{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:18:33Z","timestamp":1786994313306,"version":"build-2736575974"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.molimm.2023.06.009","type":"journal-article","created":{"date-parts":[[2023,7,6]],"date-time":"2023-07-06T08:16:07Z","timestamp":1688631367000},"page":"112-120","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Analysis of CD8+ TCR\u03b2 Chain repertoire in peripheral blood of vitiligo via high-throughput sequencing"],"prefix":"10.1016","volume":"160","author":[{"given":"Hao","family":"Xiong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyan","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianji","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengmeng","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangren","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7335-7110","authenticated-orcid":false,"given":"Xiuqin","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.molimm.2023.06.009_bib1","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1111\/j.1365-2133.2007.08211.x","article-title":"T-cell receptor repertoire in pyoderma gangrenosum: evidence for clonal expansions and trafficking","volume":"157","author":"Brooklyn","year":"2007","journal-title":"Br. J. Dermatol."},{"issue":"2","key":"10.1016\/j.molimm.2023.06.009_bib2","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1002\/med.21754","article-title":"Mechanisms of melanocyte death in vitiligo","volume":"41","author":"Chen","year":"2021","journal-title":"Med. Res. Rev."},{"issue":"11","key":"10.1016\/j.molimm.2023.06.009_bib3","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1021\/pr060363j","article-title":"Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes","volume":"5","author":"Chi","year":"2006","journal-title":"J. Proteome Res."},{"issue":"6","key":"10.1016\/j.molimm.2023.06.009_bib4","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.humimm.2018.03.007","article-title":"Characterization of peripheral blood TCR repertoire in patients with ankylosing spondylitis by high-throughput sequencing","volume":"79","author":"Cui","year":"2018","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.molimm.2023.06.009_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.639672","article-title":"Comprehensive analysis of CDR3 sequences in gluten-specific T-Cell receptors reveals a dominant R-Motif and several new minor motifs","volume":"12","author":"Dahal-Koirala","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.molimm.2023.06.009_bib6","doi-asserted-by":"crossref","first-page":"856","DOI":"10.3389\/fimmu.2019.00856","article-title":"The emerging epigenetic role of CD8+T cells in autoimmune diseases: a systematic review","volume":"10","author":"Deng","year":"2019","journal-title":"Front. Immunol."},{"issue":"9988","key":"10.1016\/j.molimm.2023.06.009_bib7","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0140-6736(14)60763-7","article-title":"Vitiligo","volume":"386","author":"Ezzedine","year":"2015","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.molimm.2023.06.009_bib8","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1365-2249.2008.03763.x","article-title":"Skew in T cell receptor usage with polyclonal expansion in lesions of oral lichen planus without hepatitis C virus infection","volume":"154","author":"Gotoh","year":"2008","journal-title":"Clin. Exp. Immunol."},{"issue":"1","key":"10.1016\/j.molimm.2023.06.009_bib9","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1158\/2326-6066.CIR-19-0398","article-title":"TCR Repertoire Diversity of Peripheral PD-1+CD8+ T cells predicts clinical outcomes after immunotherapy in patients with non\u2013small cell lung cancer","volume":"8","author":"Han","year":"2020","journal-title":"Cancer Immunol. Res."},{"issue":"8","key":"10.1016\/j.molimm.2023.06.009_bib10","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1002\/art.41252","article-title":"Altered repertoire diversity and disease-associated clonal expansions revealed by T cell receptor immunosequencing in ankylosing spondylitis patients","volume":"72","author":"Hanson","year":"2020","journal-title":"Arthritis Rheuma"},{"issue":"19","key":"10.1016\/j.molimm.2023.06.009_bib11","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.121949","article-title":"High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata","volume":"3","author":"de Jong","year":"2018","journal-title":"JCI Insight"},{"issue":"3","key":"10.1016\/j.molimm.2023.06.009_bib12","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/pcmr.12458","article-title":"Functional cloning of a gp100-reactive T-cell receptor from vitiligo patient skin","volume":"29","author":"Klarquist","year":"2016","journal-title":"Pigment Cell Melanoma Res."},{"key":"10.1016\/j.molimm.2023.06.009_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.739413","article-title":"Clinical significance of serum oxidative stress markers to assess disease activity and severity in patients with non-segmental vitiligo","volume":"9","author":"Li","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"3","key":"10.1016\/j.molimm.2023.06.009_bib14","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1159\/000511893","article-title":"Identification of candidate genes and pathways in nonsegmental vitiligo using integrated bioinformatics methods","volume":"237","author":"Liu","year":"2021","journal-title":"Dermatology"},{"issue":"8","key":"10.1016\/j.molimm.2023.06.009_bib15","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1136\/annrheumdis-2019-215442","article-title":"T cell receptor beta repertoires as novel diagnostic markers for systemic lupus erythematosus and rheumatoid arthritis","volume":"78","author":"Liu","year":"2019","journal-title":"Ann. Rheum. Dis."},{"issue":"6","key":"10.1016\/j.molimm.2023.06.009_bib16","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1084\/jem.188.6.1203","article-title":"High frequency of skin-homing melanocyte-specific cytotoxic T lymphocytes in autoimmune vitiligo","volume":"188","author":"Ogg","year":"1998","journal-title":"J. Exp. Med."},{"issue":"8","key":"10.1016\/j.molimm.2023.06.009_bib17","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/s41592-021-01201-8","article-title":"High-throughput and single-cell T cell receptor sequencing technologies","volume":"18","author":"Pai","year":"2021","journal-title":"Nat. Methods"},{"issue":"6","key":"10.1016\/j.molimm.2023.06.009_bib18","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.coi.2013.10.010","article-title":"Innate immune mechanisms in vitiligo: danger from within","volume":"25","author":"Richmond","year":"2013","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.molimm.2023.06.009_bib19","doi-asserted-by":"crossref","first-page":"8081","DOI":"10.1038\/ncomms9081","article-title":"High-resolution analysis of the human T-cell receptor repertoire","volume":"6","author":"Ruggiero","year":"2015","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.molimm.2023.06.009_bib20","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/pcmr.12949","article-title":"An update on Vitiligo pathogenesis","volume":"34","author":"Seneschal","year":"2021","journal-title":"Pigment Cell Melanoma Res."},{"key":"10.1016\/j.molimm.2023.06.009_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2020.102574","article-title":"Longitudinal analysis of T-cell receptor repertoires reveals persistence of antigen-driven CD4(+) and CD8(+) T-cell clusters in systemic sclerosis","volume":"117","author":"Servaas","year":"2021","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.molimm.2023.06.009_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.568447","article-title":"Autoimmunity in Segmental Vitiligo","volume":"11","author":"Speeckaert","year":"2020","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.molimm.2023.06.009_bib23","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1111\/pcmr.12974","article-title":"Vitiligo: translational research and effective therapeutic strategies","volume":"34","author":"Thakur","year":"2021","journal-title":"Pigment Cell Melanoma Res."},{"issue":"12","key":"10.1016\/j.molimm.2023.06.009_bib24","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abe0013","article-title":"Massive clonal expansion of polycytotoxic skin and blood CD8(+) T cells in patients with toxic epidermal necrolysis","volume":"7","author":"Villani","year":"2021","journal-title":"Sci. Adv."},{"issue":"2","key":"10.1016\/j.molimm.2023.06.009_bib25","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/imcb.12377","article-title":"The human T-cell receptor repertoire in health and disease and potential for omics integration","volume":"99","author":"Watkins","year":"2021","journal-title":"Immunol. Cell Biol."},{"issue":"10","key":"10.1016\/j.molimm.2023.06.009_bib26","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/gm502","article-title":"Sequence analysis of T-cell repertoires in health and disease","volume":"5","author":"Woodsworth","year":"2013","journal-title":"Genome Med."},{"issue":"5","key":"10.1016\/j.molimm.2023.06.009_bib27","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1038\/s41385-018-0046-z","article-title":"Expanded TCRbeta CDR3 clonotypes distinguish Crohn's disease and ulcerative colitis patients","volume":"11","author":"Wu","year":"2018","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.molimm.2023.06.009_bib28","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.molimm.2019.01.002","article-title":"Comprehensive assessment of T cell receptor \u03b2 repertoire in Stevens-Johnson syndrome\/toxic epidermal necrolysis patients using high-throughput sequencing","volume":"106","author":"Xiong","year":"2019","journal-title":"Mol. Immunol."},{"issue":"3","key":"10.1016\/j.molimm.2023.06.009_bib29","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/s41423-020-0367-1","article-title":"Structural understanding of T cell receptor triggering","volume":"17","author":"Xu","year":"2020","journal-title":"Cell Mol. Immunol."},{"issue":"7891","key":"10.1016\/j.molimm.2023.06.009_bib30","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/s41586-021-04221-8","article-title":"Anatomically distinct fibroblast subsets determine skin autoimmune patterns","volume":"601","author":"Xu","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.molimm.2023.06.009_bib31","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.3389\/fimmu.2020.01618","article-title":"High-Throughput sequencing-based analysis of T cell repertoire in Lupus Nephritis","volume":"11","author":"Ye","year":"2020","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.molimm.2023.06.009_bib32","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1001\/jamadermatol.2019.4483","article-title":"Association of clinical markers with disease progression in patients with vitiligo from China","volume":"156","author":"Zhang","year":"2020","journal-title":"JAMA Dermatol."}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589023001311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589023001311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T13:46:54Z","timestamp":1758980814000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589023001311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":32,"alternative-id":["S0161589023001311"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2023.06.009","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analysis of CD8+ TCR\u03b2 Chain repertoire in peripheral blood of vitiligo via high-throughput sequencing","name":"articletitle","label":"Article Title"},{"value":"Molecular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molimm.2023.06.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}