{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:19:06Z","timestamp":1759331946730},"reference-count":72,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100014364","name":"National Children\u2019s Research Centre","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100014364","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.molimm.2015.06.026","type":"journal-article","created":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T02:37:38Z","timestamp":1436841458000},"page":"369-376","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"PB","title":["IgG anti-tTG responses in different autoimmune conditions differ in their epitope targets and subclass usage"],"prefix":"10.1016","volume":"67","author":[{"given":"Ross","family":"Comerford","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacinta","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Conleth","family":"Feighery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg","family":"Byrne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.molimm.2015.06.026_bib0005","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/00005176-200301000-00015","article-title":"Tissue transglutaminase immunoglobulin isotypes in children with untreated and treated celiac disease","volume":"36","author":"Agardh","year":"2003","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"issue":"4","key":"10.1016\/j.molimm.2015.06.026_bib0010","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1210\/edrv-15-4-516","article-title":"Insulin-dependent diabetes mellitus as an autoimmune disease","volume":"15","author":"Bach","year":"1994","journal-title":"Endocr. Rev."},{"issue":"1","key":"10.1016\/j.molimm.2015.06.026_bib0015","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s00726-011-1188-4","article-title":"Recent advances in the development of tissue transglutaminase (TG2) inhibitors","volume":"44","author":"Badarau","year":"2013","journal-title":"Amino Acids"},{"key":"10.1016\/j.molimm.2015.06.026_bib0020","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.yapd.2008.07.001","article-title":"Celiac disease: pathophysiology, clinical manifestations, and associated autoimmune conditions","volume":"55","author":"Barker","year":"2008","journal-title":"Adv. Pediatr."},{"issue":"Suppl. 1","key":"10.1016\/j.molimm.2015.06.026_bib0025","first-page":"S401","article-title":"Celiac disease in type-I diabetes mellitus: coexisting phenomenon","volume":"16","author":"Bashiri","year":"2011","journal-title":"J. Res. Med. Sci."},{"key":"10.1016\/j.molimm.2015.06.026_bib0030","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/1471-2148-8-166","article-title":"Developmental expression of the alpha-skeletal actin gene","volume":"8","author":"Bertola","year":"2008","journal-title":"BMC Evol. Biol."},{"issue":"12","key":"10.1016\/j.molimm.2015.06.026_bib0035","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1023\/B:DDAS.0000007875.72256.e8","article-title":"IgA and IgG tissue transglutaminase antibody prevalence and clinical significance in connective tissue diseases, inflammatory bowel disease, and primary biliary cirrhosis","volume":"48","author":"Bizzaro","year":"2003","journal-title":"Dig. Dis. Sci."},{"issue":"1","key":"10.1016\/j.molimm.2015.06.026_bib0040","doi-asserted-by":"crossref","first-page":"525","DOI":"10.4049\/jimmunol.163.1.525","article-title":"Early autoantibody responses in prediabetes are IgG1 dominated and suggest antigen-specific regulation","volume":"163","author":"Bonifacio","year":"1999","journal-title":"J. Immunol."},{"issue":"12","key":"10.1016\/j.molimm.2015.06.026_bib0045","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1007\/s00125-006-0465-3","article-title":"Increased intestinal permeability precedes clinical onset of type 1 diabetes","volume":"49","author":"Bosi","year":"2006","journal-title":"Diabetologia"},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0050","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.imlet.2006.03.004","article-title":"The changing immunological paradigm in coeliac disease","volume":"105","author":"Brandtzaeg","year":"2006","journal-title":"Immunol. Lett."},{"issue":"5","key":"10.1016\/j.molimm.2015.06.026_bib0055","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.4049\/jimmunol.153.5.2268","article-title":"Autoantibodies to human nuclear lamin B2 protein. Epitope specificity in different autoimmune diseases","volume":"153","author":"Brito","year":"1994","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.molimm.2015.06.026_bib0060","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1136\/gut.2006.092908","article-title":"Mutagenesis of the catalytic triad of tissue transglutaminase abrogates coeliac disease serum IgA autoantibody binding","volume":"56","author":"Byrne","year":"2007","journal-title":"Gut"},{"issue":"3","key":"10.1016\/j.molimm.2015.06.026_bib0065","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.clim.2010.04.017","article-title":"Coeliac disease autoantibodies mediate significant inhibition of tissue transglutaminase","volume":"136","author":"Byrne","year":"2010","journal-title":"Clin. Immunol."},{"issue":"3","key":"10.1016\/j.molimm.2015.06.026_bib0070","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1136\/gut.47.3.366","article-title":"IgG(1) antiendomysium and IgG antitissue transglutaminase (anti-tTG) antibodies in coeliac patients with selective IgA deficiency. Working groups on celiac disease of SIGEP and Club del Tenue","volume":"47","author":"Cataldo","year":"2000","journal-title":"Gut"},{"issue":"4","key":"10.1016\/j.molimm.2015.06.026_bib0075","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1097\/MPG.0b013e318251419f","article-title":"Binding of autoantibodies to the core region of tissue transglutaminase is a feature of paediatric coeliac disease","volume":"55","author":"Comerford","year":"2012","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"issue":"4","key":"10.1016\/j.molimm.2015.06.026_bib0080","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1002\/1529-0131(199904)42:4<742::AID-ANR18>3.0.CO;2-I","article-title":"Cytokine profiles in Wegener\u2019s granulomatosis: predominance of type 1 (Th1) in the granulomatous inflammation","volume":"42","author":"Csernok","year":"1999","journal-title":"Arthritis Rheum."},{"issue":"3","key":"10.1016\/j.molimm.2015.06.026_bib0085","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/nm.2656","article-title":"High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions","volume":"18","author":"Di Niro","year":"2012","journal-title":"Nat. Med."},{"issue":"6","key":"10.1016\/j.molimm.2015.06.026_bib0090","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1467-789X.2010.00845.x","article-title":"Leaky gut and diabetes mellitus: what is the link?","volume":"12","author":"de Kort","year":"2011","journal-title":"Obes Rev."},{"issue":"6","key":"10.1016\/j.molimm.2015.06.026_bib0095","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1255\/ejms.1040","article-title":"Mass spectrometric and peptide chip epitope mapping of rheumatoid arthritis autoantigen RA33","volume":"15","author":"El-Kased","year":"2009","journal-title":"Eur. J. Mass Spectrom. (Chichester, Engl.)"},{"issue":"1 Suppl. 64","key":"10.1016\/j.molimm.2015.06.026_bib0100","first-page":"S57","article-title":"Distinct proteinase 3-induced cytokine patterns in Wegener\u2019s granulomatosis, Churg\u2013Strauss syndrome, and healthy controls","volume":"29","author":"Fagin","year":"2011","journal-title":"Clin. Exp. Rheumatol."},{"issue":"7","key":"10.1016\/j.molimm.2015.06.026_bib0105","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/sj.cdd.4400880","article-title":"Presence of anti-tissue transglutaminase antibodies in inflammatory intestinal diseases: an apoptosis-associated event?","volume":"8","author":"Farrace","year":"2001","journal-title":"Cell Death Differ."},{"issue":"9","key":"10.1016\/j.molimm.2015.06.026_bib0110","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1155\/2007\/917649","article-title":"Granuloma-positive Crohn\u2019s disease","volume":"21","author":"Freeman","year":"2007","journal-title":"Can. J. Gastroenterol."},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0115","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.4049\/jimmunol.169.2.1068","article-title":"Characterization of autoreactive T cells to the autoantigens heterogeneous nuclear ribonucleoprotein A2 (RA33) and filaggrin in patients with rheumatoid arthritis","volume":"169","author":"Fritsch","year":"2002","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.molimm.2015.06.026_bib0120","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1365-2567.2011.03411.x","article-title":"Human IgG isotypes and activating Fc\u03b3 receptors in the interaction of Salmonella enterica serovar Typhimurium with phagocytic cells","volume":"133","author":"Goh","year":"2011","journal-title":"Immunology"},{"issue":"Pt 2","key":"10.1016\/j.molimm.2015.06.026_bib0125","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1042\/bj20021234","article-title":"Transglutaminases: nature\u2019s biological glues","volume":"368","author":"Griffin","year":"2002","journal-title":"Biochem. J."},{"issue":"6","key":"10.1016\/j.molimm.2015.06.026_bib0130","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s10875-006-9045-z","article-title":"Double reactivity against actin and alpha-actinin defines a severe form of autoimmune hepatitis type 1","volume":"26","author":"Gueguen","year":"2006","journal-title":"J. Clin. Immunol."},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0135","doi-asserted-by":"crossref","first-page":"228","DOI":"10.2337\/diacare.23.2.228","article-title":"Antibodies to IA-2 and GAD65 in type 1 and type 2 diabetes: isotype restriction and polyclonality","volume":"23","author":"Hawa","year":"2000","journal-title":"Diabetes Care"},{"issue":"3","key":"10.1016\/j.molimm.2015.06.026_bib0140","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1002\/hep.22271","article-title":"Significance of autoantibodies","volume":"47","author":"Herkel","year":"2008","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.molimm.2015.06.026_bib0145","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1046\/j.1523-1755.1999.00369.x","article-title":"Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis","volume":"55","author":"Holdsworth","year":"1999","journal-title":"Kidney Int."},{"issue":"5","key":"10.1016\/j.molimm.2015.06.026_bib0150","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1136\/gut.33.5.632","article-title":"Serum IgG subclass antibodies to a variety of food antigens in patients with coeliac disease","volume":"33","author":"Hvatum","year":"1992","journal-title":"Gut"},{"issue":"7","key":"10.1016\/j.molimm.2015.06.026_bib0155","first-page":"1260","article-title":"Clinical utility and serological connections of anti-RA33 antibodies in systemic lupus erythematosus","volume":"21","author":"Isenberg","year":"1994","journal-title":"J. Rheumatol."},{"issue":"1\u20132","key":"10.1016\/j.molimm.2015.06.026_bib0160","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3109\/08916938909029144","article-title":"Quantitation of autoantibody-secreting B cells in systemic lupus erythematosus","volume":"5","author":"Ishigatsubo","year":"1989","journal-title":"Autoimmunity"},{"issue":"12","key":"10.1016\/j.molimm.2015.06.026_bib0165","doi-asserted-by":"crossref","first-page":"5981","DOI":"10.4049\/jimmunol.1300183","article-title":"Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells","volume":"190","author":"Iversen","year":"2013","journal-title":"J. Immunol."},{"issue":"Suppl. 1","key":"10.1016\/j.molimm.2015.06.026_bib0170","doi-asserted-by":"crossref","first-page":"i59","DOI":"10.1136\/ard.2010.138024","article-title":"Pathogenesis of ANCA-associated vasculitides","volume":"70","author":"Kallenberg","year":"2011","journal-title":"Ann. Rheum. Dis."},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0175","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1084\/jem.180.2.595","article-title":"Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish stiff-man syndrome from insulin-dependent diabetes mellitus","volume":"180","author":"Kim","year":"1994","journal-title":"J. Exp. Med."},{"issue":"1","key":"10.1016\/j.molimm.2015.06.026_bib0180","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0197-0186(01)00064-X","article-title":"Transglutaminases in disease","volume":"40","author":"Kim","year":"2002","journal-title":"Neurochem. Int."},{"issue":"11","key":"10.1016\/j.molimm.2015.06.026_bib0185","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1136\/gut.52.11.1567","article-title":"Elevation of IgG antibodies against tissue transglutaminase as a diagnostic tool for coeliac disease in selective IgA deficiency","volume":"52","author":"Korponay-Szabo","year":"2003","journal-title":"Gut"},{"issue":"10","key":"10.1016\/j.molimm.2015.06.026_bib0190","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1007\/s001250051291","article-title":"Antibodies to tissue transglutaminase C in type I diabetes","volume":"42","author":"Lampasona","year":"1999","journal-title":"Diabetologia"},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0195","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1159\/000076440","article-title":"Antigen-specific versus total immunoglobulin synthesis: total IgE and IgG1, but not IgG2a levels predict murine antigen-specific responses","volume":"133","author":"Lewkowich","year":"2004","journal-title":"Int. Arch. Allergy Immunol."},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0200","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/nrm1014","article-title":"Transglutaminases: crosslinking enzymes with pleiotropic functions","volume":"4","author":"Lorand","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"7","key":"10.1016\/j.molimm.2015.06.026_bib0205","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.2337\/db08-0962","article-title":"Majority of children with type 1 diabetes produce and deposit anti-tissue transglutaminase antibodies in the small intestine","volume":"58","author":"Maglio","year":"2009","journal-title":"Diabetes"},{"issue":"4","key":"10.1016\/j.molimm.2015.06.026_bib0210","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1191\/0961203304lu1004oa","article-title":"IgA and IgG tissue transglutaminase antibodies in systemic lupus erythematosus","volume":"13","author":"Marai","year":"2004","journal-title":"Lupus"},{"issue":"Suppl. 3","key":"10.1016\/j.molimm.2015.06.026_bib0215","doi-asserted-by":"crossref","first-page":"S158","DOI":"10.1016\/S0399-8320(09)73151-3","article-title":"Biological markers in inflammatory bowel disease: practical consideration for clinicians","volume":"33","author":"Mendoza","year":"2009","journal-title":"Gastroenterol. Clin. Biol."},{"issue":"8","key":"10.1016\/j.molimm.2015.06.026_bib0220","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.2337\/db08-1579","article-title":"Diabetes-specific HLA-DR-restricted proinflammatory T-cell response to wheat polypeptides in tissue transglutaminase antibody-negative patients with type 1 diabetes","volume":"58","author":"Mojibian","year":"2009","journal-title":"Diabetes"},{"issue":"3","key":"10.1016\/j.molimm.2015.06.026_bib0225","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1111\/j.1365-2249.2005.02862.x","article-title":"Circulating anti-actin and anti-ATP synthase antibodies identify a sub-set of patients with idiopathic nephrotic syndrome","volume":"141","author":"Musante","year":"2005","journal-title":"Clin. Exp. Immunol."},{"issue":"3","key":"10.1016\/j.molimm.2015.06.026_bib0230","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1093\/ndt\/gfg616","article-title":"Distribution of glomerular IgG subclass deposits in malignancy-associated membranous nephropathy","volume":"19","author":"Ohtani","year":"2004","journal-title":"Nephrol. Dial. Transplant."},{"issue":"11","key":"10.1016\/j.molimm.2015.06.026_bib0235","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.1111\/j.1572-0241.2002.07033.x","article-title":"Tissue transglutaminase antibodies in patients with end-stage heart failure","volume":"97","author":"Peracchi","year":"2002","journal-title":"Am. J. Gastroenterol."},{"issue":"5","key":"10.1016\/j.molimm.2015.06.026_bib0240","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1097\/00126334-200108150-00015","article-title":"Antitissue transglutaminase antibodies in HIV infection and effect of highly active antiretroviral therapy","volume":"27","author":"Pereda","year":"2001","journal-title":"J. Acquir. Immune Defic. Syndr."},{"issue":"12","key":"10.1016\/j.molimm.2015.06.026_bib0245","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1373\/clinchem.2003.023234","article-title":"Anti-tissue transglutaminase antibodies in arthritic patients: a disease-specific finding?","volume":"49","author":"Picarelli","year":"2003","journal-title":"Clin. Chem."},{"issue":"3","key":"10.1016\/j.molimm.2015.06.026_bib0250","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1046\/j.1365-2249.1999.01030.x","article-title":"Comparative analysis of epitope recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different autoimmune disorders","volume":"118","author":"Powers","year":"1999","journal-title":"Clin. Exp. Immunol."},{"issue":"9","key":"10.1016\/j.molimm.2015.06.026_bib0255","doi-asserted-by":"crossref","first-page":"453","DOI":"10.4321\/S1130-01082011000900003","article-title":"Anti-tissue transglutaminase antibodies (IgA and IgG) in both Crohn\u2019s disease and autoimmune diabetes","volume":"103","author":"Ribeiro-Cabral","year":"2011","journal-title":"Rev. Esp. Enferm. Dig."},{"issue":"5","key":"10.1016\/j.molimm.2015.06.026_bib0260","first-page":"920","article-title":"Antibodies to tissue transglutaminase and Saccharomyces cerevisiae in ankylosing spondylitis and psoriatic arthritis","volume":"31","author":"Riente","year":"2004","journal-title":"J. Rheumatol."},{"issue":"4 Suppl. 1","key":"10.1016\/j.molimm.2015.06.026_bib0265","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1053\/j.gastro.2005.02.028","article-title":"The diagnostic accuracy of serologic tests for celiac disease: a systematic review","volume":"128","author":"Rostom","year":"2005","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.molimm.2015.06.026_bib0270","first-page":"12","article-title":"Antibodies against transglutaminases: peptidylarginine deiminase and citrulline in rheumatoid arthritis\u2013new pathways to epitope spreading","volume":"24","author":"Roth","year":"2006","journal-title":"Clin. Exp. Rheumatol."},{"issue":"1\u20132","key":"10.1016\/j.molimm.2015.06.026_bib0275","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.cca.2006.08.006","article-title":"Tissue transglutaminase ELISA positivity in autoimmune disease independent of gluten-sensitive disease","volume":"376","author":"S\u00e1rdy","year":"2007","journal-title":"Clin. Chim. Acta"},{"issue":"21","key":"10.1016\/j.molimm.2015.06.026_bib0280","doi-asserted-by":"crossref","first-page":"5175","DOI":"10.1046\/j.1432-1033.2002.03215.x","article-title":"The analysis of the fine specificity of celiac disease antibodies using tissue transglutaminase fragments","volume":"269","author":"Sblattero","year":"2002","journal-title":"Eur. J. Biochem."},{"issue":"7","key":"10.1016\/j.molimm.2015.06.026_bib0285","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.autrev.2010.02.006","article-title":"Wegener\u2019s granulomatosis vasculitis and granuloma","volume":"9","author":"Schilder","year":"2010","journal-title":"Autoimmun. Rev."},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0290","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.0300-9475.2005.01549.x","article-title":"Immunoglobulin isotype profile of tissue transglutaminase autoantibodies is correlated with the clinical presentation of coeliac disease","volume":"61","author":"Schilling","year":"2005","journal-title":"Scand. J. Immunol."},{"issue":"5","key":"10.1016\/j.molimm.2015.06.026_bib0295","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1007\/s00125-005-1719-1","article-title":"Dynamic changes of GAD65 autoantibody epitope specificities in individuals at risk of developing type 1 diabetes","volume":"48","author":"Schlosser","year":"2005","journal-title":"Diabetologia"},{"key":"10.1016\/j.molimm.2015.06.026_bib0300","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/gut.40.4.481","article-title":"Pancreatic autoantibodies in Crohn\u2019s disease: a family study","author":"Seibold","year":"1997","journal-title":"Gut"},{"key":"10.1016\/j.molimm.2015.06.026_bib0305","series-title":"Autoantibodies","author":"Shoenfeld","year":"2007"},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0310","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1073\/pnas.1107811108","article-title":"A single conformational transglutaminase 2 epitope contributed by three domains is critical for celiac antibody binding and effects","volume":"109","author":"Simon-Vecsei","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.molimm.2015.06.026_bib0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00403-007-0734-0","article-title":"The relevance of the IgG subclass of autoantibodies for blister induction in autoimmune bullous skin diseases","volume":"299","author":"Sitaru","year":"2007","journal-title":"Arch. Dermatol. Res."},{"issue":"5","key":"10.1016\/j.molimm.2015.06.026_bib0320","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1080\/73-0891693021000005402","article-title":"Factor XIII and tissue transglutaminase antibodies in coeliac and inflammatory bowel disease","volume":"35","author":"Sjoberg","year":"2002","journal-title":"Autoimmunity"},{"issue":"3\u20134","key":"10.1016\/j.molimm.2015.06.026_bib0325","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/BF00351165","article-title":"Clinical and immunological aspects of autoantibodies to RA33\/hnRNP-A\/B proteins-a link between RA, SLE and MCTD","volume":"23","author":"Steiner","year":"1996","journal-title":"Mol. Biol. Rep."},{"issue":"6","key":"10.1016\/j.molimm.2015.06.026_bib0330","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1097\/MOG.0b013e32830e6d98","article-title":"Leaking gut in type 1 diabetes","volume":"24","author":"Vaarala","year":"2008","journal-title":"Curr. Opin. Gastroenterol."},{"issue":"4","key":"10.1016\/j.molimm.2015.06.026_bib0335","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1136\/gut.47.4.487","article-title":"Marker antibody expression stratifies Crohn\u2019s disease into immunologically homogeneous subgroups with distinct clinical characteristics","volume":"47","author":"Vasiliauskas","year":"2000","journal-title":"Gut"},{"issue":"7","key":"10.1016\/j.molimm.2015.06.026_bib0340","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1093\/clinchem\/48.7.1133","article-title":"IgG anti-transglutaminase autoantibodies in systemic lupus erythematosus and Sjogren syndrome","volume":"48","author":"Villalta","year":"2002","journal-title":"Clin. Chem."},{"issue":"4","key":"10.1016\/j.molimm.2015.06.026_bib0345","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1159\/000324456","article-title":"Lower expression of tight junction protein 1 gene and increased FOXP3 expression in the small bowel mucosa in coeliac disease and associated type 1 diabetes mellitus","volume":"156","author":"Vorobjova","year":"2011","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.molimm.2015.06.026_bib0350","article-title":"TG2, a novel extracellular protein with multiple functions","author":"Wang","year":"2011","journal-title":"Amino Acids"},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0355","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1038\/sj.leu.2403539","article-title":"Th1-biased humoral immune responses against Wilms tumor gene WT1 product in the patients with hematopoietic malignancies","volume":"19","author":"Wu","year":"2005","journal-title":"Leukemia"},{"issue":"2","key":"10.1016\/j.molimm.2015.06.026_bib0360","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1365-2249.2008.03756.x","article-title":"Distribution of immunoglobulin G subclasses of anti-thyroid peroxidase antibody in sera from patients with Hashimoto\u2019s thyroiditis with different thyroid functional status","volume":"154","author":"Xie","year":"2008","journal-title":"Clin. Exp. Immunol."}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589015300043?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589015300043?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,12]],"date-time":"2023-08-12T06:05:15Z","timestamp":1691820315000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589015300043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":72,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S0161589015300043"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2015.06.026","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"IgG anti-tTG responses in different autoimmune conditions differ in their epitope targets and subclass usage","name":"articletitle","label":"Article Title"},{"value":"Molecular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molimm.2015.06.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}