{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:07:39Z","timestamp":1784552859549,"version":"3.55.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004410","name":"Scientific and Technological Research Council of Turkey","doi-asserted-by":"publisher","award":["3220673"],"award-info":[{"award-number":["3220673"]}],"id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Microbiological Methods"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.mimet.2026.107498","type":"journal-article","created":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T16:42:21Z","timestamp":1775493741000},"page":"107498","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["An improved DiaRD MTB interferon-gamma release assay for the diagnosis of Mycobacterium Tuberculosis infections"],"prefix":"10.1016","volume":"245","author":[{"given":"Riza","family":"Durmaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sedat","family":"Vezir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Ertek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Koroglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bengul","family":"Durmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oguz","family":"Ari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Akyil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130lker","family":"Sahinkesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bar\u0131\u015f","family":"\u00c7ali\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kemal","family":"Sarifakiogullari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mimet.2026.107498_bb0005","author":"Biomerieux"},{"key":"10.1016\/j.mimet.2026.107498_bb0010","author":"Centers for Disease Control and Prevention"},{"key":"10.1016\/j.mimet.2026.107498_bb0015","author":"Centers for Disease Control and Prevention"},{"key":"10.1016\/j.mimet.2026.107498_bb0020","article-title":"Diagnostic accuracy study of STANDARD TB-Feron FIA and STANDARD TB-Feron ELISA tests for tuberculosis infection diagnosis in eastern european setting","volume":"39","author":"Crudu","year":"2025","journal-title":"J. Clin. Tuberc. Mycobact. Dis."},{"key":"10.1016\/j.mimet.2026.107498_bb0025","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ijid.2019.12.012","article-title":"LIOFeron\u00aeTB\/LTBI: A novel and reliable test for LTBI and tuberculosis","volume":"91","author":"Della Bella","year":"2020","journal-title":"Int. J. Infect. Dis."},{"key":"10.1016\/j.mimet.2026.107498_bb0030","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00431-025-05972-6","article-title":"Performance evaluation of the LIOFeron\u00aeTB\/LTBI IGRA for screening of paediatric LTBI and tuberculosis","volume":"184","author":"Della Bella","year":"2025","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.mimet.2026.107498_bb0035","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1128\/IAI.72.4.2412-2415.2004","article-title":"HLA-A2-restricted CD8+-cytotoxic-T-cell responses to novel epitopes in mycobacterium tuberculosis superoxide dismutase, alanine dehydrogenase, and glutamine synthetase","volume":"72","author":"Dong","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.mimet.2026.107498_bb0040","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.pulmoe.2021.07.003","article-title":"First clinical evaluation of the QIAreachTM QuantiFERON-TB for tuberculosis infection and active pulmonary disease","volume":"28","author":"Fukushima","year":"2022","journal-title":"Pulmonology"},{"key":"10.1016\/j.mimet.2026.107498_bb0045","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3343\/alm.2020.40.1.33","article-title":"Performance evaluation of a new automated chemiluminescent Immunoanalyzer-based interferon-gamma releasing assay AdvanSure i3 in comparison with the QuantiFERON-TB gold in-tube assay","volume":"40","author":"Kim","year":"2020","journal-title":"Ann. Lab. Med."},{"key":"10.1016\/j.mimet.2026.107498_bb0050","doi-asserted-by":"crossref","first-page":"439","DOI":"10.4049\/jimmunol.166.1.439","article-title":"Classically restricted human CD8+ t lymphocytes derived from mycobacterium tuberculosis-infected cells: definition of antigenic specificity","volume":"166","author":"Lewinsohn","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.mimet.2026.107498_bb0055","author":"Lionex"},{"key":"10.1016\/j.mimet.2026.107498_bb0060","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1186\/s12889-025-21954-7","article-title":"Comparative evaluation of QuantiFERON-TB gold in-tube plus for mycobacterium tuberculosis infection among adolescents in China","volume":"25","author":"Lu","year":"2025","journal-title":"BMC Public Health"},{"key":"10.1016\/j.mimet.2026.107498_bb0065","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/1744666X.2024.2407550","article-title":"Diagnostic accuracy of QuantiFERON-TB gold plus with chemiluminescence immunoassay: A systematic review and meta-analysis","volume":"21","author":"Mahmoudi","year":"2025","journal-title":"Expert Rev. Clin. Immunol."},{"key":"10.1016\/j.mimet.2026.107498_bb0070","series-title":"Evaluation of Precision of Quantitative Measurement Procedures: Approved Guideline, Third edition","author":"McEnroe","year":"2014"},{"key":"10.1016\/j.mimet.2026.107498_bb0075","doi-asserted-by":"crossref","first-page":"5730","DOI":"10.1073\/pnas.1015153108","article-title":"Rv3615c is a highly immunodominant RD1 (region of difference 1)-dependent secreted antigen specific for mycobacterium tuberculosis infection","volume":"108","author":"Millington","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mimet.2026.107498_bb0080","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.25122","article-title":"Mycobacterium tuberculosis: the mechanism of pathogenicity, immune responses, and diagnostic challenges","volume":"38","author":"Mohammadnabi","year":"2024","journal-title":"J. Clin. Lab. Anal."},{"key":"10.1016\/j.mimet.2026.107498_bb0085","article-title":"Diagnostic accuracy of the STANDARD f TB-feron FIA assay for tuberculosis infection in Vietnam: a cross-sectional study","author":"Nguyen","year":"2025","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.mimet.2026.107498_bb0090","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/s41467-024-45058-9","article-title":"Identification of differentially recognized t cell epitopes in the spectrum of tuberculosis infection","volume":"15","author":"Panda","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mimet.2026.107498_bb0095","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1383098","article-title":"The role of ESAT-6 in tuberculosis immunopathology","volume":"15","author":"Passos","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.mimet.2026.107498_bb0100","author":"Qiagen"},{"key":"10.1016\/j.mimet.2026.107498_bb0105","author":"Qiagen"},{"key":"10.1016\/j.mimet.2026.107498_bb0110","doi-asserted-by":"crossref","DOI":"10.1080\/21505594.2022.2150449","article-title":"Pathogenicity and virulence of mycobacterium tuberculosis","volume":"14","author":"Rahlwes","year":"2023","journal-title":"Virulence"},{"key":"10.1016\/j.mimet.2026.107498_bb0115","doi-asserted-by":"crossref","DOI":"10.1590\/s1678-9946202365013","article-title":"QuantiFERON-TB gold plus and QuantiFERON-TB gold in-tube assays for detecting latent tuberculosis infection in thai healthcare workers","volume":"65","author":"Rudeeaneksin","year":"2023","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"key":"10.1016\/j.mimet.2026.107498_bb0120","doi-asserted-by":"crossref","DOI":"10.4081\/monaldi.2025.3258","article-title":"Interferon-\u03b3 release assay","author":"Sarkar","year":"2025","journal-title":"Monaldi Arch. Chest Dis. Arch. Monaldi Mal. Torace."},{"key":"10.1016\/j.mimet.2026.107498_bb0125","author":"SD Biosensor"},{"key":"10.1016\/j.mimet.2026.107498_bb0130","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.01641-24","article-title":"Preliminary performance of the VIDAS TB-IGRA as an aid in the diagnosis of individuals infected with mycobacterium tuberculosis","volume":"63","author":"Serge Diagbouga","year":"2025","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.mimet.2026.107498_bb0135","article-title":"Diagnostic accuracy and predictive value of the QuantiFERON-TB gold plus assay for tuberculosis in immunocompromised individuals: A prospective TBnet study","volume":"57","author":"Sester","year":"2025","journal-title":"Lancet Reg. Health Eur."},{"key":"10.1016\/j.mimet.2026.107498_bb0140","series-title":"Ministry of Health of Turkey, General Directorate of Public Health, Ankara","author":"Tuberculosis Control in Turkey: 2021 Report","year":"2023"},{"key":"10.1016\/j.mimet.2026.107498_bb0145","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.01486-24","article-title":"Standard e TB-Feron ELISA and standard f TB-Feron FIA positivity rates and agreement with QuantiFERON-TB gold plus among TB high-risk population in Bandung, Indonesia","volume":"63","author":"Turbawaty","year":"2025","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.mimet.2026.107498_bb0150","author":"Van Gemert"},{"key":"10.1016\/j.mimet.2026.107498_bb0155","doi-asserted-by":"crossref","first-page":"13234","DOI":"10.1038\/s41598-020-70204-w","article-title":"Diagnostic benefits of adding EspC, EspF and Rv2348-B to the QuantiFERON gold in-tube antigen combination","volume":"10","author":"Villar-Hern\u00e1ndez","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.mimet.2026.107498_bb0160","author":"Wantai BioPharm"},{"key":"10.1016\/j.mimet.2026.107498_bb0165","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1615\/CritRevImmunol.v26.i4.30","article-title":"Mycobacterium tuberculosis-specific CD8+ t cells and their role in immunity","volume":"26","author":"Woodworth","year":"2006","journal-title":"Crit. Rev. Immunol."},{"key":"10.1016\/j.mimet.2026.107498_bb0170","series-title":"Latent Tuberculosis Infection: Updated and Consolidated Guidelines for Programmatic Management","author":"World Health Organization","year":"2018"},{"key":"10.1016\/j.mimet.2026.107498_bb0175","author":"World Health Organization"},{"key":"10.1016\/j.mimet.2026.107498_bb0180","series-title":"Global tuberculosis report 2025","author":"World Health Organization","year":"2025"},{"key":"10.1016\/j.mimet.2026.107498_bb0185","author":"World Health Organization"},{"key":"10.1016\/j.mimet.2026.107498_bb0190","series-title":"Manual of Molecular and Clinical Laboratory Immunology","first-page":"318","article-title":"Interferon gamma release assays for tuberculosis diagnosis","author":"Zavala","year":"2024"},{"key":"10.1016\/j.mimet.2026.107498_bb0195","first-page":"170","article-title":"The diagnosis of latent tuberculosis infection (LTBI): currently available tests, future developments, and perspectives to eliminate tuberculosis (TB): the diagnosis of latent tuberculosis infection (LTBI)","volume":"111","author":"Zellweger","year":"2020","journal-title":"Med. Lav."},{"key":"10.1016\/j.mimet.2026.107498_bb0200","doi-asserted-by":"crossref","first-page":"483","DOI":"10.2147\/IDR.S504632","article-title":"Advances in the diagnosis of latent tuberculosis infection","volume":"18","author":"Zhang","year":"2025","journal-title":"Infect. Drug Resist."}],"container-title":["Journal of Microbiological Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167701226001107?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167701226001107?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T12:55:19Z","timestamp":1784552119000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167701226001107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":40,"alternative-id":["S0167701226001107"],"URL":"https:\/\/doi.org\/10.1016\/j.mimet.2026.107498","relation":{},"ISSN":["0167-7012"],"issn-type":[{"value":"0167-7012","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An improved DiaRD MTB interferon-gamma release assay for the diagnosis of Mycobacterium Tuberculosis infections","name":"articletitle","label":"Article Title"},{"value":"Journal of Microbiological Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mimet.2026.107498","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107498"}}