{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:28:43Z","timestamp":1791422923159,"version":"4.3.3"},"reference-count":65,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":2912,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Cell"],"published-print":{"date-parts":[[2005,9]]},"DOI":"10.1016\/j.molcel.2005.07.021","type":"journal-article","created":{"date-parts":[[2005,9,6]],"date-time":"2005-09-06T18:05:14Z","timestamp":1126029914000},"page":"667-678","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":304,"title":["DNA Binding Selectivity of MeCP2 Due to a Requirement for A\/T Sequences Adjacent to Methyl-CpG"],"prefix":"10.1016","volume":"19","author":[{"given":"Robert J.","family":"Klose","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shireen A.","family":"Sarraf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Schmiedeberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne M.","family":"McDermott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Stancheva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian P.","family":"Bird","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molcel.2005.07.021_bib1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/13810","article-title":"Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2","volume":"23","author":"Amir","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.molcel.2005.07.021_bib2","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/0092-8674(89)90431-5","article-title":"Specific protection of methylated CpGs in mammalian nuclei","volume":"58","author":"Antequera","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib3","doi-asserted-by":"crossref","first-page":"4413","DOI":"10.1093\/nar\/26.19.4413","article-title":"AT-hook motifs identified in a wide variety of DNA-binding proteins","volume":"26","author":"Aravind","year":"1998","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.molcel.2005.07.021_bib4","doi-asserted-by":"crossref","first-page":"6335","DOI":"10.1093\/emboj\/cdg604","article-title":"Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer","volume":"22","author":"Ballestar","year":"2003","journal-title":"EMBO J."},{"key":"10.1016\/j.molcel.2005.07.021_bib5","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1101\/gad.947102","article-title":"DNA methylation patterns and epigenetic memory","volume":"16","author":"Bird","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.07.021_bib6","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/0092-8674(91)90267-3","article-title":"DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein","volume":"64","author":"Boyes","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib7","doi-asserted-by":"crossref","first-page":"4108","DOI":"10.1021\/bi00012a029","article-title":"Nuclear matrix protein ARBP recognizes a novel DNA sequence motif with high affinity","volume":"34","author":"Buhrmester","year":"1995","journal-title":"Biochemistry"},{"key":"10.1016\/j.molcel.2005.07.021_bib8","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/85906","article-title":"Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice","volume":"27","author":"Chen","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/j.molcel.2005.07.021_bib9","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1126\/science.1086446","article-title":"Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2","volume":"302","author":"Chen","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.07.021_bib10","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1126\/science.1078572","article-title":"Maintenance of stable heterochromatin domains by dynamic HP1 binding","volume":"299","author":"Cheutin","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.07.021_bib11","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1128\/MCB.24.8.3157-3167.2004","article-title":"In vivo dynamics of Swi6 in yeast: evidence for a stochastic model of heterochromatin","volume":"24","author":"Cheutin","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib12","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1126\/science.1083557","article-title":"Chromosomal instability and tumors promoted by DNA hypomethylation","volume":"300","author":"Eden","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.07.021_bib13","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1128\/MCB.22.6.1844-1857.2002","article-title":"Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation","volume":"22","author":"El-Osta","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib14","first-page":"827","article-title":"The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes","volume":"15","author":"Feng","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.07.021_bib15","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1093\/nar\/gkg249","article-title":"The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties","volume":"31","author":"Fraga","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.molcel.2005.07.021_bib16","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1074\/jbc.M007224200","article-title":"DNA recognition by the methyl-CpG binding domain of MeCP2","volume":"276","author":"Free","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molcel.2005.07.021_bib17","doi-asserted-by":"crossref","first-page":"8302","DOI":"10.1128\/MCB.22.23.8302-8319.2002","article-title":"Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure","volume":"22","author":"Ghoshal","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib18","doi-asserted-by":"crossref","first-page":"5426","DOI":"10.1128\/MCB.21.16.5426-5436.2001","article-title":"DNA methylation is linked to deacetylation of histone H3, but not H4, on the imprinted genes Snrpn and U2af1-rs1","volume":"21","author":"Gregory","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib19","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/85899","article-title":"A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome","volume":"27","author":"Guy","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/j.molcel.2005.07.021_bib20","doi-asserted-by":"crossref","first-page":"3459","DOI":"10.1242\/jcs.01160","article-title":"Dynamic interaction of HMGA1a proteins with chromatin","volume":"117","author":"Harrer","year":"2004","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.molcel.2005.07.021_bib21","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1006\/jmbi.1996.0006","article-title":"In vitro evolution of the DNA binding sites of Escherichia coli methionine repressor, MetJ","volume":"255","author":"He","year":"1996","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib22","doi-asserted-by":"crossref","first-page":"6538","DOI":"10.1128\/MCB.18.11.6538","article-title":"Identification and characterization of a family of mammalian methyl-CpG binding proteins","volume":"18","author":"Hendrich","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib23","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0168-9525(03)00080-5","article-title":"The methyl-CpG binding domain and the evolving role of DNA methylation in animals","volume":"19","author":"Hendrich","year":"2003","journal-title":"Trends Genet."},{"key":"10.1016\/j.molcel.2005.07.021_bib24","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/45843","article-title":"The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites","volume":"401","author":"Hendrich","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2005.07.021_bib25","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1101\/gad.194101","article-title":"Closely related proteins Mbd2 and Mbd3 play distinctive but interacting roles in mouse development","volume":"15","author":"Hendrich","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.07.021_bib26","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/ng1491","article-title":"Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome","volume":"37","author":"Horike","year":"2005","journal-title":"Nat. Genet."},{"key":"10.1016\/j.molcel.2005.07.021_bib27","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/nar\/9.3.683","article-title":"Nucleotide sequence of mouse satellite DNA","volume":"9","author":"H\u00f6rz","year":"1981","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.molcel.2005.07.021_bib28","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/83730","article-title":"Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation","volume":"27","author":"Jackson-Grusby","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/j.molcel.2005.07.021_bib29","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/561","article-title":"Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription","volume":"19","author":"Jones","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.molcel.2005.07.021_bib30","doi-asserted-by":"crossref","first-page":"3387","DOI":"10.1128\/MCB.24.8.3387-3395.2004","article-title":"Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains","volume":"24","author":"Jorgensen","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib31","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1126\/science.1091762","article-title":"Molecular biology. MeCP2 repression goes nonglobal","volume":"302","author":"Klose","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.07.021_bib32","doi-asserted-by":"crossref","first-page":"46490","DOI":"10.1074\/jbc.M408284200","article-title":"MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex","volume":"279","author":"Klose","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molcel.2005.07.021_bib33","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF00996358","article-title":"All you wanted to know about SELEX","volume":"20","author":"Klug","year":"1994","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.molcel.2005.07.021_bib34","doi-asserted-by":"crossref","first-page":"5011","DOI":"10.1021\/bi0359271","article-title":"DNA binding of methyl-CpG-binding protein MeCP2 in human MCF7 cells","volume":"43","author":"Koch","year":"2004","journal-title":"Biochemistry"},{"key":"10.1016\/j.molcel.2005.07.021_bib35","doi-asserted-by":"crossref","first-page":"4388","DOI":"10.1128\/MCB.25.11.4388-4396.2005","article-title":"The thymine DNA glycosylase MBD4 represses transcription and is associated with methylated p16INK4a and hMLH1 genes","volume":"25","author":"Kondo","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib36","doi-asserted-by":"crossref","first-page":"3039","DOI":"10.1128\/MCB.19.4.3039","article-title":"The SKN-1 amino-terminal arm is a DNA specificity segment","volume":"19","author":"Kophengnavong","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib37","doi-asserted-by":"crossref","first-page":"R221","DOI":"10.1093\/hmg\/ddg286","article-title":"DNA methylation and Rett syndrome","volume":"12 Spec No 2","author":"Kriaucionis","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.molcel.2005.07.021_bib38","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1038\/35048603","article-title":"Rapid exchange of histone H1.1 on chromatin in living human cells","volume":"408","author":"Lever","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2005.07.021_bib39","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/0092-8674(92)90610-O","article-title":"Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA","volume":"69","author":"Lewis","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib40","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/0092-8674(92)90611-F","article-title":"Targeted mutation of the DNA methyltransferase gene results in embryonic lethality","volume":"69","author":"Li","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib41","doi-asserted-by":"crossref","first-page":"7913","DOI":"10.1128\/MCB.21.23.7913-7922.2001","article-title":"Methylation-mediated proviral silencing is associated with MeCP2 recruitment and localized histone H3 deacetylation","volume":"21","author":"Lorincz","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib42","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0014-5793(81)80746-6","article-title":"Consensus sequence of mouse satellite DNA indicates it is derived from tandem 116 basepair repeats","volume":"129","author":"Manuelidis","year":"1981","journal-title":"FEBS Lett."},{"key":"10.1016\/j.molcel.2005.07.021_bib43","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1126\/science.1090842","article-title":"DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation","volume":"302","author":"Martinowich","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.07.021_bib44","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0092-8674(89)90430-3","article-title":"Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs","volume":"58","author":"Meehan","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib45","doi-asserted-by":"crossref","first-page":"5085","DOI":"10.1093\/nar\/20.19.5085","article-title":"Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA","volume":"20","author":"Meehan","year":"1992","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.molcel.2005.07.021_bib46","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1126\/science.1073354","article-title":"Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice","volume":"297","author":"Millar","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.molcel.2005.07.021_bib47","doi-asserted-by":"crossref","first-page":"4886","DOI":"10.1093\/nar\/21.21.4886","article-title":"Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2","volume":"21","author":"Nan","year":"1993","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.molcel.2005.07.021_bib48","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1128\/MCB.16.1.414","article-title":"DNA methylation specifies chromosomal localization of MeCP2","volume":"16","author":"Nan","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib49","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/30764","article-title":"Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex","volume":"393","author":"Nan","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2005.07.021_bib50","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/12659","article-title":"MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex","volume":"23","author":"Ng","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.molcel.2005.07.021_bib51","doi-asserted-by":"crossref","first-page":"4598","DOI":"10.1093\/nar\/29.22.4598","article-title":"Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation","volume":"29","author":"Nguyen","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.molcel.2005.07.021_bib52","doi-asserted-by":"crossref","first-page":"6653","DOI":"10.1093\/emboj\/18.23.6653","article-title":"Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1","volume":"18","author":"Ohki","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.molcel.2005.07.021_bib53","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0092-8674(01)00324-5","article-title":"Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA","volume":"105","author":"Ohki","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib54","first-page":"1114","article-title":"A systematic profile of DNA methylation in human cancer cell lines","volume":"63","author":"Paz","year":"2003","journal-title":"Cancer Res."},{"key":"10.1016\/j.molcel.2005.07.021_bib55","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1093\/emboj\/21.6.1389","article-title":"In vivo repression of an erythroid-specific gene by distinct corepressor complexes","volume":"21","author":"Rietveld","year":"2002","journal-title":"EMBO J."},{"key":"10.1016\/j.molcel.2005.07.021_bib56","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.molcel.2004.06.043","article-title":"Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly","volume":"15","author":"Sarraf","year":"2004","journal-title":"Mol. Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib57","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1091\/mbc.e03-11-0827","article-title":"High- and low-mobility populations of HP1 in heterochromatin of mammalian cells","volume":"15","author":"Schmiedeberg","year":"2004","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib58","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S1097-2765(03)00276-4","article-title":"A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos","volume":"12","author":"Stancheva","year":"2003","journal-title":"Mol. Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib59","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0092-8674(91)90214-J","article-title":"A matrix\/scaffold attachment region binding protein: identification, purification, and mode of binding","volume":"64","author":"von Kries","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2005.07.021_bib60","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1006\/jmbi.1999.3023","article-title":"The solution structure of the domain from MeCP2 that binds to methylated DNA","volume":"291","author":"Wakefield","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib61","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1101\/gad.2.9.1136","article-title":"Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus late promoter","volume":"2","author":"Watt","year":"1988","journal-title":"Genes Dev."},{"key":"10.1016\/j.molcel.2005.07.021_bib62","doi-asserted-by":"crossref","first-page":"5656","DOI":"10.1128\/MCB.17.9.5656","article-title":"Chicken MAR-binding protein ARBP is homologous to rat methyl-CpG-binding protein MeCP2","volume":"17","author":"Weitzel","year":"1997","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molcel.2005.07.021_bib63","doi-asserted-by":"crossref","first-page":"4172","DOI":"10.1093\/nar\/28.21.4172","article-title":"Functional consequences of Rett syndrome mutations on human MeCP2","volume":"28","author":"Yusufzai","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.molcel.2005.07.021_bib64","doi-asserted-by":"crossref","first-page":"6777","DOI":"10.1073\/pnas.1131928100","article-title":"Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function","volume":"100","author":"Zhao","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.molcel.2005.07.021_bib65","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1101\/gad.13.6.666","article-title":"Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP","volume":"13","author":"Zheng","year":"1999","journal-title":"Genes Dev."}],"container-title":["Molecular Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097276505015091?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097276505015091?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:03:47Z","timestamp":1761091427000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1097276505015091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9]]},"references-count":65,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,9]]}},"alternative-id":["S1097276505015091"],"URL":"https:\/\/doi.org\/10.1016\/j.molcel.2005.07.021","relation":{},"ISSN":["1097-2765"],"issn-type":[{"value":"1097-2765","type":"print"}],"subject":[],"published":{"date-parts":[[2005,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DNA Binding Selectivity of MeCP2 Due to a Requirement for A\/T Sequences Adjacent to Methyl-CpG","name":"articletitle","label":"Article Title"},{"value":"Molecular Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molcel.2005.07.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}