{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T10:32:51Z","timestamp":1789813971477,"version":"4.0.1"},"reference-count":68,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.molimm.2015.07.041","type":"journal-article","created":{"date-parts":[[2015,8,29]],"date-time":"2015-08-29T04:50:40Z","timestamp":1440823840000},"page":"625-635","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"PB","title":["Peptide motif analysis predicts lymphocytic choriomeningitis virus as trigger for multiple sclerosis"],"prefix":"10.1016","volume":"67","author":[{"given":"Charissa","family":"Hogeboom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.molimm.2015.07.041_bib0005","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1001\/jama.1975.03250050016009","article-title":"Lymphocytic choriomeningitis outbreak associated with pet hamsters. Fifty-seven cases from New York State","volume":"232","author":"Biggar","year":"1975","journal-title":"JAMA"},{"key":"10.1016\/j.molimm.2015.07.041_bib0010","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/ana.21161","article-title":"Congenital lymphocytic choriomeningitis virus infection: spectrum of disease","volume":"62","author":"Bonthius","year":"2007","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.molimm.2015.07.041_bib0015","article-title":"Type I IFN and TNF\u03b1 cross-regulation in immune-mediated inflammatory disease: basic concepts and clinical relevance","volume":"219","author":"Cantaert","year":"2010","journal-title":"Arthritis Res. Ther. 12"},{"key":"10.1016\/j.molimm.2015.07.041_bib0020","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1186\/s12974-014-0188-1","article-title":"Epstein\u2013Barr virus-specific intrathecal oligoclonal IgG production in relapsing-remitting multiple sclerosis is limited to a subset of patients and is composed of low-affinity antibodies","volume":"11","author":"Castellazi","year":"2014","journal-title":"J. Neuroinflammation"},{"issue":"3\u20134","key":"10.1016\/j.molimm.2015.07.041_bib0025","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.vetmic.2009.08.027","article-title":"Zoonotic aspects of arenavirus infections","volume":"140","author":"Charrel","year":"2010","journal-title":"Vet. Microbiol."},{"issue":"1","key":"10.1016\/j.molimm.2015.07.041_bib0030","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4269\/ajtmh.1992.47.27","article-title":"Lymphocytic choriomeningitis virus infection and house mouse (Mus musculus) distribution in urban Baltimore","volume":"47","author":"Childs","year":"1992","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"11","key":"10.1016\/j.molimm.2015.07.041_bib0035","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1177\/1352458511408754","article-title":"Epidemiology of multiple sclerosis in south-western Sardinia","volume":"17","author":"Cocco","year":"2011","journal-title":"Mult. Scler."},{"key":"10.1016\/j.molimm.2015.07.041_bib0040","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1093\/brain\/awp228","article-title":"A type I interferon signature in monocytes is associated with poor response to interferon-\u03b2 in multiple sclerosis","volume":"132","author":"Comabella","year":"2009","journal-title":"Brain"},{"issue":"4","key":"10.1016\/j.molimm.2015.07.041_bib0045","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1097\/BOR.0b013e328362004d","article-title":"Multiple sclerosis: autoimmunity and viruses","volume":"25","author":"Cusick","year":"2013","journal-title":"Curr. Opin. Rheumatol."},{"issue":"12","key":"10.1016\/j.molimm.2015.07.041_bib0050","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1002\/jmv.20749","article-title":"High prevalence of antibodies to lymphocytic choriomeningitis virus in a murine typhus endemic region in Croatia","volume":"78","author":"Dobec","year":"2006","journal-title":"J. Med. Virol."},{"issue":"Suppl 1","key":"10.1016\/j.molimm.2015.07.041_bib0055","doi-asserted-by":"crossref","DOI":"10.1186\/1756-3305-7-S1-O31","article-title":"Increased seroprevalence of lymphocytic choriomeningitis virus infection in mice sampled in illegal waste sites","volume":"7","author":"Duh","year":"2014","journal-title":"Parasites Vectors"},{"key":"10.1016\/j.molimm.2015.07.041_bib0060","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1073\/pnas.81.1.140","article-title":"The hydrophobic moment detects periodicity in protein hydrophobicity","volume":"81","author":"Eisenberg","year":"1984","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"3","key":"10.1016\/j.molimm.2015.07.041_bib0065","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1006\/jaut.2000.0484","article-title":"Can virus infections trigger autoimmune disease?","volume":"16","author":"Fujinami","year":"2001","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.molimm.2015.07.041_bib0070","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1600-065X.2012.01134.x","article-title":"The genetics of multiple sclerosis: an up-to-date review","volume":"248","author":"Gourraud","year":"2012","journal-title":"Immunol. Rev."},{"issue":"12","key":"10.1016\/j.molimm.2015.07.041_bib0075","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1007\/s00415-007-0560-5","article-title":"Multiple sclerosis in the province of Ferrara: evidence for an increasing trend","volume":"254","author":"Granieri","year":"2007","journal-title":"J. Neurol."},{"issue":"1","key":"10.1016\/j.molimm.2015.07.041_bib0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/brain\/111.1.1","article-title":"The epidemiology of multiple sclerosis in three Australian cities: Perth, Newcastle and Hobart","volume":"111","author":"Hammond","year":"1988","journal-title":"Brain"},{"key":"10.1016\/j.molimm.2015.07.041_bib0085","doi-asserted-by":"crossref","first-page":"334","DOI":"10.4049\/jimmunol.162.1.338","article-title":"Structural features of autoreactive TCR that determine the degree of degeneracy in peptide recognition","volume":"162","author":"Hausmann","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2015.07.041_bib0090","doi-asserted-by":"crossref","first-page":"10915","DOI":"10.1073\/pnas.89.22.10915","article-title":"Amino acid substitution matrices from protein blocks","volume":"89","author":"Henikoff","year":"1992","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.molimm.2015.07.041_bib0095","series-title":"Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis","article-title":"The epidemiology of EBV and its association with malignant disease","author":"Hjalgrim","year":"2007"},{"key":"10.1016\/j.molimm.2015.07.041_bib0100","unstructured":"Hornik K., 2014. The R FAQ. http:\/\/cran.r-project.org\/doc\/FAQ\/R-FAQ.html#Citing-this-document (accessed 10.11.14.)."},{"key":"10.1016\/j.molimm.2015.07.041_bib0105","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/ana.20871","article-title":"Differential twin concordance for multiple sclerosis by latitude of birthplace","volume":"60","author":"Islam","year":"2006","journal-title":"Ann. Neurol."},{"issue":"13","key":"10.1016\/j.molimm.2015.07.041_bib0110","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1056\/NEJM200009283431301","article-title":"Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group","volume":"343","author":"Jacobs","year":"2000","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.molimm.2015.07.041_bib0115","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0022-2836(78)90408-4","article-title":"Conformation of amino acid side-chains in proteins","volume":"125","author":"Janin","year":"1978","journal-title":"J. Mol. Biol."},{"issue":"5","key":"10.1016\/j.molimm.2015.07.041_bib0120","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1006\/cyto.2001.0884","article-title":"IFN-\u03b2 inhibits the ability of T lymphocytes to induce TNF-\u03b1 and IL-1\u03b2 production in monocytes upon direct cell-cell contact","volume":"14","author":"Jungo","year":"2001","journal-title":"Cytokine"},{"key":"10.1016\/j.molimm.2015.07.041_bib0125","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.bbadis.2010.06.012","article-title":"Viral triggers of multiple sclerosis","volume":"1812","author":"Kakalacheva","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.molimm.2015.07.041_bib0130","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1007\/BF01195768","article-title":"Prediction of chain flexibility in proteins\u2014a tool for the selection of peptide antigens","volume":"72","author":"Karplus","year":"1985","journal-title":"Naturwissenschafren"},{"key":"10.1016\/j.molimm.2015.07.041_bib0135","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1111\/j.1468-1331.2008.02262.x","article-title":"Concordance and heritability of multiple sclerosis in Finland: study on a nationwide series of twins","volume":"15","author":"Kuusisto","year":"2008","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.molimm.2015.07.041_bib0140","series-title":"Lymphocytic choriomeningitis virus","author":"Lehmann-Grube","year":"1971"},{"key":"10.1016\/j.molimm.2015.07.041_bib0145","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1006\/jmbi.2000.4198","article-title":"Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins","volume":"304","author":"Li","year":"2000","journal-title":"J. Mol. Biol."},{"issue":"5","key":"10.1016\/j.molimm.2015.07.041_bib0150","doi-asserted-by":"crossref","first-page":"e36779","DOI":"10.1371\/journal.pone.0036779","article-title":"Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis","volume":"7","author":"Link","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.molimm.2015.07.041_bib0155","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1084\/jem.182.5.1517","article-title":"Interferon (IFN) \u03b2 acts downstream of IFN-\u03b3-induced class II transactivator messenger RNA accumulation to block major histocompatibility complex class II gene expression and requires the 48-kD DNA-binding protein, ISGF3-\u03b3","volume":"182","author":"Lu","year":"1995","journal-title":"J. Exp. Med."},{"issue":"8","key":"10.1016\/j.molimm.2015.07.041_bib0160","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1084\/jem.20072397","article-title":"EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-\u03b3 and IL-2","volume":"205","author":"L\u00fcnemann","year":"2008","journal-title":"J. Exp. Med."},{"issue":"21","key":"10.1016\/j.molimm.2015.07.041_bib0165","doi-asserted-by":"crossref","first-page":"11330","DOI":"10.1128\/JVI.00763-09","article-title":"Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus","volume":"83","author":"Mart\u00ednez-Sobrido","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.molimm.2015.07.041_bib0170","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S0303-8467(02)00037-9","article-title":"Epidemiology of multiple sclerosis in Croatia","volume":"104","author":"Materljan","year":"2002","journal-title":"Clin. Neurol. Neurosurg."},{"key":"10.1016\/j.molimm.2015.07.041_bib0175","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1007\/s00415-010-5898-4","article-title":"Migration and multiple sclerosis in immigrants to Australia from United Kingdom and Ireland: a reassessment. I. Risk of MS by age at immigration","volume":"258","author":"McLeod","year":"2011","journal-title":"J. Neurol."},{"issue":"10","key":"10.1016\/j.molimm.2015.07.041_bib0180","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1136\/jnnp.53.10.903","article-title":"Multiple sclerosis in Australia and New Zealand: are the determinants genetic or environmental?","volume":"53","author":"Miller","year":"1990","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"1","key":"10.1016\/j.molimm.2015.07.041_bib0185","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1212\/WNL.44.1.11","article-title":"The British Isles survey of multiple sclerosis in twins","volume":"44","author":"Mumford","year":"1994","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/j.molimm.2015.07.041_bib0190","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1212\/WNL.0b013e318263c407","article-title":"Contributions of vitamin D response elements and HLA promoters to multiple sclerosis risk","volume":"79","author":"Nolan","year":"2012","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.molimm.2015.07.041_bib0195","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1172\/JCI200113032","article-title":"A virus-induced molecular mimicry model of multiple sclerosis","volume":"108","author":"Olson","year":"2001","journal-title":"J. Clin. Invest."},{"issue":"24","key":"10.1016\/j.molimm.2015.07.041_bib0200","doi-asserted-by":"crossref","first-page":"13038","DOI":"10.1128\/JVI.05834-11","article-title":"The C-terminal region of lymphocytic choriomeningitis virus nucleoprotein contains distinct and segregable functional domains involved in NP-Z interaction and counteraction of the type I interferon response","volume":"85","author":"Ortiz-Ria\u00f1o","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.molimm.2015.07.041_bib0205","doi-asserted-by":"crossref","first-page":"5425","DOI":"10.1021\/bi00367a013","article-title":"New hydrophilicity scale derived from high-performance liquid chromatography peptide retention data: correlation of predicted surface residues with antigenicity and X-ray-derived accessible sites","volume":"25","author":"Parker","year":"1986","journal-title":"Biochem"},{"issue":"Suppl 2","key":"10.1016\/j.molimm.2015.07.041_bib0210","first-page":"141","article-title":"The town of Cabar, Croatia, familiar pseudocluster for multiple sclerosis\u2014descriptive epidemiological study","volume":"34","author":"Percovi\u0107","year":"2010","journal-title":"Coll. Antropol."},{"key":"10.1016\/j.molimm.2015.07.041_bib0215","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jns.2006.04.002","article-title":"Region with persistent high frequency of multiple sclerosis in Croatia and Slovenia","volume":"247","author":"Peterlin","year":"2006","journal-title":"J. Neurol. Sci."},{"issue":"15","key":"10.1016\/j.molimm.2015.07.041_bib0220","doi-asserted-by":"crossref","first-page":"7728","DOI":"10.1128\/JVI.00187-12","article-title":"Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKK\u03f5","volume":"86","author":"Pythoud","year":"2012","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.molimm.2015.07.041_bib0225","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1177\/1352458510391345","article-title":"HLA-DR allele polymorphism and multiple sclerosis in Chinese populations: a meta-analysis","volume":"17","author":"Qiu","year":"2011","journal-title":"Mult. Scler."},{"key":"10.1016\/j.molimm.2015.07.041_bib0230","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1006\/viro.1999.9638","article-title":"Identification of MaTu-MX agent as a new strain of lymphocytic choriomeningitis virus (LCMV) and serological indication of horizontal spread of LCMV in human population","volume":"257","author":"Reiserov\u00e1","year":"1999","journal-title":"Virol"},{"issue":"1","key":"10.1016\/j.molimm.2015.07.041_bib0235","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/ana.20683","article-title":"Multiple sclerosis in twins from continental Italy and Sardinia: a nationwide study","volume":"59","author":"Ristori","year":"2006","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.molimm.2015.07.041_bib0240","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/ana.410330309","article-title":"A population-based study of multiple sclerosis in twins: update","volume":"33","author":"Sadovnick","year":"1993","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.molimm.2015.07.041_bib0245","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1124\/pr.114.009639","article-title":"Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases","volume":"67","author":"Siebert","year":"2015","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.molimm.2015.07.041_bib0250","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1136\/jnnp.2011.240432","article-title":"Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis","volume":"82","author":"Simpson","year":"2011","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"7","key":"10.1016\/j.molimm.2015.07.041_bib0255","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.humimm.2008.05.001","article-title":"Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta-analytic review of 497 population studies","volume":"69","author":"Solberg","year":"2008","journal-title":"Hum. Immunol."},{"issue":"2","key":"10.1016\/j.molimm.2015.07.041_bib0260","doi-asserted-by":"crossref","first-page":"219","DOI":"10.7589\/0090-3558-29.2.219","article-title":"A serological survey for viruses and Mycoplasma pulmonis among wild house mice (Mus domesticus) in southeastern Australia","volume":"29","author":"Smith","year":"1993","journal-title":"J. Wildl. Dis."},{"issue":"8","key":"10.1016\/j.molimm.2015.07.041_bib0265","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1084\/jem.188.8.1511","article-title":"Crystal structure of HLA-DR2 (DRA1*1010. DRB1*1501) complexed with a peptide from human myelin basic protein","volume":"188","author":"Smith","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.molimm.2015.07.041_bib0270","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/368215a0","article-title":"Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide","volume":"368","author":"Stern","year":"1994","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.molimm.2015.07.041_bib0275","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.3201\/eid1507.01524","article-title":"Spatial and temporal dynamics of lymphocytic choriomeningitis virus in wild rodents, northern Italy","volume":"15","author":"Tagliapietra","year":"2009","journal-title":"Emerg. Infect. Dis."},{"issue":"8","key":"10.1016\/j.molimm.2015.07.041_bib0280","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/S0198-8859(99)00033-6","article-title":"The DRB1 Val86\/Val86 genotype associates with multiple sclerosis in Australian patients","volume":"60","author":"Teutsch","year":"1999","journal-title":"Hum. Immunol."},{"issue":"2","key":"10.1016\/j.molimm.2015.07.041_bib0285","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1084\/jem.68.2.229","article-title":"Factors influencing the persistence of choriomeningitis virus in the blood of mice after clinical recovery","volume":"68","author":"Traub","year":"1938","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.molimm.2015.07.041_bib0290","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/sj.gene.6364324","article-title":"A subtype of multiple sclerosis defined by an activated immune defense program","volume":"7","author":"van Baarsen","year":"2006","journal-title":"Genes Immun."},{"issue":"4","key":"10.1016\/j.molimm.2015.07.041_bib0295","doi-asserted-by":"crossref","first-page":"e1927","DOI":"10.1371\/journal.pone.0001927","article-title":"Pharmacogenomics of interferon-\u03b2 therapy in multiple sclerosis: baseline IFN signature determines pharmacological differences between patients","volume":"3","author":"van Baarsen","year":"2008","journal-title":"PLoS One"},{"issue":"12","key":"10.1016\/j.molimm.2015.07.041_bib0300","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1136\/ard.2005.040477","article-title":"Expression of interferon \u03b2 in synovial tissue from patients with rheumatoid arthritis: comparison with patients with osteoarthritis and reactive arthritis","volume":"64","author":"van Holten","year":"2005","journal-title":"Ann. Rheum. Dis."},{"issue":"1","key":"10.1016\/j.molimm.2015.07.041_bib0305","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1136\/ard.2003.020347","article-title":"A multicentre, randomised, double blind, placebo controlled phase II study of subcutaneous interferon beta-1a in the treatment of patients with active rheumatoid arthritis","volume":"64","author":"van Holten","year":"2005","journal-title":"Ann. Rheum. Dis."},{"issue":"7","key":"10.1016\/j.molimm.2015.07.041_bib0310","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1136\/jnnp-2011-301546","article-title":"A new prevalence study of multiple sclerosis in Orkney, Shetland and Aberdeen city","volume":"83","author":"Visser","year":"2012","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"issue":"2","key":"10.1016\/j.molimm.2015.07.041_bib0315","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0014-5793(85)80374-4","article-title":"Prediction of sequential antigenic regions in proteins","volume":"188","author":"Welling","year":"1985","journal-title":"FEBS Lett."},{"issue":"22","key":"10.1016\/j.molimm.2015.07.041_bib0320","doi-asserted-by":"crossref","first-page":"12877","DOI":"10.1073\/pnas.1932604100","article-title":"Twin concordance and sibling recurrence rates in multiple sclerosis","volume":"100","author":"Willer","year":"2003","journal-title":"PNAS"},{"key":"10.1016\/j.molimm.2015.07.041_bib0325","series-title":"Atlas: Multiple Sclerosis Resources in the World 2008","author":"World Health Organization","year":"2008"},{"issue":"5","key":"10.1016\/j.molimm.2015.07.041_bib0330","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1177\/1352458510362997","article-title":"Influence of HLA-DRB1 allele heterogeneity on disease risk and clinical course in a West Australian MS cohort: a high-resolution genotyping study","volume":"16","author":"Wu","year":"2010","journal-title":"Mult. Scler."},{"issue":"2","key":"10.1016\/j.molimm.2015.07.041_bib0335","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.smim.2011.01.007","article-title":"T cell receptor recognition of self and foreign antigens in the induction of autoimmunity","volume":"23","author":"Wucherpfennig","year":"2011","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.molimm.2015.07.041_bib0340","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1084\/jem.179.1.279","article-title":"Structural requirements for binding of an immunodominant myelin basic protein to DR2 isotypes and for its recognition by human T cell clones","volume":"179","author":"Wucherpfennig","year":"1994","journal-title":"J. Exp. Med."}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589015300493?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589015300493?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,13]],"date-time":"2023-08-13T14:45:35Z","timestamp":1691937935000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589015300493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":68,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S0161589015300493"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2015.07.041","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Peptide motif analysis predicts lymphocytic choriomeningitis virus as trigger for multiple sclerosis","name":"articletitle","label":"Article Title"},{"value":"Molecular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molimm.2015.07.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}