{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T05:23:56Z","timestamp":1793942636303,"version":"4.8.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T00:00:00Z","timestamp":1580256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007797","name":"University of Helsinki","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007797","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Microbiological Methods"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.mimet.2020.105857","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T22:30:05Z","timestamp":1580337005000},"page":"105857","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["A platform for studying the transfer of Chlamydia pneumoniae infection between respiratory epithelium and phagocytes"],"prefix":"10.1016","volume":"171","author":[{"given":"Maarit","family":"Kortesoja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raluca Elena","family":"Trofin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leena","family":"Hanski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mimet.2020.105857_bb0005","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.micinf.2010.04.008","article-title":"Chlamydial infection of monocytes stimulates IL-1\u03b2 secretion through activation of the NLRP3 inflammasome","volume":"12","author":"Abdul-Sater","year":"2010","journal-title":"Microbes Infect."},{"key":"10.1016\/j.mimet.2020.105857_bb0010","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1128\/IAI.67.3.1445-1449.1999","article-title":"Chlamydia pneumoniae infection in human monocytes","volume":"67","author":"Airenne","year":"1999","journal-title":"Infect. Immun."},{"key":"10.1016\/j.mimet.2020.105857_bb0015","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.12845","article-title":"Extracellular HtrA serine proteases: an emerging new strategy in bacterial pathogenesis","volume":"20","author":"Backert","year":"2018","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0020","article-title":"Definitions and guidelines for research on antibiotic persistence","volume":"1","author":"Balaban","year":"2019","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0025","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s004300050071","article-title":"Identification and localization of Chlamydia pneumoniae in the Alzheimer\u2019s brain","volume":"187","author":"Balin","year":"1998","journal-title":"Med. Microbiol. Immunol. (Berl.)"},{"key":"10.1016\/j.mimet.2020.105857_bb0030","series-title":"Chlamydia pneumoniae as an etiologic agent for late-onset alzheimer\u2019s disease","author":"Balin PhD","year":"2017"},{"key":"10.1016\/j.mimet.2020.105857_bb0035","doi-asserted-by":"crossref","DOI":"10.1615\/CritRevImmunol.v29.i4.10","article-title":"Chlamydial infection of immune cells: altered function and implications for disease","volume":"29","author":"Beagley","year":"2009","journal-title":"Crit. Rev. Immunol."},{"key":"10.1016\/j.mimet.2020.105857_bb0040","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0021-9150(00)00758-9","article-title":"Chlamydia pneumoniae infection accelerates hyperlipidemia induced atherosclerotic lesion development in C57BL\/6J mice","volume":"158","author":"Blessing","year":"2001","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.mimet.2020.105857_bb0045","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s00401-007-0252-3","article-title":"Detection of amyloid beta aggregates in the brain of BALB\/c mice after Chlamydia pneumoniae infection","volume":"114","author":"Boelen","year":"2007","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.mimet.2020.105857_bb0050","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/nrmicro796","article-title":"Chlamydia pneumoniae\u2014an infectious risk factor for atherosclerosis?","volume":"2","author":"Campbell","year":"2004","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.micpath.2014.03.001","article-title":"MAPK\u2013PPAR\u03b1\/\u03b3 signal transduction pathways are involved in Chlamydia pneumoniae-induced macrophage-derived foam cell formation","volume":"69","author":"Cheng","year":"2014","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.mimet.2020.105857_bb0060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0046949","article-title":"Actin recruitment to the Chlamydia inclusion is spatiotemporally regulated by a mechanism that requires host and bacterial factors","volume":"7","author":"Chin","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.mimet.2020.105857_bb0065","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1046\/j.1462-5822.2002.00203.x","article-title":"Identification of MEK-and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells","volume":"4","author":"Coombes","year":"2002","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0070","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3390\/microorganisms7050140","article-title":"Chlamydia trachomatis and Chlamydia pneumoniae interaction with the host: latest advances and future prospective","volume":"7","author":"Di Pietro","year":"2019","journal-title":"Microorganisms"},{"key":"10.1016\/j.mimet.2020.105857_bb0075","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nrmicro.2016.30","article-title":"Chlamydia cell biology and pathogenesis","volume":"14","author":"Elwell","year":"2016","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0080","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/378658","article-title":"Chlamydia pneumoniae-mediated inflammation in atherosclerosis: a meta-analysis","volume":"2015","author":"Filardo","year":"2015","journal-title":"Mediat. Inflamm."},{"issue":"73","key":"10.1016\/j.mimet.2020.105857_bb0085","article-title":"Membrane vesicle production by Chlamydia trachomatis as an adaptive response","volume":"4","author":"Frohlich","year":"2014","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0090","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2018.00224","article-title":"Can an infection hypothesis explain the beta amyloid hypothesis of Alzheimer\u2019s disease?","volume":"10","author":"Fulop","year":"2018","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.mimet.2020.105857_bb0095","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.micpath.2007.10.002","article-title":"Apolipoprotein E4 enhances attachment of Chlamydophila (Chlamydia) pneumoniae elementary bodies to host cells","volume":"44","author":"G\u00e9rard","year":"2008","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.mimet.2020.105857_bb0100","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1161\/01.CIR.103.3.351","article-title":"Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic treatment","volume":"103","author":"Gieffers","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.mimet.2020.105857_bb0105","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1183\/09031936.04.00093304","article-title":"Phagocytes transmit Chlamydia pneumoniae from the lungs to the vasculature","volume":"23","author":"Gieffers","year":"2004","journal-title":"Eur. Respir. J."},{"issue":"14","key":"10.1016\/j.mimet.2020.105857_bb0110","article-title":"The impact of active metabolism on Chlamydia trachomatis elementary body transcript profile and infectivity","volume":"200","author":"Grieshaber","year":"2018","journal-title":"J. Bacteriol.JB."},{"key":"10.1016\/j.mimet.2020.105857_bb0115","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3390\/microorganisms4040043","article-title":"Lead discovery strategies for identification of Chlamydia pneumoniae inhibitors","volume":"4","author":"Hanski","year":"2016","journal-title":"Microorganisms"},{"key":"10.1016\/j.mimet.2020.105857_bb0120","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0157306","article-title":"Amphipathic \u03b2 2, 2-amino acid derivatives suppress infectivity and disrupt the intracellular replication cycle of Chlamydia pneumoniae","volume":"11","author":"Hanski","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.mimet.2020.105857_bb0125","series-title":"Natural Product Communications11:1934578X1601101125","article-title":"Mint flavorings from candies inhibit the infectivity of Chlamydia pneumoniae","author":"Hanski","year":"2016"},{"key":"10.1016\/j.mimet.2020.105857_bb0130","article-title":"GroEL1, from Chlamydia pneumoniae, induces vascular adhesion molecule 1 expression by p37AUF1 in endothelial cells and hypercholesterolemic rabbit","volume":"7","author":"Huang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.mimet.2020.105857_bb0135","doi-asserted-by":"crossref","first-page":"11430","DOI":"10.1073\/pnas.0703218104","article-title":"Mechanisms of host cell exit by the intracellular bacterium Chlamydia","volume":"104","author":"Hybiske","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mimet.2020.105857_bb0140","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.bbrc.2014.08.128","article-title":"Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages","volume":"452","author":"Itoh","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mimet.2020.105857_bb0145","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1006\/mpat.2000.0420","article-title":"Chlamydia pneumoniae facilitates monocyte adhesion to endothelial and smooth muscle cells","volume":"30","author":"Kaul","year":"2001","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.mimet.2020.105857_bb0150","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.freeradbiomed.2018.12.019","article-title":"Impact of dibenzocyclooctadiene lignans from Schisandra chinensis on the redox status and activation of human innate immune system cells","volume":"131","author":"Kortesoja","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.mimet.2020.105857_bb0155","doi-asserted-by":"crossref","first-page":"6615","DOI":"10.1128\/IAI.72.11.6615-6621.2004","article-title":"Differences in cell activation by Chlamydophila pneumoniae and Chlamydia trachomatis infection in human endothelial cells","volume":"72","author":"Kr\u00fcll","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.mimet.2020.105857_bb0160","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1160\/TH05-04-0261","article-title":"Chlamydophila pneumoniae","volume":"94","author":"Kr\u00fcll","year":"2005","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.mimet.2020.105857_bb0165","series-title":"Chlamydia. Bergey\u2019s Manual of Systematics of Archaea and Bacteria1\u201328","author":"Kuo","year":"2015"},{"key":"10.1016\/j.mimet.2020.105857_bb0170","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/infdis\/162.3.755","article-title":"A sensitive cell line, HL cells, for isolation and propagation of Chlamydia pneumoniae strain TWAR","volume":"162","author":"Kuo","year":"1990","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.mimet.2020.105857_bb0175","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1128\/CMR.8.4.451","article-title":"Chlamydia pneumoniae (TWAR)","volume":"8","author":"Kuo","year":"1995","journal-title":"Clin. Microbiol. Rev."},{"issue":"2","key":"10.1016\/j.mimet.2020.105857_bb0180","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.micinf.2018.10.007","article-title":"Immunobiology of monocytes and macrophages during Chlamydia trachomatis infection","volume":"21","author":"Lausen","year":"2019","journal-title":"Microbes Infect."},{"key":"10.1016\/j.mimet.2020.105857_bb0185","doi-asserted-by":"crossref","DOI":"10.1186\/s12974-014-0217-0","article-title":"Chlamydia pneumoniae infection of monocytes in vitro stimulates innate and adaptive immune responses relevant to those in Alzheimer\u2019s disease","volume":"11","author":"Lim","year":"2014","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.mimet.2020.105857_bb0190","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1086\/315349","article-title":"Monocyte-endothelial cell coculture enhances infection of endothelial cells with Chlamydia pneumoniae","volume":"181","author":"Lin","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.mimet.2020.105857_bb0195","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0197-4580(03)00127-1","article-title":"Chlamydia pneumoniae induces alzheimer-like amyloid plaques in brains of BALB\/c mice","volume":"25","author":"Little","year":"2004","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.mimet.2020.105857_bb0200","first-page":"2423","article-title":"Early atherosclerotic plaques show evidence of infection by Chlamydia pneumoniae","author":"Luque","year":"2012","journal-title":"Front. Biosci."},{"key":"10.1016\/j.mimet.2020.105857_bb0205","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/S0735-1097(98)00016-3","article-title":"Endovascular presence of viable Chlamydia pneumoniae is a common phenomenon in coronary artery disease","volume":"31","author":"Maass","year":"1998","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0210","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ijmm.2006.11.004","article-title":"Differential effects of Chlamydia pneumoniae infection on cytokine levels in human T lymphocyte-and monocyte-derived cell cultures","volume":"297","author":"Mamata","year":"2007","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0215","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1086\/515280","article-title":"Evidence of systemic dissemination of Chlamydia pneumoniae via macrophages in the mouse","volume":"177","author":"Moazed","year":"1998","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.mimet.2020.105857_bb0220","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/j.1365-2958.2007.06050.x","article-title":"The Chlamydia outer membrane protein OmcB is required for adhesion and exhibits biovar-specific differences in glycosaminoglycan binding","volume":"67","author":"Moelleken","year":"2008","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003325","article-title":"The Chlamydia pneumoniae invasin protein Pmp21 recruits the EGF receptor for host cell entry","volume":"9","author":"M\u00f6lleken","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.mimet.2020.105857_bb0230","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.bbrc.2004.10.155","article-title":"Effects of COX-2 inhibitors on ROS produced by Chlamydia pneumoniae-primed human promonocytic cells (THP-1)","volume":"325","author":"Mouithys-Mickalad","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mimet.2020.105857_bb0235","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.ijantimicag.2005.11.010","article-title":"Effects of sustained antibiotic bactericidal treatment on Chlamydia trachomatis-infected epithelial-like cells (HeLa) and monocyte-like cells (THP-1 and U-937)","volume":"27","author":"Mpiga","year":"2006","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.mimet.2020.105857_bb0240","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1365-3083.2006.01734.x","article-title":"Sustained Interleukin-6 and Interleukin-8 expression following infection with Chlamydia trachomatis serovar L2 in a HeLa\/THP-1 cell co-culture model","volume":"63","author":"Mpiga","year":"2006","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.mimet.2020.105857_bb0245","doi-asserted-by":"crossref","first-page":"S505","DOI":"10.1086\/315627","article-title":"Chlamydia pneumoniae\u2014induced atherosclerosis in a rabbit model","volume":"181","author":"Muhlestein","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.mimet.2020.105857_bb0250","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3389\/fcimb.2013.00100","article-title":"The protease inhibitor JO146 demonstrates a critical role for CtHtrA for Chlamydia trachomatis reversion from penicillin persistence","volume":"3","author":"Ong","year":"2013","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0255","doi-asserted-by":"crossref","first-page":"3101","DOI":"10.3389\/fmicb.2018.03101","article-title":"Chlamydia persistence: a survival strategy to evade antimicrobial effects in-vitro and in-vivo","volume":"9","author":"Panzetta","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0260","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1600-0463.2009.02557.x","article-title":"Quantification of Chlamydia pneumoniae in cultured human macrophages and HL cells: comparison of real-time PCR, immunofluorescence and ELISA methods","volume":"118","author":"Poikonen","year":"2010","journal-title":"Apmis"},{"key":"10.1016\/j.mimet.2020.105857_bb0265","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1086\/368267","article-title":"Cell-to-cell contact of human monocytes with infected arterial smooth-muscle cells enhances growth of Chlamydia pneumoniae","volume":"187","author":"Puolakkainen","year":"2003","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.mimet.2020.105857_bb0270","doi-asserted-by":"crossref","first-page":"4620","DOI":"10.1128\/IAI.73.8.4620-4625.2005","article-title":"Chlamydia pneumoniae uses the mannose 6-phosphate\/insulin-like growth factor 2 receptor for infection of endothelial cells","volume":"73","author":"Puolakkainen","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.mimet.2020.105857_bb0275","doi-asserted-by":"crossref","first-page":"262","DOI":"10.2174\/1567202615666180717161807","article-title":"Pivotal pathogenic and biomarker role of Chlamydia pneumoniae in neurovascular diseases","volume":"15","author":"Richard","year":"2018","journal-title":"Curr. Neurovasc. Res."},{"key":"10.1016\/j.mimet.2020.105857_bb0280","doi-asserted-by":"crossref","first-page":"4269","DOI":"10.1128\/iai.64.10.4269-4278.1996","article-title":"Temporal analysis of the developing Chlamydia psittaci inclusion by use of fluorescence and electron microscopy","volume":"64","author":"Rockey","year":"1996","journal-title":"Infect. Immun."},{"key":"10.1016\/j.mimet.2020.105857_bb0285","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.bbrc.2004.05.210","article-title":"Cox-2 inhibition abrogates Chlamydia pneumoniae-induced PGE2 and MMP-1 expression","volume":"320","author":"Rupp","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.mimet.2020.105857_bb0290","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3389\/fcell.2016.00067","article-title":"S. Redundancy in the world of MAP kinases: all for one","volume":"4","author":"Saba-El-Leil","year":"2016","journal-title":"Front. Cell Develop. Biol."},{"key":"10.1016\/j.mimet.2020.105857_bb0295","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/S0140-6736(88)90741-6","article-title":"Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction","volume":"332","author":"Saikku","year":"1988","journal-title":"Lancet"},{"key":"10.1016\/j.mimet.2020.105857_bb0300","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/jlb.59.4.555","article-title":"Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1, 25-dihydroxyvitamin D3","volume":"59","author":"Schwende","year":"1996","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.mimet.2020.105857_bb0305","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1128\/mSphere.00412-18","article-title":"The genetic transformation of Chlamydia pneumoniae","volume":"3","author":"Shima","year":"2018","journal-title":"mSphere"},{"key":"10.1016\/j.mimet.2020.105857_bb0310","first-page":"16","article-title":"Histological and ultrastructural findings suggesting an initiating role for Chlamydia pneumoniae in the pathogenesis of atherosclerosis","volume":"11","author":"Shor","year":"2000","journal-title":"Cardiovasc. J. South. Afr."},{"key":"10.1016\/j.mimet.2020.105857_bb0315","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s11845-016-1549-9","article-title":"Chlamydia pneumoniae induces interleukin-12 responses in peripheral blood mononuclear cells in asthma and the role of toll like receptor 2 versus 4: A pilot study","volume":"186","author":"Smith-Norowitz","year":"1971","journal-title":"Ir. J. Med. Sci."},{"key":"10.1016\/j.mimet.2020.105857_bb0320","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cellimm.2015.01.007","article-title":"A single infection with Chlamydia pneumoniae is sufficient to exacerbate atherosclerosis in ApoE deficient mice","volume":"294","author":"Sorrentino","year":"2015","journal-title":"Cell. Immunol."},{"issue":"2","key":"10.1016\/j.mimet.2020.105857_bb0325","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3390\/molecules25020294","article-title":"Assaying Chlamydia pneumoniae persistence in monocyte-derived macrophages identifies dibenzocyclooctadiene lignans as phenotypic switchers","volume":"25","author":"Taavitsainen","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.mimet.2020.105857_bb0330","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1128\/JCM.40.2.575-583.2002","article-title":"Development and evaluation of real-time PCR-based fluorescence assays for detection of Chlamydia pneumoniae","volume":"40","author":"Tondella","year":"2002","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.mimet.2020.105857_bb0335","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/ijc.2910260208","article-title":"Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)","volume":"26","author":"Tsuchiya","year":"1980","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.mimet.2020.105857_bb0340","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/s12931-017-0584-z","article-title":"Infection-mediated asthma: etiology, mechanisms and treatment options, with focus on Chlamydia pneumoniae and macrolides","volume":"18","author":"Webley","year":"2017","journal-title":"Respir. Res."},{"key":"10.1016\/j.mimet.2020.105857_bb0345","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/infdis\/171.3.736","article-title":"Systemic dissemination of Chlamydia pneumoniae following intranasal inoculation in mice","volume":"171","author":"Yang","year":"1995","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.mimet.2020.105857_bb0350","series-title":"MAP Kinase Cascades in Antigen Receptor Signaling and Physiology","first-page":"211","author":"Yasuda","year":"2015"},{"key":"10.1016\/j.mimet.2020.105857_bb0355","doi-asserted-by":"crossref","DOI":"10.1093\/femspd\/ftw093","article-title":"Conservation of extrusion as an exit mechanism for Chlamydia","volume":"74","author":"Zuck","year":"2016","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.mimet.2020.105857_bb0360","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.12683","article-title":"Extrusions are phagocytosed and promote Chlamydia survival within macrophages","volume":"19","author":"Zuck","year":"2017","journal-title":"Cell. Microbiol."}],"container-title":["Journal of Microbiological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167701219310498?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167701219310498?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:34Z","timestamp":1759104034000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167701219310498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":72,"alternative-id":["S0167701219310498"],"URL":"https:\/\/doi.org\/10.1016\/j.mimet.2020.105857","relation":{},"ISSN":["0167-7012"],"issn-type":[{"value":"0167-7012","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A platform for studying the transfer of Chlamydia pneumoniae infection between respiratory epithelium and phagocytes","name":"articletitle","label":"Article Title"},{"value":"Journal of Microbiological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mimet.2020.105857","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105857"}}