{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:11:25Z","timestamp":1759961485707},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1016\/j.molimm.2009.10.017","type":"journal-article","created":{"date-parts":[[2009,11,24]],"date-time":"2009-11-24T09:47:57Z","timestamp":1259056077000},"page":"671-677","source":"Crossref","is-referenced-by-count":11,"title":["Complement factor 7 gene mutations in relation to meningococcal infection and clinical recurrence of meningococcal disease"],"prefix":"10.1016","volume":"47","author":[{"given":"Taco W.","family":"Kuijpers","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla Th. P.","family":"Hopman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ed","family":"Nieuwenhuys","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Dewald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arjan C.","family":"Lankester","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Roos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arie","family":"van der Ende","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cees","family":"Fijen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"de Boer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.molimm.2009.10.017_bib1","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1111\/j.1365-2567.2004.01997.x","article-title":"Complement component C7 deficiency in two Spanish families","volume":"113","author":"Barroso","year":"2004","journal-title":"Immunology"},{"key":"10.1016\/j.molimm.2009.10.017_bib2","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1365-2567.2006.02364.x","article-title":"Molecular defects of the C7 gene in two patients with complement C7 deficiency","volume":"118","author":"Barroso","year":"2006","journal-title":"Immunology"},{"key":"10.1016\/j.molimm.2009.10.017_bib3","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/ajmg.10393","article-title":"C7 complement deficiency in an Israeli Arab village","volume":"110","author":"Behar","year":"2002","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.molimm.2009.10.017_bib4","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1159\/000154235","article-title":"A common Ser\/Thr polymorphism in the perforin-homologous region of human complement component C7","volume":"44","author":"Dewald","year":"1994","journal-title":"Hum. Hered."},{"key":"10.1016\/j.molimm.2009.10.017_bib5","doi-asserted-by":"crossref","first-page":"17087","DOI":"10.1016\/S0021-9258(18)41897-2","article-title":"Formation and structure of the C5b-7 complex of the lytic pathway of complement","volume":"267","author":"DiScipio","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molimm.2009.10.017_bib6","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0021-9258(19)57427-0","article-title":"The structure of human complement component C7 and the C5b-7 complex","volume":"263","author":"DiScipio","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molimm.2009.10.017_bib7","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1046\/j.1365-2249.2003.02099.x","article-title":"Restricted genetic defects underlie human complement C6 deficiency","volume":"132","author":"Dragon-Durey","year":"2003","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib8","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s004390050859","article-title":"Complement C7 deficiency: seven further molecular defects and their associated marker haplotypes","volume":"103","author":"Fernie","year":"1998","journal-title":"Hum. Genet."},{"key":"10.1016\/j.molimm.2009.10.017_bib9","doi-asserted-by":"crossref","first-page":"3648","DOI":"10.4049\/jimmunol.157.8.3648","article-title":"Molecular bases of combined subtotal deficiencies of C6 and C7: their effects in combination with other C6 and C7 deficiencies","volume":"157","author":"Fernie","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib10","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.4049\/jimmunol.159.2.1019","article-title":"Molecular bases of C7 deficiency: three different defects","volume":"159","author":"Fernie","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib11","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1086\/515075","article-title":"Assessment of complement deficiency in patients with meningococcal disease in The Netherlands","volume":"28","author":"Fijen","year":"1999","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.molimm.2009.10.017_bib12","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1002\/ajmg.1183","article-title":"High prevalence of complement C7 deficiency among healthy blood donors of Moroccan Jewish ancestry","volume":"99","author":"Halle","year":"2001","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.molimm.2009.10.017_bib13","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1744-313X.1978.tb00641.x","article-title":"Inherited structural variation and linkage relationship of C7","volume":"5","author":"Hobart","year":"1978","journal-title":"J. Immunogenet."},{"key":"10.1016\/j.molimm.2009.10.017_bib14","doi-asserted-by":"crossref","first-page":"5188","DOI":"10.4049\/jimmunol.154.10.5188","article-title":"Structure of the human C7 gene and comparison with the C6, C8A, C8B, and C9 genes","volume":"154","author":"Hobart","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib15","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/0161-5890(88)90169-1","article-title":"The distortive mechanism for the activation of complement component C1 supported by studies with a monoclonal antibody against the \u201carms\u201d of C1q","volume":"25","author":"Hoekzema","year":"1988","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib16","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0006-291X(02)02481-6","article-title":"Molecular bases for human complement C7 polymorphisms C7*3 and C7*4","volume":"298","author":"Horiuchi","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.molimm.2009.10.017_bib17","doi-asserted-by":"crossref","first-page":"9347","DOI":"10.1016\/S0021-9258(19)50430-6","article-title":"Type I human complement C2 deficiency. A 28-base pair gene deletion causes skipping of exon 6 during RNA splicing","volume":"267","author":"Johnson","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molimm.2009.10.017_bib18","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/s10875-006-9006-6","article-title":"Two mutations of the C7 gene, c.1424G>A and c.281-1G>T, in two Korean families","volume":"26","author":"Kang","year":"2006","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib19","doi-asserted-by":"crossref","first-page":"220","DOI":"10.3346\/jkms.2005.20.2.220","article-title":"Two novel mutations in the C7 gene in a Korean patient with complement C7 deficiency","volume":"20","author":"Ki","year":"2005","journal-title":"J. Korean Med. Sci."},{"key":"10.1016\/j.molimm.2009.10.017_bib20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1046\/j.1365-2249.2000.01238.x","article-title":"The endothelium is an extrahepatic site of synthesis of the seventh component of the complement system","volume":"121","author":"Langeggen","year":"2000","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib21","doi-asserted-by":"crossref","first-page":"4510","DOI":"10.1128\/IAI.60.11.4510-4516.1992","article-title":"Antibodies to meningococcal class 1 outer membrane proteins in South African complement-deficient and complement-sufficient subjects","volume":"60","author":"Orren","year":"1992","journal-title":"Infect. Immun."},{"key":"10.1016\/j.molimm.2009.10.017_bib22","first-page":"147","article-title":"Class 1\/3 outer membrane protein vaccine against group B, type 15, subtype 16 meningococci","volume":"63","author":"Poolman","year":"1986","journal-title":"Dev. Biol. Stand."},{"key":"10.1016\/j.molimm.2009.10.017_bib23","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1002\/eji.200636812","article-title":"Hereditary complement C7 deficiency in nine families: subtotal C7 deficiency revisited","volume":"37","author":"Rameix-Welti","year":"2007","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib24","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/BF00210475","article-title":"A physical map of the human complement component C6, C7, and C9 genes","volume":"38","author":"Setien","year":"1993","journal-title":"Immunogenetics"},{"key":"10.1016\/j.molimm.2009.10.017_bib25","doi-asserted-by":"crossref","first-page":"4547","DOI":"10.4049\/jimmunol.173.7.4547","article-title":"Complement components C5 and C7: Recombinant factor I modules of C7 bind to the C345C domain of C5","volume":"173","author":"Thai","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib26","doi-asserted-by":"crossref","first-page":"6227","DOI":"10.4049\/jimmunol.174.10.6227","article-title":"Recombinant C345C and factor I modules of complement components C5 and C7 inhibit C7 incorporation into the complement membrane attack complex","volume":"174","author":"Thai","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib27","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1046\/j.1365-2249.2003.02186.x","article-title":"Complement component C7 deficiency in a Spanish family","volume":"133","author":"Vazquez-Bermudez","year":"2003","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib28","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1056\/NEJM200104053441406","article-title":"Complement. First of two parts","volume":"344","author":"Walport","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.molimm.2009.10.017_bib29","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1056\/NEJM200104123441506","article-title":"Complement. Second of two parts","volume":"344","author":"Walport","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.molimm.2009.10.017_bib30","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/BF01891239","article-title":"Human C7 polymorphism: quantitative analysis of different phenotypes","volume":"33","author":"Washio","year":"1982","journal-title":"Jpn. J. Hum. Genet."},{"key":"10.1016\/j.molimm.2009.10.017_bib31","doi-asserted-by":"crossref","first-page":"4624","DOI":"10.4049\/jimmunol.152.9.4624","article-title":"Assessment of in vivo synthesis after liver transplantation reveals that hepatocytes do not synthesize the majority of human C7","volume":"152","author":"Wurzner","year":"1994","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib32","doi-asserted-by":"crossref","first-page":"4813","DOI":"10.4049\/jimmunol.154.9.4813","article-title":"Molecular basis of the complement C7 M\/N polymorphism. A neutral amino acid substitution outside the epitope of the allospecific monoclonal antibody WU 4-15","volume":"154","author":"Wurzner","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2009.10.017_bib33","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1172\/JCI117868","article-title":"Molecular basis of subtotal complement C6 deficiency. A carboxy-terminally truncated but functionally active C6","volume":"95","author":"Wurzner","year":"1995","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.molimm.2009.10.017_bib34","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1159\/000019082","article-title":"Reference typing report for complement components C6, C7 and C9, including mutations leading to deficiencies","volume":"15","author":"Wurzner","year":"1998","journal-title":"Exp. Clin. Immunogenet."}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589009007901?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589009007901?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T17:11:27Z","timestamp":1685207487000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589009007901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["S0161589009007901"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2009.10.017","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2010,1]]}}}