_bib43","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.fct.2009.12.016","article-title":"Permethrin-induced morphological changes in oocytes of rhipicephalus sanguineus (Acari: Ixodidae) semi-engorged females","volume":"48","author":"Roma","year":"2010","journal-title":"Food Chem. Toxicol."},{"issue":"3","key":"10.1016\/j.micron.2025.103940_bib44","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s10493-010-9401-9","article-title":"Cytotoxic effects of permethrin in oocytes of rhipicephalus sanguineus (Acari: Ixodidae) fully engorged females: I. Direct or indirect action of the acaricide in germ cells?","volume":"53","author":"Roma","year":"2011","journal-title":"Exp. Appl. Acarol."},{"issue":"3-4","key":"10.1016\/j.micron.2025.103940_bib45","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.vetpar.2013.02.025","article-title":"Neurotoxic action of permethrin in rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) female ticks. Morphological and cytochemical evaluation of the central nervous system","volume":"196","author":"Roma","year":"2013","journal-title":"Vet. Parasitol."},{"issue":"3-4","key":"10.1016\/j.micron.2025.103940_bib46","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.vetpar.2004.09.020","article-title":"Morphological, histological, and ultrastructural studies of the ovary of the cattle-tick boophilus microplus (Canestrini, 1887) (Acari: Ixodidae)","volume":"129","author":"Saito","year":"2005","journal-title":"Vet. Parasitol."},{"issue":"3","key":"10.1016\/j.micron.2025.103940_bib47","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0955-0674(99)80054-4","article-title":"Structure and function of the nucleolus","volume":"11","author":"Scheer","year":"1999","journal-title":"Curr. Opin. Cell Biol."},{"issue":"3","key":"10.1016\/j.micron.2025.103940_bib48","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1007\/s00436-022-07454-2","article-title":"Effect of the formulation with fipronil and fluazuron on the reproductive biology and ovaries histopathology of rhipicephalus microplus engorged females","volume":"121","author":"Secchis","year":"2022","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.micron.2025.103940_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2023.109938","article-title":"Thymol and eugenol against rhipicephalus sanguineus sensu lato engorged females: biological, histopathological and bioinformatic analysis","volume":"319","author":"Silva","year":"2023","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.micron.2025.103940_bib50","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.micron.2018.09.015","article-title":"Effects of carvacrol on oocyte development in semi-engorged rhipicephalus sanguineus sensu lato females ticks (Acari: Ixodidae)","volume":"116","author":"de Souza","year":"2019","journal-title":"Micron"},{"issue":"1","key":"10.1016\/j.micron.2025.103940_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep12690","article-title":"Enhanced cuticular penetration as the mechanism for synergy of insecticidal constituents of rosemary essential oil in trichoplusia ni","volume":"5","author":"Tak","year":"2015","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.micron.2025.103940_bib52","doi-asserted-by":"crossref","first-page":"821","DOI":"10.3390\/pathogens10070821","article-title":"Rhipicephalus tick: a contextual review for Southeast Asia","volume":"10","author":"Tan","year":"2021","journal-title":"Pathogens"},{"issue":"1","key":"10.1016\/j.micron.2025.103940_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.ttbdis.2021.101874","article-title":"Combination of cypermethrin and thymol for control of rhipicephalus microplus: efficacy evaluation and description of an action mechanism","volume":"13","author":"Tavares","year":"2022","journal-title":"Ticks Tick. borne Dis."},{"issue":"3","key":"10.1016\/j.micron.2025.103940_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.ttbdis.2022.101929","article-title":"Effects of carvacrol and thymol on the antioxidant and detoxifying enzymes of rhipicephalus microplus (Acari: Ixodidae)","volume":"13","author":"Tavares","year":"2022","journal-title":"Ticks Tick. borne Dis."},{"issue":"4","key":"10.1016\/j.micron.2025.103940_bib55","article-title":"Acaricidal potential of various plant natural products: a review","volume":"15","author":"Upadhyay","year":"2021","journal-title":"Int. J. Green. Pharm. (IJGP)"},{"issue":"6","key":"10.1016\/j.micron.2025.103940_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.ttbdis.2021.101816","article-title":"Binary combinations of thymol, carvacrol and eugenol for amblyomma sculptum control: evaluation of in vitro synergism and effectiveness under semi-field conditions","volume":"12","author":"Vale","year":"2021","journal-title":"Ticks Tick. borne Dis."},{"issue":"5","key":"10.1016\/j.micron.2025.103940_bib57","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1007\/s00436-012-3031-6","article-title":"Cytotoxic effects of andiroba oil (Carapa guianensis) in reproductive system of rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) semi-engorged females","volume":"111","author":"Vendramini","year":"2012","journal-title":"Parasitol. Res."},{"issue":"15","key":"10.1016\/j.micron.2025.103940_bib58","doi-asserted-by":"crossref","first-page":"4900","DOI":"10.1021\/acs.jcim.3c00625","article-title":"Understanding drug skin permeation enhancers using molecular dynamics simulations","volume":"63","author":"Wennberg","year":"2023","journal-title":"J. Chem. Inf. Model."},{"issue":"1","key":"10.1016\/j.micron.2025.103940_bib59","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1023\/A:1015813803205","article-title":"Terpenes and the lipid\u2013protein\u2013partitioning theory of skin penetration enhancement","volume":"8","author":"Williams","year":"1991","journal-title":"Pharm. Res."}],"container-title":["Micron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968432825001581?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968432825001581?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T21:59:01Z","timestamp":1773179941000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968432825001581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":59,"alternative-id":["S0968432825001581"],"URL":"https:\/\/doi.org\/10.1016\/j.micron.2025.103940","relation":{},"ISSN":["0968-4328"],"issn-type":[{"value":"0968-4328","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thymol enhances the acaricidal effects of cypermethrin through the disruption of oocyte development in Rhipicephalus microplus (Acari: Ixodidae)","name":"articletitle","label":"Article Title"},{"value":"Micron","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.micron.2025.103940","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103940"}}