{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:57:32Z","timestamp":1793833052708,"version":"4.6.1"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Medical Mycology Case Reports"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.mmcr.2025.100750","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T01:37:35Z","timestamp":1763084255000},"page":"100750","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Successful treatment of a resistant invasive disseminated Fusarium infection in an immunocompetent patient"],"prefix":"10.1016","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3897-6282","authenticated-orcid":false,"given":"Frantzeska","family":"Frantzeskaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolas","family":"Stratopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5963-4987","authenticated-orcid":false,"given":"Sandra","family":"Elise van der Griend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Renieris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7489-7776","authenticated-orcid":false,"given":"Kostantinos","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iraklis","family":"Tsagkaris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.mmcr.2025.100750_bib1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1046\/j.1365-2672.1998.00388.x","article-title":"Bacterial-fungal biofilms in flowing water photo-processing tanks","volume":"84","author":"Elvers","year":"1998","journal-title":"J. Appl. Microbiol."},{"issue":"2","key":"10.1016\/j.mmcr.2025.100750_bib2","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3201\/eid3002.231221","article-title":"Multicenter retrospective study of invasive fusariosis in intensive care units, France","volume":"30","author":"Demonchy","year":"2024","journal-title":"Emerg. Infect. Dis."},{"issue":"4","key":"10.1016\/j.mmcr.2025.100750_bib3","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1128\/CMR.00014-07","article-title":"Fusarium infections in immunocompromised patients","volume":"20","author":"Nucci","year":"2007","journal-title":"Clin. Microbiol. Rev."},{"issue":"1","key":"10.1016\/j.mmcr.2025.100750_bib4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3201\/eid2701.190782","article-title":"Invasive fusariosis in nonneutropenic patients, Spain, 2000-2015","volume":"27","author":"P\u00e9rez-Nadales","year":"2021","journal-title":"Emerg. Infect. Dis."},{"issue":"4","key":"10.1016\/j.mmcr.2025.100750_bib5","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/jac\/dkn022","article-title":"Antifungal susceptibility profile of clinical Fusarium spp. isolates identified by molecular methods","volume":"61","author":"Alastruey-Izquierdo","year":"2008","journal-title":"J. Antimicrob. Chemother."},{"issue":"7","key":"10.1016\/j.mmcr.2025.100750_bib6","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1128\/AAC.00272-08","article-title":"Species distribution and in vitro antifungal susceptibility patterns of 75 clinical isolates of Fusarium spp. from northern Italy","volume":"52","author":"Tortorano","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"issue":"3","key":"10.1016\/j.mmcr.2025.100750_bib7","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01735-19","article-title":"Fosmanogepix (APX001) is effective in the treatment of immunocompromised mice infected with invasive pulmonary scedosporiosis or disseminated fusariosis","volume":"64","author":"Alkhazraji","year":"2020","journal-title":"Antimicrob. Agents Chemother."},{"issue":"4","key":"10.1016\/j.mmcr.2025.100750_bib8","article-title":"Fosmanogepix: the novel anti-fungal agent's comprehensive review of in vitro, in vivo, and current insights from advancing clinical trials","volume":"16","author":"Almajid","year":"2024","journal-title":"Cureus"},{"issue":"4","key":"10.1016\/j.mmcr.2025.100750_bib9","article-title":"Fosmanogepix: a review of the first-in-class broad spectrum agent for the treatment of invasive fungal infections","volume":"6","author":"Shaw","year":"2020","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.mmcr.2025.100750_bib10","doi-asserted-by":"crossref","first-page":"644","DOI":"10.3390\/jof11090644","article-title":"Rare mould fungaemia at a teritary academic hospital in Athens, Greece: a 15 year survey and literature review","volume":"11","author":"Siopi","year":"2025","journal-title":"J. Fungi"},{"key":"10.1016\/j.mmcr.2025.100750_bib11","series-title":"Method for the Determination of Broth Dilution Minimum Inhibitory Concentrations of Antifungal Agents for Conidia Forming Moulds","author":"Guinea","year":"2022"},{"issue":"3","key":"10.1016\/j.mmcr.2025.100750_bib12","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1439-0507.2006.01346.x","article-title":"Treating disseminated fusariosis: amphotericin B, voriconazole or both?","volume":"50","author":"Ho","year":"2007","journal-title":"Mycoses"},{"issue":"10","key":"10.1016\/j.mmcr.2025.100750_bib13","doi-asserted-by":"crossref","first-page":"4898","DOI":"10.1128\/JCM.41.10.4898-4900.2003","article-title":"Successful outcome of disseminated fusarium infection with skin localization treated with voriconazole and amphotericin B-lipid complex in a patient with acute leukemia","volume":"41","author":"Durand-Joly","year":"2003","journal-title":"J. Clin. Microbiol."},{"issue":"2","key":"10.1016\/j.mmcr.2025.100750_bib14","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1086\/589305","article-title":"Caspofungin-mediated \u03b2-Glucan unmasking and enhancement of human polymorphonuclear neutrophil activity against aspergillus and non-aspergillus hyphae","volume":"198","author":"Lamaris","year":"2008","journal-title":"J. Infect. Dis."},{"issue":"6","key":"10.1016\/j.mmcr.2025.100750_bib15","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1056\/NEJMoa2308192","article-title":"Neurovascular complications of iatrogenic Fusarium solani meningitis","volume":"390","author":"Strong","year":"2024","journal-title":"N. Engl. J. Med."},{"issue":"6","key":"10.1016\/j.mmcr.2025.100750_bib16","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1093\/cid\/ciad309","article-title":"Fosmanogepix therapy of disseminated fusarium infection","volume":"77","author":"Winston","year":"2023","journal-title":"Clin. Infect. Dis."},{"issue":"6","key":"10.1016\/j.mmcr.2025.100750_bib17","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofad285","article-title":"Successful use of fosmanogepix for treatment of rare highly resistant cutaneous fusariosis in a pediatric patient with STAT3 hyper-immunoglobulin E syndrome and end-stage kidney disease","volume":"10","author":"Goggin","year":"2023","journal-title":"Open Forum Infect. Dis."},{"issue":"4","key":"10.1016\/j.mmcr.2025.100750_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.healun.2024.02.1437","article-title":"Multi-drug resistant fusariosis treated with fosmanogepix in a lung transplant patient","volume":"43","author":"Wu","year":"2024","journal-title":"J. Heart Lung Transplant."}],"container-title":["Medical Mycology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211753925000594?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211753925000594?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T13:08:20Z","timestamp":1769173700000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211753925000594"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":18,"alternative-id":["S2211753925000594"],"URL":"https:\/\/doi.org\/10.1016\/j.mmcr.2025.100750","relation":{},"ISSN":["2211-7539"],"issn-type":[{"value":"2211-7539","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Successful treatment of a resistant invasive disseminated Fusarium infection in an immunocompetent patient","name":"articletitle","label":"Article Title"},{"value":"Medical Mycology Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mmcr.2025.100750","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V. on behalf of International Society for Human and Animal Mycology.","name":"copyright","label":"Copyright"}],"article-number":"100750"}}