{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:36:41Z","timestamp":1779928601703,"version":"3.53.1"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","award":["BMU2021MX020"],"award-info":[{"award-number":["BMU2021MX020"]}],"id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","award":["BMU2022MX008"],"award-info":[{"award-number":["BMU2022MX008"]}],"id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82270736"],"award-info":[{"award-number":["82270736"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Immunology"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.molimm.2025.02.008","type":"journal-article","created":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T07:15:19Z","timestamp":1740554119000},"page":"44-54","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["C-reactive protein attenuates CCl4-induced acute liver injury by regulating complement system activation"],"prefix":"10.1016","volume":"180","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2468-0918","authenticated-orcid":false,"given":"Zhao-Ming","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Geng","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Xin","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ze-Rui","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiu-Yu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Yun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.molimm.2025.02.008_bib1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.intimp.2014.05.014","article-title":"Carbon tetrachloride-induced hepatotoxicity in rat is reversed by treatment with riboflavin","volume":"21","author":"Al-Harbi","year":"2014","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.molimm.2025.02.008_bib2","unstructured":"Alobaidi, L., (2012).molecular cloning, phylogenetic analysis, and expression of two immune related genes, serum amyloid a and c-reactive protein from asian seabass Lates calcarifer."},{"key":"10.1016\/j.molimm.2025.02.008_bib3","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/s41572-019-0105-0","article-title":"Drug-induced liver injury","volume":"5","author":"Andrade","year":"2019","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.molimm.2025.02.008_bib4","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S0140-6736(10)60274-7","article-title":"Acute liver failure","volume":"376","author":"Bernal","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.molimm.2025.02.008_bib5","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms14188","article-title":"Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites","volume":"8","author":"Braig","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.molimm.2025.02.008_bib6","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/imr.12350","article-title":"Mouse and human FcR effector functions","volume":"268","author":"Bruhns","year":"2015","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.molimm.2025.02.008_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.133543","article-title":"Oxidative stress responses of microplastic-contaminated Gambusia affinis obtained from the Brantas River in East Java, Indonesia","volume":"293","author":"Buwono","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.molimm.2025.02.008_bib8","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jhep.2022.10.028","article-title":"Hepatocyte-specific Mas activation enhances lipophagy and fatty acid oxidation to protect against acetaminophen-induced hepatotoxicity in mice","volume":"78","author":"Chen","year":"2023","journal-title":"J. Hepatol."},{"key":"10.1016\/j.molimm.2025.02.008_bib9","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1038\/s42003-022-03220-3","article-title":"Secretory quality control constrains functional selection-associated protein structure innovation","volume":"5","author":"Cheng","year":"2022","journal-title":"Commun. Biol."},{"key":"10.1016\/j.molimm.2025.02.008_bib10","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1186\/s12951-023-01942-y","article-title":"Mesenchymal stem cell-derived exosomal miR-27b-3p alleviates liver fibrosis via downregulating YAP\/LOXL2 pathway","volume":"21","author":"Cheng","year":"2023","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.molimm.2025.02.008_bib11","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/path.4766","article-title":"Monomeric C-reactive protein and inflammation in age-related macular degeneration","volume":"240","author":"Chirco","year":"2016","journal-title":"J. Pathol."},{"key":"10.1016\/j.molimm.2025.02.008_bib12","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1080\/10937404.2023.2220147","article-title":"Evaluation of the carcinogenicity of carbon tetrachloride","volume":"26","author":"Cohen","year":"2023","journal-title":"J. Toxicol. Environ. Health B Crit. Rev."},{"key":"10.1016\/j.molimm.2025.02.008_bib13","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1038\/s41419-018-1136-2","article-title":"Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis","volume":"9","author":"Dai","year":"2018","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.molimm.2025.02.008_bib14","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.3389\/fimmu.2018.01921","article-title":"Monomeric C-reactive protein and cerebral hemorrhage: from bench to bedside","volume":"9","author":"Di Napoli","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.molimm.2025.02.008_bib15","doi-asserted-by":"crossref","first-page":"2818","DOI":"10.1111\/all.14413","article-title":"Mast cells and complement system: ancient interactions between components of innate immunity","volume":"75","author":"Elieh Ali Komi","year":"2020","journal-title":"Allergy"},{"key":"10.1016\/j.molimm.2025.02.008_bib16","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1084\/jem.192.9.1353","article-title":"C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implications for systemic autoimmunity","volume":"192","author":"Gershov","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.molimm.2025.02.008_bib17","doi-asserted-by":"crossref","first-page":"3957","DOI":"10.4049\/jimmunol.163.7.3957","article-title":"Regulation of complement activation by C-reactive protein: targeting the complement inhibitory activity of factor H by an interaction with short consensus repeat domains 7 and 8-11","volume":"163","author":"Jarva","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2025.02.008_bib18","doi-asserted-by":"crossref","first-page":"699","DOI":"10.4049\/jimmunol.2200831","article-title":"C-reactive protein: the most familiar stranger","volume":"210","author":"Ji","year":"2023","journal-title":"J. Immunol."},{"key":"10.1016\/j.molimm.2025.02.008_bib19","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.freeradbiomed.2004.09.017","article-title":"Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?","volume":"38","author":"Kadiiska","year":"2005","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.molimm.2025.02.008_bib20","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/s41575-020-00372-7","article-title":"Molecular and cellular mechanisms of liver fibrosis and its regression","volume":"18","author":"Kisseleva","year":"2021","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.molimm.2025.02.008_bib21","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev-immunol-051116-052415","article-title":"Immune responses in the liver","volume":"36","author":"Kubes","year":"2018","journal-title":"Annu Rev. Immunol."},{"key":"10.1016\/j.molimm.2025.02.008_bib22","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1053\/j.gastro.2012.09.008","article-title":"Sterile inflammation in the liver","volume":"143","author":"Kubes","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.molimm.2025.02.008_bib23","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.jcmgh.2021.01.001","article-title":"Complement-5 inhibition deters progression of fulminant hepatitis to acute liver failure in murine models","volume":"11","author":"Kusakabe","year":"2021","journal-title":"Cell Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.molimm.2025.02.008_bib24","doi-asserted-by":"crossref","first-page":"3044","DOI":"10.1681\/ASN.2016070735","article-title":"Autoantibodies against C-reactive protein influence complement activation and clinical course in lupus nephritis","volume":"28","author":"Li","year":"2017","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.molimm.2025.02.008_bib25","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jcmgh.2021.09.003","article-title":"C-reactive protein protects against Acetaminophen-induced liver injury by preventing complement overactivation","volume":"13","author":"Li","year":"2022","journal-title":"Cell Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.molimm.2025.02.008_bib26","doi-asserted-by":"crossref","first-page":"111","DOI":"10.2478\/jtim-2023-0085","article-title":"Suggestions on home quarantine and recovery of novel coronavirus patients","volume":"11","author":"Li","year":"2023","journal-title":"J. Transl. Int. Med."},{"key":"10.1016\/j.molimm.2025.02.008_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.113164","article-title":"Monocyte-derived Kupffer cells dominate in the Kupffer cell pool during liver injury","volume":"42","author":"Li","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.molimm.2025.02.008_bib28","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/cmi.2017.147","article-title":"IL-33 induces immunosuppressive neutrophils via a type 2 innate lymphoid cell\/IL-13\/STAT6 axis and protects the liver against injury in LCMV infection-induced viral hepatitis","volume":"16","author":"Liang","year":"2019","journal-title":"Cell Mol. Immunol."},{"key":"10.1016\/j.molimm.2025.02.008_bib29","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1021\/jf304562b","article-title":"Sesamin protects mouse liver against nickel-induced oxidative DNA damage and apoptosis by the PI3K-Akt pathway","volume":"61","author":"Liu","year":"2013","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.molimm.2025.02.008_bib30","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1038\/nature07468","article-title":"Structural recognition and functional activation of FcgammaR by innate pentraxins","volume":"456","author":"Lu","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.molimm.2025.02.008_bib31","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.ccell.2018.09.003","article-title":"Complement C5a fosters squamous carcinogenesis and limits T cell response to chemotherapy","volume":"34","author":"Medler","year":"2018","journal-title":"Cancer Cell"},{"key":"10.1016\/j.molimm.2025.02.008_bib32","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1146\/annurev.immunol.21.120601.141011","article-title":"IgA Fc receptors","volume":"21","author":"Monteiro","year":"2003","journal-title":"Annu Rev. Immunol."},{"key":"10.1016\/j.molimm.2025.02.008_bib33","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3389\/fimmu.2019.00166","article-title":"Structure-function relationships of C-reactive protein in bacterial infection","volume":"10","author":"Ngwa","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.molimm.2025.02.008_bib34","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1172\/JCI200318921","article-title":"C-reactive protein: a critical update","volume":"111","author":"Pepys","year":"2003","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.molimm.2025.02.008_bib35","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1007\/s00281-021-00892-7","article-title":"Tipping the balance: intricate roles of the complement system in disease and therapy","volume":"43","author":"Pouw","year":"2021","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.molimm.2025.02.008_bib36","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1161\/01.ATV.0000171983.95612.90","article-title":"Role of C-reactive protein in atherogenesis: can the apolipoprotein E knockout mouse provide the answer?","volume":"25","author":"Reifenberg","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.molimm.2025.02.008_bib37","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.jhep.2018.10.015","article-title":"Impaired endothelial autophagy promotes liver fibrosis by aggravating the oxidative stress response during acute liver injury","volume":"70","author":"Ruart","year":"2019","journal-title":"J. Hepatol."},{"key":"10.1016\/j.molimm.2025.02.008_bib38","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/nature00858","article-title":"Release of chromatin protein HMGB1 by necrotic cells triggers inflammation","volume":"418","author":"Scaffidi","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.molimm.2025.02.008_bib39","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/imr.12475","article-title":"Protection of host cells by complement regulators","volume":"274","author":"Schmidt","year":"2016","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.molimm.2025.02.008_bib40","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.freeradbiomed.2024.05.004","article-title":"TREM2 protects against inflammation by regulating the release of mito-DAMPs from hepatocytes during liver fibrosis","volume":"220","author":"Shan","year":"2024","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.molimm.2025.02.008_bib41","doi-asserted-by":"crossref","first-page":"752","DOI":"10.7150\/ijbs.40612","article-title":"Hepatoprotective effect of Citrus aurantium L. Against APAP-induced liver injury by regulating liver lipid metabolism and apoptosis","volume":"16","author":"Shu","year":"2020","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.molimm.2025.02.008_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2023.102998","article-title":"Conformational state of C-reactive protein is critical for reducing immune complex-triggered type I interferon response: implications for pathogenic mechanisms in autoimmune diseases imprinted by type I interferon gene dysregulation","volume":"135","author":"Svanberg","year":"2023","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.molimm.2025.02.008_bib43","article-title":"Animal models of C-reactive protein","volume":"2014","author":"Torzewski","year":"2014","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.molimm.2025.02.008_bib44","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1038\/s41589-023-01339-w","article-title":"Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins","volume":"19","author":"Wang","year":"2023","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.molimm.2025.02.008_bib45","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/713611034","article-title":"Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model","volume":"33","author":"Weber","year":"2003","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.molimm.2025.02.008_bib46","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12731","article-title":"TIM-4 interference in Kupffer cells against CCL4-induced liver fibrosis by mediating Akt1\/Mitophagy signalling pathway","volume":"53","author":"Wu","year":"2020","journal-title":"Cell Prolif."},{"key":"10.1016\/j.molimm.2025.02.008_bib47","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/s41423-023-00983-5","article-title":"Mesenchymal stromal cells in hepatic fibrosis\/cirrhosis: from pathogenesis to treatment","volume":"20","author":"Yang","year":"2023","journal-title":"Cell Mol. Immunol."},{"key":"10.1016\/j.molimm.2025.02.008_bib48","article-title":"The role of the NLRP3 inflammasome and programmed cell death in acute liver injury","volume":"24","author":"Yu","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.molimm.2025.02.008_bib49","doi-asserted-by":"crossref","first-page":"33","DOI":"10.52601\/bpr.2023.230001","article-title":"GNA12 regulates C5a-induced migration by downregulating C5aR1-PLCbeta2-PI3K-AKT-ERK1\/2 signaling","volume":"9","author":"Yu","year":"2023","journal-title":"Biophys. Rep."},{"key":"10.1016\/j.molimm.2025.02.008_bib50","article-title":"Hepatitis B virus infection","volume":"4","author":"Yuen","year":"2018","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.molimm.2025.02.008_bib51","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1182\/blood-2006-12-063636","article-title":"Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo","volume":"110","author":"Zhang","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.molimm.2025.02.008_bib52","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1038\/s41467-024-46135-9","article-title":"Deficiency of ASGR1 promotes liver injury by increasing GP73-mediated hepatic endoplasmic reticulum stress","volume":"15","author":"Zhang","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.molimm.2025.02.008_bib53","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1002\/hep.30563","article-title":"Tissue repair in the mouse liver following acute carbon tetrachloride depends on injury-induced Wnt\/beta-catenin signaling","volume":"69","author":"Zhao","year":"2019","journal-title":"Hepatology"}],"container-title":["Molecular Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589025000392?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161589025000392?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,9]],"date-time":"2025-03-09T03:37:53Z","timestamp":1741491473000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161589025000392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":53,"alternative-id":["S0161589025000392"],"URL":"https:\/\/doi.org\/10.1016\/j.molimm.2025.02.008","relation":{},"ISSN":["0161-5890"],"issn-type":[{"value":"0161-5890","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"C-reactive protein attenuates CCl4-induced acute liver injury by regulating complement system activation","name":"articletitle","label":"Article Title"},{"value":"Molecular Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.molimm.2025.02.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}