{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T05:56:53Z","timestamp":1777787813162,"version":"3.51.4"},"reference-count":117,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100018316","name":"Institute of Chemical Biology, National Hellenic Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018316","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["168270\/2017\\u20130"],"award-info":[{"award-number":["168270\/2017\\u20130"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["308344\/2016\\u20132"],"award-info":[{"award-number":["308344\/2016\\u20132"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007374","name":"Universidade Federal de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007374","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.molimm.2023.02.010","type":"journal-article","created":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T17:10:55Z","timestamp":1678122655000},"page":"61-76","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["MCP-1\/IL-12 ratio expressions correlated with adventitial collagen depositions in renal vessels and IL-4\/IFN-\u03b3 expression correlated with interstitial collagen depositions in the kidneys of dogs with canine leishmaniasis"],"prefix":"10.1016","volume":"156","author":[{"given":"Barbara Laurice Ara\u00fajo","family":"Ver\u00e7osa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Imaculada","family":"Muniz-Junqueira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Menezes-Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo Toshio","family":"Fujiwara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciano de F.","family":"Borges","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Norma","family":"Melo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anilton Cesar","family":"Vasconcelos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.molimm.2023.02.010_bib1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/jlb.63.1.108","article-title":"Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model","volume":"63","author":"Ajuebor","year":"1998","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.molimm.2023.02.010_bib2","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1159\/000368940","article-title":"Update on inflammation in chronic kidney disease","volume":"39","author":"Akchurin","year":"2015","journal-title":"Blood Purif."},{"key":"10.1016\/j.molimm.2023.02.010_bib3","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.vetimm.2008.11.020","article-title":"Expression of IFN-gamma, TNF-alpha, IL-10 and TGF-beta in lymph nodes associates with parasite load and clinical form of disease in dogs naturally infected with Leishmania (Leishmania) chagasi","volume":"128","author":"Alves","year":"2009","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.molimm.2023.02.010_bib4","doi-asserted-by":"crossref","first-page":"398","DOI":"10.4049\/jimmunol.172.1.398","article-title":"Essential contribution of monocyte chemoattractant protein-1\/C-C chemokine ligand-2 to resolution and repair processes in acute bacterial pneumonia","volume":"172","author":"Amano","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib5","doi-asserted-by":"crossref","first-page":"5658","DOI":"10.4049\/jimmunol.170.11.5658","article-title":"CC chemokine ligand 5\/RANTES chemokine antagonists aggravate glomerulonephritis despite reduction of glomerular leukocyte infiltration","volume":"170","author":"Anders","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib6","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.3389\/fphar.2019.01192","article-title":"Inflammation in renal diseases: new and old players","volume":"10","author":"Andrade-Oliveira","year":"2019","journal-title":"Front Pharm."},{"key":"10.1016\/j.molimm.2023.02.010_bib7","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0040-8166(98)80014-1","article-title":"Continuous sub-endothelial network formed by pericyte-like cells in human vascular bed","volume":"30","author":"Andreeva","year":"1998","journal-title":"Tissue Cell"},{"key":"10.1016\/j.molimm.2023.02.010_bib8","doi-asserted-by":"crossref","first-page":"4339","DOI":"10.1093\/ndt\/gfs256","article-title":"Cytokine production increases and cytokine clearance decreases in mice with bilateral nephrectomy","volume":"27","author":"Andres-Hernando","year":"2012","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.molimm.2023.02.010_bib9","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s00467-006-0026-5","article-title":"A case of unfulfilled expectations: cytokines in idiopathic minimal lesion nephrotic syndrome","volume":"21","author":"Araya","year":"2006","journal-title":"Pediatr. Nephrol."},{"key":"10.1016\/j.molimm.2023.02.010_bib10","first-page":"1515","article-title":"Interleukin-12 restores interferon-gamma production and cytotoxic responses in visceral Leishmaniosis. J. Infect","volume":"173","author":"Bacellar","year":"1996","journal-title":"Dis"},{"key":"10.1016\/j.molimm.2023.02.010_bib11","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1006\/cyto.2000.0694","article-title":"IL-10 and IL-12 are the main regulatory cytokines in visceral Leishmaniosis","volume":"12","author":"Bacellar","year":"2000","journal-title":"Cytokine"},{"key":"10.1016\/j.molimm.2023.02.010_bib12","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1053\/ajkd.2001.20734","article-title":"How renal cytokines and growth factors contribute to renal disease progression","volume":"37","author":"Benigni","year":"2001","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.molimm.2023.02.010_bib13","doi-asserted-by":"crossref","first-page":"L785","DOI":"10.1152\/ajplung.00336.2002","article-title":"Magnitude-dependent regulation of pulmonary endothelial cell barrier function by cyclic stretch","volume":"285","author":"Birukov","year":"2003","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.molimm.2023.02.010_bib14","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.mvr.2012.12.006","article-title":"Endothelial barrier disruption and recovery is controlled by substrate stiffness","volume":"87","author":"Birukova","year":"2013","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.molimm.2023.02.010_bib15","unstructured":"Bistner, S.I., Ford, R.B., Raffe, M.R., 2002. Manual de procedimentos veterin\u00e1rios e tratamento de emerg\u00eancia. 7. ed. S\u00e3oPaulo: Roca. 934p."},{"key":"10.1016\/j.molimm.2023.02.010_bib16","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/ni.1937","article-title":"Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm","volume":"11","author":"Biswas","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib17","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1369\/0022155419852932","article-title":"Renal inflammation and fibrosis: a double-edged sword","volume":"67","author":"Black","year":"2019","journal-title":"J. Histochem. Cytochem"},{"key":"10.1016\/j.molimm.2023.02.010_bib18","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1038\/ki.1997.190","article-title":"TGF-beta in kidney fibrosis: a target for gene therapy","volume":"51","author":"Border","year":"1997","journal-title":"Kidney Int."},{"key":"10.1016\/j.molimm.2023.02.010_bib19","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1073\/pnas.1613855114","article-title":"Matrix stiffening promotes a tumor vasculature phenotype","volume":"114","author":"Bordeleau","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.molimm.2023.02.010_bib20","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.4049\/jimmunol.164.6.3009","article-title":"Selective suppression of IL-12 production by chemoattractants","volume":"164","author":"Braun","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib21","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/S1471-4922(01)01902-X","article-title":"Chemokines in host-protozoan-parasite interaction","volume":"17","author":"Brenier-Pinchart","year":"2001","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.molimm.2023.02.010_bib22","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1369\/0022155419849388","article-title":"Extracellular matrix in kidney fibrosis: more than just a scaffold","volume":"67","author":"B\u00fclow","year":"2019","journal-title":"J. Histochem. Cytochem"},{"key":"10.1016\/j.molimm.2023.02.010_bib23","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1373\/clinchem.2008.112797","article-title":"The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments","volume":"55","author":"Bustin","year":"2009","journal-title":"Clin. Chem."},{"key":"10.1016\/j.molimm.2023.02.010_bib24","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.actatropica.2008.05.027","article-title":"Human schistosomiasis mansoni: immune responses during acute and chronic phases of the infection","volume":"108","author":"Caldas","year":"2008","journal-title":"Acta Trop."},{"key":"10.1016\/j.molimm.2023.02.010_bib25","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.4049\/jimmunol.163.4.2160","article-title":"Monocyte chemoattractant protein-1 mediates cockroach allergen-induced bronchial hyperreactivity in normal but not CCR2_\/_mice: the role of mast cells","volume":"163","author":"Campbell","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib26","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s12917-018-1524-y","article-title":"Use of acute phase proteins for the clinical assessment and management of canine leishmaniosis: general recommendations","volume":"14","author":"Ceron","year":"2018","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.molimm.2023.02.010_bib27","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1097\/01.mop.0000193287.56528.a4","article-title":"Pathogenesis of renal injury in obstructive uropathies","volume":"18","author":"Chevalier","year":"2006","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1016\/j.molimm.2023.02.010_bib28","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1681\/ASN.2010050510","article-title":"Chemokines in renal injury","volume":"22","author":"Chung","year":"2011","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.molimm.2023.02.010_bib29","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4238\/vol9-1gmr717","article-title":"Caspase-3\/-8\/-9, Bax and Bcl-2 expression in the cerebellum, lymph nodes and leukocytes of dogs naturally infected with canine distemper virus","volume":"9","author":"DelPuerto","year":"2010","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.molimm.2023.02.010_bib30","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1089\/jir.2008.0027","article-title":"Monocyte chemoattractant protein-1 (MCP-1): an overview","volume":"29","author":"Deshmane","year":"2009","journal-title":"J. Interferon Cytokine Res"},{"key":"10.1016\/j.molimm.2023.02.010_bib31","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.mam.2018.06.002","article-title":"Cellular and molecular mechanisms of kidney fibrosis","volume":"65","author":"Djudjaj","year":"2019","journal-title":"Mol. Asp. Med"},{"key":"10.1016\/j.molimm.2023.02.010_bib32","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1152\/jappl.2001.91.4.1487","article-title":"Cytoskeletal regulation of pulmonary vascular permeability","volume":"91","author":"Dudek","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.molimm.2023.02.010_bib33","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1111\/1523-1747.ep12483971","article-title":"Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6","volume":"97","author":"Duncan","year":"1991","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.molimm.2023.02.010_bib34","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s004670000461","article-title":"Molecular basis of renal fibrosis","volume":"15","author":"Eddy","year":"2000","journal-title":"Pediatr. Nephrol."},{"key":"10.1016\/j.molimm.2023.02.010_bib35","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1046\/j.1523-1755.2003.00255.x","article-title":"Plasticity of kidney cells: role in kidney remodelling and scarring","volume":"64","author":"El Nahas","year":"2003","journal-title":"Kidney Int"},{"key":"10.1016\/j.molimm.2023.02.010_bib36","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1002\/(SICI)1521-4141(199802)28:02<669::AID-IMMU669>3.0.CO;2-N","article-title":"Neutralization of IL-12 demonstrates the existence of discrete organ-specific phases in the control of Leishmania donovani","volume":"28","author":"Engwerda","year":"1998","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib37","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1681\/ASN.2009091005","article-title":"Morphometric and visual evaluation of fibrosis in renal biopsies","volume":"22","author":"Farris","year":"2011","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.molimm.2023.02.010_bib38","doi-asserted-by":"crossref","first-page":"4623","DOI":"10.4049\/jimmunol.154.9.4623","article-title":"IL-12 enhances Th1-type responses in human Leishmania donovani infections","volume":"154","author":"Ghalib","year":"1995","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib39","doi-asserted-by":"crossref","first-page":"S76","DOI":"10.1046\/j.1523-1755.63.s84.14.x","article-title":"Uremia-associated immune defect: the IL-10-CRP axis","volume":"84","author":"Girndt","year":"2003","journal-title":"Kidney Int. Suppl."},{"key":"10.1016\/j.molimm.2023.02.010_bib40","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.immuni.2010.05.007","article-title":"Alternative activation of macrophages: mechanism and functions","volume":"32","author":"Gordon","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.molimm.2023.02.010_bib41","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.3389\/fimmu.2019.02759","article-title":"More than just attractive: How CCL2 influences myeloid cell behavior beyond chemotaxis","volume":"10","author":"Gschwandtner","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib42","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/35006097","article-title":"Control of Th2 polarization by the chemokine monocyte chemoattractant protein- 1","volume":"404","author":"Gu","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.molimm.2023.02.010_bib43","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1046\/j.1523-1755.2003.00330.x","article-title":"b-hydroxybutyrate-induced growth inhibition and collagen production in HK-2 cellsare dependent on TGF-b and Smad3","volume":"64","author":"Guh","year":"2003","journal-title":"Kidney Int."},{"key":"10.1016\/j.molimm.2023.02.010_bib44","first-page":"00121","article-title":"Cytokines and their role in health and disease: a brief overview","volume":"4","author":"Gulati","year":"2016","journal-title":"MOJ Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib45","article-title":"Reciprocal interaction between macrophages and T cells stimulates IFN-gamma and MCP-1 production in Ang II-induced cardiac inflammation and fibrosis","volume":"7","author":"Han","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.molimm.2023.02.010_bib46","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s00281-007-0097-9","article-title":"Tipping PG. Leukocytes in glomerular injury","volume":"29","author":"Holdsworth","year":"2007","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.molimm.2023.02.010_bib47","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1159\/000083644","article-title":"Adrenomedullinimpairs the profibrotic effects of transforming growth factorbeta1 throughrecruiting Smad6 protein in human renal tubular cells","volume":"15","author":"Huang","year":"2005","journal-title":"Cell Physiol.Biochem."},{"key":"10.1016\/j.molimm.2023.02.010_bib48","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3002761","article-title":"Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration","volume":"3","author":"Huynh","year":"2011","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.molimm.2023.02.010_bib49","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1128\/IAI.71.8.4278-4288.2003","article-title":"Impaired expression of Inflammatory cytokines and chemokines at early stages of infection with Leishmania amazonensis","volume":"71","author":"Ji","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.molimm.2023.02.010_bib50","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.4049\/jimmunol.148.8.2423","article-title":"Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes","volume":"148","author":"Jiang","year":"1992","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib51","doi-asserted-by":"crossref","first-page":"6011","DOI":"10.4049\/jimmunol.1402797","article-title":"Transcription factors STAT6 and KLF4 implement macrophage polarization via the dual catalytic powers of MCPIP","volume":"194","author":"Kapoor","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib52","doi-asserted-by":"crossref","first-page":"152","DOI":"10.4049\/jimmunol.171.1.152","article-title":"Dendritic cells support sequential reprogramming of chemoattractant receptor profiles during naive to effector T cell differentiation","volume":"171","author":"Kim","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib53","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/hr.2015.62","article-title":"CCL5 upregulates IL-10 expression and partially mediates the antihypertensive effects of IL-10 in the vascular smooth muscle cells of spontaneously hypertensive rats","volume":"38","author":"Kim","year":"2015","journal-title":"Hypertens. Res."},{"key":"10.1016\/j.molimm.2023.02.010_bib54","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1172\/JCI115950","article-title":"Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis","volume":"90","author":"Koch","year":"1992","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.molimm.2023.02.010_bib55","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/ncpneph0418","article-title":"Mechanisms of Disease: regulation of RANTES (CCL5) in renal disease","volume":"3","author":"Krensky","year":"2007","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.molimm.2023.02.010_bib56","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.vetpar.2009.12.033","article-title":"Some remarks about the LeishVet directions for the treatment of canine leishmaniasis","volume":"169","author":"Lamothe","year":"2010","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.molimm.2023.02.010_bib57","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.molimm.2023.02.010_bib58","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1016\/S0021-9258(18)52202-X","article-title":"Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1\/erythroid potentiating activity (TIMP-1\/EPA)","volume":"266","author":"Lotz","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.molimm.2023.02.010_bib59","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1084\/jem.187.4.601","article-title":"Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice","volume":"187","author":"Lu","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.molimm.2023.02.010_bib60","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/84205","article-title":"Chemokines as regulators of T cell differentiation","volume":"2","author":"Luther","year":"2001","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib61","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1161\/01.CIR.0000141561.15939.EC","article-title":"Regulated on activation, normal T cell expressed and secreted (RANTES) antagonist (Met-RANTES) controls the Early phase of Trypanosoma cruzi-elicited myocarditis","volume":"110","author":"Marino","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.molimm.2023.02.010_bib62","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1086\/339260","article-title":"Leishmania-induced cellular recruitment during the early inflammatory response: modulation of proinflammatory mediators","volume":"185","author":"Matte","year":"2002","journal-title":"J. Infect. Dis"},{"key":"10.1016\/j.molimm.2023.02.010_bib63","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2350-12-71","article-title":"No evidence for association between SLC11A1 andvisceral leishmaniasis in India","volume":"12","author":"Mehrotra","year":"2011","journal-title":"BMC med. genet."},{"key":"10.1016\/j.molimm.2023.02.010_bib64","doi-asserted-by":"crossref","first-page":"198","DOI":"10.4269\/ajtmh.2008.79.198","article-title":"Diffuse intralobular liver fibrosis in dogs naturally infected with Leishmania (Leishmania) chagasi","volume":"79","author":"Melo","year":"2008","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.molimm.2023.02.010_bib65","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.vetpar.2010.11.025","article-title":"Cytokine and transcription factor profiles in the skin of dogs naturally infected by Leishmania (Leishmania) chagasi presenting distinct cutaneous parasite density and clinical status","volume":"177","author":"Menezes-Souza","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.molimm.2023.02.010_bib66","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001566","article-title":"Higher expression of CCL2, CCL4, CCL5, CCL21, and CXCL8 chemokines in the skin associated with parasite density in canine visceral leishmaniasis","volume":"6","author":"Menezes-Souza","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"2","key":"10.1016\/j.molimm.2023.02.010_bib67","doi-asserted-by":"crossref","first-page":"F406","DOI":"10.1152\/ajprenal.00099.2004","article-title":"TNF-alphamediates obstruction-induced renal tubular cell apoptosis and pro apoptoticsignaling","volume":"288","author":"Misseri","year":"2005","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.molimm.2023.02.010_bib68","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1590\/S0102-09352004000300020","article-title":"Determination of the minimal representative number of microscopic fields to quantify apoptosis in canine lymph nodes","volume":"56","author":"Moro","year":"2004","journal-title":"Arq. Bras. Med. Vet. Zootec."},{"key":"10.1016\/j.molimm.2023.02.010_bib69","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/nri3073","article-title":"Protective and pathogenic functions of macrophage subsets","volume":"11","author":"Murray","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib70","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1084\/jem.160.2.600","article-title":"Activation of human macrophages. Comparison of Other cytokines with interferon-gamma","volume":"160","author":"Nathan","year":"1984","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.molimm.2023.02.010_bib71","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1038\/ki.1995.443","article-title":"PDGF and TGF-beta contribute to the naturalcourse of human IgA glomerulonephritis","volume":"48","author":"Niemer","year":"1995","journal-title":"Kidney Int."},{"key":"10.1016\/j.molimm.2023.02.010_bib72","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.exppara.2010.02.010","article-title":"Role of chemokines in regulation of immunityagainst leishmaniasis","volume":"126","author":"Oghumu","year":"2010","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.molimm.2023.02.010_bib73","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/00041552-199707000-00014","article-title":"Transforming growth factor-beta in human glomerular injury","volume":"6","author":"Peters","year":"1997","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"10.1016\/j.molimm.2023.02.010_bib74","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1084\/jem.170.3.655","article-title":"Tumor necrosis factor\/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis","volume":"170","author":"Piguet","year":"1989","journal-title":"J. Exp. Med"},{"key":"10.1016\/j.molimm.2023.02.010_bib75","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biocel.2005.09.005","article-title":"The renal cortical fibroblast in renal tubulointerstitial fibrosis","volume":"38","author":"Qi","year":"2006","journal-title":"Int. J. Biochem. Cell. Biol."},{"key":"10.1016\/j.molimm.2023.02.010_bib76","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S1074-7613(00)80149-1","article-title":"Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo","volume":"11","author":"Randolph","year":"1999","journal-title":"Immunity"},{"key":"10.1016\/j.molimm.2023.02.010_bib77","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1046\/j.1365-3024.2002.00467.x","article-title":"Divergent expression of inflammatory dermal chemokines in cutaneous Leishmaniosis","volume":"24","author":"Ritter","year":"2002","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib78","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.1002\/1521-4141(200011)30:11<3111::AID-IMMU3111>3.0.CO;2-O","article-title":"Monocyte chemotactic protein-1 stimulates the killing of Leishmania major by human monocytes, acts synergistically with IFN-_ and is antagonized by IL-4","volume":"30","author":"Ritter","year":"2000","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib79","doi-asserted-by":"crossref","first-page":"3738","DOI":"10.1073\/pnas.85.11.3738","article-title":"Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokinelike properties","volume":"85","author":"Rollins","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.molimm.2023.02.010_bib80","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.4049\/jimmunol.148.7.2148","article-title":"Cytokine-induced production of monocyte chemoattractant protein-1 by cultured human mesangial cells","volume":"148","author":"Rovin","year":"1992","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib81","first-page":"536","article-title":"Glomerular expression of monocyte chemoattractant protein-1 in experimental and human glomerulonephritis","volume":"71","author":"Rovin","year":"1994","journal-title":"Lab. Invest."},{"key":"10.1016\/j.molimm.2023.02.010_bib82","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1159\/000029463","article-title":"Neutrophil inflammation, and activation in bronchiectasis: comparison with pneumonia and idiopathic pulmonary fibrosis","volume":"67","author":"Schaaf","year":"2000","journal-title":"Respiration"},{"key":"10.1016\/j.molimm.2023.02.010_bib83","doi-asserted-by":"crossref","first-page":"F243","DOI":"10.1152\/ajprenal.00300.2002","article-title":"TGF-beta signaltransduction and mesangial cell fibrogenesis","volume":"284","author":"Schnaper","year":"2003","journal-title":"Physiol. Renal. Physiol."},{"key":"10.1016\/j.molimm.2023.02.010_bib84","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1189\/jlb.1107782","article-title":"Pivotal advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation","volume":"83","author":"Shao","year":"2008","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.molimm.2023.02.010_bib85","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/s41420-021-00437-9","article-title":"Role of interleukins in the pathogenesis of pulmonary fibrosis","volume":"7","author":"She","year":"2021","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.molimm.2023.02.010_bib86","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/iep.12010","article-title":"Canine visceral leishmaniasis as a systemic fibrotic disease","volume":"94","author":"Silva","year":"2013","journal-title":"Int J. Exp. Pathol."},{"key":"10.1016\/j.molimm.2023.02.010_bib87","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1089\/wound.2019.1032","article-title":"The role of the anti-Inflammatory cytokine interleukin-10 in tissue fibrosis","volume":"9","author":"Steen","year":"2020","journal-title":"Adv. Wound Care"},{"key":"10.1016\/j.molimm.2023.02.010_bib88","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/nm1685","article-title":"The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak","volume":"14","author":"Tager","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.molimm.2023.02.010_bib89","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/10454411010120020301","article-title":"Involvement of T-lymphocytes in periodontal disease and in direct and indirect induction of bone resorption","volume":"12","author":"Taubman","year":"2001","journal-title":"Crit. Ver. Oral. Biol. Med"},{"key":"10.1016\/j.molimm.2023.02.010_bib90","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1152\/physrev.00024.2005","article-title":"Cytokines in atherosclerosis: Pathogenic and regulatory pathways","volume":"86","author":"Tedgui","year":"2006","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.molimm.2023.02.010_bib91","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.imlet.2017.08.016","article-title":"The phagocyte respiratory burst: historical perspectives and recent advances","volume":"192","author":"Thomas","year":"2017","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.molimm.2023.02.010_bib92","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1016\/S0002-9440(10)61109-1","article-title":"Interaction betweenthe transforming growth factor-beta Type II Receptor\/Smad pathway andbeta-Catenin during transforming growth Factor-beta1-mediated adherens junctiondisassembly","volume":"160","author":"Tian","year":"2002","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.molimm.2023.02.010_bib93","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0952-7915(97)80154-9","article-title":"Cytokines acting on or secreted by macrophages during intracellular infection (IL-10, IL-12, IFN -gamma)","volume":"9","author":"Trinchieri","year":"1997","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib94","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nri1001","article-title":"Interleukin-12 and the regulation of innate resistance and adaptive immunity","volume":"3","author":"Trinchieri","year":"2003","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib95","first-page":"3751","article-title":"A pivotal role for CC chemokine receptor 5 in T-cell migration to tumor sites induced by interleukin 12 treatment in tumor-bearing mice","volume":"62","author":"Uekusa","year":"2002","journal-title":"Cancer Res"},{"key":"10.1016\/j.molimm.2023.02.010_bib96","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/ki.2010.404","article-title":"Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-\u03b2-D-glucosaminidase","volume":"79","author":"Vaidya","year":"2011","journal-title":"Kidney Int"},{"key":"10.1016\/j.molimm.2023.02.010_bib97","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2002-3-7-research0034","article-title":"Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes","volume":"3","author":"Vandesompele","year":"2002","journal-title":"Genome Biol."},{"key":"10.1016\/j.molimm.2023.02.010_bib98","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1172\/JCI31139","article-title":"Systemic sclerosis: a prototypic multisystem fibrotic disorder","volume":"117","author":"Varga","year":"2007","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.molimm.2023.02.010_bib99","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2022.109666","article-title":"Nucleolar organizer region proteins enhancement in nucleoplasm's of renal tubular cells is an indication of kidney impairment in Leishmania-infected dogs","volume":"303","author":"Ver\u00e7osa","year":"2022","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.molimm.2023.02.010_bib100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1746-6148-4-45","article-title":"Transmission potential, skin inflammatory response and parasitism of clinically affected and subclinical infected dogs with visceral Leishmaniosis","volume":"4","author":"Ver\u00e7osa","year":"2008","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.molimm.2023.02.010_bib101","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1590\/S1678-91992011000300011","article-title":"Inflammatory response, parasite load and AgNOR expression in ear skin of clinically affected and subclinical infected L. chagasi infected dogs","volume":"17","author":"Ver\u00e7osa","year":"2011","journal-title":"J. Venom. Anim. Toxins Incl. Trop. Dis."},{"key":"10.1016\/j.molimm.2023.02.010_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2021.109611","article-title":"Enhanced apoptotic index, chemokines and inflammatory recruitment in renal tissues shows relationship with the clinical signs in Leishmania-infected dogs","volume":"300","author":"Ver\u00e7osa","year":"2021","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.molimm.2023.02.010_bib103","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetimm.2021.110196","article-title":"The balance between IL-12\/IL4 in renal tissue switches the inflammatory response arm and shows relationship with the clinical signs in Leishmania-infected dogs","volume":"234","author":"Ver\u00e7osa","year":"2021","journal-title":"Vet. Immun. Immunopath."},{"key":"10.1016\/j.molimm.2023.02.010_bib104","first-page":"1","article-title":"Glomerulosclerosis: the final pathway is clarified, but can we deal with the triggers?","volume":"73","author":"Wardle","year":"1996","journal-title":"Nephron"},{"key":"10.1016\/j.molimm.2023.02.010_bib105","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.matbio.2018.02.020","article-title":"Therapeutic approaches to control tissue repair and fibrosis: Extracellular matrix as a game changer","volume":"71\u201372","author":"Walraven","year":"2018","journal-title":"Matrix Biol."},{"key":"10.1016\/j.molimm.2023.02.010_bib106","unstructured":"World Health Organization - WHO, 2023. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/leishmaniasis, last updatedJanuary 12, 2023, last accessed February 25, 2023."},{"key":"10.1016\/j.molimm.2023.02.010_bib107","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1002\/jbmr.1937","article-title":"Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5)","volume":"28","author":"Wintges","year":"2013","journal-title":"J. Bone Miner. Res"},{"key":"10.1016\/j.molimm.2023.02.010_bib108","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1002\/eji.200940288","article-title":"Macrophage polarization to a unique phenotype driven by B cells","volume":"40","author":"Wong","year":"2010","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib109","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1038\/ki.1997.214","article-title":"Transforming growth factor beta 1 and renal injury following subtotal nephrectomy in the rat: role of the renin-angiotensin system","volume":"51","author":"Wu","year":"1997","journal-title":"Kidney Int"},{"key":"10.1016\/j.molimm.2023.02.010_bib110","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/nri1412","article-title":"Fibrotic disease and the TH1\/TH2 paradigm","volume":"4","author":"Wynn","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib111","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/path.2277","article-title":"Cellular and molecular mechanisms of fibrosis","volume":"214","author":"Wynn","year":"2008","journal-title":"J., Pathol."},{"key":"10.1016\/j.molimm.2023.02.010_bib112","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/ki.1996.65","article-title":"Expression of transforming growth factor-betaisoforms in human glomerular diseases","volume":"49","author":"Yamamoto","year":"1996","journal-title":"Kidney Int."},{"key":"10.1016\/j.molimm.2023.02.010_bib113","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1023\/A:1011059906777","article-title":"IL-12 as well as IL-2 upregulates CCR5 expression on T cell receptor-triggered human CD4_ and CD8_ T cells","volume":"21","author":"Yang","year":"2001","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.molimm.2023.02.010_bib114","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1128\/IAI.71.3.1587-1589.2003","article-title":"Interleukin-12 regulates chemokine gene expression. during the early immune response to Leishmania major","volume":"71","author":"Zaph","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.molimm.2023.02.010_bib115","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/00041552-200105000-00004","article-title":"Renal fibrosis: an update","volume":"10","author":"Zeisberg","year":"2000","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"10.1016\/j.molimm.2023.02.010_bib116","first-page":"S111","article-title":"Role of fibroblast activation in inducing interstitial fibrosis","volume":"13","author":"Zeisberg","year":"2000","journal-title":"J. Nephrol."},{"key":"10.1016\/j.molimm.2023.02.010_bib117","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0002-9440(10)63339-1","article-title":"Renal proximal tubular epithelial cell transforming growth factor beta1 generation and monocyte binding","volume":"165","author":"Zhang","year":"2004","journal-title":"Am. J. Pathol."}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016158902300038X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016158902300038X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:52:04Z","timestamp":1777492324000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016158902300038X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":117,"alternative-id":["S016158902300038X"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2023.02.010","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MCP-1\/IL-12 ratio expressions correlated with adventitial collagen depositions in renal vessels and IL-4\/IFN-\u03b3 expression correlated with interstitial collagen depositions in the kidneys of dogs with canine leishmaniasis","name":"articletitle","label":"Article Title"},{"value":"Molecular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molimm.2023.02.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}