{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:21:57Z","timestamp":1772986917553,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T00:00:00Z","timestamp":1544054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000854","name":"Human Frontier Science Program","doi-asserted-by":"publisher","award":["RGP0016\/2009-C"],"award-info":[{"award-number":["RGP0016\/2009-C"]}],"id":[{"id":"10.13039\/501100000854","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.molimm.2018.12.003","type":"journal-article","created":{"date-parts":[[2018,12,15]],"date-time":"2018-12-15T09:57:06Z","timestamp":1544867826000},"page":"260-269","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Antifungal activities of surfactant protein D in an environment closely mimicking the lung lining"],"prefix":"10.1016","volume":"105","author":[{"given":"Soledad R.","family":"Ordonez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"van Eijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Escobar Salazar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"de Cock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin J.A.","family":"Veldhuizen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4931-5201","authenticated-orcid":false,"given":"Henk P.","family":"Haagsman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"April (4)","key":"10.1016\/j.molimm.2018.12.003_bib0005","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1128\/IAI.69.4.2037-2044.2001","article-title":"Interactions of surfactant proteins A and D with Saccharomyces cerevisiae and Aspergillus fumigatus","volume":"69","author":"Allen","year":"2001","journal-title":"Infect. Immun."},{"issue":"July","key":"10.1016\/j.molimm.2018.12.003_bib0010","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.biocel.2014.02.009","article-title":"Effects of airway surface liquid pH on host defense in cystic fibrosis","volume":"52","author":"Berkebile","year":"2014","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"January (1)","key":"10.1016\/j.molimm.2018.12.003_bib0015","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/intimm\/dxh356","article-title":"Aspergillus fumigatus conidia inhibit tumour necrosis factor- or staurosporine-induced apoptosis in epithelial cells","volume":"18","author":"Berkova","year":"2006","journal-title":"Int. Immunol."},{"issue":"February (1)","key":"10.1016\/j.molimm.2018.12.003_bib0020","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3109\/13693780903117473","article-title":"Collectins and fungal pathogens: roles of surfactant proteins and mannose binding lectin in host resistance","volume":"48","author":"Brummer","year":"2010","journal-title":"Med. Mycol."},{"issue":"November (5)","key":"10.1016\/j.molimm.2018.12.003_bib0025","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1183\/09031936.00.16583100","article-title":"Increased levels of surfactant protein A and D in bronchoalveolar lavage fluids in patients with bronchial asthma","volume":"16","author":"Cheng","year":"2000","journal-title":"Eur. Respir. J."},{"issue":"2","key":"10.1016\/j.molimm.2018.12.003_bib0030","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1165\/ajrcmb.19.2.140","article-title":"Collectins and pulmonary host defense","volume":"19","author":"Crouch","year":"1998","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"December (12)","key":"10.1016\/j.molimm.2018.12.003_bib0035","doi-asserted-by":"crossref","first-page":"6514","DOI":"10.1128\/IAI.01551-06","article-title":"Role of neutrophils in invasive aspergillosis","volume":"74","author":"Feldmesser","year":"2006","journal-title":"Infect. Immun."},{"issue":"December (2)","key":"10.1016\/j.molimm.2018.12.003_bib0040","first-page":"248","article-title":"Fungal surface and innate immune recognition of filamentous fungi","volume":"19","author":"Figueiredo","year":"2011","journal-title":"Front. Microbiol."},{"issue":"July (7)","key":"10.1016\/j.molimm.2018.12.003_bib0045","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1007\/s11095-006-0255-0","article-title":"Culture of Calu-3 cells at the air interface provides a representative model of the airway epithelial barrier","volume":"23","author":"Grainger","year":"2006","journal-title":"Pharm. Res."},{"issue":"May (1)","key":"10.1016\/j.molimm.2018.12.003_bib0050","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S1095-6433(01)00308-7","article-title":"Surfactant-associated proteins: functions and structural variation","volume":"129","author":"Haagsman","year":"2001","journal-title":"Comp. Biochem. Physiol. A Mol. Integr. Physiol."},{"issue":"July (13)","key":"10.1016\/j.molimm.2018.12.003_bib0055","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.1016\/j.molimm.2007.02.025","article-title":"Expression sites of the collectin SP-D suggest its importance in first line host defence: power of combining in situ hybridisation, RT-PCR and immunohistochemistry","volume":"44","author":"Herias","year":"2007","journal-title":"Mol. Immunol."},{"issue":"February (3)","key":"10.1016\/j.molimm.2018.12.003_bib0060","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1172\/JCI11154","article-title":"Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH","volume":"107","author":"Jayaraman","year":"2001","journal-title":"J. Clin. Invest."},{"issue":"October (2)","key":"10.1016\/j.molimm.2018.12.003_bib0065","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1365-2958.2007.05872.x","article-title":"The cell wall: a carbohydrate armour for the fungal cell","volume":"66","author":"Latge","year":"2007","journal-title":"Mol. Microbiol."},{"issue":"276","key":"10.1016\/j.molimm.2018.12.003_bib0070","first-page":"90","article-title":"Defensins: endogenous antibiotic peptides from human leukocytes","volume":"171","author":"Lehrer","year":"1992","journal-title":"Ciba Found. Symp."},{"issue":"August (8)","key":"10.1016\/j.molimm.2018.12.003_bib0075","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.1128\/IAI.65.8.3171-3179.1997","article-title":"Binding of pulmonary surfactant proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages","volume":"65","author":"Madan","year":"1997","journal-title":"Infect. Immun."},{"issue":"June (11)","key":"10.1016\/j.molimm.2018.12.003_bib0080","doi-asserted-by":"crossref","first-page":"5866","DOI":"10.4049\/jimmunol.164.11.5866","article-title":"Localization of lung surfactant protein D on mucosal surfaces in human tissues","volume":"164","author":"Madsen","year":"2000","journal-title":"J. Immunol."},{"issue":"May (5)","key":"10.1016\/j.molimm.2018.12.003_bib0085","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/j.1469-0691.2006.01388.x","article-title":"Role of the dual interaction of fungal pathogens with pattern recognition receptors in the activation and modulation of host defence","volume":"12","author":"Netea","year":"2006","journal-title":"Clin. Microbiol. Infect."},{"issue":"January (1)","key":"10.1016\/j.molimm.2018.12.003_bib0090","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/nrmicro1815","article-title":"An integrated model of the recognition of Candida albicans by the innate immune system","volume":"6","author":"Netea","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"issue":"5","key":"10.1016\/j.molimm.2018.12.003_bib0095","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s00408-004-2511-6","article-title":"Innate host defense of the lung: effects of lung-lining fluid pH","volume":"182","author":"Ng","year":"2004","journal-title":"Lung"},{"issue":"July (1)","key":"10.1016\/j.molimm.2018.12.003_bib0100","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1189\/jlb.3AB0213-092RR","article-title":"Leukocyte-associated Ig-like receptor-1 is a novel inhibitory receptor for surfactant protein D","volume":"96","author":"Olde Nordkamp","year":"2014","journal-title":"J. Leukoc. Biol."},{"issue":"March (3)","key":"10.1016\/j.molimm.2018.12.003_bib0105","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1128\/AEM.69.3.1581-1588.2003","article-title":"Conidial hydrophobins of Aspergillus fumigatus","volume":"69","author":"Paris","year":"2003","journal-title":"Appl. Environ. Microbiol."},{"issue":"November (Suppl 1)","key":"10.1016\/j.molimm.2018.12.003_bib0110","doi-asserted-by":"crossref","first-page":"S22","DOI":"10.3109\/13693786.2010.511286","article-title":"Local innate host response and filamentous fungi in patients with cystic fibrosis","volume":"48","author":"Roilides","year":"2010","journal-title":"Med. Mycol."},{"issue":"September","key":"10.1016\/j.molimm.2018.12.003_bib0115","first-page":"11","article-title":"Fungal infections in AIDS patients","volume":"71","author":"Stevens","year":"1990","journal-title":"Br. J. Clin. Pract. Suppl."},{"issue":"August (32)","key":"10.1016\/j.molimm.2018.12.003_bib0120","doi-asserted-by":"crossref","first-page":"26666","DOI":"10.1074\/jbc.M112.368571","article-title":"A unique sugar-binding site mediates the distinct anti-influenza activity of pig surfactant protein D","volume":"287","author":"van Eijk","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"June (23)","key":"10.1016\/j.molimm.2018.12.003_bib0125","doi-asserted-by":"crossref","first-page":"20137","DOI":"10.1074\/jbc.M111.224469","article-title":"Introduction of N-linked glycans in the lectin domain of surfactant protein D: impact on interactions with influenza A viruses","volume":"286","author":"van Eijk","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"September (3)","key":"10.1016\/j.molimm.2018.12.003_bib0130","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1086\/315799","article-title":"Role of pulmonary surfactant protein D in innate defense against Candida albicans","volume":"182","author":"van Rozendaal","year":"2000","journal-title":"J. Infect. Dis."},{"issue":"July\u2013August (4)","key":"10.1016\/j.molimm.2018.12.003_bib0135","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1080\/15513810109168824","article-title":"Localization and functions of SP-A and SP-D at mucosal surfaces","volume":"20","author":"van Rozendaal","year":"2001","journal-title":"Pediatr. Pathol. Mol. Med."},{"issue":"December (4)","key":"10.1016\/j.molimm.2018.12.003_bib0140","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1034\/j.1399-3062.1999.010404.x","article-title":"Emerging fungal pathogens: evolving challenges to immunocompromised patients for the twenty-first century","volume":"1","author":"Walsh","year":"1999","journal-title":"Transpl. Infect. Dis."},{"issue":"June (6)","key":"10.1016\/j.molimm.2018.12.003_bib0145","doi-asserted-by":"crossref","first-page":"3156","DOI":"10.1128\/IAI.70.6.3156-3163.2002","article-title":"Uptake of Aspergillus fumigatus Conidia by phagocytic and nonphagocytic cells in vitro: quantitation using strains expressing green fluorescent protein","volume":"70","author":"Wasylnka","year":"2002","journal-title":"Infect. Immun."},{"issue":"August (2)","key":"10.1016\/j.molimm.2018.12.003_bib0150","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1093\/toxsci\/68.2.488","article-title":"The role of interleukin-6 in pulmonary inflammation and injury induced by exposure to environmental air pollutants","volume":"68","author":"Yu","year":"2002","journal-title":"Toxicol. Sci."}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589018310058?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589018310058?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T22:40:57Z","timestamp":1605652857000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589018310058"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":30,"alternative-id":["S0161589018310058"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2018.12.003","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antifungal activities of surfactant protein D in an environment closely mimicking the lung lining","name":"articletitle","label":"Article Title"},{"value":"Molecular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molimm.2018.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}