{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T16:07:35Z","timestamp":1770480455451,"version":"3.49.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Japanese Ministry of Health, Labor, and Welfare"},{"name":"Kagoshima University for Frontier Science Research Center Program"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1016\/j.molimm.2009.09.006","type":"journal-article","created":{"date-parts":[[2009,11,4]],"date-time":"2009-11-04T09:13:41Z","timestamp":1257326021000},"page":"606-613","source":"Crossref","is-referenced-by-count":16,"title":["Efficient induction of human T-cell leukemia virus-1-specific CTL by chimeric particle without adjuvant as a prophylactic for adult T-cell leukemia"],"prefix":"10.1016","volume":"47","author":[{"given":"Tomohiro","family":"Kozako","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiko","family":"Fukada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Hirata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohann","family":"White","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiko","family":"Harao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuharu","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youichiro","family":"Kino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Soeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Shimeno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Lemonnier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunro","family":"Sonoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomichi","family":"Arima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.molimm.2009.09.006_bib1","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/32183","article-title":"Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs","volume":"392","author":"Albert","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.molimm.2009.09.006_bib2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/(SICI)1097-0320(19991101)37:3<197::AID-CYTO6>3.0.CO;2-L","article-title":"Annexin V used for measuring apoptosis in the early events of cellular cytotoxicity","volume":"37","author":"Aubry","year":"1999","journal-title":"Cytometry"},{"key":"10.1016\/j.molimm.2009.09.006_bib3","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/32588","article-title":"Dendritic cells and the control of immunity","volume":"392","author":"Banchereau","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.molimm.2009.09.006_bib4","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1182\/blood-2008-06-163071","article-title":"HTLV-1 infection: role of CTL efficiency","volume":"112","author":"Bangham","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.molimm.2009.09.006_bib5","doi-asserted-by":"crossref","first-page":"7587","DOI":"10.4049\/jimmunol.178.12.7587","article-title":"Uptake of human papillomavirus virus-like particles by dendritic cells is mediated by Fcgamma receptors and contributes to acquisition of T cell immunity","volume":"178","author":"Da Silva","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.09.006_bib6","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ymeth.2006.07.018","article-title":"Virus-like particles: passport to immune recognition","volume":"40","author":"Grgacic","year":"2006","journal-title":"Methods"},{"key":"10.1016\/j.molimm.2009.09.006_bib7","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1158\/0008-5472.CAN-03-1452","article-title":"Graft-versus-Tax response in adult T-cell leukemia patients after hematopoietic stem cell transplantation","volume":"64","author":"Harashima","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.molimm.2009.09.006_bib8","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.1128\/JVI.61.11.3543-3549.1987","article-title":"Expression of hepatitis B virus middle and large surface antigen genes in Saccharomyces cerevisiae","volume":"61","author":"Imamura","year":"1987","journal-title":"J. Virol."},{"key":"10.1016\/j.molimm.2009.09.006_bib9","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/348245a0","article-title":"Circulating CD8+ cytotoxic T lymphocytes specific for HTLV-I pX in patients with HTLV-I associated neurological disease","volume":"348","author":"Jacobson","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.molimm.2009.09.006_bib10","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.2741\/2814","article-title":"Dendritic cell based personalized immunotherapy based on cancer antigen research","volume":"13","author":"Kawakami","year":"2008","journal-title":"Front. Biosci."},{"key":"10.1016\/j.molimm.2009.09.006_bib11","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1099\/vir.0.81582-0","article-title":"Chimeric peptide vaccine composed of B- and T-cell epitopes of human T-cell leukemia virus type 1 induces humoral and cellular immune responses and reduces the proviral load in immunized squirrel monkeys (Saimiri sciureus)","volume":"87","author":"Kazanji","year":"2006","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.molimm.2009.09.006_bib12","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1158\/1078-0432.CCR-05-2267","article-title":"Identification of HLA-A2- or HLA-A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy of hepatocellular carcinoma","volume":"12","author":"Komori","year":"2006","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.molimm.2009.09.006_bib13","doi-asserted-by":"crossref","first-page":"5718","DOI":"10.4049\/jimmunol.177.8.5718","article-title":"Reduced frequency, diversity, and function of human T cell leukemia virus type 1-specific CD8+ T cell in adult T cell leukemia patients","volume":"177","author":"Kozako","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.09.006_bib14","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/leu.2008.272","article-title":"PD-1\/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia\/lymphoma patients","volume":"23","author":"Kozako","year":"2009","journal-title":"Leukemia"},{"key":"10.1016\/j.molimm.2009.09.006_bib15","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/329547a0","article-title":"Antibody production to the nucleocapsid and envelope of the hepatitis B virus primed by a single synthetic T cell site","volume":"329","author":"Milich","year":"1987","journal-title":"Nature"},{"key":"10.1016\/j.molimm.2009.09.006_bib16","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1128\/JVI.59.1.176-180.1986","article-title":"Expression of hepatitis B virus core antigen gene in Saccharomyces cerevisiae: synthesis of two polypeptides translated from different initiation codons","volume":"59","author":"Miyanohara","year":"1986","journal-title":"J. Virol."},{"key":"10.1016\/j.molimm.2009.09.006_bib17","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1084\/jem.185.12.2043","article-title":"HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice","volume":"185","author":"Pascolo","year":"1997","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.molimm.2009.09.006_bib18","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1002\/ijc.21781","article-title":"Combined prophylactic and therapeutic cancer vaccine: enhancing CTL responses to HPV16 E2 using a chimeric VLP in HLA-A2 mice","volume":"118","author":"Qian","year":"2006","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.molimm.2009.09.006_bib19","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1182\/blood-2002-07-2254","article-title":"Generation and genetic modification of dendritic cells derived from mouse embryonic stem cells","volume":"101","author":"Senju","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.molimm.2009.09.006_bib20","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0378-1119(91)90193-F","article-title":"Production of hepatitis B virion-like particles in yeast","volume":"106","author":"Shiosaki","year":"1991","journal-title":"Gene"},{"key":"10.1016\/j.molimm.2009.09.006_bib21","doi-asserted-by":"crossref","first-page":"2880","DOI":"10.4049\/jimmunol.168.6.2880","article-title":"Critical role for activation of antigen-presenting cells in priming of cytotoxic T cell responses after vaccination with virus-like particles","volume":"168","author":"Storni","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.09.006_bib22","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1146\/annurev.immunol.15.1.15","article-title":"Human T cell leukemia virus type I (HTLV-I) and human diseases","volume":"15","author":"Uchiyama","year":"1997","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.molimm.2009.09.006_bib23","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1182\/blood.V97.10.3177","article-title":"Impaired production of naive T lymphocytes in human T-cell leukemia virus type I-infected individuals: its implications in the immunodeficient state","volume":"97","author":"Yasunaga","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.molimm.2009.09.006_bib24","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1016\/j.molimm.2009.03.008","article-title":"Virus-like particle vaccine activates conventional B2 cells and promotes B cell differentiation to IgG2a producing plasma cells","volume":"46","author":"Zhang","year":"2009","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.molimm.2009.09.006_bib25","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.cellimm.2007.07.003","article-title":"Generation of chimeric HBc proteins with epitopes in E. coli: formation of virus-like particles and a potent inducer of antigen-specific cytotoxic immune response and anti-tumor effect in vivo","volume":"247","author":"Zhang","year":"2007","journal-title":"Cell. Immunol."}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589009007081?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589009007081?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T11:59:00Z","timestamp":1590235140000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589009007081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":25,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["S0161589009007081"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2009.09.006","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}