{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T14:57:16Z","timestamp":1772895436892,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2006,2,1]],"date-time":"2006-02-01T00:00:00Z","timestamp":1138752000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2006,2]]},"DOI":"10.1016\/j.molimm.2005.04.014","type":"journal-article","created":{"date-parts":[[2005,6,14]],"date-time":"2005-06-14T11:25:33Z","timestamp":1118748333000},"page":"579-587","source":"Crossref","is-referenced-by-count":14,"title":["Cloning and characterization of the human CD200 promoter region"],"prefix":"10.1016","volume":"43","author":[{"given":"Zhiqi","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip A.","family":"Marsden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reginald M.","family":"Gorczynski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.molimm.2005.04.014_bib1","first-page":"727","article-title":"Different reticular elements in rat lymphoid tissue identified by localization of Ia, Thy-1 and MRC OX-2 antigens","volume":"44","author":"Barclay","year":"1981","journal-title":"Immunology"},{"key":"10.1016\/j.molimm.2005.04.014_bib2","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S1471-4906(02)02223-8","article-title":"CD200 and membrane protein interactions in the control of myeloid cells","volume":"23","author":"Barclay","year":"2002","journal-title":"Trends Immunol."},{"key":"10.1016\/j.molimm.2005.04.014_bib3","doi-asserted-by":"crossref","first-page":"28882","DOI":"10.1074\/jbc.M002175200","article-title":"The POU domain transcription factor Tst-1 activates somatostatin receptor 1 gene expression in pancreatic beta-cells","volume":"275","author":"Baumeister","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molimm.2005.04.014_bib4","doi-asserted-by":"crossref","first-page":"4549","DOI":"10.4049\/jimmunol.158.10.4548","article-title":"MRC OX-2 defines a novel T cell costimulatory pathway","volume":"158","author":"Borriello","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2005.04.014_bib5","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/s003359900700","article-title":"Characterization and localization of Mox2, the gene encoding the murine homolog of the rat MRC OX-2 membrane glycoprotein","volume":"9","author":"Borriello","year":"1998","journal-title":"Mamm. Genome"},{"key":"10.1016\/j.molimm.2005.04.014_bib6","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S0925-4439(97)00058-6","article-title":"Cloning and characterization of the murine homologue of the rat\/human MRC OX-2 gene","volume":"1362","author":"Chen","year":"1997","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.molimm.2005.04.014_bib7","first-page":"51","article-title":"Microsatellites: evolution and mutational processes","volume":"197","author":"Freimer","year":"1996","journal-title":"Ciba. Found. Symp."},{"key":"10.1016\/j.molimm.2005.04.014_bib8","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1097\/00007890-199804270-00016","article-title":"Increased expression of the novel molecule Ox-2 is involved in prolongation of murine renal allograft survival","volume":"65","author":"Gorczynski","year":"1998","journal-title":"Transplantation"},{"key":"10.1016\/j.molimm.2005.04.014_bib9","doi-asserted-by":"crossref","first-page":"774","DOI":"10.4049\/jimmunol.162.2.774","article-title":"Evidence that an OX-2 positive cell can inhibit the stimulation of type-1 cytokine production by bone-marrow-derived B7-1 (and B7-2) positive dendritic cells","volume":"162","author":"Gorczynski","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2005.04.014_bib10","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.4049\/jimmunol.163.3.1654","article-title":"An immunoadhesin incorporating the molecule OX-2 is a potent immunosuppressant that prolongs allo- and xenograft survival","volume":"163","author":"Gorczynski","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2005.04.014_bib11","doi-asserted-by":"crossref","first-page":"4854","DOI":"10.4049\/jimmunol.165.9.4854","article-title":"Receptor engagement on cells expressing a ligand for the tolerance-inducing molecule OX2 induces an immunoregulation that inhibits alloreactivity in vitro and in vivo","volume":"165","author":"Gorczynski","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2005.04.014_bib12","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1006\/clim.2001.5117","article-title":"CD200 immunoadhesin suppresses collagen-induced arthritis in mice","volume":"101","author":"Gorczynski","year":"2001","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.molimm.2005.04.014_bib13","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1034\/j.1600-0897.2002.01094.x","article-title":"The same immunoregulatory molecules contribute to successful pregnancy and transplantation","volume":"48","author":"Gorczynski","year":"2002","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.molimm.2005.04.014_bib14","doi-asserted-by":"crossref","first-page":"33082","DOI":"10.1016\/S0021-9258(20)30099-5","article-title":"Structural organization of the human neuronal nitric oxidesynthase gene","volume":"269","author":"Hall","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molimm.2005.04.014_bib15","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1126\/science.290.5497.1768","article-title":"Down-regulation of the macrophage lineage through interaction with OX2 (CD200)","volume":"290","author":"Hoek","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.molimm.2005.04.014_bib16","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/(SICI)1096-9896(199603)178:3<239::AID-PATH506>3.0.CO;2-5","article-title":"Microsatellites and PCR genomic analysis","volume":"178","author":"Koreth","year":"1996","journal-title":"J. Pathol."},{"key":"10.1016\/j.molimm.2005.04.014_bib17","doi-asserted-by":"crossref","first-page":"3076","DOI":"10.1074\/jbc.274.5.3076","article-title":"Characterization of the human endothelial nitric-oxide synthase promoter","volume":"274","author":"Karantzoulis-Fegaras","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molimm.2005.04.014_bib18","doi-asserted-by":"crossref","first-page":"28545","DOI":"10.1074\/jbc.273.44.28545","article-title":"Biological role of the CCAAT\/Enhancer-binding protein family of transcription factors","volume":"273","author":"Lekstrom-Himes","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molimm.2005.04.014_bib19","doi-asserted-by":"crossref","first-page":"17478","DOI":"10.1016\/S0021-9258(19)85359-0","article-title":"Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene","volume":"268","author":"Marsden","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molimm.2005.04.014_bib20","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/BF00404426","article-title":"Characterization of the human homolog of the rat MRC OX-2 membrane glycoprotein","volume":"25","author":"McCaughan","year":"1987","journal-title":"Immunogenetics"},{"key":"10.1016\/j.molimm.2005.04.014_bib21","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0888-7543(89)90331-5","article-title":"The distribution of interspersed repetitive DNA sequences in the human genome","volume":"4","author":"Moyzis","year":"1989","journal-title":"Genomics"},{"key":"10.1016\/j.molimm.2005.04.014_bib22","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/83124","article-title":"Putting the brakes on innate immunity: a regulatory role for CD200?","volume":"2","author":"Nathan","year":"2001","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.molimm.2005.04.014_bib23","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1002\/eji.1830270814","article-title":"The leukocyte\/neuron cell surface antigen OX2 binds to a ligand on macrophages","volume":"27","author":"Preston","year":"1997","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.molimm.2005.04.014_bib24","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1182\/blood-2003-09-3184","article-title":"CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance","volume":"103","author":"Rosenblum","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.molimm.2005.04.014_bib25","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.1128\/MCB.8.8.3160","article-title":"Constitutive promoter directs expression of the nerve growth factor receptor gene","volume":"8","author":"Sehgal","year":"1988","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.molimm.2005.04.014_bib26","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0092-8674(89)90176-1","article-title":"The \u201cinitiator\u201d as a transcription control element","volume":"57","author":"Smale","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.molimm.2005.04.014_bib27","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S1074-7613(00)00023-6","article-title":"Lymphoid\/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function","volume":"13","author":"Wright","year":"2000","journal-title":"Immunity"},{"key":"10.1016\/j.molimm.2005.04.014_bib28","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/S0300-9084(03)00121-4","article-title":"Regulation of oct-1 gene transcription is different in lymphoid and non-lymphoid cells","volume":"85","author":"Zhenilo","year":"2003","journal-title":"Biochimie"}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589005001422?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589005001422?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T11:15:37Z","timestamp":1683112537000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589005001422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["S0161589005001422"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2005.04.014","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2006,2]]}}}