{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T20:52:43Z","timestamp":1789937563300,"version":"4.0.1"},"reference-count":23,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular and Biochemical Parasitology"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.molbiopara.2011.08.003","type":"journal-article","created":{"date-parts":[[2011,8,29]],"date-time":"2011-08-29T15:01:50Z","timestamp":1314630110000},"page":"115-119","source":"Crossref","is-referenced-by-count":12,"title":["TsAg5, a Taenia solium cysticercus protein with a marginal trypsin-like activity in the diagnosis of human neurocysticercosis"],"prefix":"10.1016","volume":"180","author":[{"given":"Analiz","family":"Rueda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Sifuentes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert H.","family":"Gilman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s H.","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruby","family":"Pi\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Chile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebasti\u00e1n","family":"Carrasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Larson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Mayta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Ver\u00e1stegui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Guti\u00e9rrez-Correa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9ctor H.","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Sheen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirko","family":"Zimic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molbiopara.2011.08.003_bib0005","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0140-6736(93)90064-N","article-title":"Cysticercosis as a major cause of epilepsy in Peru. The Cysticercosis Working Group in Peru (CWG)","volume":"341","author":"Garcia","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0010","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0014-4894(89)90016-7","article-title":"Parasite proteases","volume":"68","author":"McKerrow","year":"1989","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0015","doi-asserted-by":"crossref","first-page":"7","DOI":"10.2307\/3284107","article-title":"Taenia saginata oncosphere excretory\/secretory peptidases","volume":"82","author":"White","year":"1996","journal-title":"J Parasitol"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0020","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1645\/GE-959R.1","article-title":"Comparison of the peptidase activity in the oncosphere excretory\/secretory products of Taenia solium and Taenia saginata","volume":"93","author":"Zimic","year":"2007","journal-title":"J Parasitol"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0025","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0166-6851(89)90149-7","article-title":"Subunit composition and specificity of the major cyst fluid antigens of Echinococcus granulosus","volume":"37","author":"Lightowlers","year":"1989","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0030","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1042\/bj20021402","article-title":"Echinococcus granulosus antigen 5 is closely related to proteases of the trypsin family","volume":"369","author":"Lorenzo","year":"2003","journal-title":"Biochem J"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0035","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0378-1119(01)00819-8","article-title":"ORF-FINDER: a vector for high-throughput gene identification","volume":"282","author":"Rombel","year":"2002","journal-title":"Gene"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0040","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.jmb.2004.03.016","article-title":"A combined transmembrane topology and signal peptide prediction method","volume":"338","author":"Kall","year":"2004","journal-title":"J Mol Biol"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0045","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1110\/ps.0303703","article-title":"Prediction of lipoprotein signal peptides in Gram-negative bacteria","volume":"12","author":"Juncker","year":"2003","journal-title":"Protein Sci"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0050","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1515\/BC.1999.138","article-title":"Fluorometric microassays for the determination of cathepsin L and cathepsin S activities in tissue extracts","volume":"380","author":"Werle","year":"1999","journal-title":"Biol Chem"},{"issue":"6","key":"10.1016\/j.molbiopara.2011.08.003_bib0055","doi-asserted-by":"crossref","first-page":"964","DOI":"10.4269\/ajtmh.2009.80.964","article-title":"Utility of a protein fraction with cathepsin-L like activity purified from cysticercus fluid of Taenia solium in the diagnosis of human cysticercosis","volume":"80","author":"Zimic","year":"2009","journal-title":"Am J Trop Med Hyg."},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0060","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1128\/AAC.00761-10","article-title":"Sensitive in vitro system to assess morphological and biochemical effects of praziquantel and albendazole on Taenia solium cysts","volume":"55","author":"Mahanty","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0065","doi-asserted-by":"crossref","first-page":"964","DOI":"10.4269\/ajtmh.2009.80.964","article-title":"Utility of a protein fraction with cathepsin L-Like activity purified from cysticercus fluid of Taenia solium in the diagnosis of human cysticercosis","volume":"80","author":"Zimic","year":"2009","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0070","doi-asserted-by":"crossref","first-page":"438","DOI":"10.4269\/ajtmh.2003.69.438","article-title":"Prevalence of antibodies to unique Taenia solium oncosphere antigens in taeniasis and human and porcine cysticercosis","volume":"69","author":"Verastegui","year":"2003","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0075","doi-asserted-by":"crossref","first-page":"5158","DOI":"10.1128\/IAI.01175-06","article-title":"Taenia solium oncosphere adhesion to intestinal epithelial and Chinese hamster ovary cells in vitro","volume":"75","author":"Verastegui","year":"2007","journal-title":"Infect Immun"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0080","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.pt.2009.12.008","article-title":"Immunodiagnosis of Taenia solium taeniosis\/cysticercosis","volume":"26","author":"Deckers","year":"2010","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0085","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1086\/597757","article-title":"Detection of Taenia solium antigens and anti-T. solium antibodies in paired serum and cerebrospinal fluid samples from patients with intraparenchymal or extraparenchymal neurocysticercosis","volume":"199","author":"Rodriguez","year":"2009","journal-title":"J Infect Dis"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0090","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1017\/S0031182005008309","article-title":"The immunogenicity of Echinococcus granulosus antigen 5 is determined by its post-translational modifications","volume":"131","author":"Lorenzo","year":"2005","journal-title":"Parasitology"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0095","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1590\/S1726-46342010000400015","article-title":"Neurocysticercosis diagnosis and management in Peru","volume":"27","author":"Saavedra","year":"2010","journal-title":"Rev Peru Med Exp Salud Publica"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0100","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1365-3024.1987.tb00505.x","article-title":"Cyst fluid and surface associated glycoprotein antigens of Taenia sp. metacestodes","volume":"9","author":"Parkhouse","year":"1987","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0105","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1590\/S0036-46651994000400005","article-title":"The diagnostic importance of species specific and cross-reactive components of Taenia solium, Echinococcus granulosus, and Hymenolepis nana","volume":"36","author":"Montenegro","year":"1994","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1079\/JOH2004266","article-title":"Parasitic zoonoses in Papua New Guinea","volume":"79","author":"Owen","year":"2005","journal-title":"J Helminthol"},{"key":"10.1016\/j.molbiopara.2011.08.003_bib0115","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.trstmh.2006.04.004","article-title":"Hymenolepis nana infection: symptoms and response to nitazoxanide in field conditions","volume":"101","author":"Chero","year":"2007","journal-title":"Trans R Soc Trop Med Hyg"}],"container-title":["Molecular and Biochemical Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166685111001903?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0166685111001903?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T11:20:34Z","timestamp":1560511234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0166685111001903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S0166685111001903"],"URL":"https:\/\/doi.org\/10.1016\/j.molbiopara.2011.08.003","relation":{},"ISSN":["0166-6851"],"issn-type":[{"value":"0166-6851","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12]]}}}