{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T14:27:24Z","timestamp":1782397644664,"version":"3.54.5"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T00:00:00Z","timestamp":1683676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.molimm.2023.05.004","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T05:04:07Z","timestamp":1684731847000},"page":"1-14","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Diagnostic value and underlying mechanism of nasal nitric oxide in eosinophilic chronic rhinosinusitis with nasal polyps"],"prefix":"10.1016","volume":"159","author":[{"given":"Binxiang","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhao","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jieqing","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molimm.2023.05.004_bib1","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1042\/bj3570593","article-title":"Nitric oxide synthases: structure, function and inhibition","volume":"357","author":"Alderton","year":"2001","journal-title":"Biochem J."},{"key":"10.1016\/j.molimm.2023.05.004_bib2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/s11882-012-0247-6","article-title":"Role of medical therapy in the management of nasal polyps","volume":"12","author":"Alobid","year":"2012","journal-title":"Curr. Allergy Asthma Rep."},{"key":"10.1016\/j.molimm.2023.05.004_bib3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ceb.2016.05.006","article-title":"Tight junctions as regulators of tissue remodelling","volume":"42","author":"Balda","year":"2016","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.molimm.2023.05.004_bib4","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.jaci.2009.05.017","article-title":"Distinct immunopathologic characteristics of various types of chronic rhinosinusitis in adult Chinese","volume":"124","author":"Cao","year":"2009","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.molimm.2023.05.004_bib5","first-page":"49","article-title":"Modulation of ciliary activity by tumor necrosis factor-alpha in cultured sinus epithelial cells. Possible roles of nitric oxide","volume":"49","author":"Chen","year":"2000","journal-title":"Hiroshima J. Med. Sci."},{"key":"10.1016\/j.molimm.2023.05.004_bib6","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1046\/j.1365-2222.2002.01379.x","article-title":"Paradoxical low nasal nitric oxide in nasal polyposis","volume":"32","author":"Colantonio","year":"2002","journal-title":"Clin. Exp. Allergy: J. Br. Soc. Allergy Clin. Immunol."},{"key":"10.1016\/j.molimm.2023.05.004_bib7","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/alr.21304","article-title":"Histopathological and clinical analysis of chronic rhinosinusitis by subtype","volume":"4","author":"Czerny","year":"2014","journal-title":"Int. Forum Allergy Rhinol."},{"key":"10.1016\/j.molimm.2023.05.004_bib8","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1164\/rccm.200207-640OC","article-title":"Reduced nitric oxide in sinus epithelium of patients with radiologic maxillary sinusitis and sepsis","volume":"168","author":"Deja","year":"2003","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.molimm.2023.05.004_bib9","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3389\/fmed.2017.00139","article-title":"Interleukin-13 in asthma and other eosinophilic disorders","volume":"4","author":"Doran","year":"2017","journal-title":"Front. Med. (Lausanne)"},{"key":"10.1016\/j.molimm.2023.05.004_bib10","doi-asserted-by":"crossref","first-page":"331","DOI":"10.2147\/JAA.S190489","article-title":"Clinical utility of the exhaled nitric oxide (NO) measurement with portable devices in the management of allergic airway inflammation and asthma","volume":"12","author":"Duong-Quy","year":"2019","journal-title":"J. Asthma Allergy"},{"key":"10.1016\/j.molimm.2023.05.004_bib11","doi-asserted-by":"crossref","unstructured":"Dweik, R.A., Boggs, P.B., Erzurum, S.C., Irvin, C.G., Leigh, M.W., Lundberg, J.O., Olin, A.C., Plummer, A.L., Taylor, D.R., American Thoracic Society Committee on Interpretation of Exhaled Nitric Oxide Levels for Clinical, A., 2011. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am. J. Respir. Crit. Care Med. 184, 602\u2013615.","DOI":"10.1164\/rccm.9120-11ST"},{"key":"10.1016\/j.molimm.2023.05.004_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhin20.401","article-title":"European position paper on rhinosinusitis and nasal polyps 2020","volume":"58","author":"Fokkens","year":"2020","journal-title":"Rhinology"},{"key":"10.1016\/j.molimm.2023.05.004_bib13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.4193\/Rhin17.111","article-title":"Exhaled and nasal nitric oxide in chronic rhinosinusitis patients with nasal polyps in primary care","volume":"56","author":"Frendo","year":"2018","journal-title":"Rhinology"},{"key":"10.1016\/j.molimm.2023.05.004_bib14","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1016\/j.jaci.2020.04.010","article-title":"Epithelial barriers in allergy and asthma","volume":"145","author":"Hellings","year":"2020","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.molimm.2023.05.004_bib15","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1002\/lary.22507","article-title":"Diagnostic significance of blood eosinophil count in eosinophilic chronic rhinosinusitis with nasal polyps in Chinese adults","volume":"122","author":"Hu","year":"2012","journal-title":"Laryngoscope"},{"key":"10.1016\/j.molimm.2023.05.004_bib16","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2020.572749","article-title":"Interleukin-13 alters tight junction proteins expression thereby compromising barrier function and dampens rhinovirus induced immune responses in nasal epithelium","volume":"8","author":"Huang","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.molimm.2023.05.004_bib17","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1080\/1744666X.2019.1601556","article-title":"Epithelial physical barrier defects in chronic rhinosinusitis","volume":"15","author":"Jiao","year":"2019","journal-title":"Expert Rev. Clin. Immunol."},{"key":"10.1016\/j.molimm.2023.05.004_bib18","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s40463-017-0214-2","article-title":"IL-5 and IL-6 are increased in the frontal recess of eosinophilic chronic rhinosinusitis patients","volume":"46","author":"Kubota","year":"2017","journal-title":"J. Otolaryngol. - Head. Neck Surg. = Le. J. D. 'oto-rhino-Laryngol. Et. De. Chir. cervico-Facial"},{"key":"10.1016\/j.molimm.2023.05.004_bib19","article-title":"The correlation between FeNO and nNO in allergic rhinitis and bronchial asthma","volume":"100","author":"Li","year":"2021","journal-title":"Medicine"},{"key":"10.1016\/j.molimm.2023.05.004_bib20","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1111\/all.13411","article-title":"Multidimensional endotypes of chronic rhinosinusitis and their association with treatment outcomes","volume":"73","author":"Liao","year":"2018","journal-title":"Allergy"},{"issue":"1574\u20131581","key":"10.1016\/j.molimm.2023.05.004_bib21","article-title":"Use of nasal nitric oxide in the diagnosis of allergic rhinitis and nonallergic rhinitis in patients with and without sinus inflammation","volume":"8","author":"Liu","year":"2020","journal-title":"J. Allergy Clin. Immunol.\u00a0Pract."},{"key":"10.1016\/j.molimm.2023.05.004_bib22","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1111\/all.13424","article-title":"Role of IL-13R\u03b12 in modulating IL-13-induced MUC5AC and ciliary changes in healthy and CRSwNP mucosa","volume":"73","author":"Liu","year":"2018","journal-title":"Allergy"},{"key":"10.1016\/j.molimm.2023.05.004_bib23","doi-asserted-by":"crossref","first-page":"150","DOI":"10.4193\/Rhino15.271","article-title":"Cellular phenotyping of chronic rhinosinusitis with nasal polyps","volume":"54","author":"Lou","year":"2016","journal-title":"Rhinology"},{"key":"10.1016\/j.molimm.2023.05.004_bib24","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1002\/alr.22214","article-title":"Highlights of eosinophilic chronic rhinosinusitis with nasal polyps in definition, prognosis, and advancement","volume":"8","author":"Lou","year":"2018","journal-title":"Int. Forum Allergy Rhinol."},{"key":"10.1016\/j.molimm.2023.05.004_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2022.115402","article-title":"Chrysophanol prevents IL-1\u03b2-Induced inflammation and ECM degradation in osteoarthritis via the Sirt6\/NF-\u03baB and Nrf2\/NF-\u03baB axis","volume":"208","author":"Lu","year":"2023","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.molimm.2023.05.004_bib26","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1038\/s41390-020-01334-0","article-title":"Necrotizing enterocolitis intestinal barrier function protection by antenatal dexamethasone and surfactant-D in a rat model","volume":"90","author":"Lu","year":"2021","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.molimm.2023.05.004_bib27","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1748-1716.1994.tb09826.x","article-title":"Nasally exhaled nitric oxide in humans originates mainly in the paranasal sinuses","volume":"152","author":"Lundberg","year":"1994","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.molimm.2023.05.004_bib28","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1159\/000509211","article-title":"Predictive and diagnostic value of nasal nitric oxide in eosinophilic chronic rhinosinusitis with nasal polyps","volume":"181","author":"Lv","year":"2020","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.molimm.2023.05.004_bib29","doi-asserted-by":"crossref","first-page":"210","DOI":"10.2500\/aap.2013.34.3660","article-title":"Inflammometry in pediatric asthma: a review of fractional exhaled nitric oxide in clinical practice","volume":"34","author":"Mahr","year":"2013","journal-title":"Allergy Asthma Proc."},{"key":"10.1016\/j.molimm.2023.05.004_bib30","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.2174\/0929867323666160627115335","article-title":"Recent advances on nitric oxide in the upper airways","volume":"23","author":"Maniscalco","year":"2016","journal-title":"Curr. Med Chem."},{"issue":"Suppl 1","key":"10.1016\/j.molimm.2023.05.004_bib31","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1159\/000126066","article-title":"Chronic rhinosinusitis: risk factors for the recurrence of chronic rhinosinusitis based on 5-year follow-up after endoscopic sinus surgery","volume":"146","author":"Matsuwaki","year":"2008","journal-title":"Int Arch. Allergy Immunol."},{"key":"10.1016\/j.molimm.2023.05.004_bib32","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1080\/10715762.2017.1364377","article-title":"Pharmacological modulation of reactive oxygen species (ROS) improves the airway hyperresponsiveness by shifting the Th1 response in allergic inflammation induced by ovalbumin","volume":"51","author":"Nesi","year":"2017","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.molimm.2023.05.004_bib33","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1017\/S0022215116009087","article-title":"Measuring nasal nitric oxide in allergic rhinitis patients","volume":"130","author":"Nesic","year":"2016","journal-title":"J. Laryngol. Otol."},{"key":"10.1016\/j.molimm.2023.05.004_bib34","first-page":"222","article-title":"Classification of chronic rhinosinusitis with nasal polyps based on eosinophilic inflammation","volume":"54","author":"Pan","year":"2019","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"10.1016\/j.molimm.2023.05.004_bib35","doi-asserted-by":"crossref","DOI":"10.1088\/1752-7163\/abc234","article-title":"Extended nitric oxide analysis in patients with chronic rhinosinusitis with nasal polyps, with or without associated asthma","volume":"15","author":"Paoletti","year":"2020","journal-title":"J. Breath. Res."},{"key":"10.1016\/j.molimm.2023.05.004_bib36","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/cea.12881","article-title":"The current and future role of biomarkers in type 2 cytokine-mediated asthma management. Clinical and experimental allergy","volume":"47","author":"Pavord","year":"2017","journal-title":"Clin. Exp. Allergy J. Br. Soc. Allergy Clin. Immunol."},{"key":"10.1016\/j.molimm.2023.05.004_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4193\/Rhin19.410","article-title":"European position paper on diagnostic tools in rhinology","volume":"57","author":"Rimmer","year":"2019","journal-title":"Rhinology"},{"key":"10.1016\/j.molimm.2023.05.004_bib38","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/all.12064","article-title":"Features of airway remodeling in different types of Chinese chronic rhinosinusitis are associated with inflammation patterns","volume":"68","author":"Shi","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.molimm.2023.05.004_bib39","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1164\/rccm.201402-0234OC","article-title":"Disease-specific T-helper cell polarizing function of lesional dendritic cells in different types of chronic rhinosinusitis with nasal polyps","volume":"190","author":"Shi","year":"2014","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.molimm.2023.05.004_bib40","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.otohns.2009.10.005","article-title":"Impact of mucosal eosinophilia and nasal polyposis on quality-of-life outcomes after sinus surgery","volume":"142","author":"Soler","year":"2010","journal-title":"Otolaryngol.-Head. Neck Surg."},{"key":"10.1016\/j.molimm.2023.05.004_bib41","doi-asserted-by":"crossref","first-page":"4859260","DOI":"10.1155\/2020\/4859260","article-title":"The state of the nitric oxide cycle in respiratory tract diseases","volume":"2020","author":"Soodaeva","year":"2020","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.molimm.2023.05.004_bib42","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1002\/JLB.5MR0120-230R","article-title":"Tight junctions in the development of asthma, chronic rhinosinusitis, atopic dermatitis, eosinophilic esophagitis, and inflammatory bowel diseases","volume":"107","author":"Sugita","year":"2020","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.molimm.2023.05.004_bib43","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.anl.2013.02.001","article-title":"Increased exhaled nitric oxide and its oxidation metabolism in eosinophilic chronic rhinosinusitis","volume":"40","author":"Takeno","year":"2013","journal-title":"Auris Nasus Larynx"},{"key":"10.1016\/j.molimm.2023.05.004_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2015.12.1324","article-title":"Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers","volume":"137","author":"Tomassen","year":"2016","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.molimm.2023.05.004_bib45","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1111\/j.1398-9995.2006.01225.x","article-title":"Differentiation of chronic sinus diseases by measurement of inflammatory mediators","volume":"61","author":"Van Zele","year":"2006","journal-title":"Allergy"},{"key":"10.1016\/j.molimm.2023.05.004_bib46","first-page":"8","article-title":"Arginase isoform expression in chronic rhinosinusitis","author":"Vlad","year":"2019","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.molimm.2023.05.004_bib47","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/bph.14527","article-title":"Nitric oxide in the gastrointestinal tract: opportunities for drug development","volume":"176","author":"Wallace","year":"2019","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.molimm.2023.05.004_bib48","doi-asserted-by":"crossref","unstructured":"Wang, J., Kang, X., Huang, Z., Shen, L., Luo, Q., Li, M., Luo, L., Tu, J., Han, M., Ye, J., 2021. Protease-activated receptor-2 decreased zonula occlidens-1 and claudin-1 expression and induced epithelial barrier dysfunction in allergic rhinitis. Am. J. Rhinol. Allergy, 35, 26\u201335.","DOI":"10.1177\/1945892420932486"},{"key":"10.1016\/j.molimm.2023.05.004_bib49","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.jaci.2016.05.041","article-title":"Diversity of T cytokine profiles in patients with chronic rhinosinusitis: a multicenter study in Europe, Asia, and Oceania","volume":"138","author":"Wang","year":"2016","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.molimm.2023.05.004_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102590","article-title":"Targeted delivery of Nitric Oxide triggered by \u03b1-Glucosidase to Ameliorate NSAIDs-induced Enteropathy","volume":"59","author":"Wang","year":"2023","journal-title":"Redox Biol."},{"key":"10.1016\/j.molimm.2023.05.004_bib51","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/978-3-030-74180-8_10","article-title":"Role of L-arginine in nitric oxide synthesis and health in humans","volume":"1332","author":"Wu","year":"2021","journal-title":"Adv. Exp. Med Biol."},{"key":"10.1016\/j.molimm.2023.05.004_bib52","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1517\/13543776.2014.979154","article-title":"Nitric oxide synthase inhibitors: a review of patents from 2011 to the present","volume":"25","author":"Yang","year":"2015","journal-title":"Expert Opin. Ther. Pat."},{"key":"10.1016\/j.molimm.2023.05.004_bib53","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.alit.2018.09.005","article-title":"Reduced nasal nitric oxide levels in patients with eosinophilic chronic rhinosinusitis","volume":"68","author":"Yoshida","year":"2019","journal-title":"Allergol. Int"},{"key":"10.1016\/j.molimm.2023.05.004_bib54","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/BF03401781","article-title":"Inducible nitric oxide synthase and inflammatory diseases","volume":"6","author":"Zamora","year":"2000","journal-title":"Mol. Med. (Camb., Mass. )"},{"key":"10.1016\/j.molimm.2023.05.004_bib55","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/alr.22636","article-title":"The role of preoperative blood eosinophil counts in distinguishing chronic rhinosinusitis with nasal polyps phenotypes","volume":"11","author":"Zhong","year":"2021","journal-title":"Int Forum Allergy Rhinol."},{"key":"10.1016\/j.molimm.2023.05.004_bib56","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s40463-020-00465-y","article-title":"The roles of nasal nitric oxide in diagnosis and endotypes of chronic rhinosinusitis with nasal polyps","volume":"49","author":"Zhu","year":"2020","journal-title":"J. Otolaryngol. Head. Neck Surg."},{"key":"10.1016\/j.molimm.2023.05.004_bib57","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.jcmgh.2020.04.001","article-title":"Tight junctions as targets and effectors of mucosal immune homeostasis","volume":"10","author":"Zuo","year":"2020","journal-title":"Cell. Mol. Gastroenterol. Hepatol."}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589023000998?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589023000998?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T13:44:56Z","timestamp":1758980696000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589023000998"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":57,"alternative-id":["S0161589023000998"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2023.05.004","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic value and underlying mechanism of nasal nitric oxide in eosinophilic chronic rhinosinusitis with nasal polyps","name":"articletitle","label":"Article Title"},{"value":"Molecular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molimm.2023.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}