{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:14:22Z","timestamp":1791976462336,"version":"4.4.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,19]],"date-time":"2021-06-19T00:00:00Z","timestamp":1624060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Mycology Case Reports"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.mmcr.2021.06.002","type":"journal-article","created":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T07:56:52Z","timestamp":1624521412000},"page":"18-20","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Hemophagocytic lymphohistiocytosis secondary to progressive disseminated histoplasmosis presenting as cellulitis"],"prefix":"10.1016","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9836-4835","authenticated-orcid":false,"given":"Alfredo G.","family":"Puing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3816-1542","authenticated-orcid":false,"given":"Shyam S.","family":"Raghavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria A.","family":"Aleshin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0709-2414","authenticated-orcid":false,"given":"Dora Y.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.mmcr.2021.06.002_bib1","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.27929","article-title":"Challenges in the diagnosis of hemophagocytic lymphohistiocytosis: recommendations from the North American Consortium for Histiocytosis (NACHO)","volume":"66","author":"Jordan","year":"2019","journal-title":"Pediatr. Blood Canc."},{"issue":"5","key":"10.1016\/j.mmcr.2021.06.002_bib2","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.hoc.2015.06.009","article-title":"Hemophagocytic lymphohistiocytosis in adults","volume":"29","author":"Campo","year":"2015","journal-title":"Hematol. Oncol. Clin. N. Am."},{"issue":"3","key":"10.1016\/j.mmcr.2021.06.002_bib3","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1097\/md.0b013e3180679130","article-title":"Systemic histoplasmosis: a 15-year retrospective institutional review of 111 patients","volume":"86","author":"Assi","year":"2007","journal-title":"Medicine (Baltim.)"},{"issue":"2","key":"10.1016\/j.mmcr.2021.06.002_bib4","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/pbc.21039","article-title":"HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis","volume":"48","author":"Henter","year":"2007","journal-title":"Pediatr. Blood Canc."},{"issue":"6","key":"10.1016\/j.mmcr.2021.06.002_bib5","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1086\/500405","article-title":"Hospitalizations for endemic mycoses: a population-based national study","volume":"42","author":"Chu","year":"2006","journal-title":"Clin. Infect. Dis."},{"issue":"8","key":"10.1016\/j.mmcr.2021.06.002_bib6","first-page":"785","article-title":"Epidemiology of endemic systemic fungal infections in Latin America","volume":"49","author":"Colombo","year":"2011","journal-title":"Med. Mycol."},{"issue":"6","key":"10.1016\/j.mmcr.2021.06.002_bib7","first-page":"569","article-title":"[A case of African histoplasmosis; with a mycological note on Histoplasma duboisii n.sp]","volume":"32","author":"Dubois","year":"1920","journal-title":"Ann. Soc. Belg. Med. Trop."},{"issue":"2","key":"10.1016\/j.mmcr.2021.06.002_bib8","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0966-842X(98)01431-0","article-title":"Macrophages in host defense against Histoplasma capsulatum","volume":"7","author":"Newman","year":"1999","journal-title":"Trends Microbiol."},{"issue":"3","key":"10.1016\/j.mmcr.2021.06.002_bib9","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s12275-016-6044-5","article-title":"Revisiting old friends: developments in understanding Histoplasma capsulatum pathogenesis","volume":"54","author":"Woods","year":"2016","journal-title":"J. Microbiol."},{"issue":"5","key":"10.1016\/j.mmcr.2021.06.002_bib10","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/00005792-198309000-00001","article-title":"Clinical and laboratory features of disseminated histoplasmosis during two large urban outbreaks","volume":"62","author":"Sathapatayavongs","year":"1983","journal-title":"Medicine (Baltim.)"},{"issue":"1","key":"10.1016\/j.mmcr.2021.06.002_bib11","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1590\/abd1806-4841.20197636","article-title":"Histoplasma panniculitis in a patient with systemic lupus erythematosus","volume":"94","author":"Flores-Bozo","year":"2019","journal-title":"An. Bras. Dermatol."},{"issue":"12","key":"10.1016\/j.mmcr.2021.06.002_bib12","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/S1473-3099(07)70290-6","article-title":"Infections associated with haemophagocytic syndrome","volume":"7","author":"Rouphael","year":"2007","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.mmcr.2021.06.002_bib13","doi-asserted-by":"crossref","first-page":"7107326","DOI":"10.1155\/2019\/7107326","article-title":"Histoplasmosis-associated hemophagocytic lymphohistiocytosis: a review of the literature","volume":"2019","author":"Jabr","year":"2019","journal-title":"Can. J. Infect Dis. Med. Microbiol."},{"issue":"6","key":"10.1016\/j.mmcr.2021.06.002_bib14","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s12185-017-2308-z","article-title":"Hemophagocytic lymphohistiocytosis secondary to disseminated histoplasmosis in systemic lupus erythematosus","volume":"106","author":"Souto Filho Jtd","year":"2017","journal-title":"Int. J. Hematol."},{"issue":"1","key":"10.1016\/j.mmcr.2021.06.002_bib15","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/01.idc.0000227711.03883.8d","article-title":"Reactive hemophagocytosis in a patient with systemic lupus erythematosus and disseminated histoplamosis","volume":"15","author":"Shibata","year":"2007","journal-title":"Infect. Dis. Clin. Pract."},{"issue":"5","key":"10.1016\/j.mmcr.2021.06.002_bib16","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1002\/ccr3.2079","article-title":"Progressive and disseminated histoplasma infection and hemophagocytic lymphohistiocytosis in an immunocompetent adult","volume":"7","author":"Dousa","year":"2019","journal-title":"Clin. Case Rep."},{"issue":"23","key":"10.1016\/j.mmcr.2021.06.002_bib17","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1182\/blood.2018894618","article-title":"Recommendations for the management of hemophagocytic lymphohistiocytosis in adults","volume":"133","author":"La Ros\u00e9e","year":"2019","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.mmcr.2021.06.002_bib18","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1164\/rccm.2008-740ST","article-title":"An official American Thoracic Society statement: treatment of fungal infections in adult pulmonary and critical care patients","volume":"183","author":"Limper","year":"2011","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"7","key":"10.1016\/j.mmcr.2021.06.002_bib19","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1086\/521259","article-title":"Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America","volume":"45","author":"Wheat","year":"2007","journal-title":"Clin. Infect. Dis."},{"issue":"2","key":"10.1016\/j.mmcr.2021.06.002_bib20","doi-asserted-by":"crossref","first-page":"ofv055","DOI":"10.1093\/ofid\/ofv055","article-title":"Histoplasmosis-induced hemophagocytic syndrome: a case series and review of the literature","volume":"2","author":"Townsend","year":"2015","journal-title":"Open Forum Infect. Dis."}],"container-title":["Medical Mycology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211753921000373?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211753921000373?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T18:02:44Z","timestamp":1761933764000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211753921000373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":20,"alternative-id":["S2211753921000373"],"URL":"https:\/\/doi.org\/10.1016\/j.mmcr.2021.06.002","relation":{},"ISSN":["2211-7539"],"issn-type":[{"value":"2211-7539","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hemophagocytic lymphohistiocytosis secondary to progressive disseminated histoplasmosis presenting as cellulitis","name":"articletitle","label":"Article Title"},{"value":"Medical Mycology Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mmcr.2021.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier B.V. on behalf of International Society for Human and Animal Mycology.","name":"copyright","label":"Copyright"}]}}