{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T05:35:57Z","timestamp":1791610557697,"version":"4.3.4"},"reference-count":60,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":3060,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Cell"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1016\/j.molcel.2005.02.010","type":"journal-article","created":{"date-parts":[[2005,3,11]],"date-time":"2005-03-11T12:32:50Z","timestamp":1110544370000},"page":"683-694","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":189,"title":["Mediator Requirement for Both Recruitment and Postrecruitment Steps in Transcription Initiation"],"prefix":"10.1016","volume":"17","author":[{"given":"Gang","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Balamotis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennitte L.","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Handa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnold J.","family":"Berk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molcel.2005.02.010_bib1","doi-asserted-by":"crossref","first-page":"6354","DOI":"10.1128\/MCB.22.18.6354-6362.2002","article-title":"Mechanism of rapid transcriptional induction of tumor necrosis factor alpha-responsive genes by NF-kappaB","volume":"22","author":"Ainbinder","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib2","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1128\/MCB.24.6.2444-2454.2004","article-title":"Elongation inhibition by DRB sensitivity-inducing factor is regulated by the A20 promoter via a novel negative element and NF-kappaB","volume":"24","author":"Ainbinder","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib3","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1101\/gad.844200","article-title":"High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation","volume":"14","author":"Andrulis","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.02.010_bib4","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev.biochem.71.110601.135400","article-title":"ATP-dependent nucleosome remodeling","volume":"71","author":"Becker","year":"2002","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.molcel.2005.02.010_bib5","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.molcel.2004.05.011","article-title":"A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II","volume":"14","author":"Bourbon","year":"2004","journal-title":"Mol. Cell"},{"key":"10.1016\/j.molcel.2005.02.010_bib6","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/20466","article-title":"Mammalian Srb\/Mediator complex is targeted by adenovirus E1A protein","volume":"399","author":"Boyer","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2005.02.010_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gene.2003.09.028","article-title":"Ets ternary complex transcription factors","volume":"324","author":"Buchwalter","year":"2004","journal-title":"Gene"},{"key":"10.1016\/j.molcel.2005.02.010_bib8","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1006\/jmbi.1999.3161","article-title":"Transcription activation by catabolite activator protein (CAP)","volume":"293","author":"Busby","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib9","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/S0021-9258(19)75926-2","article-title":"Transcription initiation by RNA polymerase II in vitro. Properties of preinitiation, initiation, and elongation complexes","volume":"262","author":"Cai","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molcel.2005.02.010_bib10","doi-asserted-by":"crossref","first-page":"12003","DOI":"10.1073\/pnas.2035253100","article-title":"Activation domain-mediator interactions promote transcription preinitiation complex assembly on promoter DNA","volume":"100","author":"Cantin","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.molcel.2005.02.010_bib11","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1101\/gad.935901","article-title":"Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain","volume":"15","author":"Cho","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.02.010_bib12","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1101\/gad.1071803","article-title":"Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation","volume":"17","author":"Corey","year":"2003","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.02.010_bib13","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/S0955-0674(03)00013-9","article-title":"Histone and chromatin cross-talk","volume":"15","author":"Fischle","year":"2003","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib14","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1126\/science.1059495","article-title":"Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution","volume":"292","author":"Gnatt","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.02.010_bib15","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0092-8674(94)90242-9","article-title":"Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II","volume":"77","author":"Goodrich","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.02.010_bib16","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/340068a0","article-title":"Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction","volume":"340","author":"Herrera","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2005.02.010_bib17","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0092-8674(00)81641-4","article-title":"Dissecting the regulatory circuitry of a eukaryotic genome","volume":"95","author":"Holstege","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.02.010_bib18","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1126\/science.1074200","article-title":"Molecular biology. Chromatin higher order folding\u2013wrapping up transcription","volume":"297","author":"Horn","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.02.010_bib19","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1006\/bbrc.1996.1740","article-title":"MAP kinase-dependent transcriptional coactivation by Elk-1 and its cofactor CBP","volume":"228","author":"Janknecht","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.molcel.2005.02.010_bib20","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1101\/gad.831900","article-title":"Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster","volume":"14","author":"Kaplan","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.02.010_bib21","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/0092-8674(94)90221-6","article-title":"A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II","volume":"77","author":"Kim","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.02.010_bib22","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/20302","article-title":"A shared but complex bridge","volume":"399","author":"Kingston","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2005.02.010_bib23","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1101\/gad.824700","article-title":"Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription","volume":"14","author":"Komarnitsky","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.02.010_bib24","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/21239","article-title":"Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme","volume":"399","author":"Kuras","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2005.02.010_bib25","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/ng1400","article-title":"Evidence for nucleosome depletion at active regulatory regions genome-wide","volume":"36","author":"Lee","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.molcel.2005.02.010_bib26","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1146\/annurev.genet.34.1.77","article-title":"Transcription of eukaryotic protein-coding genes","volume":"34","author":"Lee","year":"2000","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/j.molcel.2005.02.010_bib27","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/(SICI)1097-0177(199805)212:1<38::AID-AJA4>3.0.CO;2-3","article-title":"Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein","volume":"212","author":"LeGouy","year":"1998","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.molcel.2005.02.010_bib28","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/emboj\/cdg028","article-title":"MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300","volume":"22","author":"Li","year":"2003","journal-title":"EMBO J."},{"key":"10.1016\/j.molcel.2005.02.010_bib29","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/21232","article-title":"Enhancement of TBP binding by activators and general transcription factors","volume":"399","author":"Li","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2005.02.010_bib30","doi-asserted-by":"crossref","first-page":"7357","DOI":"10.1073\/pnas.0401866101","article-title":"Distinct localization of histone H3 acetylation and H3\u2013K4 methylation to the transcription start sites in the human genome","volume":"101","author":"Liang","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.molcel.2005.02.010_bib31","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1101\/sqb.1998.63.347","article-title":"Promoter-associated pausing in promoter architecture and postinitiation transcriptional regulation","volume":"63","author":"Lis","year":"1998","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib32","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S1097-2765(05)00007-9","article-title":"Mediator-nucleosome interaction","volume":"6","author":"Lorch","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1016\/j.molcel.2005.02.010_bib33","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0968-0004(00)01596-6","article-title":"Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells","volume":"25","author":"Malik","year":"2000","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.molcel.2005.02.010_bib34","doi-asserted-by":"crossref","first-page":"5626","DOI":"10.1128\/MCB.22.15.5626-5637.2002","article-title":"TRAP\/SMCC\/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4","volume":"22","author":"Malik","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib35","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1146\/annurev.biochem.69.1.729","article-title":"Mediator of transcriptional regulation","volume":"69","author":"Myers","year":"2000","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.molcel.2005.02.010_bib36","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1101\/gad.987602","article-title":"Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation","volume":"16","author":"Naar","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.02.010_bib37","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S1097-2765(03)00092-3","article-title":"Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity","volume":"11","author":"Ng","year":"2003","journal-title":"Mol. Cell"},{"key":"10.1016\/j.molcel.2005.02.010_bib38","doi-asserted-by":"crossref","first-page":"5213","DOI":"10.1074\/jbc.M007824200","article-title":"Induction-independent recruitment of CREB-binding protein to the c-fos serum response element through interactions between the bromodomain and Elk-1","volume":"276","author":"Nissen","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molcel.2005.02.010_bib39","doi-asserted-by":"crossref","first-page":"4689","DOI":"10.1074\/jbc.273.8.4689","article-title":"Growth-related changes in phosphorylation of yeast RNA polymerase II","volume":"273","author":"Patturajan","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molcel.2005.02.010_bib40","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.cell.2004.07.016","article-title":"MAP kinase-mediated stress relief that precedes and regulates the timing of transcriptional induction","volume":"118","author":"Proft","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.02.010_bib41","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1101\/gad.13.1.49","article-title":"Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB","volume":"13","author":"Ranish","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.02.010_bib42","doi-asserted-by":"crossref","first-page":"42601","DOI":"10.1074\/jbc.M104967200","article-title":"A highly purified RNA polymerase II elongation control system","volume":"276","author":"Renner","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molcel.2005.02.010_bib43","doi-asserted-by":"crossref","first-page":"6675","DOI":"10.1016\/S0021-9258(19)42207-2","article-title":"Ribonucleic acid chain elongation by Escherichia coli ribonucleic acid polymerase. I. Isolation of ternary complexes and the kinetics of elongation","volume":"249","author":"Rhodes","year":"1974","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molcel.2005.02.010_bib44","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/0022-2836(84)90174-8","article-title":"Kinetics and mechanism of the interaction of Escherichia coli RNA polymerase with the lambda PR promoter","volume":"176","author":"Roe","year":"1984","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib45","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1101\/sqb.1998.63.201","article-title":"Role of general and gene-specific cofactors in the regulation of eukaryotic transcription","volume":"63","author":"Roeder","year":"1998","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib46","doi-asserted-by":"crossref","first-page":"6422","DOI":"10.1073\/pnas.1030497100","article-title":"TRAP230\/ARC240 and TRAP240\/ARC250 Mediator subunits are functionally conserved through evolution","volume":"100","author":"Samuelsen","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.molcel.2005.02.010_bib47","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/nature01080","article-title":"Active genes are tri-methylated at K4 of histone H3","volume":"419","author":"Santos-Rosa","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2005.02.010_bib48","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.molcel.2004.05.006","article-title":"A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology","volume":"14","author":"Sato","year":"2004","journal-title":"Mol. Cell"},{"key":"10.1016\/j.molcel.2005.02.010_bib49","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/S1357-2725(03)00031-1","article-title":"Ternary complex factors: prime nuclear targets for mitogen-activated protein kinases","volume":"35","author":"Shaw","year":"2003","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib50","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1101\/gad.999002","article-title":"CDK-9\/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo","volume":"16","author":"Shim","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.02.010_bib51","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1126\/science.1068943","article-title":"Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit","volume":"296","author":"Stevens","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.02.010_bib52","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1126\/science.1065249","article-title":"Structure, function, and activator-induced conformations of the CRSP coactivator","volume":"295","author":"Taatjes","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.02.010_bib53","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/nrm1369","article-title":"Regulatory diversity among metazoan co-activator complexes","volume":"5","author":"Taatjes","year":"2004","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib54","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/jcp.10178","article-title":"Regulation of life and death by the zinc finger transcription factor Egr-1","volume":"193","author":"Thiel","year":"2002","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.molcel.2005.02.010_bib55","doi-asserted-by":"crossref","first-page":"24392","DOI":"10.1074\/jbc.270.41.24392","article-title":"Abortive cycling and the release of polymerase for elongation at the sigma 54-dependent glnAp2 promoter","volume":"270","author":"Tintut","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molcel.2005.02.010_bib56","doi-asserted-by":"crossref","first-page":"9186","DOI":"10.1128\/JVI.76.18.9186-9193.2002","article-title":"In vivo association of adenovirus large E1A protein with the human mediator complex in adenovirus-infected and -transformed cells","volume":"76","author":"Wang","year":"2002","journal-title":"J. Virol."},{"key":"10.1016\/j.molcel.2005.02.010_bib57","doi-asserted-by":"crossref","first-page":"4604","DOI":"10.1128\/MCB.21.14.4604-4613.2001","article-title":"Characterization of mediator complexes from HeLa cell nuclear extract","volume":"21","author":"Wang","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.02.010_bib58","first-page":"143","article-title":"The SWI\/SNF family of ATP-dependent chromatin remodelers: similar mechanisms for diverse functions","volume":"274","author":"Wang","year":"2003","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.molcel.2005.02.010_bib59","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1101\/gad.1091403","article-title":"NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila","volume":"17","author":"Wu","year":"2003","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.02.010_bib60","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0092-8674(00)80713-8","article-title":"NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation","volume":"97","author":"Yamaguchi","year":"1999","journal-title":"Cell"}],"container-title":["Molecular Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097276505010877?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097276505010877?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:03:47Z","timestamp":1761091427000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1097276505010877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":60,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["S1097276505010877"],"URL":"https:\/\/doi.org\/10.1016\/j.molcel.2005.02.010","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1024450.287908","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1024450.288835","asserted-by":"object"}]},"ISSN":["1097-2765"],"issn-type":[{"value":"1097-2765","type":"print"}],"subject":[],"published":{"date-parts":[[2005,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mediator Requirement for Both Recruitment and Postrecruitment Steps in Transcription Initiation","name":"articletitle","label":"Article Title"},{"value":"Molecular Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molcel.2005.02.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}