{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:42:21Z","timestamp":1791315741310,"version":"4.3.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Deutsche Forschungsgemeinschaft DFG","award":["SCHU 2394\/1-1"],"award-info":[{"award-number":["SCHU 2394\/1-1"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Microbiological Methods"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.mimet.2010.11.004","type":"journal-article","created":{"date-parts":[[2010,11,14]],"date-time":"2010-11-14T04:16:53Z","timestamp":1289708213000},"page":"101-108","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["Real-time impedance analysis of host cell response to meningococcal infection"],"prefix":"10.1016","volume":"84","author":[{"given":"H.","family":"Slanina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"K\u00f6nig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Claus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Frosch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Schubert-Unkmeir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mimet.2010.11.004_bb0005","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.chembiol.2009.05.011","article-title":"Kinetic cell-based morphological screening: prediction of mechanism of compound action and off-target effects","volume":"16","author":"Abassi","year":"2009","journal-title":"Chem. Biol."},{"key":"10.1016\/j.mimet.2010.11.004_bb0010","doi-asserted-by":"crossref","first-page":"35371","DOI":"10.1074\/jbc.273.52.35371","article-title":"Bacterial lipopolysaccharide disrupts endothelial monolayer integrity and survival signaling events through caspase cleavage of adherens junction proteins","volume":"273","author":"Bannerman","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.mimet.2010.11.004_bb0015","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.micinf.2009.08.014","article-title":"Host cell death machinery as a target for bacterial pathogens","volume":"11","author":"Bohme","year":"2009","journal-title":"Microbes Infect."},{"key":"10.1016\/j.mimet.2010.11.004_bb0020","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0163-4453(87)92703-4","article-title":"Septicaemia due to Neisseria lactamica\u2014initial confusion with Neisseria meningitidis","volume":"15","author":"Brown","year":"1987","journal-title":"J. Infect."},{"key":"10.1016\/j.mimet.2010.11.004_bb0025","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1016\/S0041-0101(01)00159-3","article-title":"The cytolethal distending toxins induce DNA damage and cell cycle arrest","volume":"39","author":"Cortes-Bratti","year":"2001","journal-title":"Toxicon"},{"key":"10.1016\/j.mimet.2010.11.004_bb0030","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1093\/clinids\/13.2.216","article-title":"Neisseria lactamica meningitis following skull trauma","volume":"13","author":"Denning","year":"1991","journal-title":"Rev. Infect. Dis."},{"key":"10.1016\/j.mimet.2010.11.004_bb0035","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.bbrc.2005.07.085","article-title":"Divergent effects of zinc depletion in brain vs non-brain endothelial cells","volume":"335","author":"Di Cello","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mimet.2010.11.004_bb0040","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0882-4010(95)90085-3","article-title":"Investigations into the molecular basis of meningococcal toxicity for human endothelial and epithelial cells: the synergistic effect of LPS and pili","volume":"18","author":"Dunn","year":"1995","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.mimet.2010.11.004_bb0045","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.toxicon.2009.12.008","article-title":"Embryotoxic effects of the marine biotoxin okadaic acid on murine embryonic stem cells","volume":"55","author":"Ehlers","year":"2010","journal-title":"Toxicon"},{"key":"10.1016\/j.mimet.2010.11.004_bb0050","doi-asserted-by":"crossref","first-page":"6467","DOI":"10.1128\/IAI.00644-06","article-title":"Comparison of the inflammatory responses of human meningeal cells following challenge with Neisseria lactamica and with Neisseria meningitidis","volume":"74","author":"Fowler","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.mimet.2010.11.004_bb0055","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1038\/cdd.2009.44","article-title":"Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes","volume":"16","author":"Galluzzi","year":"2009","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.mimet.2010.11.004_bb0060","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1023\/A:1012485506972","article-title":"Molecular mechanisms of bacteria induced apoptosis","volume":"6","author":"Grassme","year":"2001","journal-title":"Apoptosis"},{"key":"10.1016\/j.mimet.2010.11.004_bb0065","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/S0022-3476(78)81264-5","article-title":"Neisseria lactamica meningitis","volume":"93","author":"Greenberg","year":"1978","journal-title":"J. Pediatr."},{"key":"10.1016\/j.mimet.2010.11.004_bb0070","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1056\/NEJM197808312990924","article-title":"Meningitis caused by Neisseria lactamica","volume":"299","author":"Hansman","year":"1978","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.mimet.2010.11.004_bb0075","first-page":"269","article-title":"Lipopolysaccharide-mediated bovine endothelial cell injury in vitro","volume":"48","author":"Harlan","year":"1983","journal-title":"Lab Invest."},{"key":"10.1016\/j.mimet.2010.11.004_bb0080","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1128\/jcm.9.2.186-188.1979","article-title":"Serotypes of Neisseria meningitidis isolated from patients in Norway during the first six months of 1978","volume":"9","author":"Holten","year":"1979","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.mimet.2010.11.004_bb0085","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1096\/fj.06-6675com","article-title":"Neisseria gonorrhoeae infection causes a G1 arrest in human epithelial cells","volume":"21","author":"Jones","year":"2007","journal-title":"FASEB J."},{"key":"10.1016\/j.mimet.2010.11.004_bb0090","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.placenta.2010.02.008","article-title":"New technology for investigating trophoblast function","volume":"31","author":"Keogh","year":"2010","journal-title":"Placenta"},{"key":"10.1016\/j.mimet.2010.11.004_bb0095","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1038\/nature07952","article-title":"Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment","volume":"459","author":"Kim","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.mimet.2010.11.004_bb0100","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/0140-6736(91)91297-8","article-title":"Point mutation in meningococcal por A gene associated with increased endemic disease","volume":"337","author":"McGuinness","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.mimet.2010.11.004_bb0105","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1083\/jcb.200412151","article-title":"CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells","volume":"170","author":"Muenzner","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.mimet.2010.11.004_bb0110","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1078\/1438-4221-00125","article-title":"Modification of host cell apoptosis by viral and bacterial pathogens","volume":"291","author":"Muller","year":"2001","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.mimet.2010.11.004_bb0115","doi-asserted-by":"crossref","first-page":"5074","DOI":"10.1128\/iai.65.12.5074-5081.1997","article-title":"Invasion of brain microvascular endothelial cells by group B streptococci","volume":"65","author":"Nizet","year":"1997","journal-title":"Infect. Immun."},{"key":"10.1016\/j.mimet.2010.11.004_bb0120","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.2460\/ajvr.1989.50.09.1633","article-title":"Direct effects of Pasteurella haemolytica lipopolysaccharide on bovine pulmonary endothelial cells in vitro","volume":"50","author":"Paulsen","year":"1989","journal-title":"Am. J. Vet. Res."},{"key":"10.1016\/j.mimet.2010.11.004_bb0125","series-title":"RTCA SP Instrument Operator's Manual","first-page":"14","article-title":"Introduction of the RTCA SP instrument","author":"Roche","year":"2008"},{"key":"10.1016\/j.mimet.2010.11.004_bb0130","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1128\/jcm.17.5.934-935.1983","article-title":"Neisseria lactamica septicemia in an immunocompromised patient","volume":"17","author":"Schifman","year":"1983","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.mimet.2010.11.004_bb0135","doi-asserted-by":"crossref","first-page":"e1000874","DOI":"10.1371\/journal.ppat.1000874","article-title":"Neisseria meningitidis induces brain microvascular endothelial cell detachment from the matrix and cleavage of occludin: a role for MMP-8","volume":"6","author":"Schubert-Unkmeir","year":"2010","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.mimet.2010.11.004_bb0140","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1128\/IAI.01267-09","article-title":"Entry of Neisseria meningitidis into mammalian cells requires the Src family protein tyrosine kinases","volume":"78","author":"Slanina","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.mimet.2010.11.004_bb0145","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/33046","article-title":"Meningitis bacterium is viable without endotoxin","volume":"392","author":"Steeghs","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.mimet.2010.11.004_bb0150","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0165-5728(97)00036-2","article-title":"Selective expression of adhesion molecules on human brain microvascular endothelial cells","volume":"76","author":"Stins","year":"1997","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.mimet.2010.11.004_bb0155","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1006\/mpat.2000.0406","article-title":"Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells","volume":"30","author":"Stins","year":"2001","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.mimet.2010.11.004_bb0160","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1046\/j.1365-2958.2002.03222.x","article-title":"Fibronectin mediates Opc-dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells","volume":"46","author":"Unkmeir","year":"2002","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.mimet.2010.11.004_bb0165","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.dental.2009.08.007","article-title":"Real-time xCELLigence impedance analysis of the cytotoxicity of dental composite components on human gingival fibroblasts","volume":"26","author":"Urcan","year":"2010","journal-title":"Dent. Mater."},{"key":"10.1016\/j.mimet.2010.11.004_bb0170","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1111\/j.1365-2958.1991.tb00807.x","article-title":"The role of pili in the interactions of pathogenic Neisseria with cultured human endothelial cells","volume":"5","author":"Virji","year":"1991","journal-title":"Mol. Microbiol."},{"issue":"Suppl 1","key":"10.1016\/j.mimet.2010.11.004_bb0175","first-page":"121","article-title":"The comparison of impedance-based method of cell proliferation monitoring with commonly used metabolic-based techniques","volume":"30","author":"Vistejnova","year":"2009","journal-title":"Neuro Endocrinol. Lett."},{"key":"10.1016\/j.mimet.2010.11.004_bb0180","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev.micro.53.1.155","article-title":"The induction of apoptosis by bacterial pathogens","volume":"53","author":"Weinrauch","year":"1999","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.mimet.2010.11.004_bb0185","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1128\/jcm.4.3.214-215.1976","article-title":"Septicemia due to Neisseria lactamica","volume":"4","author":"Wilson","year":"1976","journal-title":"J. Clin. Microbiol."}],"container-title":["Journal of Microbiological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167701210003830?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167701210003830?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T23:42:16Z","timestamp":1759102936000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167701210003830"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["S0167701210003830"],"URL":"https:\/\/doi.org\/10.1016\/j.mimet.2010.11.004","relation":{},"ISSN":["0167-7012"],"issn-type":[{"value":"0167-7012","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Real-time impedance analysis of host cell response to meningococcal infection","name":"articletitle","label":"Article Title"},{"value":"Journal of Microbiological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mimet.2010.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}