{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T02:02:53Z","timestamp":1793844173553,"version":"4.6.1"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81772002"],"award-info":[{"award-number":["81772002"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010877","name":"Shenzhen Science and Technology Innovation Commission","doi-asserted-by":"publisher","award":["JCYJ20230808104859039"],"award-info":[{"award-number":["JCYJ20230808104859039"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010877","name":"Shenzhen Science and Technology Innovation Commission","doi-asserted-by":"publisher","award":["JCYJ20170818092553608"],"award-info":[{"award-number":["JCYJ20170818092553608"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.molimm.2024.05.011","type":"journal-article","created":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T09:35:51Z","timestamp":1718098551000},"page":"23-37","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration"],"prefix":"10.1016","volume":"172","author":[{"given":"Hua","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cai","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenglan","family":"Nie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuling","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengqing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinyao","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunpeng","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molimm.2024.05.011_bib1","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1056\/NEJMra0804647","article-title":"Mechanisms of disease inflammatory bowel disease","volume":"361","author":"Abraham","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.molimm.2024.05.011_bib2","doi-asserted-by":"crossref","DOI":"10.1038\/srep29783","article-title":"Cross-talk between intestinal epithelial cells and immune cells in inflammatory bowel disease","volume":"6","author":"Al-Ghadban","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.molimm.2024.05.011_bib3","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD007571.pub2","article-title":"Vedolizumab for induction and maintenance of remission in ulcerative colitis","author":"Bickston","year":"2014","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.molimm.2024.05.011_bib4","doi-asserted-by":"crossref","first-page":"2948","DOI":"10.1097\/MIB.0000000000000631","article-title":"New applications for traditional drugs in inflammatory bowel disease: what do cochrane reviews tell us?","volume":"21","author":"Chande","year":"2015","journal-title":"Inflamm. Bowel Dis."},{"key":"10.1016\/j.molimm.2024.05.011_bib5","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/bem.21971","article-title":"Early exposure of rotating magnetic fields promotes central nervous regeneration in planarian Girardia sinensis","volume":"37","author":"Chen","year":"2016","journal-title":"Bioelectromagnetics"},{"key":"10.1016\/j.molimm.2024.05.011_bib6","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.phymed.2016.03.016","article-title":"Agrimonolide from Agrimonia pilosa suppresses inflammatory responses through down-regulation of COX-2\/iNOS and inactivation of NF-\u03baB in lipopolysaccharide-stimulated macrophages","volume":"23","author":"Chen","year":"2016","journal-title":"Phytomedicine"},{"key":"10.1016\/j.molimm.2024.05.011_bib7","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/ibd\/izy313","article-title":"A practical guide to the safety and monitoring of new IBD therapies","volume":"25","author":"Click","year":"2019","journal-title":"Inflamm. Bowel Dis."},{"key":"10.1016\/j.molimm.2024.05.011_bib8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0378-4274(00)00259-9","article-title":"Differential effects of low frequency, low intensity (< 6 mG) nocturnal magnetic fields upon infiltration of mononuclear cells and numbers of mast cells in lewis rat brains","volume":"118","author":"Cook","year":"2000","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.molimm.2024.05.011_bib9","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.lfs.2008.10.007","article-title":"Phosphodiesterase inhibition attenuates alterations to the tight junction proteins occludin and ZO-1 in immunostimulated Caco-2 intestinal monolayers","volume":"84","author":"Costantini","year":"2009","journal-title":"Life Sci."},{"key":"10.1016\/j.molimm.2024.05.011_bib10","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1136\/gutjnl-2012-303903","article-title":"Mesenchymal stromal cells in inflammatory bowel disease: conspirators within the 'colitogenic niche'?","volume":"62","author":"Danese","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.molimm.2024.05.011_bib11","doi-asserted-by":"crossref","first-page":"180","DOI":"10.3109\/15368378.2012.695706","article-title":"Exposure to ELF- magnetic field promotes restoration of sensori-motor functions in adult rats with hemisection of thoracic spinal cord","volume":"31","author":"Das","year":"2012","journal-title":"Electromagn. Biol. Med."},{"key":"10.1016\/j.molimm.2024.05.011_bib12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nrgastro.2015.186","article-title":"Immunopathogenesis of IBD: current state of the art","volume":"13","author":"De Souza","year":"2016","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.molimm.2024.05.011_bib13","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1152\/japplphysiol.00536.2015","article-title":"Intestinal epithelial barrier function and tight junction proteins with heat and exercise","volume":"120","author":"Dokladny","year":"2016","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.molimm.2024.05.011_bib14","first-page":"11","article-title":"Inflammatory biomarkers of extracellular matrix remodeling and disease activity in crohn's disease and ulcerative colitis","author":"Domislovic","year":"2022","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.molimm.2024.05.011_bib15","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1136\/gut.48.4.526","article-title":"The risk of colorectal cancer in ulcerative colitis: a meta-analysis","volume":"48","author":"Eaden","year":"2001","journal-title":"Gut"},{"key":"10.1016\/j.molimm.2024.05.011_bib16","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1159\/000007822","article-title":"Characterisation of acute murine dextran sodium sulphate colitis:: cytokine profile and dose dependency","volume":"62","author":"Egger","year":"2000","journal-title":"Digestion"},{"key":"10.1016\/j.molimm.2024.05.011_bib17","doi-asserted-by":"crossref","first-page":"S653","DOI":"10.1016\/S0016-5085(13)62420-8","article-title":"Inflammatory bowel disease: low impact on scores of quality of life, depression and anxiety in patients attending a tertiary care center in Brazil","volume":"144","author":"Flores","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.molimm.2024.05.011_bib18","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/s41575-018-0081-y","article-title":"Tales from the crypt: new insights into intestinal stem cells","volume":"16","author":"Gehart","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.molimm.2024.05.011_bib19","doi-asserted-by":"crossref","DOI":"10.3390\/cells12070972","article-title":"Rotating magnetic field mitigates ankylosing spondylitis targeting osteocytes and chondrocytes via ameliorating immune dysfunctions","volume":"12","author":"Han","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.molimm.2024.05.011_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2020.153179","article-title":"Wogonoside alleviates colitis by improving intestinal epithelial barrier function via the MLCK\/pMLC2 pathway","volume":"68","author":"Huang","year":"2020","journal-title":"Phytomedicine"},{"key":"10.1016\/j.molimm.2024.05.011_bib21","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aat0852","article-title":"PAI-1 augments mucosal damage in colitis","volume":"11","author":"Kaiko","year":"2019","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.molimm.2024.05.011_bib22","doi-asserted-by":"crossref","first-page":"352","DOI":"10.5606\/tftrd.2019.2899","article-title":"The effect of magnetic field therapy and electric stimulation on experimental burn healing","volume":"65","author":"Keskin","year":"2019","journal-title":"Turk. J. Phys. Med. Rehabil."},{"key":"10.1016\/j.molimm.2024.05.011_bib23","doi-asserted-by":"crossref","first-page":"604","DOI":"10.5851\/kosfa.2015.35.5.604","article-title":"The synergic anti-inflammatory impact of gleditsia sinensis lam. and lactobacillus brevis KY21 on intestinal epithelial cells in a DSS-induced colitis model","volume":"35","author":"Kim","year":"2015","journal-title":"Korean J. Food Sci. Anim. Resour."},{"key":"10.1016\/j.molimm.2024.05.011_bib24","article-title":"Ulcerative colitis","volume":"6","author":"Kobayashi","year":"2020","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.molimm.2024.05.011_bib25","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1093\/ibd\/izaa125","article-title":"Mast cell tryptase promotes inflammatory bowel disease-induced intestinal fibrosis","volume":"27","author":"Liu","year":"2021","journal-title":"Inflamm. Bowel Dis."},{"key":"10.1016\/j.molimm.2024.05.011_bib26","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1128\/IAI.00455-13","article-title":"Escherichia coli Heat-Stable Toxin b Impairs Intestinal Epithelial Barrier Function by Altering Tight Junction Proteins","volume":"81","author":"Mukiza","year":"2013","journal-title":"Infect. Immun."},{"key":"10.1016\/j.molimm.2024.05.011_bib27","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.jocd.2017.06.002","article-title":"Water treatment by magnetic field increases bone mineral density of rats","volume":"20","author":"Neto","year":"2017","journal-title":"J. Clin. Densitom."},{"key":"10.1016\/j.molimm.2024.05.011_bib28","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1038\/s41590-019-0415-0","article-title":"Targeting immune cell circuits and trafficking in inflammatory bowel disease","volume":"20","author":"Neurath","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.molimm.2024.05.011_bib29","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/0016-5085(90)90290-H","article-title":"A novel method in the induction of reliable experimental acute and chronic ulcerative-colitis in mice","volume":"98","author":"Okayasu","year":"1990","journal-title":"Gastroenterology"},{"key":"10.1016\/j.molimm.2024.05.011_bib30","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/nri3608","article-title":"Intestinal epithelial cells: regulators of barrier function and immune homeostasis","volume":"14","author":"Peterson","year":"2014","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.molimm.2024.05.011_bib31","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1056\/NEJMoa050516","article-title":"Infliximab for induction and maintenance therapy for ulcerative colitis","volume":"353","author":"Rutgeerts","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.molimm.2024.05.011_bib32","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1053\/j.gastro.2017.11.276","article-title":"Pyrin inflammasome regulates tight junction integrity to restrict colitis and tumorigenesis","volume":"154","author":"Sharma","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.molimm.2024.05.011_bib33","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.cell.2019.06.029","article-title":"Intra- and inter-cellular rewiring of the human colon during ulcerative colitis","volume":"178","author":"Smillie","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.molimm.2024.05.011_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.crohns.2007.11.001","article-title":"European evidence-based Consensus on the diagnosis and management of ulcerative colitis: Definitions and diagnosis","volume":"2","author":"Stange","year":"2008","journal-title":"J. Crohns Colitis"},{"key":"10.1016\/j.molimm.2024.05.011_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.compbiomed.2021.104600","article-title":"Investigation of the plaque morphology effect on changes of pulsatile blood flow in a stenosed curved artery induced by an external magnetic field","volume":"135","author":"Teimouri","year":"2021","journal-title":"Comput. Biol. Med."},{"key":"10.1016\/j.molimm.2024.05.011_bib36","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.1097\/MIB.0b013e3182a85709","article-title":"Increased prevalence of circulating novel IL-17 secreting Foxp3 expressing CD4+T cells and defective suppressive function of circulating Foxp3+regulatory cells support plasticity between Th17 and regulatory T cells in inflammatory bowel disease patients","volume":"19","author":"Ueno","year":"2013","journal-title":"Inflamm. Bowel Dis."},{"key":"10.1016\/j.molimm.2024.05.011_bib37","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1016\/S0140-6736(16)32126-2","article-title":"Ulcerative colitis","volume":"389","author":"Ungaro","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.molimm.2024.05.011_bib38","doi-asserted-by":"crossref","first-page":"117","DOI":"10.4103\/0019-5413.50844","article-title":"Bone stimulation for fracture healing: Whats all the fuss","volume":"43","author":"Victoria","year":"2009","journal-title":"Indian J. Orthop."},{"key":"10.1016\/j.molimm.2024.05.011_bib39","doi-asserted-by":"crossref","first-page":"S463-S463","DOI":"10.1016\/S0016-5085(13)61712-6","article-title":"Canonical Wnt signals combined with suppressed TGFbeta\/BMP pathways promote renewal of the native human colonic epithelium","volume":"144","author":"Wharton","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.molimm.2024.05.011_bib40","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/s41423-021-00810-9","article-title":"The deubiquitinase OTUD1 inhibits colonic inflammation by suppressing RIPK1-mediated NE-\u03baB signaling.","volume":"19","author":"Wu","year":"2022","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.molimm.2024.05.011_bib41","doi-asserted-by":"crossref","first-page":"927","DOI":"10.2217\/nnm-2019-0071","article-title":"What potential do magnetic iron oxide nanoparticles have for the treatment of rheumatoid arthritis?","volume":"14","author":"Wu","year":"2019","journal-title":"Nanomedicine"},{"key":"10.1016\/j.molimm.2024.05.011_bib42","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.apsb.2020.12.018","article-title":"Biological drug and drug delivery-mediated immunotherapy","volume":"11","author":"Xiao","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.molimm.2024.05.011_bib43","doi-asserted-by":"crossref","first-page":"6634","DOI":"10.3748\/wjg.v25.i45.6634","article-title":"Toxoplasma ROP16 ameliorated inflammatory bowel diseases via inducing M2 phenotype of macrophages","volume":"25","author":"Xu","year":"2019","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.molimm.2024.05.011_bib44","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.biopha.2016.04.037","article-title":"Anti-inflammatory effect of taurocholate on TNBS-induced ulcerative colitis in mice","volume":"81","author":"Yang","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.molimm.2024.05.011_bib45","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.18632\/aging.103018","article-title":"Rotating magnetic field ameliorates experimental autoimmune encephalomveigis by promoting T cell peripheral accumulation and regulating the oalance of Treg and Th1\/Th17","volume":"12","author":"Zhan","year":"2020","journal-title":"Aging-Us"},{"key":"10.1016\/j.molimm.2024.05.011_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/bem.20165","article-title":"Effects of 0.4 T rotating magnetic field exposure on density, strength, calcium and metabolism of rat thigh bones","volume":"27","author":"Zhang","year":"2006","journal-title":"Bioelectromagnetics"}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589024001020?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589024001020?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T23:28:34Z","timestamp":1721172514000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589024001020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":46,"alternative-id":["S0161589024001020"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2024.05.011","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration","name":"articletitle","label":"Article Title"},{"value":"Molecular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molimm.2024.05.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}