{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T22:46:00Z","timestamp":1793313960407,"version":"4.5.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T00:00:00Z","timestamp":1734739200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004189","name":"Max Planck Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004189","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Foundation","doi-asserted-by":"publisher","award":["NNF14CC0001"],"award-info":[{"award-number":["NNF14CC0001"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100024571","name":"Novo Nordisk Foundation Center for Protein Research, University of Copenhagen","doi-asserted-by":"publisher","award":["NNF15CC0001"],"award-info":[{"award-number":["NNF15CC0001"]}],"id":[{"id":"10.13039\/501100024571","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Cell"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.molcel.2024.12.023","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T10:54:55Z","timestamp":1736852095000},"page":"1008-1023.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Deciphering functional tumor-immune crosstalk through highly multiplexed imaging and deep visual proteomics"],"prefix":"10.1016","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7588-825X","authenticated-orcid":false,"given":"Xiang","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Mund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1292-4799","authenticated-orcid":false,"given":"Matthias","family":"Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molcel.2024.12.023_bib1","doi-asserted-by":"crossref","first-page":"5591","DOI":"10.1242\/jcs.116392","article-title":"The tumor microenvironment at a glance","volume":"125","author":"Balkwill","year":"2012","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.molcel.2024.12.023_bib2","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.ccell.2023.02.016","article-title":"The evolving tumor microenvironment: from cancer initiation to metastatic outgrowth","volume":"41","author":"de Visser","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.molcel.2024.12.023_bib3","doi-asserted-by":"crossref","first-page":"R921","DOI":"10.1016\/j.cub.2020.06.081","article-title":"The tumor microenvironment","volume":"30","author":"Anderson","year":"2020","journal-title":"Curr. Biol."},{"key":"10.1016\/j.molcel.2024.12.023_bib4","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/s41580-023-00615-w","article-title":"The technological landscape and applications of single-cell multi-omics","volume":"24","author":"Baysoy","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.molcel.2024.12.023_bib5","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/s12276-024-01186-2","article-title":"Advances in single-cell omics and multiomics for high-resolution molecular profiling","volume":"56","author":"Lim","year":"2024","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.molcel.2024.12.023_bib6","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.cell.2022.04.003","article-title":"Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays","volume":"185","author":"Chen","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2024.12.023_bib7","doi-asserted-by":"crossref","DOI":"10.1126\/science.abq4964","article-title":"The dawn of spatial omics","volume":"381","author":"Bressan","year":"2023","journal-title":"Science"},{"key":"10.1016\/j.molcel.2024.12.023_bib8","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/s41374-021-00714-2","article-title":"Conventional histological and cytological staining with simultaneous immunohistochemistry enabled by invisible chromogens","volume":"102","author":"Morrison","year":"2022","journal-title":"Lab. Invest."},{"key":"10.1016\/j.molcel.2024.12.023_bib9","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1016\/j.molcel.2022.05.022","article-title":"Unbiased spatial proteomics with single-cell resolution in tissues","volume":"82","author":"Mund","year":"2022","journal-title":"Mol. Cell"},{"key":"10.1016\/j.molcel.2024.12.023_bib10","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/j.ccell.2023.06.009","article-title":"Proteogenomic data and resources for pan-cancer analysis","volume":"41","author":"Li","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.molcel.2024.12.023_bib11","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/s41586-019-1173-8","article-title":"Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts","volume":"569","author":"Eckert","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2024.12.023_bib12","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.cell.2018.08.065","article-title":"Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer","volume":"175","author":"Coscia","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2024.12.023_bib13","doi-asserted-by":"crossref","first-page":"3921","DOI":"10.1016\/j.cell.2023.07.014","article-title":"Pan-cancer proteogenomics connects oncogenic drivers to functional states","volume":"186","author":"Li","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.molcel.2024.12.023_bib14","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nature19949","article-title":"Mass-spectrometric exploration of proteome structure and function","volume":"537","author":"Aebersold","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.molcel.2024.12.023_bib15","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1038\/s41587-022-01302-5","article-title":"Deep Visual proteomics defines single-cell identity and heterogeneity","volume":"40","author":"Mund","year":"2022","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.molcel.2024.12.023_bib16","doi-asserted-by":"crossref","DOI":"10.15252\/msb.202211503","article-title":"Robust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel","volume":"19","author":"Thielert","year":"2023","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.molcel.2024.12.023_bib17","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/s41587-022-01389-w","article-title":"Increasing the throughput of sensitive proteomics by plexDIA","volume":"41","author":"Derks","year":"2023","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.molcel.2024.12.023_bib18","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/s41592-023-01771-9","article-title":"Making single-cell proteomics biologically relevant","volume":"20","author":"Rosenberger","year":"2023","journal-title":"Nat. Methods"},{"key":"10.1016\/j.molcel.2024.12.023_bib19","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/s41573-018-0007-y","article-title":"Approaches to treat immune hot, altered and cold tumours with combination immunotherapies","volume":"18","author":"Galon","year":"2019","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.molcel.2024.12.023_bib20","doi-asserted-by":"crossref","DOI":"10.1126\/science.abf9419","article-title":"Tertiary lymphoid structures in cancer","volume":"375","author":"Schumacher","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.molcel.2024.12.023_bib21","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-05841-4","article-title":"MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T\u00a0cell treatment of solid tumors","volume":"12","author":"Kinkhabwala","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.molcel.2024.12.023_bib22","doi-asserted-by":"crossref","first-page":"e10798","DOI":"10.15252\/msb.202110798","article-title":"Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation","volume":"18","author":"Brunner","year":"2022","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.molcel.2024.12.023_bib23","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1038\/s41592-020-00998-0","article-title":"diaPASEF: parallel accumulation\u2013serial fragmentation combined with data-independent acquisition","volume":"17","author":"Meier","year":"2020","journal-title":"Nat. Methods"},{"key":"10.1016\/j.molcel.2024.12.023_bib24","doi-asserted-by":"crossref","first-page":"3290","DOI":"10.1021\/acs.jproteome.3c00357","article-title":"Evaluating the Performance of the Astral Mass Analyzer for Quantitative Proteomics Using Data-Independent Acquisition","volume":"22","author":"Heil","year":"2023","journal-title":"J.\u00a0Proteome Res."},{"key":"10.1016\/j.molcel.2024.12.023_bib25","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1038\/s41587-024-02129-y","article-title":"A new mass analyzer shakes up the proteomics field","volume":"42","author":"Kuster","year":"2024","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.molcel.2024.12.023_bib26","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/s41592-019-0638-x","article-title":"DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput","volume":"17","author":"Demichev","year":"2020","journal-title":"Nat. Methods"},{"key":"10.1016\/j.molcel.2024.12.023_bib27","doi-asserted-by":"crossref","first-page":"4414","DOI":"10.1158\/0008-5472.CAN-20-0069","article-title":"Spatial density and distribution of tumor-associated macrophages predict survival in non-small cell lung carcinoma","volume":"80","author":"Zheng","year":"2020","journal-title":"Cancer Res."},{"key":"10.1016\/j.molcel.2024.12.023_bib28","doi-asserted-by":"crossref","first-page":"E4041","DOI":"10.1073\/pnas.1720948115","article-title":"Macrophages impede CD8 T\u00a0cells from reaching tumor cells and limit the efficacy of anti\u2013PD-1 treatment","volume":"115","author":"Peranzoni","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.molcel.2024.12.023_bib29","article-title":"CD74 as a prognostic and M1 macrophage infiltration marker in a comprehensive pan-cancer analysis","volume":"14","author":"Li","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.molcel.2024.12.023_bib30","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-98637-x","article-title":"TYROBP, TLR4 and ITGAM regulated macrophages polarization and immune checkpoints expression in osteosarcoma","volume":"11","author":"Liang","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.molcel.2024.12.023_bib31","doi-asserted-by":"crossref","DOI":"10.1002\/iid3.934","article-title":"Immunomodulatory role of spleen tyrosine kinase in chronic inflammatory and autoimmune diseases","volume":"11","author":"Zhou","year":"2023","journal-title":"Immun. Inflamm. Dis."},{"key":"10.1016\/j.molcel.2024.12.023_bib32","article-title":"AIF1: Function and Connection with Inflammatory Diseases","volume":"12","author":"De Leon-Oliva","year":"2023","journal-title":"Biology (Basel)"},{"key":"10.1016\/j.molcel.2024.12.023_bib33","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0134-2020","article-title":"Metabolism in tumour-associated macrophages: A quid pro quo with the tumour microenvironment","volume":"29","author":"Zheng","year":"2020","journal-title":"Eur. Respir. Rev."},{"key":"10.1016\/j.molcel.2024.12.023_bib34","article-title":"Immune checkpoint therapy for solid tumours: clinical dilemmas and future trends","volume":"8","author":"Sun","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.molcel.2024.12.023_bib35","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0008-8749(91)90144-Z","article-title":"The coexpression of CD45RA and CD45RO isoforms on T\u00a0cells during the S\/G2\/M stages of cell cycle","volume":"138","author":"LaSalle","year":"1991","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.molcel.2024.12.023_bib36","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.cellimm.2008.08.007","article-title":"Relationship between CD107a expression and cytotoxic activity","volume":"254","author":"Aktas","year":"2009","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.molcel.2024.12.023_bib37","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/cmi.12580","article-title":"Macrophages: sentinels and regulators of the immune system","volume":"18","author":"Franken","year":"2016","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.molcel.2024.12.023_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1007081","article-title":"ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages","volume":"15","author":"Chan","year":"2019","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.molcel.2024.12.023_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/cmi.2013.47","article-title":"Crawling of effector T\u00a0cells on extracellular matrix: role of integrins in interstitial migration in inflamed tissues","volume":"11","author":"Kim","year":"2014","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.molcel.2024.12.023_bib40","article-title":"Effect of LAMA4 on Prognosis and Its Correlation with Immune Infiltration in Gastric Cancer","volume":"2021","author":"Wang","year":"2021","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.molcel.2024.12.023_bib41","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1016\/j.immuni.2023.06.017","article-title":"Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T\u00a0cells and reprogram them for immunosuppression","volume":"56","author":"Sattiraju","year":"2023","journal-title":"Immunity"},{"key":"10.1016\/j.molcel.2024.12.023_bib42","doi-asserted-by":"crossref","DOI":"10.1038\/s41419-021-03716-6","article-title":"HIF1\u03b1-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia","volume":"12","author":"Laquatra","year":"2021","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.molcel.2024.12.023_bib43","doi-asserted-by":"crossref","DOI":"10.1093\/narcan\/zcaa010","article-title":"Proteome dynamics analysis identifies functional roles of SDE2 and hypoxia in DNA damage response in prostate cancer cells","volume":"2","author":"Luo","year":"2020","journal-title":"NAR Cancer"},{"key":"10.1016\/j.molcel.2024.12.023_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2022.115321","article-title":"A current overview of RhoA, RhoB, and RhoC functions in vascular biology and pathology","volume":"206","author":"Eckenstaler","year":"2022","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.molcel.2024.12.023_bib45","unstructured":"Troul\u00e9, K., Petryszak, R., Prete, M., Cranley, J., Harasty, A., Tuong, Z.K., Teichmann, S.A., Garcia-Alonso, L., and Vento-Tormo, R. (2023). CellPhoneDB v5: inferring cell-cell communication from single-cell multiomics data. arXiv:2311.04567. https:\/\/doi.org\/10.48550\/arXiv.2311.04567."},{"key":"10.1016\/j.molcel.2024.12.023_bib46","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1038\/s41593-022-01097-3","article-title":"Identification of early neurodegenerative pathways in progressive multiple sclerosis","volume":"25","author":"Kaufmann","year":"2022","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.molcel.2024.12.023_bib47","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.ceb.2006.08.008","article-title":"CEACAMs: their role in physiology and pathophysiology","volume":"18","author":"Kuespert","year":"2006","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.molcel.2024.12.023_bib48","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2018.1434467","article-title":"The role of galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment","volume":"7","author":"Farhad","year":"2018","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.molcel.2024.12.023_bib49","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1038\/s41592-024-02565-3","article-title":"Method of the year 2024: spatial proteomics","volume":"21","year":"2024","journal-title":"Nat. Methods"},{"key":"10.1016\/j.molcel.2024.12.023_bib50","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/s41573-022-00520-5","article-title":"Macrophages as tools and targets in cancer therapy","volume":"21","author":"Mantovani","year":"2022","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.molcel.2024.12.023_bib51","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/s41417-021-00307-7","article-title":"TCR-like CARs and TCR-CARs targeting neoepitopes: an emerging potential","volume":"28","author":"Poorebrahim","year":"2021","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.molcel.2024.12.023_bib52","doi-asserted-by":"crossref","first-page":"D543","DOI":"10.1093\/nar\/gkab1038","article-title":"The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences","volume":"50","author":"Perez-Riverol","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.molcel.2024.12.023_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmb.2022.167505","article-title":"The BioImage Archive\u00a0\u2013 Building a Home for Life-Sciences Microscopy Data","volume":"434","author":"Hartley","year":"2022","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.molcel.2024.12.023_bib54","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1038\/nbt.2377","article-title":"A cross-platform toolkit for mass spectrometry and proteomics","volume":"30","author":"Chambers","year":"2012","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.molcel.2024.12.023_bib55","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nmeth.4256","article-title":"MSFragger: ultrafast and comprehensive peptide identification in mass spectrometry\u2013based proteomics","volume":"14","author":"Kong","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.molcel.2024.12.023_bib56","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1093\/bioinformatics\/btp101","article-title":"ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks","volume":"25","author":"Bindea","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.molcel.2024.12.023_bib57","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1021\/ac991131p","article-title":"Electrostatic Axially Harmonic Orbital Trapping: A High-Performance Technique of Mass Analysis","volume":"72","author":"Makarov","year":"2000","journal-title":"Anal. Chem."},{"key":"10.1016\/j.molcel.2024.12.023_bib58","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1038\/s41587-023-02099-7","article-title":"Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition","volume":"42","author":"Guzman","year":"2024","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.molcel.2024.12.023_bib59","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1093\/bioinformatics\/btz961","article-title":"iq: an R package to estimate relative protein abundances from ion quantification in DIA-MS-based proteomics","volume":"36","author":"Pham","year":"2020","journal-title":"Bioinformatics"},{"key":"10.1016\/j.molcel.2024.12.023_bib60","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/nmeth.3901","article-title":"The Perseus computational platform for comprehensive analysis of (prote)omics data","volume":"13","author":"Tyanova","year":"2016","journal-title":"Nat. Methods"},{"key":"10.1016\/j.molcel.2024.12.023_bib61","doi-asserted-by":"crossref","DOI":"10.1093\/bioinformatics\/btad461","article-title":"AlphaPeptStats: an open-source Python package for automated and scalable statistical analysis of mass spectrometry-based proteomics","volume":"39","author":"Krismer","year":"2023","journal-title":"Bioinformatics"}],"container-title":["Molecular Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097276524010414?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1097276524010414?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T12:12:14Z","timestamp":1741263134000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1097276524010414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":61,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S1097276524010414"],"URL":"https:\/\/doi.org\/10.1016\/j.molcel.2024.12.023","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.05.22.595266","asserted-by":"object"}]},"ISSN":["1097-2765"],"issn-type":[{"value":"1097-2765","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deciphering functional tumor-immune crosstalk through highly multiplexed imaging and deep visual proteomics","name":"articletitle","label":"Article Title"},{"value":"Molecular Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molcel.2024.12.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}